Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: Predominant by Ca waves or Ca currents?

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Zhao, Zhenghang ^a,b   Wen, Hairuo ^a   Fefelova, Nadezhda ^a   Allen, Charelle ^a   Baba, Akemichi ^c   Matsuda, Toshio ^c   Xie, Lai Hua ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b XI'AN JIAOTONG UNIVERSITY   (China)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

adrenergic stimulation; Ca 2+wave; L type Ca 2+ current; Na Ca exchanger; Reactive oxygen species

Indexed keywords

CALCIUM; HYDROGEN PEROXIDE; ISOPRENALINE;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM SIGNALING; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; EARLY AFTERDEPOLARIZATION; HEART DEPOLARIZATION; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; VOLTAGE CLAMP; WAVEFORM;

ACTION POTENTIALS; ADRENERGIC BETA-AGONISTS; ANILINE COMPOUNDS; ANIMALS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM SIGNALING; ELECTROPHYSIOLOGICAL PHENOMENA; HEART VENTRICLES; HOMEODOMAIN PROTEINS; HYDROGEN PEROXIDE; ISOPROTERENOL; KINETICS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PHENYL ETHERS; RABBITS; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SODIUM-CALCIUM EXCHANGER;

EID: 84859756212     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00742.2011     Document Type: Article

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