-
1
-
-
1642617697
-
Cardiotoxicity of cytotoxic drugs
-
Schimmel K.J., Richel D.J., van den Brink R.B., Guchelaar H.J. Cardiotoxicity of cytotoxic drugs. Cancer Treat Rev 2004, 30:181-191.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 181-191
-
-
Schimmel, K.J.1
Richel, D.J.2
van den Brink, R.B.3
Guchelaar, H.J.4
-
2
-
-
2642566088
-
Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G., Menna P., Salvatorelli E., Cairo G., Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 2004, 56:185-229.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
3
-
-
0026714331
-
The anthracyclines: will we ever find a better doxorubicin?
-
Weiss R.B. The anthracyclines: will we ever find a better doxorubicin?. Semin Oncol 1992, 19:670-686.
-
(1992)
Semin Oncol
, vol.19
, pp. 670-686
-
-
Weiss, R.B.1
-
4
-
-
67649958842
-
Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management
-
Yeh E.T., Bickford C.L. Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management. J Am Coll Cardiol 2009, 53(24):2231-2247.
-
(2009)
J Am Coll Cardiol
, vol.53
, Issue.24
, pp. 2231-2247
-
-
Yeh, E.T.1
Bickford, C.L.2
-
5
-
-
49249135889
-
Anthracycline cardiotoxicity: from bench to bedside
-
Gianni L., Herman E.H., Lipshultz S.E., Minotti G., Sarvazyan N., Sawyer D.B. Anthracycline cardiotoxicity: from bench to bedside. J Clin Oncol 2008, 26(22):3777-3784.
-
(2008)
J Clin Oncol
, vol.26
, Issue.22
, pp. 3777-3784
-
-
Gianni, L.1
Herman, E.H.2
Lipshultz, S.E.3
Minotti, G.4
Sarvazyan, N.5
Sawyer, D.B.6
-
6
-
-
0017755691
-
Adriamycin cardiomyopathy risk factors
-
Minow R.A., Benjamin R.S., Lee E.T., Gottlieb J.A. Adriamycin cardiomyopathy risk factors. Cancer 1977, 39(4):1397-1402.
-
(1977)
Cancer
, vol.39
, Issue.4
, pp. 1397-1402
-
-
Minow, R.A.1
Benjamin, R.S.2
Lee, E.T.3
Gottlieb, J.A.4
-
7
-
-
0034044815
-
Adriamycin-induced heart failure: mechanism and modulation
-
Singal P.K., Li T., Kumar D., Danelisen I., Iliskovic N. Adriamycin-induced heart failure: mechanism and modulation. Mol Cell Biochem 2000, 207(1-2):77-86.
-
(2000)
Mol Cell Biochem
, vol.207
, Issue.1-2
, pp. 77-86
-
-
Singal, P.K.1
Li, T.2
Kumar, D.3
Danelisen, I.4
Iliskovic, N.5
-
8
-
-
84884209973
-
-
People's Medical Publishing House, Ltd, USA, 2 Edition, January 1
-
Ewer M.S., Yeh E.T.H. Cancer and the Heart 2013, People's Medical Publishing House, Ltd, USA, 2 Edition, January 1. Second Edition.
-
(2013)
Cancer and the Heart
-
-
Ewer, M.S.1
Yeh, E.T.H.2
-
9
-
-
70450260555
-
Cardiomyocyte death in doxorubicin-induced cardiotoxicity
-
Zhang Y.W., Shi J., Li Y.J., Wei L. Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Arch Immunol Ther Exp 2009, 57:435-445.
-
(2009)
Arch Immunol Ther Exp
, vol.57
, pp. 435-445
-
-
Zhang, Y.W.1
Shi, J.2
Li, Y.J.3
Wei, L.4
-
10
-
-
84858693977
-
Anthracycline cardiotoxicity
-
Menna P., Paz O.G., Chello M., Covino E., Salvatorelli E., Minotti G. Anthracycline cardiotoxicity. Expert Opin Drug Saf 2012, 11(Suppl.1):S21-S36.
-
(2012)
Expert Opin Drug Saf
, vol.11
, Issue.SUPPL.1
-
-
Menna, P.1
Paz, O.G.2
Chello, M.3
Covino, E.4
Salvatorelli, E.5
Minotti, G.6
-
11
-
-
84860523994
-
Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies
-
Octavia Y., Tocchetti C.G., Gabrielson K.L., Janssens S., Crijns H.J., Moens A.L. Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies. J Mol Cell Cardiol 2012, 52:1213-1225.
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 1213-1225
-
-
Octavia, Y.1
Tocchetti, C.G.2
Gabrielson, K.L.3
Janssens, S.4
Crijns, H.J.5
Moens, A.L.6
-
12
-
-
66949171305
-
Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron
-
Simunek T., Sterba M., Popelova O., Adamcova M., Hrdina R., Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep 2009, 61:154-171.
-
(2009)
Pharmacol Rep
, vol.61
, pp. 154-171
-
-
Simunek, T.1
Sterba, M.2
Popelova, O.3
Adamcova, M.4
Hrdina, R.5
Gersl, V.6
-
13
-
-
76749108960
-
Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group
-
Salzer W.L., Devidas M., Carroll W.L., Winick N., Pullen J., Hunger S.P., et al. Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group. Leukemia 2010, 24:355-370.
-
(2010)
Leukemia
, vol.24
, pp. 355-370
-
-
Salzer, W.L.1
Devidas, M.2
Carroll, W.L.3
Winick, N.4
Pullen, J.5
Hunger, S.P.6
-
14
-
-
33947542048
-
Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin's disease
-
Tebbi C.K., London W.B., Friedman D., Villaluna D., De Alarcon P.A., Constine L.S., et al. Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin's disease. J Clin Oncol 2007, 25:493-500.
-
(2007)
J Clin Oncol
, vol.25
, pp. 493-500
-
-
Tebbi, C.K.1
London, W.B.2
Friedman, D.3
Villaluna, D.4
De Alarcon, P.A.5
Constine, L.S.6
-
15
-
-
68149169047
-
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts
-
Sardao V.A., Oliveira P.J., Holy J., Oliveira C.R., Wallace K.B. Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemother Pharmacol 2009, 64:811-827.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 811-827
-
-
Sardao, V.A.1
Oliveira, P.J.2
Holy, J.3
Oliveira, C.R.4
Wallace, K.B.5
-
16
-
-
79957532361
-
Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53
-
Zhang C., Feng Y., Qu S., Wei X., Zhu H., Luo Q., et al. Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53. Cardiovasc Res 2011, 90:38-545.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 38-545
-
-
Zhang, C.1
Feng, Y.2
Qu, S.3
Wei, X.4
Zhu, H.5
Luo, Q.6
-
17
-
-
34548785032
-
Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane
-
Lyu Y.L., Kerrigan J.E., Lin C.P., Azarova A.M., Tsai Y.C., Ban Y., et al. Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane. Cancer Res 2007, 67:8839-8846.
