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Volumn 4 FEB, Issue , 2013, Pages

Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias

Author keywords

Bifurcation analysis; Calcium window current; Early afterdepolarization; Fibrosis; Oxidative stress; Ventricular fibrillation

Indexed keywords

ANGIOTENSIN II; ANTIARRHYTHMIC AGENT; ANTIFIBROTIC AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CONNECTIVE TISSUE GROWTH FACTOR; CONNEXIN 43; ENDOTHELIN 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84884174839     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00019     Document Type: Review
Times cited : (27)

References (124)
  • 1
    • 77951281040 scopus 로고    scopus 로고
    • Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes
    • Ago, T., Kuroda, J., Pain, J., Fu, C., Li, H., and Sadoshima, J. (2010). Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ. Res. 106, 1253-1264.
    • (2010) Circ. Res. , vol.106 , pp. 1253-1264
    • Ago, T.1    Kuroda, J.2    Pain, J.3    Fu, C.4    Li, H.5    Sadoshima, J.6
  • 2
    • 0036213905 scopus 로고    scopus 로고
    • Cellular electrophysiologic properties of old canine atria provide a substrate for arrhythmogenesis
    • Anyukhovsky, E. P., Sosunov, E. A., Plotnikov, A., Gainullin, R. Z., Jhang, J. S., Marboe, C. C., et al. (2002). Cellular electrophysiologic properties of old canine atria provide a substrate for arrhythmogenesis. Cardiovasc. Res. 54, 462-469.
    • (2002) Cardiovasc. Res. , vol.54 , pp. 462-469
    • Anyukhovsky, E.P.1    Sosunov, E.A.2    Plotnikov, A.3    Gainullin, R.Z.4    Jhang, J.S.5    Marboe, C.C.6
  • 3
    • 0015980458 scopus 로고
    • The effect of resting potential on the electrical activity of canine cardiac Purkinje fibers exposed to Na-free solution or to ouabain
    • Aronson, R. S., and Cranefield, P. F. (1974). The effect of resting potential on the electrical activity of canine cardiac Purkinje fibers exposed to Na-free solution or to ouabain. Pflugers Arch. 347, 101-116.
    • (1974) Pflugers Arch , vol.347 , pp. 101-116
    • Aronson, R.S.1    Cranefield, P.F.2
  • 4
    • 0030888769 scopus 로고    scopus 로고
    • Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart
    • Asano, Y., Davidenko, J. M., Baxter, W. T., Gray, R. A., and Jalife, J. (1997). Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart. J. Am. Coll. Cardiol. 29, 831-842.
    • (1997) J. Am. Coll. Cardiol. , vol.29 , pp. 831-842
    • Asano, Y.1    Davidenko, J.M.2    Baxter, W.T.3    Gray, R.A.4    Jalife, J.5
  • 5
    • 84861782437 scopus 로고    scopus 로고
    • Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarizations-mediated ventricular arrhythmias
    • Bapat, A., Nguyen, T. P., Lee, J. H., Sovari, A. A., Fishbein, M. C., Weiss, J. N., et al. (2012). Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarizations-mediated ventricular arrhythmias. Am. J. Physiol. Heart Circ. Physiol. 302, H2331-H2340.
    • (2012) Am. J. Physiol. Heart Circ. Physiol. , vol.302
    • Bapat, A.1    Nguyen, T.P.2    Lee, J.H.3    Sovari, A.A.4    Fishbein, M.C.5    Weiss, J.N.6
  • 6
    • 84885381436 scopus 로고    scopus 로고
    • Arrhythmogenic effects of chronic and acute angiotensin II signaling in rat ventricles
    • Bapat, A., Umar, S., Stepanyan, H., Shwartz, K., Budas, G., Shryock, J., et al. (2012). Arrhythmogenic effects of chronic and acute angiotensin II signaling in rat ventricles. Heart Rhythm. 5, S182.
    • (2012) Heart Rhythm , vol.5
    • Bapat, A.1    Umar, S.2    Stepanyan, H.3    Shwartz, K.4    Budas, G.5    Shryock, J.6
  • 7
    • 84861863431 scopus 로고    scopus 로고
    • Targeting endoglin, an auxiliary transforming growth factor beta coreceptor, to prevent fibrosis and heart failure
    • Benjamin, I. J. (2012). Targeting endoglin, an auxiliary transforming growth factor beta coreceptor, to prevent fibrosis and heart failure. Circulation 125, 2689-2691.
    • (2012) Circulation , vol.125 , pp. 2689-2691
    • Benjamin, I.J.1
  • 8
    • 0029097799 scopus 로고
    • Molecular mechanism for an inherited cardiac arrhythmia
    • Bennett, P. B., Yazawa, K., Makita, N., and George, A. L. Jr. (1995). Molecular mechanism for an inherited cardiac arrhythmia. Nature 376, 683-685.
    • (1995) Nature , vol.376 , pp. 683-685
    • Bennett, P.B.1    Yazawa, K.2    Makita, N.3    George Jr, A.L.4
  • 9
    • 84869804074 scopus 로고    scopus 로고
    • Effects of myocardial fibrosis assessed by MRI on dynamic left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy: a retrospective database analysis
    • doi: 10.1136/bmjopen-2012-001267
    • Biagini, E., Lorenzini, M., Olivotto, I., Rocchi, G., Lovato, L., Lai, F., et al. (2012). Effects of myocardial fibrosis assessed by MRI on dynamic left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy: a retrospective database analysis. BMJ Open 2. pii: e001267. doi: 10.1136/bmjopen-2012-001267
    • (2012) BMJ Openz , vol.2
    • Biagini, E.1    Lorenzini, M.2    Olivotto, I.3    Rocchi, G.4    Lovato, L.5    Lai, F.6
  • 10
    • 0001662349 scopus 로고
    • Resonance, Tacoma Narrows bridg failure, and undergraduate physics textbooks
    • Billah, K. Y., and Scanlan, R. H. (1991). Resonance, Tacoma Narrows bridg failure, and undergraduate physics textbooks. Am. J. Phys. 59, 118-124.
    • (1991) Am. J. Phys. , vol.59 , pp. 118-124
    • Billah, K.Y.1    Scanlan, R.H.2
  • 11
    • 0038663006 scopus 로고    scopus 로고
    • Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity
    • Burashnikov, A., and Antzelevitch, C. (2003). Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity. Circulation 107, 2355-2360.
    • (2003) Circulation , vol.107 , pp. 2355-2360
    • Burashnikov, A.1    Antzelevitch, C.2
  • 12
    • 1942438638 scopus 로고    scopus 로고
    • Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction
    • Camelliti, P., Devlin, G. P., Matthews, K. G., Kohl, P., and Green, C. R. (2004). Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction. Cardiovasc. Res. 62, 415-425.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 415-425
    • Camelliti, P.1    Devlin, G.P.2    Matthews, K.G.3    Kohl, P.4    Green, C.R.5
  • 13
    • 0035860747 scopus 로고    scopus 로고
    • Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation
    • Carnes, C. A., Chung, M. K., Nakayama, T., Nakayama, H., Baliga, R. S., Piao, S., et al. (2001). Ascorbate attenuates atrial pacing-induced peroxynitrite formation and electrical remodeling and decreases the incidence of postoperative atrial fibrillation. Circ. Res. 89, E32-E38.
