Targeting the nuclear hormone receptor RORγt for the treatment of autoimmune and inflammatory disorders

Annual Reports in Medicinal Chemistry

Volumn 48, Issue , 2013, Pages 169-182

  Dhar, T G Murali ^a   Zhao, Qihong ^a   Markby, David W ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b EXELIXIS INC   (United States)

Author keywords

Antagonist; Autoimmune; IL 17; IL 23; Inflammatory disease; Retinoic acid related orphan receptor; ROR t

Indexed keywords

BRODALUMAB; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HORMONE RECEPTOR AFFECTING AGENT; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 6; INTERLEUKIN 9; IXEKIZUMAB; LIVER RECEPTOR HOMOLOG 1; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; NUCLEAR RECEPTOR COACTIVATOR 2; RETINOIC ACID RELATED ORPHAN RECEPTOR GAMMA; SC 89732; SC 92366; SECUKINUMAB; SR 1001; SR 1555; SR 2211; SR 9805; STROMELYSIN; SULFONAMIDE; TRIFLUMIZOLE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; URSOLIC ACID; USTEKINUMAB;

ARTICLE; AUTOIMMUNE DISEASE; AUTOINFLAMMATORY DISEASE; CELL PROLIFERATION; DISEASE MODEL; DISEASE SEVERITY; GENE EXPRESSION; HUMAN; INCIDENCE; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

EID: 84884150762     PISSN: 00657743     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-417150-3.00012-0     Document Type: Chapter

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