-
(2007)
Cancer Res
, vol.67
, pp. 8839-8846
-
-
Lyu, Y.L.1
Kerrigan, J.E.2
Lin, C.P.3
Azarova, A.M.4
Tsai, Y.C.5
Ban, Y.6
-
18
-
-
84869209094
-
Identification of the molecular basis of doxorubicin-induced cardiotoxicity
-
Zhang S., Liu X., Bawa-Khalfe T., Lu L.S., Lyu Y.L., Liu L.F., et al. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med 2012, 18:1639-1642.
-
(2012)
Nat Med
, vol.18
, pp. 1639-1642
-
-
Zhang, S.1
Liu, X.2
Bawa-Khalfe, T.3
Lu, L.S.4
Lyu, Y.L.5
Liu, L.F.6
-
19
-
-
84871219987
-
Effects of doxorubicin cancer therapy on autophagy and the ubiquitin-proteasome system in long-term cultured adult rat cardiomyocytes
-
Dimitrakis P., Romay-Ogando M.I., Timolati F., Suter T.M., Zuppinger C. Effects of doxorubicin cancer therapy on autophagy and the ubiquitin-proteasome system in long-term cultured adult rat cardiomyocytes. Cell Tissue Res 2012, 350:361-372.
-
(2012)
Cell Tissue Res
, vol.350
, pp. 361-372
-
-
Dimitrakis, P.1
Romay-Ogando, M.I.2
Timolati, F.3
Suter, T.M.4
Zuppinger, C.5
-
20
-
-
84869452725
-
Prior starvation mitigates acute doxorubicin cardiotoxicity through restoration of autophagy in affected cardiomyocytes
-
Kawaguchi T., Takemura G., Kanamori H., Takeyama T., Watanabe T., Morishita K., et al. Prior starvation mitigates acute doxorubicin cardiotoxicity through restoration of autophagy in affected cardiomyocytes. Cardiovasc Res 2012, 96:456-465.
-
(2012)
Cardiovasc Res
, vol.96
, pp. 456-465
-
-
Kawaguchi, T.1
Takemura, G.2
Kanamori, H.3
Takeyama, T.4
Watanabe, T.5
Morishita, K.6
-
21
-
-
84871718306
-
Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity
-
Sishi B.J., Loos B., van Rooyen J., Engelbrecht A.M. Autophagy upregulation promotes survival and attenuates doxorubicin-induced cardiotoxicity. Biochem Pharmacol 2012, 85:124-134.
-
(2012)
Biochem Pharmacol
, vol.85
, pp. 124-134
-
-
Sishi, B.J.1
Loos, B.2
van Rooyen, J.3
Engelbrecht, A.M.4
-
22
-
-
33748561863
-
New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics
-
Tokarska-Schlattner M., Zaugg M., Zuppinger C., Wallimann T., Schlattner U. New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics. J Mol Cell Cardiol 2006, 41:389-405.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 389-405
-
-
Tokarska-Schlattner, M.1
Zaugg, M.2
Zuppinger, C.3
Wallimann, T.4
Schlattner, U.5
-
23
-
-
34548299678
-
Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis
-
Wallace K.B. Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis. Cardiovasc Toxicol 2007, 7:101-107.
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 101-107
-
-
Wallace, K.B.1
-
24
-
-
59449085388
-
Energy metabolism in heart failure and remodelling
-
Ingwall J.S. Energy metabolism in heart failure and remodelling. Cardiovasc Res 2009, 81:412-419.
-
(2009)
Cardiovasc Res
, vol.81
, pp. 412-419
-
-
Ingwall, J.S.1
-
25
-
-
33947239659
-
The failing heart-an engine out of fuel
-
Neubauer S. The failing heart-an engine out of fuel. N Engl J Med 2007, 356:1140-1151.
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
26
-
-
79957937246
-
Bioenergetics of the failing heart
-
Ventura-Clapier R., Garnier A., Veksler V., Joubert F. Bioenergetics of the failing heart. Biochim Biophys Acta 2011, 1813:1360-1372.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1360-1372
-
-
Ventura-Clapier, R.1
Garnier, A.2
Veksler, V.3
Joubert, F.4
-
27
-
-
77950020340
-
Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy
-
Carvalho R.A., Sousa R.P., Cadete V.J., Lopaschuk G.D., Palmeira C.M., Bjork J.A., et al. Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy. Toxicology 2010, 270:92-98.
-
(2010)
Toxicology
, vol.270
, pp. 92-98
-
-
Carvalho, R.A.1
Sousa, R.P.2
Cadete, V.J.3
Lopaschuk, G.D.4
Palmeira, C.M.5
Bjork, J.A.6
-
28
-
-
84867608210
-
Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on Nrf2 and mitochondrial biogenesis pathways
-
Jirkovsky E., Popelova O., Krivakova-Stankova P., Vavrova A., Hroch M., Haskova P., et al. Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on Nrf2 and mitochondrial biogenesis pathways. J Pharmacol Exp Ther 2012, 343:468-478.
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 468-478
-
-
Jirkovsky, E.1
Popelova, O.2
Krivakova-Stankova, P.3
Vavrova, A.4
Hroch, M.5
Haskova, P.6
-
29
-
-
35549010278
-
Reduced creatine-stimulated respiration in doxorubicin challenged mitochondria: particular sensitivity of the heart
-
Tokarska-Schlattner M., Dolder M., Gerber I., Speer O., Wallimann T., Schlattner U. Reduced creatine-stimulated respiration in doxorubicin challenged mitochondria: particular sensitivity of the heart. Biochim Biophys Acta 2007, 1767:1276-1284.
-
(2007)
Biochim Biophys Acta
, vol.1767
, pp. 1276-1284
-
-
Tokarska-Schlattner, M.1
Dolder, M.2
Gerber, I.3
Speer, O.4
Wallimann, T.5
Schlattner, U.6
-
30
-
-
79955661144
-
Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death
-
Kuznetsov A.V., Margreiter R., Amberger A., Saks V., Grimm M. Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death. Biochim Biophys Acta 2011, 1813:1144-1152.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1144-1152
-
-
Kuznetsov, A.V.1
Margreiter, R.2
Amberger, A.3
Saks, V.4
Grimm, M.5
-
31
-
-
77956437166
-
Respiratory chain deficiency precedes the disrupted calcium homeostasis in chronic doxorubicin cardiomyopathy
-
Lebrecht D., Kirschner J., Geist A., Haberstroh J., Walker U.A. Respiratory chain deficiency precedes the disrupted calcium homeostasis in chronic doxorubicin cardiomyopathy. Cardiovasc Pathol 2010, 19:e167-e174.
-
(2010)
Cardiovasc Pathol
, vol.19
-
-
Lebrecht, D.1
Kirschner, J.2
Geist, A.3
Haberstroh, J.4
Walker, U.A.5
-
32
-
-
84867722747
-
Physiological roles of the permeability transition pore
-
Brenner C., Moulin M. Physiological roles of the permeability transition pore. Circ Res 2012, 111:1237-1247.