    • (2001) Circ. Res. , vol.89
    • Carnes, C.A.1    Chung, M.K.2    Nakayama, T.3    Nakayama, H.4    Baliga, R.S.5    Piao, S.6
  • 15
    • 84862645175 scopus 로고    scopus 로고
    • Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers
    • Chang, M. G., Chang, C. Y., de Lange, E., Xu, L., O'Rourke, B., Karagueuzian, H. S., et al. (2012a). Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophys. J. 102, 2706-2714.
    • (2012) Biophys. J. , vol.102 , pp. 2706-2714
    • Chang, M.G.1    Chang, C.Y.2    de Lange, E.3    Xu, L.4    O'Rourke, B.5    Karagueuzian, H.S.6
  • 16
    • 84555213142 scopus 로고    scopus 로고
    • Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias
    • Chang, M. G., Sato, D., de Lange, E., Lee, J. H., Karagueuzian, H. S., Garfinkel, A., et al. (2012b). Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias. Heart Rhythm. 9, 115-122.
    • (2012) Heart Rhythm , vol.9 , pp. 115-122
    • Chang, M.G.1    Sato, D.2    de Lange, E.3    Lee, J.H.4    Karagueuzian, H.S.5    Garfinkel, A.6
  • 17
    • 0025178623 scopus 로고
    • Low dimensional chaos in cardiac tissue
    • Chialvo, D. R., Gilmour, R. F. Jr., and Jalife, J. (1990). Low dimensional chaos in cardiac tissue. Nature 343, 653-657.
    • (1990) Nature , vol.343 , pp. 653-657
    • Chialvo, D.R.1    Gilmour Jr, R.F.2    Jalife, J.3
  • 18
    • 0023546965 scopus 로고
    • Non-linear dynamics of cardiac excitation and impulse propagation
    • Chialvo, D. R., and Jalife, J. (1987). Non-linear dynamics of cardiac excitation and impulse propagation. Nature 330, 749-752.
    • (1987) Nature , vol.330 , pp. 749-752
    • Chialvo, D.R.1    Jalife, J.2
  • 19
    • 0036707486 scopus 로고    scopus 로고
    • Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome
    • Choi, B. R., Burton, F., and Salama, G. (2002). Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome. J. Physiol. 543(2), 615-631.
    • (2002) J. Physiol. , vol.543 , Issue.2 , pp. 615-631
    • Choi, B.R.1    Burton, F.2    Salama, G.3
  • 20
    • 12844272885 scopus 로고    scopus 로고
    • Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels
    • Clancy, C. E., and Kass, R. S. (2005). Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels. Physiol. Rev. 85, 33-47.
    • (2005) Physiol. Rev. , vol.85 , pp. 33-47
    • Clancy, C.E.1    Kass, R.S.2
  • 21
    • 0025176816 scopus 로고
    • Intrinsic firing patterns of diverse neocortical neurons
    • Connors, B. W., and Gutnick, M. J. (1990). Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci. 13, 99-104.
    • (1990) Trends Neurosci , vol.13 , pp. 99-104
    • Connors, B.W.1    Gutnick, M.J.2
  • 22
    • 84885377723 scopus 로고
    • [The effect of increased levels of carbon dioxide on cardiac tissue studies with the aid of intracellular microelectrodes]
    • Coraboeuf, E., and Boistel, J. (1953). [The effect of increased levels of carbon dioxide on cardiac tissue studies with the aid of intracellular microelectrodes.]. C. R. Seances Soc. Biol. Fil. 147, 654-658.
    • (1953) C. R. Seances Soc. Biol. Fil. , vol.147 , pp. 654-658
    • Coraboeuf, E.1    Boistel, J.2
  • 23
    • 0025989181 scopus 로고
    • Glycolytic inhibition and calcium overload as consequences of exogenously generated free radicals in rabbit hearts
    • Corretti, M. C., Koretsune, Y., Kusuoka, H., Chacko, V. P., Zweier, J. L., and Marban, E. (1991). Glycolytic inhibition and calcium overload as consequences of exogenously generated free radicals in rabbit hearts. J. Clin. Invest. 88, 1014-1025.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1014-1025
    • Corretti, M.C.1    Koretsune, Y.2    Kusuoka, H.3    Chacko, V.P.4    Zweier, J.L.5    Marban, E.6
  • 25
    • 0017695423 scopus 로고
    • Action potentials, afterpotentials, and arrhythmias
    • Cranefield, P. F. (1977). Action potentials, afterpotentials, and arrhythmias. Circ. Res. 41, 415-423.
    • (1977) Circ. Res. , vol.41 , pp. 415-423
    • Cranefield, P.F.1
  • 26
    • 0021264274 scopus 로고
    • Effects of pacing on triggered activity induced by early afterdepolarizations
    • Damiano, B. P., and Rosen, M. R. (1984). Effects of pacing on triggered activity induced by early afterdepolarizations. Circulation 69, 1013-1025.
    • (1984) Circulation , vol.69 , pp. 1013-1025
    • Damiano, B.P.1    Rosen, M.R.2
  • 27
    • 0007950217 scopus 로고
    • Experimental cardiac arrhythmias and quinidine-like drugs
    • Dawes, G. S. (1952). Experimental cardiac arrhythmias and quinidine-like drugs. Pharmacol. Rev. 4, 43-84.
    • (1952) Pharmacol. Rev. , vol.4 , pp. 43-84
    • Dawes, G.S.1
  • 28
    • 0023872278 scopus 로고
    • Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation
    • de Bakker, J. M. T., van Capelle, F. J. L., Janse, M. J., Wilde, A. A. M., Coronel, R., Becker, A. E., et al. (1988). Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation. Circulation 77, 589-606.
    • (1988) Circulation , vol.77 , pp. 589-606
    • de Bakker, J.M.T.1    van Capelle, F.J.L.2    Janse, M.J.3    Wilde, A.A.M.4    Coronel, R.5    Becker, A.E.6
  • 29
    • 79960108482 scopus 로고    scopus 로고
    • CaMKII in the cardiovascular system: sensing redox states
    • Erickson, J. R., He, B. J., Grumbach, I. M., and Anderson, M. E. (2011). CaMKII in the cardiovascular system: sensing redox states. Physiol. Rev. 91, 889-915.
    • (2011) Physiol. Rev. , vol.91 , pp. 889-915
    • Erickson, J.R.1    He, B.J.2    Grumbach, I.M.3    Anderson, M.E.4
  • 30
    • 42949085382 scopus 로고    scopus 로고
    • A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
    • Erickson, J. R., Joiner, M. L., Guan, X., Kutschke, W., Yang, J., Oddis, C. V., et al. (2008). A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 133, 462-474.
