메뉴 건너뛰기




Volumn 20, Issue 3, 2012, Pages 488-497

The retinoic acid receptor-related orphan nuclear receptor γ1 (RORγ1): A novel player determinant of insulin sensitivity in morbid obesity

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; MESSENGER RNA; ORPHAN NUCLEAR RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RETINOIC ACID RECEPTOR RELATED ORPHAN NUCLEAR RECEPTOR GAMMA 1; UNCLASSIFIED DRUG;

EID: 84857665826     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.267     Document Type: Article
Times cited : (16)

References (36)
  • 1
    • 33745387612 scopus 로고    scopus 로고
    • Overview of retinoid metabolism and function
    • Blomhoff R, Blomhoff HK. Overview of retinoid metabolism and function. J Neurobiol 2006;66:606-630.
    • (2006) J Neurobiol , vol.66 , pp. 606-630
    • Blomhoff, R.1    Blomhoff, H.K.2
  • 2
    • 0026515185 scopus 로고
    • Retinoids and retinoid-binding protein expression in rat adipocytes
    • Tsutsumi C, Okuno M, Tannous L et al. Retinoids and retinoid-binding protein expression in rat adipocytes. J Biol Chem 1992;267:1805-1810.
    • (1992) J Biol Chem , vol.267 , pp. 1805-1810
    • Tsutsumi, C.1    Okuno, M.2    Tannous, L.3
  • 3
    • 34247150540 scopus 로고    scopus 로고
    • Regulation of adipocyte differentiation by PEGylated all-trans retinoic acid: Reduced cytotoxicity and attenuated lipid accumulation
    • Moon HS, Guo DD, Song HH et al. Regulation of adipocyte differentiation by PEGylated all-trans retinoic acid: reduced cytotoxicity and attenuated lipid accumulation. J Nutr Biochem 2007;18:322-331.
    • (2007) J Nutr Biochem , vol.18 , pp. 322-331
    • Moon, H.S.1    Guo, D.D.2    Song, H.H.3
  • 4
    • 17444442152 scopus 로고    scopus 로고
    • Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
    • Boehm MF, Mondon CE, Nadzan AM et al. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 1997;386:407-410.
    • (1997) Nature , vol.386 , pp. 407-410
    • Boehm, M.F.1    Mondon, C.E.2    Nadzan, A.M.3
  • 5
    • 0141730390 scopus 로고    scopus 로고
    • All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta
    • Stehlin-Gaon C, Willmann D, Zeyer D et al. All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol 2003;10:820-825.
    • (2003) Nat Struct Biol , vol.10 , pp. 820-825
    • Stehlin-Gaon, C.1    Willmann, D.2    Zeyer, D.3
  • 6
    • 0030605240 scopus 로고    scopus 로고
    • Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element
    • Medvedev A, Yan ZH, Hirose T, Giguère V, Jetten AM. Cloning of a cDNA encoding the murine orphan receptor RZR/ROR gamma and characterization of its response element. Gene 1996;181:199-206.
    • (1996) Gene , vol.181 , pp. 199-206
    • Medvedev, A.1    Yan, Z.H.2    Hirose, T.3    Giguère, V.4    Jetten, A.M.5
  • 7
    • 35548949049 scopus 로고    scopus 로고
    • Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism
    • Kang HS, Angers M, Beak JY et al. Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism. Physiol Genomics 2007;31:281-294.
    • (2007) Physiol Genomics , vol.31 , pp. 281-294
    • Kang, H.S.1    Angers, M.2    Beak, J.Y.3
  • 8
    • 0028957315 scopus 로고
    • Determinants of target gene specificity for ROR alpha 1: Monomeric DNA binding by an orphan nuclear receptor
    • Giguère V, McBroom LD, Flock G. Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor. Mol Cell Biol 1995;15:2517-2526.
    • (1995) Mol Cell Biol , vol.15 , pp. 2517-2526
    • Giguère, V.1    McBroom, L.D.2    Flock, G.3
  • 9
    • 0031902221 scopus 로고    scopus 로고
    • Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells
    • Austin S, Medvedev A, Yan ZH et al. Induction of the nuclear orphan receptor RORgamma during adipocyte differentiation of D1 and 3T3-L1 cells. Cell Growth Differ 1998;9:267-276.
    • (1998) Cell Growth Differ , vol.9 , pp. 267-276
    • Austin, S.1    Medvedev, A.2    Yan, Z.H.3
  • 10
    • 20444475450 scopus 로고    scopus 로고
    • The transcriptional basis of adipocyte development