-
(2012)
Circ Res
, vol.111
, pp. 1237-1247
-
-
Brenner, C.1
Moulin, M.2
-
33
-
-
78650005068
-
Doxorubicin induces mitochondrial permeability transition and contractile dysfunction in the human myocardium
-
Montaigne D., Marechal X., Preau S., Baccouch R., Modine T., Fayad G., et al. Doxorubicin induces mitochondrial permeability transition and contractile dysfunction in the human myocardium. Mitochondrion 2011, 11:22-26.
-
(2011)
Mitochondrion
, vol.11
, pp. 22-26
-
-
Montaigne, D.1
Marechal, X.2
Preau, S.3
Baccouch, R.4
Modine, T.5
Fayad, G.6
-
34
-
-
77949817711
-
AMPK and SIRT1: a long-standing partnership?
-
Ruderman N.B., Xu X.J., Nelson L., Cacicedo J.M., Saha A.K., Lan Y. AMPK and SIRT1: a long-standing partnership?. Am J Physiol Endocrinol Metab 2010, 298:E751-E760.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Ruderman, N.B.1
Xu, X.J.2
Nelson, L.3
Cacicedo, J.M.4
Saha, A.K.5
Lan, Y.6
-
35
-
-
46749125376
-
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha
-
Ventura-Clapier R., Garnier A., Veksler V. Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha. Cardiovasc Res 2008, 79:208-217.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 208-217
-
-
Ventura-Clapier, R.1
Garnier, A.2
Veksler, V.3
-
36
-
-
84863281299
-
Inhibition of AMP-activated protein kinase alpha (AMPKalpha) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1
-
Wang S., Song P., Zou M.H. Inhibition of AMP-activated protein kinase alpha (AMPKalpha) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1. J Biol Chem 2012, 287:8001-8012.
-
(2012)
J Biol Chem
, vol.287
, pp. 8001-8012
-
-
Wang, S.1
Song, P.2
Zou, M.H.3
-
37
-
-
21644455865
-
Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply
-
Tokarska-Schlattner M., Zaugg M., da Silva R., Lucchinetti E., Schaub M.C., Wallimann T., et al. Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply. Am J Physiol Heart Circ Physiol 2005, 289:H37-H47.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Tokarska-Schlattner, M.1
Zaugg, M.2
da Silva, R.3
Lucchinetti, E.4
Schaub, M.C.5
Wallimann, T.6
-
38
-
-
84871696392
-
Inhibition of AMPK signaling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress
-
Gratia S., Kay L., Potenza L., Seffouh A., Novel-Chate V., Schnebelen C., et al. Inhibition of AMPK signaling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress. Cardiovasc Res 2012, 95:290-299.
-
(2012)
Cardiovasc Res
, vol.95
, pp. 290-299
-
-
Gratia, S.1
Kay, L.2
Potenza, L.3
Seffouh, A.4
Novel-Chate, V.5
Schnebelen, C.6
-
39
-
-
67349234999
-
Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway
-
Danz E.D., Skramsted J., Henry N., Bennett J.A., Keller R.S. Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. Free Radic Biol Med 2009, 46:1589-1597.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1589-1597
-
-
Danz, E.D.1
Skramsted, J.2
Henry, N.3
Bennett, J.A.4
Keller, R.S.5
-
40
-
-
78751554136
-
Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation
-
Konishi M., Haraguchi G., Ohigashi H., Ishihara T., Saito K., Nakano Y., et al. Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation. Cardiovasc Res 2010, 89:309-319.
-
(2010)
Cardiovasc Res
, vol.89
, pp. 309-319
-
-
Konishi, M.1
Haraguchi, G.2
Ohigashi, H.3
Ishihara, T.4
Saito, K.5
Nakano, Y.6
-
41
-
-
0023710225
-
Ultrastructural morphometric analysis of endomyocardial biopsies. Idiopathic dilated cardiomyopathy, anthracycline cardiotoxicity, and normal myocardium
-
Rowan R.A., Masek M.A., Billingham M.E. Ultrastructural morphometric analysis of endomyocardial biopsies. Idiopathic dilated cardiomyopathy, anthracycline cardiotoxicity, and normal myocardium. Am J Cardiovasc Pathol 1988, 2(2):137-144.
-
(1988)
Am J Cardiovasc Pathol
, vol.2
, Issue.2
, pp. 137-144
-
-
Rowan, R.A.1
Masek, M.A.2
Billingham, M.E.3
-
42
-
-
84871674588
-
MTOR: good, bad, or ugly?
-
Zhang Y., Zhang T., Cao C.M., Xiao R.P. mTOR: good, bad, or ugly?. Cardiovasc Res 2012, 95(3):261-262.
-
(2012)
Cardiovasc Res
, vol.95
, Issue.3
, pp. 261-262
-
-
Zhang, Y.1
Zhang, T.2
Cao, C.M.3
Xiao, R.P.4
-
43
-
-
0043237846
-
Doxorubicin-induced cardiac mitochondrionopathy
-
Wallace K.B. Doxorubicin-induced cardiac mitochondrionopathy. Pharmacol Toxicol 2003, 93:105-115.
-
(2003)
Pharmacol Toxicol
, vol.93
, pp. 105-115
-
-
Wallace, K.B.1
-
44
-
-
0035576817
-
Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy
-
Minotti G., Ronchi R., Salvatorelli E., Menna P., Cairo G. Doxorubicin irreversibly inactivates iron regulatory proteins 1 and 2 in cardiomyocytes: evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy. Cancer Res 2001, 61(23):8422-8428.
-
(2001)
Cancer Res
, vol.61
, Issue.23
, pp. 8422-8428
-
-
Minotti, G.1
Ronchi, R.2
Salvatorelli, E.3
Menna, P.4
Cairo, G.5
-
45
-
-
34548403111
-
Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin
-
Neilan T.G., Blake S.L., Ichinose F., Raher M.J., Buys E.S., Jassal D.S., et al. Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin. Circulation 2007, 116:506-514.
-
(2007)
Circulation
, vol.116
, pp. 506-514
-
-
Neilan, T.G.1
Blake, S.L.2
Ichinose, F.3
Raher, M.J.4
Buys, E.S.5
Jassal, D.S.6
-
46
-
-
34548361626
-
Role of mtDNA lesions in anthracycline cardiotoxicity
-
Lebrecht D., Walker U.A. Role of mtDNA lesions in anthracycline cardiotoxicity. Cardiovasc Toxicol 2007, 7(2):108-113.
-
(2007)
Cardiovasc Toxicol
, vol.7
, Issue.2
, pp. 108-113
-
-
Lebrecht, D.1
Walker, U.A.2
-
47
-
-
33847096349
-
Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management
-
Takemura G., Fujiwara H. Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. Prog Cardiovasc Dis 2007, 49:330-352.
-
(2007)
Prog Cardiovasc Dis
, vol.49
, pp. 330-352
-
-
Takemura, G.1
Fujiwara, H.2
-
48
-
-
62449233690
-
Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice
-
Niu J., Azfer A., Wang K., Wang X., Kolattukudy P.E. Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice. J Pharmacol Exp Ther 2009, 328(3):740-748.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, Issue.3
, pp. 740-748
-
-
Niu, J.1
Azfer, A.2
Wang, K.3
Wang, X.4
Kolattukudy, P.E.5
-
49
-
-
22544466964
-
Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium
-
Kalivendi S.V., Konorev E.A., Cunningham S., Vanamala S.K., Kaji E.H., Joseph J., et al. Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. Biochem J 2005, 389:527-539.