    • (2008) Cell , vol.133 , pp. 462-474
    • Erickson, J.R.1    Joiner, M.L.2    Guan, X.3    Kutschke, W.4    Yang, J.5    Oddis, C.V.6
  • 32
    • 0042232510 scopus 로고    scopus 로고
    • Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin
    • Gaudesius, G., Miragoli, M., Thomas, S. P., and Rohr, S. (2003). Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin. Circ. Res. 93, 421-428.
    • (2003) Circ. Res. , vol.93 , pp. 421-428
    • Gaudesius, G.1    Miragoli, M.2    Thomas, S.P.3    Rohr, S.4
  • 33
    • 0029094843 scopus 로고
    • A model for circadian oscillations in the Drosophila period protein (PER)
    • Goldbeter, A. (1995). A model for circadian oscillations in the Drosophila period protein (PER). Proc. Biol. Sci. 261, 319-324.
    • (1995) Proc. Biol. Sci. , vol.261 , pp. 319-324
    • Goldbeter, A.1
  • 34
    • 0015419716 scopus 로고
    • Dissipative structures for an allosteric model. Application to glycolytic oscillations
    • Goldbeter, A., and Lefever, R. (1972). Dissipative structures for an allosteric model. Application to glycolytic oscillations. Biophys. J. 12, 1302-1315.
    • (1972) Biophys. J. , vol.12 , pp. 1302-1315
    • Goldbeter, A.1    Lefever, R.2
  • 35
    • 33750740174 scopus 로고    scopus 로고
    • Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes
    • Goldhaber, J. I. (1996). Free radicals enhance Na+/Ca2+ exchange in ventricular myocytes. Am. J. Physiol. 271(3 2), H823-H833.
    • (1996) Am. J. Physiol. , vol.271 , Issue.32
    • Goldhaber, J.I.1
  • 36
    • 0026752518 scopus 로고
    • Three ways of abolishing automaticity in sinoatrial node: ionic modeling and nonlinear dynamics
    • Guevara, M. R., and Jongsma, H. J. (1992). Three ways of abolishing automaticity in sinoatrial node: ionic modeling and nonlinear dynamics. Am. J. Physiol. 262(4 2), H1268-H1286.
    • (1992) Am. J. Physiol. , vol.262 , Issue.42
    • Guevara, M.R.1    Jongsma, H.J.2
  • 37
    • 0019815049 scopus 로고
    • Phase locking, period-doubling bifurcations, and irregular dynamics in periodically stimulated cardiac cells
    • Guevara, M. R., Glass, L., and Shrier, A. (1981). Phase locking, period-doubling bifurcations, and irregular dynamics in periodically stimulated cardiac cells. Science 214, 1350-1353.
    • (1981) Science , vol.214 , pp. 1350-1353
    • Guevara, M.R.1    Glass, L.2    Shrier, A.3
  • 38
    • 0021642311 scopus 로고
    • Electrical alternans and period-doubling bifurcations
    • Guevara, M. R., Shrier, A., and Glass, L. (1984). Electrical alternans and period-doubling bifurcations. Comput. Cardiol. 1, 167-170.
    • (1984) Comput. Cardiol. , vol.1 , pp. 167-170
    • Guevara, M.R.1    Shrier, A.2    Glass, L.3
  • 39
    • 0014444074 scopus 로고
    • The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres
    • Hauswirth, O., Noble, D., and Tsien, R. W. (1969). The mechanism of oscillatory activity at low membrane potentials in cardiac Purkinje fibres. J. Physiol. 200, 255-265.
    • (1969) J. Physiol. , vol.200 , pp. 255-265
    • Hauswirth, O.1    Noble, D.2    Tsien, R.W.3
  • 43
    • 50949134255 scopus 로고    scopus 로고
    • QT prolongation is an unreliable predictor of ventricular arrhythmia
    • Hondeghem, L. M. (2008). QT prolongation is an unreliable predictor of ventricular arrhythmia. Heart Rhythm. 5, 1210-1212.
    • (2008) Heart Rhythm , vol.5 , pp. 1210-1212
    • Hondeghem, L.M.1
  • 44
    • 0033855288 scopus 로고    scopus 로고
    • Electrotonic suppression of early afterdepolarizations in isolated rabbit Purkinje myocytes 1
    • Huelsing, D. J., Spitzer, K. W., and Pollard, A. E. (2000). Electrotonic suppression of early afterdepolarizations in isolated rabbit Purkinje myocytes 1. Am. J. Physiol. Heart Circ. Physiol. 279, H250-H259.
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.279
    • Huelsing, D.J.1    Spitzer, K.W.2    Pollard, A.E.3
  • 45
    • 0000980131 scopus 로고
    • Anion conductance of cardiac muscle
    • Hutter, O. F., and Noble, D. (1961). Anion conductance of cardiac muscle. J. Physiol. 157, 335-350.
    • (1961) J. Physiol. , vol.157 , pp. 335-350
    • Hutter, O.F.1    Noble, D.2
  • 46
    • 0021646404 scopus 로고
    • The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes
    • Isenberg, G., and Ravens, U. (1984). The effects of the Anemonia sulcata toxin (ATX II) on membrane currents of isolated mammalian myocytes. J. Physiol. 357, 127-149.
    • (1984) J. Physiol. , vol.357 , pp. 127-149
    • Isenberg, G.1    Ravens, U.2
  • 47
    • 44949135059 scopus 로고    scopus 로고
    • Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure model
    • Jacquemet, V., and Henriquez, C. S. (2008). Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure model. Am. J. Physiol. Heart Circ. Physiol. 294, H2040-H2052.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Jacquemet, V.1    Henriquez, C.S.2
  • 48
    • 0024556795 scopus 로고
    • Early afterdepolarizations: mechanism of induction and block A role for L-type Ca2+ current
    • January, C. T., and Riddle, J. M. (1989). Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current. Circ. Res. 64, 977-990.
    • (1989) Circ. Res. , vol.64 , pp. 977-990
    • January, C.T.1    Riddle, J.M.2
  • 49
    • 0023856250 scopus 로고
    • A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K (8644)
    • January, C. T., Riddle, J. M., and Salata, J. J. (1988). A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay, K (8644). Circ. Res. 62, 563-571.
    • (1988) Circ. Res. , vol.62 , pp. 563-571
    • January, C.T.1    Riddle, J.M.2    Salata, J.J.3
  • 50
    • 84861841591 scopus 로고    scopus 로고
    • Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure
    • Kapur, N. K., Wilson, S., Yunis, A. A., Qiao, X., Mackey, E., Paruchuri, V., et al. (2012). Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure. Circulation 125, 2728-2738.
    • (2012) Circulation , vol.125 , pp. 2728-2738
    • Kapur, N.K.1    Wilson, S.2    Yunis, A.A.3    Qiao, X.4    Mackey, E.5    Paruchuri, V.6
  • 51
    • 0027302455 scopus 로고
    • Action potential alternans and irregular dynamics in quinidine-intoxicated ventricular muscle cells Implications for ventricular proarrhythmia
    • Karagueuzian, H. S., Khan, S. S., Hong, K., Kobayashi, Y., Denton, T., Mandel, W. J., et al. (1993). Action potential alternans and irregular dynamics in quinidine-intoxicated ventricular muscle cells. Implications for ventricular proarrhythmia. Circulation 87, 1661-1672.
