S1P1 inhibits sprouting angiogenesis during vascular development

Development (Cambridge)

Volumn 139, Issue 20, 2012, Pages 3859-3869

  Shoham, Adi Ben ^a   Malkinson, Guy ^a   Krief, Sharon ^a   Shwartz, Yulia ^a   Ely, Yona ^a   Ferrara, Napoleone ^b   Yaniv, Karina ^a   Zelzer, Elazar ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b GENENTECH INC   (United States)

Author keywords

Angiogenesis; Caudal vein plexus; Endothelial cell; Filopodia; Intersegmental vessels; Limb vasculature; Mouse; Sphingosine 1 phosphate receptor 1 (S1P1); Sprouting; Vascular remodeling; Zebrafish

Indexed keywords

SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CELL INTERACTION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; GENE; GENE EXPRESSION; GENE INTERACTION; GENETIC CONSERVATION; IN VITRO STUDY; LIMB DEVELOPMENT; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SIP1 GENE; VEGFA GENE; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; BLOOD VESSEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PRENATAL DEVELOPMENT; TRANSGENIC MOUSE;

DANIO RERIO;

ANIMALS; BLOOD VESSELS; EMBRYO, MAMMALIAN; ENDOTHELIAL CELLS; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTORS, LYSOSPHINGOLIPID; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

EID: 84866487978     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.078550     Document Type: Article

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