-
(2005)
Biochem J
, vol.389
, pp. 527-539
-
-
Kalivendi, S.V.1
Konorev, E.A.2
Cunningham, S.3
Vanamala, S.K.4
Kaji, E.H.5
Joseph, J.6
-
50
-
-
33847753121
-
Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes
-
Ito T., Fujio Y., Takahashi K., Azuma J. Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes. J Biol Chem 2007, 282(2):1152-1160.
-
(2007)
J Biol Chem
, vol.282
, Issue.2
, pp. 1152-1160
-
-
Ito, T.1
Fujio, Y.2
Takahashi, K.3
Azuma, J.4
-
51
-
-
33845666247
-
Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation
-
Kim D.S., Woo E.R., Chae S.W., Ha K.C., Lee G.H., Hong S.T., et al. Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation. Life Sci 2007, 80(4):314-323.
-
(2007)
Life Sci
, vol.80
, Issue.4
, pp. 314-323
-
-
Kim, D.S.1
Woo, E.R.2
Chae, S.W.3
Ha, K.C.4
Lee, G.H.5
Hong, S.T.6
-
52
-
-
33751258581
-
Protective effects of pyrrolidine dithiocarbamate on myocardium apoptosis induced by adriamycin in rats
-
Li H., Gu H., Sun B. Protective effects of pyrrolidine dithiocarbamate on myocardium apoptosis induced by adriamycin in rats. Int J Cardiol 2007, 114(2):159-165.
-
(2007)
Int J Cardiol
, vol.114
, Issue.2
, pp. 159-165
-
-
Li, H.1
Gu, H.2
Sun, B.3
-
53
-
-
77955277457
-
Elevation of cyclic AMP causes an imbalance between NF-kappaB and p53 in NALM-6 cells treated by doxorubicin
-
Safa M., Zand H., Mousavizadeh K., Kazemi A., Bakhshayesh M., Hayat P. Elevation of cyclic AMP causes an imbalance between NF-kappaB and p53 in NALM-6 cells treated by doxorubicin. FEBS Lett 2010, 584(15):3492-3498.
-
(2010)
FEBS Lett
, vol.584
, Issue.15
, pp. 3492-3498
-
-
Safa, M.1
Zand, H.2
Mousavizadeh, K.3
Kazemi, A.4
Bakhshayesh, M.5
Hayat, P.6
-
54
-
-
0037216823
-
Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytes
-
Nitobe J., Yamaguchi S., Okuyama M., Nozaki N., Sata M., Miyamoto T., et al. Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytes. Cardiovasc Res 2003, 57(1):119-128.
-
(2003)
Cardiovasc Res
, vol.57
, Issue.1
, pp. 119-128
-
-
Nitobe, J.1
Yamaguchi, S.2
Okuyama, M.3
Nozaki, N.4
Sata, M.5
Miyamoto, T.6
-
55
-
-
8144229686
-
Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice
-
Nozaki N., Shishido T., Takeishi Y., Kubota I. Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice. Circulation 2004, 110(18):2869-2874.
-
(2004)
Circulation
, vol.110
, Issue.18
, pp. 2869-2874
-
-
Nozaki, N.1
Shishido, T.2
Takeishi, Y.3
Kubota, I.4
-
56
-
-
38049155818
-
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis
-
Deniaud A., Sharaf el dein O., Maillier E., Poncet D., Kroemer G., Lemaire C., et al. Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis. Oncogene 2008, 27(3):285-299.
-
(2008)
Oncogene
, vol.27
, Issue.3
, pp. 285-299
-
-
Deniaud, A.1
Sharaf el dein, O.2
Maillier, E.3
Poncet, D.4
Kroemer, G.5
Lemaire, C.6
-
57
-
-
33748420367
-
DNA damage is an early event in doxorubicin-induced cardiac myocyte death
-
L'Ecuyer T., Sanjeev S., Thomas R., Novak R., Das L., Campbell W., et al. DNA damage is an early event in doxorubicin-induced cardiac myocyte death. Am J Physiol Heart Circ Physiol 2006, 291(3):H1273-H1280.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
, Issue.3
-
-
L'Ecuyer, T.1
Sanjeev, S.2
Thomas, R.3
Novak, R.4
Das, L.5
Campbell, W.6
-
58
-
-
57049095435
-
ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes
-
Liu J., Mao W., Ding B., Liang C.S. ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes. Am J Physiol Heart Circ Physiol 2008, 295:H1956-H1965.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Liu, J.1
Mao, W.2
Ding, B.3
Liang, C.S.4
-
59
-
-
20144366284
-
Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice
-
Shizukuda Y., Matoba S., Mian O.Y., Nguyen T., Hwang P.M. Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice. Mol Cell Biochem 2005, 273:25-32.
-
(2005)
Mol Cell Biochem
, vol.273
, pp. 25-32
-
-
Shizukuda, Y.1
Matoba, S.2
Mian, O.Y.3
Nguyen, T.4
Hwang, P.M.5
-
60
-
-
59049091824
-
Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway
-
Zhu W., Soonpaa M.H., Chen H., Shen W., Payne R.M., Liechty E.A., et al. Acute doxorubicin cardiotoxicity is associated with p53-induced inhibition of the mammalian target of rapamycin pathway. Circulation 2009, 119(1):99-106.
-
(2009)
Circulation
, vol.119
, Issue.1
, pp. 99-106
-
-
Zhu, W.1
Soonpaa, M.H.2
Chen, H.3
Shen, W.4
Payne, R.M.5
Liechty, E.A.6
-
61
-
-
79960858307
-
Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes
-
Feridooni T., Hotchkiss A., Remley-Carr S., Saga Y., Pasumarthi K.B. Cardiomyocyte specific ablation of p53 is not sufficient to block doxorubicin induced cardiac fibrosis and associated cytoskeletal changes. PLoS One 2011, 6(7):e22801.
-
(2011)
PLoS One
, vol.6
, Issue.7
-
-
Feridooni, T.1
Hotchkiss, A.2
Remley-Carr, S.3
Saga, Y.4
Pasumarthi, K.B.5
-
62
-
-
34249029995
-
Evidence for p53 as guardian of the cardiomyocyte mitochondrial genome following acute adriamycin treatment
-
Nithipongvanitch R., Ittarat W., Velez J.M., Zhao R., St Clair D.K., Oberley T.D. Evidence for p53 as guardian of the cardiomyocyte mitochondrial genome following acute adriamycin treatment. J Histochem Cytochem 2007, 55:629-639.
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 629-639
-
-
Nithipongvanitch, R.1
Ittarat, W.2
Velez, J.M.3
Zhao, R.4
St Clair, D.K.5
Oberley, T.D.6
-
63
-
-
33746379949
-
Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells
-
Shacka J.J., Sahawneh M.A., Gonzalez J.D., Ye Y.Z., D'Alessandro T.L., Estévez A.G. Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells. Cell Death Differ 2006, 13(9):1506-1514.