    • (1993) Circulation , vol.87 , pp. 1661-1672
    • Karagueuzian, H.S.1    Khan, S.S.2    Hong, K.3    Kobayashi, Y.4    Denton, T.5    Mandel, W.J.6
  • 52
    • 0016799955 scopus 로고
    • Effects of extracellular calcium and sodium on depolarization-induced automaticity in guinea pig papillary muscle
    • Katzung, B. (1975). Effects of extracellular calcium and sodium on depolarization-induced automaticity in guinea pig papillary muscle. Circ. Res. 37, 118-127.
    • (1975) Circ. Res. , vol.37 , pp. 118-127
    • Katzung, B.1
  • 53
    • 84864182823 scopus 로고    scopus 로고
    • Assessment of myocardial scarring improves risk stratification in patients evaluated for cardiac defibrillator implantation
    • Klem, I., Weinsaft, J. W., Bahnson, T. D., Hegland, D., Kim, H. W., Hayes, B., et al. (2012). Assessment of myocardial scarring improves risk stratification in patients evaluated for cardiac defibrillator implantation. J. Am. Coll. Cardiol. 60, 408-420.
    • (2012) J. Am. Coll. Cardiol. , vol.60 , pp. 408-420
    • Klem, I.1    Weinsaft, J.W.2    Bahnson, T.D.3    Hegland, D.4    Kim, H.W.5    Hayes, B.6
  • 54
    • 84857533145 scopus 로고    scopus 로고
    • Fibroblast-myocyte connections in the heart
    • Kohl, P., and Camelliti, P. (2012). Fibroblast-myocyte connections in the heart. Heart Rhythm. 9, 461-464.
    • (2012) Heart Rhythm , vol.9 , pp. 461-464
    • Kohl, P.1    Camelliti, P.2
  • 55
    • 34047182621 scopus 로고    scopus 로고
    • TGFbeta, cardiac fibroblasts, and the fibrotic response
    • Leask, A. (2007). TGFbeta, cardiac fibroblasts, and the fibrotic response. Cardiovasc. Res. 74, 207-212.
    • (2007) Cardiovasc. Res. , vol.74 , pp. 207-212
    • Leask, A.1
  • 56
    • 77953808712 scopus 로고    scopus 로고
    • Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation
    • Leask, A. (2010). Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation. Circ. Res. 106, 1675-1680.
    • (2010) Circ. Res. , vol.106 , pp. 1675-1680
    • Leask, A.1
  • 57
    • 33750223425 scopus 로고    scopus 로고
    • 4th., Rahmutula, D., Guerra, J. M., Wilson, E., Ding, C., et al
    • Lee, K. W., Everett, T. H. 4th., Rahmutula, D., Guerra, J. M., Wilson, E., Ding, C., et al. (2006). Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure. Circulation 114, 1703-1712.
    • (2006) Circulation , vol.114 , pp. 1703-1712
    • Lee, K.W.1    Everett, T.H.2
  • 58
    • 84867575160 scopus 로고    scopus 로고
    • Left ventricular midwall fibrosis as a predictor of mortality and morbidity after cardiac resynchronization therapy in patients with nonischemic cardiomyopathy
    • Leyva, F., Taylor, R., Foley, P. W., Umar, F., Mulligan, L. J., Patel, K., et al. (2012). Left ventricular midwall fibrosis as a predictor of mortality and morbidity after cardiac resynchronization therapy in patients with nonischemic cardiomyopathy. J. Am. Coll. Cardiol. 60, 1659-1667.
    • (2012) J. Am. Coll. Cardiol. , vol.60 , pp. 1659-1667
    • Leyva, F.1    Taylor, R.2    Foley, P.W.3    Umar, F.4    Mulligan, L.J.5    Patel, K.6
  • 59
    • 0035923479 scopus 로고    scopus 로고
    • Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure
    • Li, D., Shinagawa, K., Pang, L., Leung, T. K., Cardin, S., Wang, Z., et al. (2001). Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure. Circulation 104, 2608-2614.
    • (2001) Circulation , vol.104 , pp. 2608-2614
    • Li, D.1    Shinagawa, K.2    Pang, L.3    Leung, T.K.4    Cardin, S.5    Wang, Z.6
  • 60
    • 84892794173 scopus 로고
    • The normal membrnae potential of frog sartorius fibers
    • Ling, G., and Gerard, R. W. (1949). The normal membrnae potential of frog sartorius fibers. J. Cell. Comp. Physiol. 34, 383-396.
    • (1949) J. Cell. Comp. Physiol. , vol.34 , pp. 383-396
    • Ling, G.1    Gerard, R.W.2
  • 61
    • 14844361721 scopus 로고    scopus 로고
    • Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure
    • Lokuta, A. J., Maertz, N. A., Meethal, S. V., Potter, K. T., Kamp, T. J., Valdivia, H. H., et al. (2005). Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure. Circulation 111, 988-995.
    • (2005) Circulation , vol.111 , pp. 988-995
    • Lokuta, A.J.1    Maertz, N.A.2    Meethal, S.V.3    Potter, K.T.4    Kamp, T.J.5    Valdivia, H.H.6
  • 62
    • 34547933258 scopus 로고    scopus 로고
    • Identification of a potential cardiac antifibrotic mechanism of torasemide in patients with chronic heart failure
    • Lopez, B., Gonzalez, A., Beaumont, J., Querejeta, R., Larman, M., and Diez, J. (2007). Identification of a potential cardiac antifibrotic mechanism of torasemide in patients with chronic heart failure. J. Am. Coll. Cardiol. 50, 859-867.
    • (2007) J. Am. Coll. Cardiol. , vol.50 , pp. 859-867
    • Lopez, B.1    Gonzalez, A.2    Beaumont, J.3    Querejeta, R.4    Larman, M.5    Diez, J.6
  • 63
    • 33846508259 scopus 로고    scopus 로고
    • A mathematical model of electrotonic interactions between ventricular myocytes and fibroblasts
    • MacCannell, E., Bazzazi, H., Chilton, I., Shibukawa, Y., Clerk, R. B., and Giles, W. R. (2007). A mathematical model of electrotonic interactions between ventricular myocytes and fibroblasts. Biophys. J. 92, 4121-4132.
    • (2007) Biophys. J. , vol.92 , pp. 4121-4132
    • MacCannell, E.1    Bazzazi, H.2    Chilton, I.3    Shibukawa, Y.4    Clerk, R.B.5    Giles, W.R.6
  • 64
    • 83455220119 scopus 로고    scopus 로고
    • Shaping a new Ca(2)(+) conductance to suppress early afterdepolarizations in cardiac myocytes
    • Madhvani, R. V., Xie, Y., Pantazis, A., Garfinkel, A., Qu, Z., Weiss, J. N., et al. (2011). Shaping a new Ca(2)(+) conductance to suppress early afterdepolarizations in cardiac myocytes. J. Physiol. 589(24), 6081-6092.
