Curcumin inhibits the proteinase-activated receptor-2-triggered prostaglandin E2 production by suppressing cyclooxygenase-2 upregulation and Akt-dependent activation of nuclear factor-κB in human lung epithelial cells

Journal of Pharmacological Sciences

Volumn 114, Issue 2, 2010, Pages 225-229

  Moriyuki, Kazumi ^a   Sekiguchi, Fumiko ^a   Matsubara, Kaori ^a   Nishikawa, Hiroyuki ^a   Kawabata, Atsufumi ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Curcumin; Proteinase activated receptor 2

Indexed keywords

CURCUMIN; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 2;

ARTICLE; CARCINOMA CELL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM; PROSTAGLANDIN RELEASE; PROTEIN FUNCTION;

EID: 78349286717     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10126SC     Document Type: Article

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