Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 45, 2006, Pages 16846-16851

  Anikeeva, Nadia ^a   Lebedeva, Tatiana ^a   Clapp, Aaron R ^b   Goldman, Ellen R ^b   Dustin, Michael L ^c   Mattoussi, Hedi ^b   Sykulev, Yuri ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NAVAL RESEARCH LABORATORY   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antivirus immunity; CD8 coreceptor; Peptide MHC clustering; Sensitivity of T cell responses

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR; VIRUS ANTIGEN; VIRUS PROTEIN;

ANTIGEN SPECIFICITY; ARTICLE; BIOSENSOR; CD8+ T LYMPHOCYTE; CONJUGATE; CYTOTOXIC T LYMPHOCYTE; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NANOCRYSTAL; NONHUMAN; PRIORITY JOURNAL; QUANTUM DOT; SEMICONDUCTOR; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS CELL INTERACTION;

ANTIGENS, CD8; ANTIGENS, VIRAL; AUTOANTIGENS; BIOSENSING TECHNIQUES; CLONE CELLS; HLA-A2 ANTIGEN; HUMANS; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; QUANTUM DOTS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 33750939446     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607771103     Document Type: Article

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