    • (2011) J. Physiol. , vol.589 , Issue.24 , pp. 6081-6092
    • Madhvani, R.V.1    Xie, Y.2    Pantazis, A.3    Garfinkel, A.4    Qu, Z.5    Weiss, J.N.6
  • 65
    • 79953791303 scopus 로고    scopus 로고
    • Genesis of phase-3 early afterdepolarizations and triggered activity in acquired long QT syndrome
    • Maruyama, M., Lin, S. F., Xie, Y., Chua, S. K., Joung, B., Han, S., et al. (2011). Genesis of phase-3 early afterdepolarizations and triggered activity in acquired long QT syndrome. Circ. Arrhythm. Electrophysiol. 1, 103-111.
    • (2011) Circ. Arrhythm. Electrophysiol. , vol.1 , pp. 103-111
    • Maruyama, M.1    Lin, S.F.2    Xie, Y.3    Chua, S.K.4    Joung, B.5    Han, S.6
  • 66
    • 77956319635 scopus 로고    scopus 로고
    • Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype
    • Massare, J., Berry, J. M., Luo, X., Rob, F., Johnstone, J. L., Shelton, J. M., et al. (2010). Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype. J. Cardiovasc. Electrophysiol. 21, 1031-1037.
    • (2010) J. Cardiovasc. Electrophysiol. , vol.21 , pp. 1031-1037
    • Massare, J.1    Berry, J.M.2    Luo, X.3    Rob, F.4    Johnstone, J.L.5    Shelton, J.M.6
  • 67
    • 77956676452 scopus 로고    scopus 로고
    • Association of left atrial endothelin-1 with atrial rhythm, size, and fibrosis in patients with structural heart disease
    • Mayyas, F., Niebauer, M., Zurick, A., Barnard, J., Gillinov, A. M., Chung, M. K., et al. (2010). Association of left atrial endothelin-1 with atrial rhythm, size, and fibrosis in patients with structural heart disease. Circ. Arrhythm. Electrophysiol. 3, 369-379.
    • (2010) Circ. Arrhythm. Electrophysiol. , vol.3 , pp. 369-379
    • Mayyas, F.1    Niebauer, M.2    Zurick, A.3    Barnard, J.4    Gillinov, A.M.5    Chung, M.K.6
  • 68
    • 0038721853 scopus 로고    scopus 로고
    • Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance
    • McCrohon, J. A., Moon, J. C., Prasad, S. K., McKenna, W. J., Lorenz, C. H., Coats, A. J., et al. (2003). Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance. Circulation 108, 54-59.
    • (2003) Circulation , vol.108 , pp. 54-59
    • McCrohon, J.A.1    Moon, J.C.2    Prasad, S.K.3    McKenna, W.J.4    Lorenz, C.H.5    Coats, A.J.6
  • 69
    • 35448955300 scopus 로고    scopus 로고
    • Myofibroblasts induce ectopic activity in cardiac tissue
    • Miragoli, M., Salvarani, N., and Rohr, S. (2007). Myofibroblasts induce ectopic activity in cardiac tissue. Circ. Res. 101, 755-758.
    • (2007) Circ. Res. , vol.101 , pp. 755-758
    • Miragoli, M.1    Salvarani, N.2    Rohr, S.3
  • 70
    • 84857640089 scopus 로고    scopus 로고
    • Pathophysiology of the cardiac late Na current and its potential as a drug target
    • Moreno, J. D., and Clancy, C. E. (2012). Pathophysiology of the cardiac late Na current and its potential as a drug target. J. Mol. Cell. Cardiol. 52, 608-619.
    • (2012) J. Mol. Cell. Cardiol. , vol.52 , pp. 608-619
    • Moreno, J.D.1    Clancy, C.E.2
  • 72
    • 78651326450 scopus 로고    scopus 로고
    • Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine
    • Morita, N., Lee, J. H., Xie, Y., Sovari, A., Qu, Z., Weiss, J. N., et al. (2011b). Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine. J. Am. Coll. Cardiol. 57, 366-375.
    • (2011) J. Am. Coll. Cardiol. , vol.57 , pp. 366-375
    • Morita, N.1    Lee, J.H.2    Xie, Y.3    Sovari, A.4    Qu, Z.5    Weiss, J.N.6
  • 74
    • 77957255499 scopus 로고    scopus 로고
    • Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias
    • Nguyen, D. T., Ding, C., Wilson, E., Marcus, G. M., and Olgin, J. E. (2010). Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias. Heart Rhythm. 7, 1438-1445.
    • (2010) Heart Rhythm , vol.7 , pp. 1438-1445
    • Nguyen, D.T.1    Ding, C.2    Wilson, E.3    Marcus, G.M.4    Olgin, J.E.5
  • 75
    • 84856191694 scopus 로고    scopus 로고
    • Arrhythmogenic consequences of myofibroblast-myocyte coupling
    • Nguyen, T. P., Xie, Y., Garfinkel, A., Qu, Z., and Weiss, J. N. (2012). Arrhythmogenic consequences of myofibroblast-myocyte coupling. Cardiovasc. Res. 93, 242-251.
    • (2012) Cardiovasc. Res. , vol.93 , pp. 242-251
    • Nguyen, T.P.1    Xie, Y.2    Garfinkel, A.3    Qu, Z.4    Weiss, J.N.5
  • 76
    • 0014318908 scopus 로고
    • A graphic method for the study of alternation in cardiac action potentials
    • Nolasco, J. B., and Dahlen, R. W. (1968). A graphic method for the study of alternation in cardiac action potentials. J. Appl. Physiol. 25, 191-196.
    • (1968) J. Appl. Physiol. , vol.25 , pp. 191-196
    • Nolasco, J.B.1    Dahlen, R.W.2
  • 77
    • 77956343217 scopus 로고    scopus 로고
    • Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy
    • O'Hanlon, R., Grasso, A., Roughton, M., Moon, J. C., Clark, S., Wage, R., et al. (2010). Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 56, 867-874.
    • (2010) J. Am. Coll. Cardiol. , vol.56 , pp. 867-874
    • O'Hanlon, R.1    Grasso, A.2    Roughton, M.3    Moon, J.C.4    Clark, S.5    Wage, R.6
  • 78
    • 77956975963 scopus 로고    scopus 로고
    • Mechanisms of hypokalemia-induced ventricular arrhythmogenicity
    • Osadchii, O. E. (2010). Mechanisms of hypokalemia-induced ventricular arrhythmogenicity. Fundam. Clin. Pharmacol. 24, 547-559.
    • (2010) Fundam. Clin. Pharmacol. , vol.24 , pp. 547-559
    • Osadchii, O.E.1
  • 79
    • 0344982141 scopus 로고    scopus 로고
    • Dynamics of the cell cycle: checkpoints, sizers, and timers
    • Qu, Z., MacLellan, W. R., and Weiss, J. N. (2003). Dynamics of the cell cycle: checkpoints, sizers, and timers. Biophys. J. 85, 3600-3611.
