Aberrant T helper 17 cells and related cytokines in bone marrow microenvironment of patients with acute myeloid leukemia

Clinical and Developmental Immunology

Volumn 2013, Issue , 2013, Pages

  Tian, Tian ^a   Yu, Shuang ^a   Wang, Min ^a   Yuan, Cunzhong ^a   Zhang, Hua ^b   Ji, Chunyan ^a   Ma, Daoxin ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; CYTARABINE; CYTOKINE; GAMMA INTERFERON; IDARUBICIN; INTERLEUKIN 17; INTERLEUKIN 6; RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BLOOD LEVEL; BONE MARROW; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; MICROENVIRONMENT; PATHOGENESIS; PLASMA; PRIORITY JOURNAL; RELAPSE; TH17 CELL; BLOOD; CASE CONTROL STUDY; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; MIDDLE AGED; PATHOLOGY; REMISSION; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT; VERY ELDERLY; YOUNG ADULT; LEUKEMIA, MYELOID, ACUTE;

ADULT; AGED; AGED, 80 AND OVER; BONE MARROW; CASE-CONTROL STUDIES; CYTOKINES; FEMALE; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; REMISSION INDUCTION; TH17 CELLS; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT; YOUNG ADULT;

EID: 84884239451     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2013/915873     Document Type: Article

References (38)

