Effects of doxorubicin cancer therapy on autophagy and the ubiquitin-proteasome system in long-term cultured adult rat cardiomyocytes

Cell and Tissue Research

Volumn 350, Issue 2, 2012, Pages 361-372

  Dimitrakis, Polychronis ^a   Romay Ogando, Maria Iris ^a   Timolati, Francesco ^a   Suter, Thomas M ^a   Zuppinger, Christian ^b  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Apoptosis; Autophagy; Cardiomyocytes; Doxorubicin; Proteasome; Rat (Wistar adult male)

Indexed keywords

ANTHRACYCLINE; CATHEPSIN D; CHLOROQUINE; CHYMOTRYPSIN; DOXORUBICIN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MICROTUBULE ASSOCIATED PROTEIN 1; MUSCLE PROTEIN; MUSCLE RING FINGER 1 PROTEIN; PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UBIQUITINATED PROTEIN;

ADULT ANIMAL; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CHEMOTHERAPY; CARDIOTOXICITY; CELL AGING; CELL DEATH; CELL STRESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFECT; DRUG SENSITIVITY; ENZYME ACTIVITY; HEART CELL CULTURE; HEART MUSCLE CELL; IMAGING; LYSOSOME; MALE; MUSCLE FIBRIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; AUTOPHAGY; CELLS, CULTURED; DOXORUBICIN; MALE; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, WISTAR; UBIQUITIN;

RATTUS;

EID: 84871219987     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-012-1475-8     Document Type: Article

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