Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke

International Journal of Molecular Sciences

Volumn 14, Issue 9, 2013, Pages 18899-18924

  Kikuchi, Kiyoshi ^a,b   Tancharoen, Salunya ^a   Ito, Takashi ^c   Morimoto Yamashita, Yoko ^c   Miura, Naoki ^d   Kawahara, Ko ichi ^e   Maruyama, Ikuro ^c   Murai, Yoshinaka ^b   Tanaka, Eiichiro ^b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

^d KAGOSHIMA UNIVERSITY   (Japan)

^e OSAKA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Candesartan; High mobility group box 1; Irbesartan; Receptor for advanced glycation end products; Stroke; Telmisartan

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CANDESARTAN; CLOPIDOGREL; HIGH MOBILITY GROUP B1 PROTEIN; IRBESARTAN; LOSARTAN; NITRIC OXIDE; PLACEBO; RAMIPRIL; REACTIVE OXYGEN METABOLITE; TELMISARTAN; VALSARTAN;

ACUTE HEART INFARCTION; ATHEROSCLEROSIS; CEREBROVASCULAR ACCIDENT; CHEMOPROPHYLAXIS; DIABETES MELLITUS; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG TARGETING; HEART ATRIUM FIBRILLATION; HEART FAILURE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; NEUROPROTECTION; PROTEIN FUNCTION; REVIEW; RISK FACTOR;

ACUTE DISEASE; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANIMALS; BENZIMIDAZOLES; BENZOATES; BIPHENYL COMPOUNDS; HMGB1 PROTEIN; HUMANS; HYPERTENSION; NEURONS; RECEPTORS, IMMUNOLOGIC; RISK FACTORS; STROKE; TETRAZOLES;

EID: 84884185716     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140918899     Document Type: Review

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