Vaccinated mice remain more susceptible to Mycobacterium tuberculosis infection initiated via the respiratory route than via the intravenous route

Infection and Immunity

Volumn 67, Issue 4, 1999, Pages 2010-2012

  North, Robert J ^a   Lacourse, Ronald ^a   Ryan, Lynn ^a  

^a TRUDEAU INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ANTIGENICITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BCG VACCINATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; IMMUNIZATION; LUNG INFECTION; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; TUBERCULOSIS;

EID: 0033003283     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/.67.4.2010-2012.1999     Document Type: Article

References (10)

1. Boom, W. H. 1996. The role of T cell subsets in Mycobacterium tuberculosis infection. Infect. Agents Dis. 5:73-81.
2. Dunn, P. L., and R. J. North. 1995. Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice. Infect. Immun. 63:3428-3437.
3. Dunn, P. L., and R. J. North. 1996. Persistent infection with virulent but not with avirulent Mycobacterium tuberculosis in the lungs of mice causes progressive pathology. J. Med. Microbiol. 45:103-109.
4. Huygen, K., J. Content, O. Denis, D. L. Montgomery, A. M. Yawman, R. R. Deck, C. M. DeWitt, I. M. Orme, S. Baldwin, C. DeSouza, A. Drowart, E. Lozes, P. Vandenbussche, J.-P. V. Vooren, M. A. Liu, and J. B. Ulmer. 1996. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat. Med. 2:893-898.
5. Kaufmann, S. H., C. H. Ladel, and I. E. Flesch. 1995. T cells and cytokines in intracellular bacterial infections: experiences with Mycobacterium bovis BCG. Ciba Found. Symp. 195:132-136.
6. North, R. J. 1995. Mycobacterium tuberculosis is strikingly more virulent for mice when given via the respiratory than via the intravenous route. J. Infect. Dis. 172:1550-1553.
7. Orme, I. M., P. Andersen, and W. H. Boom. 1993. T cell response to Mycobacterium tuberculosis. J. Infect. Dis. 167:1481-1497.
8. Schell, R. F., W. F. Ealey, G. E. Harding, and D. W. Smith. 1974. The influence of vaccination on the course of experimental airborne tuberculosis in mice. J. Reticuloendothel. Soc. 16:131-138.
9. Smith, D. W., D. N. McMurray, E. H. Wiegeshaus, A. A. Grover, and G. E. Harding. Host-parasite relationships in experimental airborne tuberculosis. IV. Early events in the course of infection in vaccinated and nonvaccinuted guinea pigs. Am. Rev. Respir. Dis. 102:937-949.
10. Smith, D. W. 1985. Protective effect of BCG in experimental tuberculosis. Adv. Tuberc. Res. 22:1-99.