    • (2003) Biophys. J. , vol.85 , pp. 3600-3611
    • Qu, Z.1    MacLellan, W.R.2    Weiss, J.N.3
  • 81
    • 67649547603 scopus 로고    scopus 로고
    • Sodium channel mutations and arrhythmias
    • Ruan, Y., Liu, N., and Priori, S. G. (2009). Sodium channel mutations and arrhythmias. Nat. Rev. Cardiol. 6, 337-348.
    • (2009) Nat. Rev. Cardiol. , vol.6 , pp. 337-348
    • Ruan, Y.1    Liu, N.2    Priori, S.G.3
  • 82
    • 0032942461 scopus 로고    scopus 로고
    • Influence of electrical coupling on early afterdepolarizations in ventricular myocytes
    • Saiz, J., Ferrero, J. M. Jr., Monserrat, M., Ferrero, J. M., and Thakor, N. V. (1999). Influence of electrical coupling on early afterdepolarizations in ventricular myocytes. IEEE Trans. Biomed. Eng. 46, 138-147.
    • (1999) IEEE Trans. Biomed. Eng. , vol.46 , pp. 138-147
    • Saiz, J.1    Ferrero Jr, J.M.2    Monserrat, M.3    Ferrero, J.M.4    Thakor, N.V.5
  • 83
    • 77955688268 scopus 로고    scopus 로고
    • Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophys
    • Sato, D., Xie, L. H., Nguyen, T. P., Weiss, J. N., and Qu, Z. (2010). Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophys. J. 99, 765-773.
    • (2010) J , vol.99 , pp. 765-773
    • Sato, D.1    Xie, L.H.2    Nguyen, T.P.3    Weiss, J.N.4    Qu, Z.5
  • 84
    • 62549104813 scopus 로고    scopus 로고
    • Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias
    • Sato, D., Xie, L. H., Sovari, A. A., Tran, D. X., Morita, N., Xie, F., et al. (2009). Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias. Proc. Natl. Acad. Sci. U.S.A. 106, 2983-2988.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 2983-2988
    • Sato, D.1    Xie, L.H.2    Sovari, A.A.3    Tran, D.X.4    Morita, N.5    Xie, F.6
  • 85
    • 0008858041 scopus 로고
    • Experiments with aconitine on the problem of spontaneous stimulus formation in the heart
    • Schmidt, R. S. (1960). Experiments with aconitine on the problem of spontaneous stimulus formation in the heart. Pflugers Arch. Gesamte Physiol. Menschen Tiere 271, 526-536.
    • (1960) Pflugers Arch. Gesamte Physiol. Menschen Tiere , vol.271 , pp. 526-536
    • Schmidt, R.S.1
  • 86
    • 33750236799 scopus 로고
    • L'influence de la phase supernormale d'éxcitabilité sur le rythme spontané ou provoqué des oreillettes droite et gauche du lapin. Extrasystolie et tachycardie paroxystique
    • Segers, M. (1939). L'influence de la phase supernormale d'éxcitabilité sur le rythme spontané ou provoqué des oreillettes droite et gauche du lapin. Extrasystolie et tachycardie paroxystique. C. R. Soc. Biol. (Paris) 130, 1359-1363.
    • (1939) C. R. Soc. Biol. (Paris) , vol.130 , pp. 1359-1363
    • Segers, M.1
  • 87
    • 84885374582 scopus 로고
    • Les mécanismes des réglagese l'amplitude des contractions cardiaques
    • Segers, M. (1942). Les mécanismes des réglagese l'amplitude des contractions cardiaques. Arch. Internat. Physiol. 52, 291-348.
    • (1942) Arch. Internat. Physiol. , vol.52 , pp. 291-348
    • Segers, M.1
  • 88
    • 0010319222 scopus 로고
    • Le battement auto-entretenu du coeur
    • Segers, M. (1947). Le battement auto-entretenu du coeur. Arch. Int. Pharmacodyn. 75, 144-156.
    • (1947) Arch. Int. Pharmacodyn. , vol.75 , pp. 144-156
    • Segers, M.1
  • 89
    • 21344463329 scopus 로고    scopus 로고
    • Refining detection of drug-induced proarrhythmia: QT interval and TRIaD
    • Shah, R. R., and Hondeghem, L. M. (2005). Refining detection of drug-induced proarrhythmia: QT interval and TRIaD. Heart Rhythm. 2, 758-772.
    • (2005) Heart Rhythm , vol.2 , pp. 758-772
    • Shah, R.R.1    Hondeghem, L.M.2
  • 90
    • 33745251122 scopus 로고    scopus 로고
    • Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction
    • Song, Y., Shryock, J. C., Wagner, S., Maier, L. S., and Belardinelli, L. (2006). Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction. J. Pharmacol. Exp. Ther. 318, 214-222.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 214-222
    • Song, Y.1    Shryock, J.C.2    Wagner, S.3    Maier, L.S.4    Belardinelli, L.5
  • 91
    • 71049156180 scopus 로고    scopus 로고
    • Bursting near Bautin bifurcation in a neural network with delay coupling
    • Song, Z., and Xu, J. (2009). Bursting near Bautin bifurcation in a neural network with delay coupling. Int. J. Neural. Syst. 19, 359-373.
    • (2009) Int. J. Neural. Syst. , vol.19 , pp. 359-373
    • Song, Z.1    Xu, J.2
  • 92
    • 80052490420 scopus 로고    scopus 로고
    • Myocardial fibrosis as a risk stratifier for sudden arrhythmic death
    • Sovari, A. A., and Karagueuzian, H. S. (2011). Myocardial fibrosis as a risk stratifier for sudden arrhythmic death. Expert Rev. Cardiovasc. Ther. 9, 951-953.
    • (2011) Expert Rev. Cardiovasc. Ther. , vol.9 , pp. 951-953
    • Sovari, A.A.1    Karagueuzian, H.S.2
  • 93
    • 0025933886 scopus 로고
    • Anisotropic structural complexities in the genesis of reentrant arrhythmias
    • Spach, M. S. (1991). Anisotropic structural complexities in the genesis of reentrant arrhythmias. Circulation 84, 1447-1450.
    • (1991) Circulation , vol.84 , pp. 1447-1450
    • Spach, M.S.1
  • 94
    • 0024829872 scopus 로고
    • Interaction of inhomogeneities of repolarization with anisotropic propagation in dog atria. A mechanism for both preventing and initiating reentry
    • Spach, M. S., Dolber, P. C., and Heidlage, J. F. (1989). Interaction of inhomogeneities of repolarization with anisotropic propagation in dog atria. A mechanism for both preventing and initiating reentry. Circ. Res. 65, 1612-1631.
    • (1989) Circ. Res. , vol.65 , pp. 1612-1631
    • Spach, M.S.1    Dolber, P.C.2    Heidlage, J.F.3
  • 95
    • 33846537841 scopus 로고    scopus 로고
    • Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study
    • Spach, M. S., Heidlage, F., Dolber, P. C., and Barr, R. C. (2007). Mechanism of origin of conduction disturbances in aging human atrial bundles: experimental and model study. Heart Rhythm. 4, 175-185.
