Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

Inflammatory Bowel Diseases

Volumn 14, Issue 2, 2008, Pages 204-212

  Schmechel, Silke ^a   Konrad, Astrid ^a   Diegelmann, Julia ^a   Glas, Jürgen ^a   Wetzke, Martin ^a,b   Paschos, Ekaterini ^a   Lohse, Peter ^a   Göke, Burkhard ^a   Brand, Stephan ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

CARD15; Crohn's disease; Genetics; IL 17A; IL 17F; IL 22; IL 23R; IL 6; Inflammatory bowel disease; NOD2; Polymorphism; Th17 cells; TNF ; Ulcerative colitis

Indexed keywords

C REACTIVE PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CYTOKINE; INTERLEUKIN 17A; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; CELL FUNCTION; COMPARATIVE STUDY; CONTROLLED STUDY; CROHN DISEASE; CROHN DISEASE ACTIVITY INDEX; CYTOKINE PRODUCTION; DISEASE ACTIVITY; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN VARIANT; RECEPTOR GENE; RECEPTOR UPREGULATION; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CROHN DISEASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERMANY; HUMANS; INTERLEUKINS; MALE; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 39649121919     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20315     Document Type: Article

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