1. Löwenberg B., Downing J. R., Burnett A., Acute myeloid leukemia. The New England Journal of Medicine 1999 341 14 1051 1062 2-s2.0-0345713156 10.1056/NEJM199909303411407
2. Estey E., Döhner H., Acute myeloid leukaemia. The Lancet 2006 368 9550 1894 1907 2-s2.0-33751267902 10.1016/S0140-6736(06)69780-8
3. Fritsche-Polanz R., Fritz M., Huber A., Sotlar K., Sperr W. R., Mannhalter C., Födinger M., Valent P., High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816V. Molecular Oncology 2010 4 4 335 346 2-s2.0-77955275396 10.1016/j.molonc.2010.04.008
4. Barrett A. J., Le Blanc K., Immunotherapy prospects for acute myeloid leukaemia. Clinical and Experimental Immunology 2010 161 2 223 232 2-s2.0-77954635822 10.1111/j.1365-2249.2010.04197.x
5. Mangan P. R., Harrington L. E., O'Quinn D. B., Helms W. S., Bullard D. C., Elson C. O., Hatton R. D., Wahl S. M., Schoeb T. R., Weaver C. T., Transforming growth factor- β induces development of the T H17 lineage. Nature 2006 441 7090 231 234 2-s2.0-33646560950 10.1038/nature04754
6. Harrington L. E., Hatton R. D., Mangan P. R., Turner H., Murphy T. L., Murphy K. M., Weaver C. T., Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunology 2005 6 11 1123 1132 2-s2.0-27544490377 10.1038/ni1254
7. Park H., Li Z., Yang X. O., Chang S. H., Nurieva R., Wang Y., Wang Y., Hood L., Zhu Z., Tian Q., Dong C., A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunology 2005 6 11 1133 1141 2-s2.0-27544465354 10.1038/ni1261
8. Bettelli E., Carrier Y., Gao W., Korn T., Strom T. B., Oukka M., Weiner H. L., Kuchroo V. K., Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441 7090 235 238 2-s2.0-33646577466 10.1038/nature04753
9. Veldhoen M., Hocking R. J., Atkins C. J., Locksley R. M., Stockinger B., TGF β in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 24 2 179 189 2-s2.0-32244442562 10.1016/j.immuni.2006.01.001
10. Lee Y., Awasthi A., Yosef N., Induction and molecular signature of pathogenic TH17 cells. Nature Immunology 2012 13 991 999
11. Ivanov I. I., McKenzie B. S., Zhou L., Tadokoro C. E., Lepelley A., Lafaille J. J., Cua D. J., Littman D. R., The orphan nuclear receptor ROR γ t directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006 126 6 1121 1133 2-s2.0-33748588423 10.1016/j.cell.2006.07.035
12. McGeachy M. J., Cua D. J., Th17 cell differentiation: the long and winding road. Immunity 2008 28 4 445 453 2-s2.0-41549134361 10.1016/j.immuni. 2008.03.001
13. Volpe E., Servant N., Zollinger R., Bogiatzi S. I., Hupé P., Barillot E., Soumelis V., A critical function for transforming growth factor- β interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses. Nature Immunology 2008 9 6 650 657 2-s2.0-44049102724 10.1038/ni.1613
14. Acosta-Rodriguez E. V., Napolitani G., Lanzavecchia A., Sallusto F., Interleukins 1 β and 6 but not transforming growth factor- β are essential for the differentiation of interleukin 17-producing human T helper cells. Nature Immunology 2007 8 9 942 949 2-s2.0-34548125305 10.1038/ni1496
15. Cua D. J., Sherlock J., Chen Y., Murphy C. A., Joyce B., Seymour B., Lucian L., To W., Kwan S., Churakova T., Zurawski S., Wiekowski M., Lira S. A., Gorman D., Kastelein R. A., Sedgwick J. D., Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003 421 6924 744 748 2-s2.0-0037434789 10.1038/nature01355
16. Murphy C. A., Langrish C. L., Chen Y., Blumenschein W., McClanahan T., Kastelein R. A., Sedgwick J. D., Cua D. J., Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. Journal of Experimental Medicine 2003 198 12 1951 1957 2-s2.0-0346962972 10.1084/jem.20030896
17. Hirota K., Hashimoto M., Yoshitomi H., Tanaka S., Nomura T., Yamaguchi T., Iwakura Y., Sakaguchi N., Sakaguchi S., T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. Journal of Experimental Medicine 2007 204 1 41 47 2-s2.0-33846456970 10.1084/jem.20062259
18. Kebir H., Kreymborg K., Ifergan I., Dodelet-Devillers A., Cayrol R., Bernard M., Giuliani F., Arbour N., Becher B., Prat A., Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nature Medicine 2007 13 10 1173 1175 2-s2.0-34948909646 10.1038/nm1651
19. Fitch E., Harper E., Skorcheva I., Kurtz S. E., Blauvelt A., Pathophysiology of psoriasis: recent advances on IL-23 and TH17 cytokines. Current Rheumatology Reports 2007 9 6 461 467 2-s2.0-37349131221 10.1007/s11926-007-0075-1