    • (2007) Heart Rhythm , vol.4 , pp. 175-185
    • Spach, M.S.1    Heidlage, F.2    Dolber, P.C.3    Barr, R.C.4
  • 96
    • 77955448077 scopus 로고    scopus 로고
    • Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model
    • Stein, M., Boulaksil, M., Jansen, J. A., Herold, E., Noorman, M., Joles, J. A., et al. (2010). Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model. Am. J. Physiol. Heart Circ. Physiol. 299, H310-H321.
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.299
    • Stein, M.1    Boulaksil, M.2    Jansen, J.A.3    Herold, E.4    Noorman, M.5    Joles, J.A.6
  • 97
    • 79958119946 scopus 로고    scopus 로고
    • Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic prospects for up-regulation of SUR2A
    • Sudhir, R., Sukhodub, A., Du, Q., Jovanovic, S., and Jovanovic, A. (2011). Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic prospects for up-regulation of SUR2A. Biogerontology 12, 147-155.
    • (2011) Biogerontology , vol.12 , pp. 147-155
    • Sudhir, R.1    Sukhodub, A.2    Du, Q.3    Jovanovic, S.4    Jovanovic, A.5
  • 98
    • 0028973482 scopus 로고
    • Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
    • Sundaresan, M., Yu, Z. X., Ferrans, V. J., Irani, K., and Finkel, T. (1995). Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science 270, 296-299.
    • (1995) Science , vol.270 , pp. 296-299
    • Sundaresan, M.1    Yu, Z.X.2    Ferrans, V.J.3    Irani, K.4    Finkel, T.5
  • 99
    • 4544371157 scopus 로고    scopus 로고
    • Effect of ramipril in reducing sudden deaths and nonfatal cardiac arrests in high-risk individuals without heart failure or left ventricular dysfunction
    • Teo, K. K., Mitchell, L. B., Pogue, J., Bosch, J., Dagenais, G., and Yusuf, S. (2004). Effect of ramipril in reducing sudden deaths and nonfatal cardiac arrests in high-risk individuals without heart failure or left ventricular dysfunction. Circulation 110, 1413-1417.
    • (2004) Circulation , vol.110 , pp. 1413-1417
    • Teo, K.K.1    Mitchell, L.B.2    Pogue, J.3    Bosch, J.4    Dagenais, G.5    Yusuf, S.6
  • 100
    • 84865498608 scopus 로고    scopus 로고
    • Progression of myocardial fibrosis assessed with cardiac magnetic resonance in hypertrophic cardiomyopathy
    • Todiere, G., Aquaro, G. D., Piaggi, P., Formisano, F., Barison, A., Masci, P. G., et al. (2012). Progression of myocardial fibrosis assessed with cardiac magnetic resonance in hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 60, 922-929.
    • (2012) J. Am. Coll. Cardiol. , vol.60 , pp. 922-929
    • Todiere, G.1    Aquaro, G.D.2    Piaggi, P.3    Formisano, F.4    Barison, A.5    Masci, P.G.6
  • 101
    • 67649442642 scopus 로고    scopus 로고
    • Bifurcation and chaos in a model of cardiac early afterdepolarizations
    • Tran, D. X., Sato, D., Yochelis, A., Weiss, J. N., Garfinkel, A., and Qu, Z. (2009). Bifurcation and chaos in a model of cardiac early afterdepolarizations. Phys. Rev. Lett. 102, 258103.
    • (2009) Phys. Rev. Lett. , vol.102 , pp. 258103
    • Tran, D.X.1    Sato, D.2    Yochelis, A.3    Weiss, J.N.4    Garfinkel, A.5    Qu, Z.6
  • 102
    • 34347135423 scopus 로고
    • [The action current of the myocardial fibers in oxygen deficiency
    • Trautwein, W., Gottstein, U., and Dudel, J. (1954). [The action current of the myocardial fibers in oxygen deficiency.]. Pflugers Arch. 260, 40-60.
    • (1954) ]. Pflugers Arch. , vol.260 , pp. 40-60
    • Trautwein, W.1    Gottstein, U.2    Dudel, J.3
  • 103
    • 79551558054 scopus 로고    scopus 로고
    • High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy
    • doi:10.1371/journal.pone.0015287
    • Tyralla, K., Adamczak, M., Benz, K., Campean, V., Gross, M. L., Hilgers, K. F., et al. (2011). High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy. PLoS ONE 6:e15287. doi: 10.1371/journal.pone.0015287
    • (2011) PLoS ONE , vol.6
    • Tyralla, K.1    Adamczak, M.2    Benz, K.3    Campean, V.4    Gross, M.L.5    Hilgers, K.F.6
  • 104
    • 77958451496 scopus 로고    scopus 로고
    • Enhanced fibroblast-myocyte interactions in response to cardiac injury
    • Vasquez, C., Mohandas, P., Louie, K. L., Benamer, N., Bapat, A. C., and Morley, G. E. (2011). Enhanced fibroblast-myocyte interactions in response to cardiac injury. Circ. Res. 107, 1011-1020.
    • (2011) Circ. Res. , vol.107 , pp. 1011-1020
    • Vasquez, C.1    Mohandas, P.2    Louie, K.L.3    Benamer, N.4    Bapat, A.C.5    Morley, G.E.6
  • 105
    • 0034936504 scopus 로고    scopus 로고
    • O., van Ginneken, A. C., Baartscheer, A., Schumacher, C., de Jonge, N., et al
    • Veldkamp, M. W., Verkerk, A. O., van Ginneken, A. C., Baartscheer, A., Schumacher, C., de Jonge, N., et al. (2001). Norepinephrine induces action potential prolongation and early afterdepolarizations in ventricular myocytes isolated from human end-stage failing hearts. Eur. Heart J. 22, 955-963.
    • (2001) Eur. Heart J. , vol.22 , pp. 955-963
    • Veldkamp, M.W.1    Verkerk, A.2
  • 106
    • 0038649984 scopus 로고    scopus 로고
    • Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies Of Left Ventricular Dysfunction (SOLVD) trials
    • Vermes, E., Tardif, J. C., Bourassa, M. G., Racine, N., Levesque, S., White, M., et al. (2003). Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies Of Left Ventricular Dysfunction (SOLVD) trials. Circulation 107, 2926-2931.
    • (2003) Circulation , vol.107 , pp. 2926-2931
    • Vermes, E.1    Tardif, J.C.2    Bourassa, M.G.3    Racine, N.4    Levesque, S.5    White, M.6
  • 107
    • 0034077362 scopus 로고    scopus 로고
    • Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts
    • Volders, P. G., Vos, M. A., Szabo, B., Sipido, K. R., de Groot, S. H., Gorgels, A. P., et al. (2000). Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts. Cardiovasc. Res. 46, 376-392.