-
(2006)
Cell Death Differ
, vol.13
, Issue.9
, pp. 1506-1514
-
-
Shacka, J.J.1
Sahawneh, M.A.2
Gonzalez, J.D.3
Ye, Y.Z.4
D'Alessandro, T.L.5
Estévez, A.G.6
-
64
-
-
2342619408
-
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity
-
Aries A., Paradis P., Lefebvre C., Schwartz R.J., Nemer M. Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity. Proc Natl Acad Sci U S A 2004, 101(18):6975-6980.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.18
, pp. 6975-6980
-
-
Aries, A.1
Paradis, P.2
Lefebvre, C.3
Schwartz, R.J.4
Nemer, M.5
-
65
-
-
36849079020
-
The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy
-
Suliman H.B., Carraway M.S., Ali A.S., Reynolds C.M., Welty-Wolf K.E., Piantadosi C.A. The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy. J Clin Invest 2007, 117(12):3730-3741.
-
(2007)
J Clin Invest
, vol.117
, Issue.12
, pp. 3730-3741
-
-
Suliman, H.B.1
Carraway, M.S.2
Ali, A.S.3
Reynolds, C.M.4
Welty-Wolf, K.E.5
Piantadosi, C.A.6
-
66
-
-
79952833333
-
Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart
-
Park A.M., Nagase H., Liu L., Vinod Kumar S., Szwergold N., Wong C.M., et al. Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart. Cardiovasc Res 2011, 90(1):97-104.
-
(2011)
Cardiovasc Res
, vol.90
, Issue.1
, pp. 97-104
-
-
Park, A.M.1
Nagase, H.2
Liu, L.3
Vinod Kumar, S.4
Szwergold, N.5
Wong, C.M.6
-
67
-
-
10744230132
-
Expression of p300 protects cardiac myocytes from apoptosis in vivo
-
Kawamura T., Hasegawa K., Morimoto T., Iwai-Kanai E., Miyamoto S., Kawase Y., et al. Expression of p300 protects cardiac myocytes from apoptosis in vivo. Biochem Biophys Res Commun 2004, 315(3):733-738.
-
(2004)
Biochem Biophys Res Commun
, vol.315
, Issue.3
, pp. 733-738
-
-
Kawamura, T.1
Hasegawa, K.2
Morimoto, T.3
Iwai-Kanai, E.4
Miyamoto, S.5
Kawase, Y.6
-
68
-
-
15044342095
-
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells
-
Poizat C., Puri P.L., Bai Y., Kedes L. Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol Cell Biol 2005, 25(7):2673-2687.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.7
, pp. 2673-2687
-
-
Poizat, C.1
Puri, P.L.2
Bai, Y.3
Kedes, L.4
-
69
-
-
20044392926
-
ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance
-
Mercier I., Vuolo M., Madan R., Xue X., Levalley A.J., Ashton A.W., et al. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance. Cell Death Differ 2005, 12(6):682-686.
-
(2005)
Cell Death Differ
, vol.12
, Issue.6
, pp. 682-686
-
-
Mercier, I.1
Vuolo, M.2
Madan, R.3
Xue, X.4
Levalley, A.J.5
Ashton, A.W.6
-
70
-
-
64149124058
-
ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity
-
An J., Li P., Li J., Dietz R., Donath S. ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity. J Mol Med (Berl) 2009, 87(4):401-410.
-
(2009)
J Mol Med (Berl)
, vol.87
, Issue.4
, pp. 401-410
-
-
An, J.1
Li, P.2
Li, J.3
Dietz, R.4
Donath, S.5
-
71
-
-
58149343451
-
Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity
-
Fan G.C., Zhou X., Wang X., Song G., Qian J., Nicolaou P., et al. Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity. Circ Res 2008, 103(11):1270-1279.
-
(2008)
Circ Res
, vol.103
, Issue.11
, pp. 1270-1279
-
-
Fan, G.C.1
Zhou, X.2
Wang, X.3
Song, G.4
Qian, J.5
Nicolaou, P.6
-
72
-
-
58149328569
-
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
-
Piantadosi C.A., Carraway M.S., Babiker A., Suliman H.B. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ Res 2008, 103(11):1232-1240.
-
(2008)
Circ Res
, vol.103
, Issue.11
, pp. 1232-1240
-
-
Piantadosi, C.A.1
Carraway, M.S.2
Babiker, A.3
Suliman, H.B.4
-
73
-
-
77955906955
-
Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?
-
Sawyer D.B., Peng X., Chen B., Pentassuglia L., Lim C.C. Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?. Prog Cardiovasc Dis 2010, 53(2):105-113.
-
(2010)
Prog Cardiovasc Dis
, vol.53
, Issue.2
, pp. 105-113
-
-
Sawyer, D.B.1
Peng, X.2
Chen, B.3
Pentassuglia, L.4
Lim, C.C.5
-
74
-
-
77957132594
-
Modulation of doxorubicin-induced cardiac dysfunction in dominant-negative p38α mitogen-activated protein kinase mice
-
Thandavarayan R.A., Watanabe K., Sari F.R., Ma M., Lakshmanan A.P., Giridharan V.V., et al. Modulation of doxorubicin-induced cardiac dysfunction in dominant-negative p38α mitogen-activated protein kinase mice. Free Radic Biol Med 2010, 49(9):1422-1431.
-
(2010)
Free Radic Biol Med
, vol.49
, Issue.9
, pp. 1422-1431
-
-
Thandavarayan, R.A.1
Watanabe, K.2
Sari, F.R.3
Ma, M.4
Lakshmanan, A.P.5
Giridharan, V.V.6
-
75
-
-
34147093748
-
Rho kinase in the regulation of cell death and survival
-
Shi J., Wei L. Rho kinase in the regulation of cell death and survival. Arch Immunol Ther Exp 2007, 55:61-75.
-
(2007)
Arch Immunol Ther Exp
, vol.55
, pp. 61-75
-
-
Shi, J.1
Wei, L.2
-
76
-
-
34848902937
-
2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure
-
2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. J Clin Invest 2007, 117(9):2431-2444.
-
(2007)
J Clin Invest
, vol.117
, Issue.9
, pp. 2431-2444
-
-
Nakayama, H.1
Chen, X.2
Baines, C.P.3
Klevitsky, R.4
Zhang, X.5
Zhang, H.6
-
77
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa T., Shimizu S., Watanabe T., Yamaguchi O., Otsu K., Yamagata H., et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005, 434(7033):652-658.
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
-
78
-
-
58349097915
-
Pretreatment with statin attenuates the cardiotoxicity of doxorubicin in mice
-
Riad A., Bien S., Westermann D., Becher P.M., Loya K., Landmesser U., et al. Pretreatment with statin attenuates the cardiotoxicity of doxorubicin in mice. Cancer Res 2009, 69:695-699.
