Pirfenidone mitigates left ventricular fibrosis and dysfunction after myocardial infarction and reduces arrhythmias

Heart Rhythm

Volumn 7, Issue 10, 2010, Pages 1438-1445

  Nguyen, Duy T ^a   Ding, Chunhua ^a   Wilson, Emily ^a   Marcus, Gregory M ^a   Olgin, Jeffrey E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fibrosis; Optical mapping; Pirfenidone; Remodeling; Ventricular tachycardia

Indexed keywords

PIRFENIDONE; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG MECHANISM; ECHOCARDIOGRAPHY; ELECTROPHYSIOLOGY; HEART ARRHYTHMIA; HEART CONDUCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ECHOCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FIBROSIS; HEART CONDUCTION SYSTEM; HEART VENTRICLES; MALE; MYOCARDIAL INFARCTION; NEURAL CONDUCTION; PYRIDONES; RATS; RATS, SPRAGUE-DAWLEY; TACHYCARDIA, VENTRICULAR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 77957255499     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2010.04.030     Document Type: Article

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