    • (2000) Cardiovasc. Res. , vol.46 , pp. 376-392
    • Volders, P.G.1    Vos, M.A.2    Szabo, B.3    Sipido, K.R.4    de Groot, S.H.5    Gorgels, A.P.6
  • 108
    • 0030957101 scopus 로고    scopus 로고
    • Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes
    • Ward, C. A., and Giles, W. R. (1997). Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes. J. Physiol. 500(3), 631-642.
    • (1997) J. Physiol. , vol.500 , Issue.3 , pp. 631-642
    • Ward, C.A.1    Giles, W.R.2
  • 109
    • 0025770664 scopus 로고
    • Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system
    • Weber, K. T., and Brilla, C. G. (1991). Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83, 1849-1865.
    • (1991) Circulation , vol.83 , pp. 1849-1865
    • Weber, K.T.1    Brilla, C.G.2
  • 112
    • 0017286235 scopus 로고
    • Triggered activity in cardiac muscle fibers of the simian mitral valve
    • Wit, A. L., and Cranefield, P. F. (1976). Triggered activity in cardiac muscle fibers of the simian mitral valve. Circ. Res. 38, 85-98.
    • (1976) Circ. Res. , vol.38 , pp. 85-98
    • Wit, A.L.1    Cranefield, P.F.2
  • 113
    • 26444473038 scopus 로고
    • Membrane resting and action potentials of single cardiac muscle fibers of the frog ventricle
    • Woodbury, L. A., Hecht, H. H., and Christopherson, A. R. (1951). Membrane resting and action potentials of single cardiac muscle fibers of the frog ventricle. Am. J. Physiol. 164, 307-318.
    • (1951) Am. J. Physiol. , vol.164 , pp. 307-318
    • Woodbury, L.A.1    Hecht, H.H.2    Christopherson, A.R.3
  • 114
    • 84865581574 scopus 로고    scopus 로고
    • Transient outward K+ current reduction prolongs action potentials and promotes afterdepolarisations: a dynamic-clamp study in human and rabbit cardiac atrial myocytes
    • Workman, A. J., Marshall, G. E., Rankin, A. C., Smith, G. L., and Dempster, J. (2012). Transient outward K+ current reduction prolongs action potentials and promotes afterdepolarisations: a dynamic-clamp study in human and rabbit cardiac atrial myocytes. J. Physiol. 590(17), 4289-4305.
    • (2012) J. Physiol. , vol.590 , Issue.17 , pp. 4289-4305
    • Workman, A.J.1    Marshall, G.E.2    Rankin, A.C.3    Smith, G.L.4    Dempster, J.5
  • 115
    • 0032127222 scopus 로고    scopus 로고
    • Characteristics of wave fronts during ventricular fibrillation in human hearts with dilated cardiomyopathy: role of increased fibrosis in the generation of reentry
    • Wu, T. J., Ong, J. J., Hwang, C., Lee, J. J., Fishbein, M. C., Czer, L., et al. (1998). Characteristics of wave fronts during ventricular fibrillation in human hearts with dilated cardiomyopathy: role of increased fibrosis in the generation of reentry. J. Am. Coll. Cardiol. 32, 187-196.
    • (1998) J. Am. Coll. Cardiol. , vol.32 , pp. 187-196
    • Wu, T.J.1    Ong, J.J.2    Hwang, C.3    Lee, J.J.4    Fishbein, M.C.5    Czer, L.6
  • 116
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn, T. A. (2007). Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Invest. 117, 524-529.
    • (2007) J. Clin. Invest. , vol.117 , pp. 524-529
    • Wynn, T.A.1
  • 117
    • 59649127713 scopus 로고    scopus 로고
    • Oxidative stress-induced afterdepolarizations and calmodulin kinase II signaling
    • Xie, L. H., Chen, F., Karagueuzian, H. S., and Weiss, J. N. (2009). Oxidative stress-induced afterdepolarizations and calmodulin kinase II signaling. Circ. Res. 104, 79-86.
    • (2009) Circ. Res. , vol.104 , pp. 79-86
    • Xie, L.H.1    Chen, F.2    Karagueuzian, H.S.3    Weiss, J.N.4
  • 118
    • 34548782679 scopus 로고    scopus 로고
    • Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue
    • doi: 10.1103/PhysRevLett.99.118101
    • Xie, Y., Hu, G., Sato, D., Weiss, J. N., Garfinkel, A., and Qu, Z. (2007). Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue. Phys. Rev. Lett. 99:118101. doi: 10.1103/PhysRevLett.99.118101
    • (2007) Phys. Rev. Lett. , vol.99 , pp. 118101
    • Xie, Y.1    Hu, G.2    Sato, D.3    Weiss, J.N.4    Garfinkel, A.5    Qu, Z.6
  • 119
    • 77956585767 scopus 로고    scopus 로고
    • So little source, so much sink: requirements for afterdepolarizations to propagate in tissue
    • Xie, Y., Sato, D., Garfinkel, A., Qu, Z., and Weiss, J. N. (2010). So little source, so much sink: requirements for afterdepolarizations to propagate in tissue. Biophys J. 99, 1408-1415.
    • (2010) Biophys J , vol.99 , pp. 1408-1415
    • Xie, Y.1    Sato, D.2    Garfinkel, A.3    Qu, Z.4    Weiss, J.N.5
  • 120
    • 0029002370 scopus 로고
    • Functional coupling between glycolysis and sarcoplasmic reticulum Ca2+ transport
    • Xu, K. Y., Zweier, J. L., and Becker, L. C. (1995). Functional coupling between glycolysis and sarcoplasmic reticulum Ca2+ transport. Circ. Res. 77, 88-97.
    • (1995) Circ. Res. , vol.77 , pp. 88-97
    • Xu, K.Y.1    Zweier, J.L.2    Becker, L.C.3
  • 121
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf, S., Sleight, P., Pogue, J., Bosch, J., Davies, R., and Dagenais, G. (2000). Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N. Engl. J. Med. 342, 145-153.
    • (2000) N. Engl. J. Med. , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 123
    • 78650845945 scopus 로고    scopus 로고
    • Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling
    • Zhao, Z., Fefelova, N., Shanmugam, M., Bishara, P., Babu, G. J., and Xie, L. H. (2011). Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling. J. Mol. Cell. Cardiol. 50, 128-136.
    • (2011) J. Mol. Cell. Cardiol. , vol.50 , pp. 128-136
    • Zhao, Z.1    Fefelova, N.2    Shanmugam, M.3    Bishara, P.4    Babu, G.J.5    Xie, L.H.6
  • 124
    • 84859756212 scopus 로고    scopus 로고
    • Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents
    • Zhao, Z., Wen, H., Fefelova, N., Allen, C., Baba, A., Matsuda, T., et al. (2012). Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents? Am. J. Physiol. Heart Circ. Physiol. 302, H1636-H1644.
    • (2012) Am. J. Physiol. Heart Circ. Physiol. , vol.302
    • Zhao, Z.1    Wen, H.2    Fefelova, N.3    Allen, C.4    Baba, A.5    Matsuda, T.6


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