-
(2009)
Cancer Res
, vol.69
, pp. 695-699
-
-
Riad, A.1
Bien, S.2
Westermann, D.3
Becher, P.M.4
Loya, K.5
Landmesser, U.6
-
79
-
-
33847029183
-
Necrotic death without mitochondrial dysfunction-delayed death of cardiac myocytes following oxidative stress
-
Casey T.M., Arthur P.G., Bogoyevitch M.A. Necrotic death without mitochondrial dysfunction-delayed death of cardiac myocytes following oxidative stress. Biochim Biophys Acta 2007, 1773:342-351.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 342-351
-
-
Casey, T.M.1
Arthur, P.G.2
Bogoyevitch, M.A.3
-
80
-
-
1542349778
-
Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes
-
Lim C.C., Zuppinger C., Guo X., Kuster G.M., Helmes M., Eppenberger H.M., et al. Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes. J Biol Chem 2004, 279:8290-8299.
-
(2004)
J Biol Chem
, vol.279
, pp. 8290-8299
-
-
Lim, C.C.1
Zuppinger, C.2
Guo, X.3
Kuster, G.M.4
Helmes, M.5
Eppenberger, H.M.6
-
81
-
-
41249092847
-
Ultrastructural definition of apoptosis in heart failure
-
Arbustini E., Brega A., Narula J. Ultrastructural definition of apoptosis in heart failure. Heart Fail Rev 2008, 13(2):121-135.
-
(2008)
Heart Fail Rev
, vol.13
, Issue.2
, pp. 121-135
-
-
Arbustini, E.1
Brega, A.2
Narula, J.3
-
82
-
-
2542461224
-
Glutathione S-transferase overexpression protects against anthracycline-induced H9C2 cell death
-
L'Ecuyer T., Allebban Z., Thomas R., Vander Heide R. Glutathione S-transferase overexpression protects against anthracycline-induced H9C2 cell death. Am J Physiol Heart Circ Physiol 2004, 286(6):H2057-H2064.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
, Issue.6
-
-
L'Ecuyer, T.1
Allebban, Z.2
Thomas, R.3
Vander Heide, R.4
-
83
-
-
72549092827
-
Activation of the ubiquitin proteasome system in doxorubicin cardiomyopathy
-
Ranek M.J., Wang X. Activation of the ubiquitin proteasome system in doxorubicin cardiomyopathy. Curr Hypertens Rep 2009, 11(6):389-395.
-
(2009)
Curr Hypertens Rep
, vol.11
, Issue.6
, pp. 389-395
-
-
Ranek, M.J.1
Wang, X.2
-
84
-
-
69349085605
-
Autophagy in the cardiovascular system
-
De Meyer G.R., Martinet W. Autophagy in the cardiovascular system. Biochim Biophys Acta 2009, 1793(9):1485-1495.
-
(2009)
Biochim Biophys Acta
, vol.1793
, Issue.9
, pp. 1485-1495
-
-
De Meyer, G.R.1
Martinet, W.2
-
85
-
-
64149124827
-
Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure
-
Lu L., Wu W., Yan J., Li X., Yu H., Yu X. Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure. Int J Cardiol 2009, 134(1):82-90.
-
(2009)
Int J Cardiol
, vol.134
, Issue.1
, pp. 82-90
-
-
Lu, L.1
Wu, W.2
Yan, J.3
Li, X.4
Yu, H.5
Yu, X.6
-
86
-
-
48249092267
-
Bcl-2 family members: dual regulators of apoptosis and autophagy
-
Levine B., Sinha S., Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2001, 4:600-606.
-
(2001)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
87
-
-
34548188741
-
Self-eating and self-killing: crosstalk between autophagy and apoptosis
-
Maiuri M.C., Zalckvar E., Kimchi A., Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007, 8(9):741-752.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.9
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
88
-
-
58149380360
-
PARP-1 is involved in autophagy induced by DNA damage
-
Muñoz-Gámez J.A., Rodríguez-Vargas J.M., Quiles-Pérez R., Aguilar-Quesada R., Martín-Oliva D., de Murcia G., et al. PARP-1 is involved in autophagy induced by DNA damage. Autophagy 2009, 5(1):61-74.
-
(2009)
Autophagy
, vol.5
, Issue.1
, pp. 61-74
-
-
Muñoz-Gámez, J.A.1
Rodríguez-Vargas, J.M.2
Quiles-Pérez, R.3
Aguilar-Quesada, R.4
Martín-Oliva, D.5
de Murcia, G.6
-
89
-
-
84880528869
-
Doxorubicin-induced markers of myocardial autophagic signaling in sedentary and exercise trained animals
-
Smuder A.J., Kavazis A.N., Min K., Powers S.K. Doxorubicin-induced markers of myocardial autophagic signaling in sedentary and exercise trained animals. J Appl Physiol 2013, 115(2):176-185.
-
(2013)
J Appl Physiol
, vol.115
, Issue.2
, pp. 176-185
-
-
Smuder, A.J.1
Kavazis, A.N.2
Min, K.3
Powers, S.K.4
-
90
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
Force T., Krause D.S., Van Etten R.A. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007, 7:332-344.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
91
-
-
74049164266
-
The vulnerability of the heart as a pluricellular paracrine organ: lessons from unexpected triggers of heart failure in targeted ErbB2 anticancer therapy
-
De Keulenaer G.W., Doggen K., Lemmens K. The vulnerability of the heart as a pluricellular paracrine organ: lessons from unexpected triggers of heart failure in targeted ErbB2 anticancer therapy. Circ Res 2010, 106:35-46.
-
(2010)
Circ Res
, vol.106
, pp. 35-46
-
-
De Keulenaer, G.W.1
Doggen, K.2
Lemmens, K.3
-
92
-
-
77955891306
-
Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
-
Horie T., Ono K., Nishi H., Nagao K., Kinoshita M., Watanabe S., et al. Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway. Cardiovasc Res 2010, 87(4):656-664.
-
(2010)
Cardiovasc Res
, vol.87
, Issue.4
, pp. 656-664
-
-
Horie, T.1
Ono, K.2
Nishi, H.3
Nagao, K.4
Kinoshita, M.5
Watanabe, S.6
-
93
-
-
43549098268
-
Calcium cycling and signaling in cardiac myocytes
-
Bers D.M. Calcium cycling and signaling in cardiac myocytes. Ann Rev Physiol 2008, 70:23-49.
-
(2008)
Ann Rev Physiol
, vol.70
, pp. 23-49
-
-
Bers, D.M.1
-
94
-
-
77952098930
-
-
Lippincott Williams and Wilkins, a Wolters Kluwer business, Philadelphia, USA
-
Halperin E.C., Perez C.A., Brady L.W. Principles and practice of radiation oncology 2004, 2368. Lippincott Williams and Wilkins, a Wolters Kluwer business, Philadelphia, USA. 5th ed.
