T cell activation results in conformational changes in the Src family kinase Lck to induce its activation

Science Signaling

Volumn 6, Issue 263, 2013, Pages

  Stirnweiss, Anja ^a,e   Hartig, Roland ^a   Gieseler, Steffi ^a   Lindquist, Jonathan A ^a   Reichardt, Peter ^a   Philipsen, Lars ^a   Simeoni, Luca ^a   Poltorak, Mateusz ^a   Merten, Camilla ^a   Zuschratter, Werner ^b   Prokazov, Yury ^b   Paster, Wolfgang ^c,f   Stockinger, Hannes ^c   Harder, Thomas ^a   Gunzer, Matthias ^a,g   Schraven, Burkhart ^a,d  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; PROTEIN KINASE LCK; PROTEIN TYROSINE KINASE; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; BIOSENSOR; CELL MATURATION; CHEMICAL ANALYSIS; CONFORMATION; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; FLUORESCENCE IMAGING; KINETICS; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; SIGNAL NOISE RATIO; SPATIOTEMPORAL ANALYSIS; T LYMPHOCYTE ACTIVATION;

BIOSENSING TECHNIQUES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICROSCOPY, FLUORESCENCE; PROTEIN CONFORMATION; T-LYMPHOCYTES;

EID: 84874245378     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003607     Document Type: Article

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