20. Schmechel S., Konrad A., Diegelmann J., Glas J., Wetzke M., Paschos E., Lohse P., Göke B., Brand S., Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflammatory Bowel Diseases 2008 14 2 204 212 2-s2.0-39649121919 10.1002/ibd.20315
21. Miossec P., Interleukin-17 in fashion, at last: ten years after its description, its cellular source has been identified. Arthritis and Rheumatism 2007 56 7 2111 2115 2-s2.0-34547415613 10.1002/art.22733
22. Schwarzenberger P., Kolls J. K., Interleukin 17: an example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis. Journal of Cellular Biochemistry 2002 85 38 88 95 2-s2.0-0036361437 10.1002/jcb.10054
23. Tesmer L. A., Lundy S. K., Sarkar S., Fox D. A., Th17 cells in human disease. Immunological Reviews 2008 223 1 87 113 2-s2.0-47249128991 10.1111/j.1600-065X.2008.00628.x
24. Sfanos K. S., Bruno T. C., Maris C. H., Xu L., Thoburn C. J., Demarzo A. M., Meeker A. K., Isaacs W. B., Drake C. G., Phenotypic analysis of prostate-infiltrating lymphocytes reveals T H17 and Treg skewing. Clinical Cancer Research 2008 14 11 3254 3261 2-s2.0-48849103649 10.1158/1078-0432.CCR- 07-5164
25. Kryczek I., Wei S., Zou L., Altuwaijri S., Szeliga W., Kolls J., Chang A., Zou W., Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. Journal of Immunology 2007 178 11 6730 6733 2-s2.0-34249806717
26. Kryczek I., Banerjee M., Cheng P., Vatan L., Szeliga W., Wei S., Huang E., Finlayson E., Simeone D., Welling T. H., Chang A., Coukos G., Liu R., Zou W., Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009 114 6 1141 1149 2-s2.0-69849107597 10.1182/blood-2009-03-208249
27. Zhang Y., Ma D., Zhang Y., Tian Y., Wang X., Qiao Y., Cui B., The imbalance of Th17/Treg in patients with uterine cervical cancer. Clinica Chimica Acta 2011 412 11-12 894 900 2-s2.0-79955004068 10.1016/j.cca.2011.01.015
28. Wu C., Wang S., Wang F., Chen Q., Peng S., Zhang Y., Qian J., Jin J., Xu H., Increased frequencies of T helper type 17 cells in the peripheral blood of patients with acute myeloid leukaemia. Clinical and Experimental Immunology 2009 158 2 199 204 2-s2.0-70349690173 10.1111/j.1365-2249.2009.04011.x
29. Fan Z. G., Zhang L. S., Chai Y., Zeng P. Y., Wu C. Y., The prevalence of Th17 cells in patients with acute myeloid leukemia. Zhonghua Xue Ye Xue Za Zhi 2010 31 617 620
30. Bennett J. M., Catovsky D., Daniel M. T., Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. British Journal of Haematology 1976 33 451 458
31. Cheson B. D., Cassileth P. A., Head D. R., Schiffer c. A., Bennett J. M., Bloomfield C. D., Brunning R., Gale R. P., Grever M. R., Keating M. J., Sawitsky A., Stass S., Weinstein H., Woods W. G., Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia. Journal of Clinical Oncology 1990 8 5 813 819 2-s2.0-0025261428
32. Hu Y., Li H., Zhang L., Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia. Human Immunology 2012 73 629 635
33. Maruyama T., Kono K., Mizukami Y., Kawaguchi Y., Mimura K., Watanabe M., Izawa S., Fujii H., Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer. Cancer Science 2010 101 9 1947 1954 2-s2.0-77955938173 10.1111/j.1349-7006.2010.01624.x
34. Shao L. L., Zhang L., Hou Y., Th22 cells as well as Th17 cells expand differentially in patients with early-stage and late-stage myelodysplastic syndrome. PLoS ONE 2012 7 e51339
35. Takatori H., Kanno Y., Watford W. T., Tato C. M., Weiss G., Ivanov I. I., Littman D. R., O'Shea J. J., Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. Journal of Experimental Medicine 2009 206 1 35 41 2-s2.0-60549102720 10.1084/jem.20072713
36. Yang L., Anderson D. E., Baecher-Allan C., Hastings W. D., Bettelli E., Oukka M., Kuchroo V. K., Hafler D. A., IL-21 and TGF- β are required for differentiation of human T H17 cells. Nature 2008 454 7202 350 352 2-s2.0-47549112840 10.1038/nature07021
37. Manel N., Unutmaz D., Littman D. R., The differentiation of human TH-17 cells requires transforming growth factor- β and induction of the nuclear receptor ROR γ t. Nature Immunology 2008 9 6 641 649 2-s2.0-44049104564 10.1038/ni.1610
38. Testa U., Masciulli R., Tritarelli E., Pustorino R., Mariani G., Martucci R., Barberi T., Camagna A., Valtieri M., Peschle C., Transforming growth factor- β potentiates vitamin D3-induced terminal monocytic differentiation of human leukemic cell lines. Journal of Immunology 1993 150 6 2418 2430 2-s2.0-0027196196