Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism

Cancer Detection and Prevention

Volumn 29, Issue 3, 2005, Pages 294-299

  Wold, Loren E ^a   Aberle II, Nicholas S ^a   Ren, Jun ^a,b  

^a UNIVERSITY OF NORTH DAKOTA   (United States)

^b UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

Author keywords

Cardiac myocytes; Doxorubicin; Oxidative stress; Relengthening; Shortening

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTIOXIDANT; ASCORBIC ACID; CALCIUM ION; DOXORUBICIN; FLUORESCEIN DIACETATE; FLUORESCENT DYE; FURA 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CARDIOTOXICITY; CONTROLLED STUDY; HEART MUSCLE CELL; HEART VENTRICLE; HEART VENTRICLE CONTRACTION; INCUBATION TIME; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; VELOCITY;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CALCIUM; DOXORUBICIN; HEART VENTRICLES; MALE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 20344398645     PISSN: 0361090X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cdp.2004.07.008     Document Type: Article

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