-
(2004)
Principles and practice of radiation oncology
, pp. 2368
-
-
Halperin, E.C.1
Perez, C.A.2
Brady, L.W.3
-
95
-
-
33745198418
-
Redox regulation of cardiac calcium channels and transporters
-
Zima A.V., Blatter L.A. Redox regulation of cardiac calcium channels and transporters. Cardiovasc Res 2006, 71:310-321.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 310-321
-
-
Zima, A.V.1
Blatter, L.A.2
-
97
-
-
0037023247
-
Doxorubicin directly binds to the cardiac-type ryanodine receptor
-
Saeki K., Obi I., Ogiku N., Shigekawa M., Imagawa T., Matsumoto T. Doxorubicin directly binds to the cardiac-type ryanodine receptor. Life Sci 2002, 70:2377-2389.
-
(2002)
Life Sci
, vol.70
, pp. 2377-2389
-
-
Saeki, K.1
Obi, I.2
Ogiku, N.3
Shigekawa, M.4
Imagawa, T.5
Matsumoto, T.6
-
98
-
-
11344254464
-
Interaction between cardiac calsequestrin and drugs with known cardiotoxicity
-
Park I.Y., Kim E.J., Park H., Fields K., Dunker A.K., Kang C. Interaction between cardiac calsequestrin and drugs with known cardiotoxicity. Molecular Pharmacol 2005, 67:97-104.
-
(2005)
Molecular Pharmacol
, vol.67
, pp. 97-104
-
-
Park, I.Y.1
Kim, E.J.2
Park, H.3
Fields, K.4
Dunker, A.K.5
Kang, C.6
-
99
-
-
20944438956
-
Investigations of calsequestrin as a target for anthracyclines: comparison of functional effects of daunorubicin, daunorubicinol, and trifluoperazine
-
Charlier H.A., Olson R.D., Thornock C.M., Mercer W.K., Olson D.R., Broyles T.S. Investigations of calsequestrin as a target for anthracyclines: comparison of functional effects of daunorubicin, daunorubicinol, and trifluoperazine. Mol Pharmacol 2005, 67:1505-1512.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1505-1512
-
-
Charlier, H.A.1
Olson, R.D.2
Thornock, C.M.3
Mercer, W.K.4
Olson, D.R.5
Broyles, T.S.6
-
100
-
-
80051982074
-
Multiple actions of the anthracycline daunorubicin on cardiac ryanodine receptors
-
Hanna A.D., Janczura M., Cho E., Dulhunty A.F., Beard N.A. Multiple actions of the anthracycline daunorubicin on cardiac ryanodine receptors. Mol Pharmacol 2011, 80:538-549.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 538-549
-
-
Hanna, A.D.1
Janczura, M.2
Cho, E.3
Dulhunty, A.F.4
Beard, N.A.5
-
103
-
-
0035816479
-
Effects of doxorubicinol on excitation-contraction coupling in guinea pig ventricular myocytes
-
Wang G.X., Wang Y.X., Zhou X.B., Korth M. Effects of doxorubicinol on excitation-contraction coupling in guinea pig ventricular myocytes. Eur J Pharmacol 2001, 423:99-107.
-
(2001)
Eur J Pharmacol
, vol.423
, pp. 99-107
-
-
Wang, G.X.1
Wang, Y.X.2
Zhou, X.B.3
Korth, M.4
-
104
-
-
20344398645
-
Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism
-
Wold L.E., Aberle N.S., Ren J. Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism. Cancer Detect Prev 2005, 29:294-299.
-
(2005)
Cancer Detect Prev
, vol.29
, pp. 294-299
-
-
Wold, L.E.1
Aberle, N.S.2
Ren, J.3
-
105
-
-
80053259051
-
CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes
-
Sag C.M., Kohler A.C., Anderson M.E., Backs J., Maier L.S. CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes. J Mol Cell Cardiol 2011, 51:749-759.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 749-759
-
-
Sag, C.M.1
Kohler, A.C.2
Anderson, M.E.3
Backs, J.4
Maier, L.S.5
-
106
-
-
0013228058
-
Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol
-
Olson R.D., Mushlin P.S., Brenner D.E., Fleischer S., Cusack B.J., Chang B.K., et al. Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol. Proc Natl Acad Sci U S A 1988, 85:3585-3589.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 3585-3589
-
-
Olson, R.D.1
Mushlin, P.S.2
Brenner, D.E.3
Fleischer, S.4
Cusack, B.J.5
Chang, B.K.6
-
107
-
-
0025139123
-
Thiol oxidation and inhibition of Ca-ATPase by adriamycin in rabbit heart microsomes
-
Vile G., Winterbourn C. Thiol oxidation and inhibition of Ca-ATPase by adriamycin in rabbit heart microsomes. Biochem Pharmacol 1990, 39:769-774.
-
(1990)
Biochem Pharmacol
, vol.39
, pp. 769-774
-
-
Vile, G.1
Winterbourn, C.2
-
110
-
-
0036293197
-
Doxorubicin C-13 deoxydoxorubicin effects on ryanodine receptor gene expression
-
Gambliel H.A., Burke B.E., Cusack B.J., Walsh G.M., Zhang Y.L., Mushlin P.S., et al. Doxorubicin C-13 deoxydoxorubicin effects on ryanodine receptor gene expression. Biochem Biophys Res Commun 2002, 291:433-438.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 433-438
-
-
Gambliel, H.A.1
Burke, B.E.2
Cusack, B.J.3
Walsh, G.M.4
Zhang, Y.L.5
Mushlin, P.S.6
-
111
-
-
84871627956
-
The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms
-
Quốc Lu'o'ng K.V., Nguyễn L.T. The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms. Cancer Manag Res 2012, 4:431-445.
-
(2012)
Cancer Manag Res
, vol.4
, pp. 431-445
-
-
Quốc Lu'o'ng, K.V.1
Nguyễn, L.T.2
-
112
-
-
77953322829
-
Alterations of pre- and postsynaptic noradrenergic signaling in a rat model of adriamycin-induced cardiotoxicity
-
Kenk M., Thackeray J.T., Thorn S.L., Dhami K., Chow B.J., Ascah K.J., et al. Alterations of pre- and postsynaptic noradrenergic signaling in a rat model of adriamycin-induced cardiotoxicity. J Nucl Cardiol 2010, 17(2):254-263.
-
(2010)
J Nucl Cardiol
, vol.17
, Issue.2
, pp. 254-263
-
-
Kenk, M.1
Thackeray, J.T.2
Thorn, S.L.3
Dhami, K.4
Chow, B.J.5
Ascah, K.J.6
-
113
-
-
7444220198
-
Changes in myocardial beta1-adrenergic receptor and stimulatory G-protein gene expression after chronic treatment with doxorubicin in rat
-
Kizaki K., Akatsuka K., Momozaki M., Fujimori Y., Uchide T., Temma K., et al. Changes in myocardial beta1-adrenergic receptor and stimulatory G-protein gene expression after chronic treatment with doxorubicin in rat. J Vet Med Sci 2004, 66(8):989-992.
