Counteracting effect of TRPC1-associated CA2+ influx on TNF-α-induced COX-2-dependent prostaglandin E2 production in human colonic myofibroblasts

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 301, Issue 2, 2011, Pages

  Hai, Lin ^a   Kawarabayashi, Yasuhiro ^a   Imai, Yuko ^a   Honda, Akira ^a   Inoue, Ryuji ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Ca2+ signaling; Cyclooxygenase 2; Cytokine; Inflammation; NF B; Nuclear factor of activated T cell proteins; Transient receptor potential

Indexed keywords

CALCIUM ION; CURCUMIN; CYCLOOXYGENASE 2; GANGLIOSIDE GD3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTAGLANDIN E2; SMALL INTERFERING RNA; SN 50; TACROLIMUS; TRANSCRIPTION FACTOR NFAT; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CALCIUM TRANSPORT; CELL NUCLEUS; COLON; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; ION CONDUCTANCE; MYOFIBROBLAST; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE; COLON; CYCLOOXYGENASE 2; DINOPROSTONE; HUMANS; MYOFIBROBLASTS; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; RNA, MESSENGER; RNA, SMALL INTERFERING; TRPC CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79960975534     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00354.2010     Document Type: Article

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