-
(2004)
J Vet Med Sci
, vol.66
, Issue.8
, pp. 989-992
-
-
Kizaki, K.1
Akatsuka, K.2
Momozaki, M.3
Fujimori, Y.4
Uchide, T.5
Temma, K.6
-
114
-
-
0030899485
-
Abnormal beta-adrenergic transmembrane signaling in rabbits with adriamycin-induced cardiomyopathy
-
Nagami K., Yoshikawa T., Suzuki M., Wainai Y., Anzai T., Handa S. Abnormal beta-adrenergic transmembrane signaling in rabbits with adriamycin-induced cardiomyopathy. Jpn Circ J 1997, 61(3):249-255.
-
(1997)
Jpn Circ J
, vol.61
, Issue.3
, pp. 249-255
-
-
Nagami, K.1
Yoshikawa, T.2
Suzuki, M.3
Wainai, Y.4
Anzai, T.5
Handa, S.6
-
115
-
-
77956233231
-
Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect
-
Koka S., Das A., Zhu S.G., Durrant D., Xi L., Kukreja R.C. Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect. J Pharmacol Exp Ther 2010, 334(3):1023-1030.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, Issue.3
, pp. 1023-1030
-
-
Koka, S.1
Das, A.2
Zhu, S.G.3
Durrant, D.4
Xi, L.5
Kukreja, R.C.6
-
116
-
-
28144434188
-
Differential cardioprotective/cardiotoxic effects mediated by beta-adrenergic receptor subtypes
-
Bernstein D., Fajardo G., Zhao M., Urashima T., Powers J., Berry G., et al. Differential cardioprotective/cardiotoxic effects mediated by beta-adrenergic receptor subtypes. Am J Physiol Heart Circ Physiol 2005, 289(6):H2441-H2449.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
, Issue.6
-
-
Bernstein, D.1
Fajardo, G.2
Zhao, M.3
Urashima, T.4
Powers, J.5
Berry, G.6
-
117
-
-
70349734337
-
Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity
-
Yoshida M., Shiojima I., Ikeda H., Komuro I. Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity. J Mol Cell Cardiol 2009, 47(5):698-705.
-
(2009)
J Mol Cell Cardiol
, vol.47
, Issue.5
, pp. 698-705
-
-
Yoshida, M.1
Shiojima, I.2
Ikeda, H.3
Komuro, I.4
-
118
-
-
80052328841
-
Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity
-
Huelsenbeck J., Henninger C., Schad A., Lackner K.J., Kaina B., Fritz G. Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity. Cell Death Dis 2011, 11(2):e190.
-
(2011)
Cell Death Dis
, vol.11
, Issue.2
-
-
Huelsenbeck, J.1
Henninger, C.2
Schad, A.3
Lackner, K.J.4
Kaina, B.5
Fritz, G.6
-
119
-
-
84869074814
-
Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons
-
Huelsenbeck S.C., Schorr A., Roos W.P., Huelsenbeck J., Henninger C., Kaina B., et al. Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons. J Biol Chem 2012, 287(46):38590-38599.
-
(2012)
J Biol Chem
, vol.287
, Issue.46
, pp. 38590-38599
-
-
Huelsenbeck, S.C.1
Schorr, A.2
Roos, W.P.3
Huelsenbeck, J.4
Henninger, C.5
Kaina, B.6
-
120
-
-
0036830256
-
Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells
-
Grünwald V., DeGraffenried L., Russel D., Friedrichs W.E., Ray R.B., Hidalgo M. Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells. Cancer Res 2002, 62(21):6141-6145.
-
(2002)
Cancer Res
, vol.62
, Issue.21
, pp. 6141-6145
-
-
Grünwald, V.1
DeGraffenried, L.2
Russel, D.3
Friedrichs, W.E.4
Ray, R.B.5
Hidalgo, M.6
-
121
-
-
80053561902
-
Preventive effects of fasudil on adriamycin-induced cardiomyopathy: possible involvement of inhibition of RhoA/ROCK pathway
-
Wang N., Guan P., Zhang J.P., Chang Y.Z., Gu L.J., Hao F.K., et al. Preventive effects of fasudil on adriamycin-induced cardiomyopathy: possible involvement of inhibition of RhoA/ROCK pathway. Food Chem Toxicol 2011, 49(11):2975-2982.
-
(2011)
Food Chem Toxicol
, vol.49
, Issue.11
, pp. 2975-2982
-
-
Wang, N.1
Guan, P.2
Zhang, J.P.3
Chang, Y.Z.4
Gu, L.J.5
Hao, F.K.6
-
122
-
-
54249105822
-
RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells
-
Doublier S., Riganti C., Voena C., Costamagna C., Aldieri E., Pescarmona G., et al. RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells. Mol Cancer Res 2008, 6(10):1607-1620.
-
(2008)
Mol Cancer Res
, vol.6
, Issue.10
, pp. 1607-1620
-
-
Doublier, S.1
Riganti, C.2
Voena, C.3
Costamagna, C.4
Aldieri, E.5
Pescarmona, G.6
-
123
-
-
58149265138
-
Carvedilol as a protector against the cardiotoxicity induced by anthracyclines (doxorubicin)
-
Machado V., Cabral A., Monteiro P., Gonçalves L., Providência L.A. Carvedilol as a protector against the cardiotoxicity induced by anthracyclines (doxorubicin). Rev Port Cardiol 2008, 27(10):1277-1296.
-
(2008)
Rev Port Cardiol
, vol.27
, Issue.10
, pp. 1277-1296
-
-
Machado, V.1
Cabral, A.2
Monteiro, P.3
Gonçalves, L.4
Providência, L.A.5
-
124
-
-
84874637446
-
Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions
-
Potiron V.A., Abderrhamani R., Giang E., Chiavassa S., Di Tomaso E., Maira S.M., et al. Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions. Radiother Oncol 2013, 106(1):138-146.
-
(2013)
Radiother Oncol
, vol.106
, Issue.1
, pp. 138-146
-
-
Potiron, V.A.1
Abderrhamani, R.2
Giang, E.3
Chiavassa, S.4
Di Tomaso, E.5
Maira, S.M.6
-
125
-
-
33645238619
-
Dominant-negative Rac increases both inherent and ionizing radiation-induced cell migration in C6 rat glioma cells
-
Hwang S.Y., Jung J.W., Jeong J.S., Kim Y.J., Oh E.S., Kim T.H., et al. Dominant-negative Rac increases both inherent and ionizing radiation-induced cell migration in C6 rat glioma cells. Int J Cancer 2006, 118(8):2056-2063.
-
(2006)
Int J Cancer
, vol.118
, Issue.8
, pp. 2056-2063
-
-
Hwang, S.Y.1
Jung, J.W.2
Jeong, J.S.3
Kim, Y.J.4
Oh, E.S.5
Kim, T.H.6
-
126
-
-
78650383580
-
Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology
-
Eschenhagen T., Force T., Ewer M.S., de Keulenaer G.W., Suter T.M., Anker S.D., et al. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail 2011, 13(1):1-10.
-
(2011)
Eur J Heart Fail
, vol.13
, Issue.1
, pp. 1-10
-
-
Eschenhagen, T.1
Force, T.2
Ewer, M.S.3
de Keulenaer, G.W.4
Suter, T.M.5
Anker, S.D.6
|