    • Rosen ED. The transcriptional basis of adipocyte development. Prostaglandins Leukot Essent Fatty Acids 2005;73:31-34.
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 31-34
    • Rosen, E.D.1
  • 12
    • 66849099394 scopus 로고    scopus 로고
    • Retinoid-related orphan receptors (RORs): Critical roles in development, immunity, circadian rhythm, and cellular metabolism
    • Jetten AM. Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism. Nucl Recept Signal 2009;7:e003.
    • (2009) Nucl Recept Signal , vol.7
    • Jetten, A.M.1
  • 13
    • 18644384149 scopus 로고    scopus 로고
    • Genetic analysis of adipogenesis through peroxisome proliferator- activated receptor gamma isoforms
    • Mueller E, Drori S, Aiyer A et al. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. J Biol Chem 2002;277:41925-41930.
    • (2002) J Biol Chem , vol.277 , pp. 41925-41930
    • Mueller, E.1    Drori, S.2    Aiyer, A.3
  • 14
    • 34848869740 scopus 로고    scopus 로고
    • Upregulation of peroxisome proliferatoractivated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure
    • Gastaldi G, Russell A, Golay A et al. Upregulation of peroxisome proliferatoractivated receptor gamma coactivator gene (PGC1A) during weight loss is related to insulin sensitivity but not to energy expenditure. Diabetologia 2007;50:2348-2355.
    • (2007) Diabetologia , vol.50 , pp. 2348-2355
    • Gastaldi, G.1    Russell, A.2    Golay, A.3
  • 15
    • 18244363982 scopus 로고    scopus 로고
    • Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
    • Maeda K, Cao H, Kono K et al. Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab 2005;1:107-119.
    • (2005) Cell Metab , vol.1 , pp. 107-119
    • Maeda, K.1    Cao, H.2    Kono, K.3
  • 16
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW et al. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998;92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3
  • 17
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer SR. Transcriptional control of adipocyte formation. Cell Metab 2006;4:263-273.
    • (2006) Cell Metab , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 18
    • 33749145610 scopus 로고    scopus 로고
    • Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in non-E3/E3 patients with the metabolic syndrome
    • Cardona F, Morcillo S, Gonzalo-Marín M et al. Pro12Ala sequence variant of the PPARG gene is associated with postprandial hypertriglyceridemia in non-E3/E3 patients with the metabolic syndrome. Clin Chem 2006;52:1920-1925.
    • (2006) Clin Chem , vol.52 , pp. 1920-1925
    • Cardona, F.1    Morcillo, S.2    Gonzalo-Marín, M.3
  • 20
    • 0037337314 scopus 로고    scopus 로고
    • Calreticulin-melatonin. An unexpected relationship
    • Macías M, Escames G, Leon J et al. Calreticulin-melatonin. An unexpected relationship. Eur J Biochem 2003;270:832-840.
    • (2003) Eur J Biochem , vol.270 , pp. 832-840
    • Macías, M.1    Escames, G.2    Leon, J.3
  • 21
    • 0142056953 scopus 로고    scopus 로고
    • Corepressor excess shifts the two-side chain vitamin D analog Gemini from an agonist to an inverse agonist of the vitamin D receptor
    • Gonzalez MM, Samenfeld P, Peräkylä M, Carlberg C. Corepressor excess shifts the two-side chain vitamin D analog Gemini from an agonist to an inverse agonist of the vitamin D receptor. Mol Endocrinol 2003;17:2028-2038.
    • (2003) Mol Endocrinol , vol.17 , pp. 2028-2038
    • Gonzalez, M.M.1    Samenfeld, P.2    Peräkylä, M.3    Carlberg, C.4
  • 22
    • 0035124840 scopus 로고    scopus 로고
    • Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity
    • Cousin B, André M, Casteilla L, Pénicaud L. Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity. J Cell Physiol 2001;186:380-386.
    • (2001) J Cell Physiol , vol.186 , pp. 380-386
    • Cousin, B.1    André, M.2    Casteilla, L.3    Pénicaud, L.4
  • 23
    • 0141730390 scopus 로고    scopus 로고
    • All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta
    • Stehlin-Gaon C, Willmann D, Zeyer D et al. All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol 2003;10:820-825.
    • (2003) Nat Struct Biol , vol.10 , pp. 820-825
    • Stehlin-Gaon, C.1    Willmann, D.2    Zeyer, D.3
  • 24
    • 0031037988 scopus 로고    scopus 로고
    • Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription
    • Schwarz EJ, Reginato MJ, Shao D, Krakow SL, Lazar MA. Retinoic acid blocks adipogenesis by inhibiting C/EBPbeta-mediated transcription. Mol Cell Biol 1997;17:1552-1561.
    • (1997) Mol Cell Biol , vol.17 , pp. 1552-1561
    • Schwarz, E.J.1    Reginato, M.J.2    Shao, D.3    Krakow, S.L.4    Lazar, M.A.5
  • 25
    • 34249977327 scopus 로고    scopus 로고
    • Retinaldehyde represses adipogenesis and diet-induced obesity
    • Ziouzenkova O, Orasanu G, Sharlach M et al. Retinaldehyde represses adipogenesis and diet-induced obesity. Nat Med 2007;13:695-702.
    • (2007) Nat Med , vol.13 , pp. 695-702
    • Ziouzenkova, O.1    Orasanu, G.2    Sharlach, M.3
  • 26
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang Q, Graham TE, Mody N et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005;436:356-362.
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 27
    • 34247844461 scopus 로고    scopus 로고
    • The effect of genetic variation of the retinoic acid receptor-related orphan receptor C gene on fatness in cattle
    • Barendse W, Bunch RJ, Kijas JW, Thomas MB. The effect of genetic variation of the retinoic acid receptor-related orphan receptor C gene on fatness in cattle. Genetics 2007;175:843-853.
    • (2007) Genetics , vol.175 , pp. 843-853
    • Barendse, W.1    Bunch, R.J.2    Kijas, J.W.3    Thomas, M.B.4
  • 28
    • 0034770707 scopus 로고    scopus 로고
    • Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals
    • Fisher RM, Eriksson P, Hoffstedt J et al. Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals. Diabetologia 2001;44:1268-1273.
    • (2001) Diabetologia , vol.44 , pp. 1268-1273
    • Fisher, R.M.1    Eriksson, P.2    Hoffstedt, J.3
  • 29
    • 33745305433 scopus 로고    scopus 로고
    • Insulin signaling in human visceral and subcutaneous adipose tissue in vivo
    • Laviola L, Perrini S, Cignarelli A et al. Insulin signaling in human visceral and subcutaneous adipose tissue in vivo. Diabetes 2006;55:952-961.
    • (2006) Diabetes , vol.55 , pp. 952-961
    • Laviola, L.1    Perrini, S.2    Cignarelli, A.3
  • 30
    • 0033857387 scopus 로고    scopus 로고
    • Treatment of insulin resistance with peroxisome proliferatoractivated receptor gamma agonists
    • Olefsky JM. Treatment of insulin resistance with peroxisome proliferatoractivated receptor gamma agonists. J Clin Invest 2000;106:467-472.
    • (2000) J Clin Invest , vol.106 , pp. 467-472
    • Olefsky, J.M.1
  • 32
    • 57349170893 scopus 로고    scopus 로고
    • Cellular retinol-binding protein type III is a PPARgamma target gene and plays a role in lipid metabolism
    • Zizola CF, Schwartz GJ, Vogel S. Cellular retinol-binding protein type III is a PPARgamma target gene and plays a role in lipid metabolism. Am J Physiol Endocrinol Metab 2008;295:E1358-E1368.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Zizola, C.F.1    Schwartz, G.J.2    Vogel, S.3
  • 33
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 2003;144:2201-2207.
    • (2003) Endocrinology , vol.144 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 34
    • 22544456280 scopus 로고    scopus 로고
    • Structural determinants of the agonistindependent association of human peroxisome proliferator-activated receptors with coactivators
    • Molnár F, Matilainen M, Carlberg C. Structural determinants of the agonistindependent association of human peroxisome proliferator-activated receptors with coactivators. J Biol Chem 2005;280:26543-26556.
    • (2005) J Biol Chem , vol.280 , pp. 26543-26556
    • Molnár, F.1    Matilainen, M.2    Carlberg, C.3
  • 35
    • 38649123072 scopus 로고    scopus 로고
    • Conserved metabolic regulatory functions of sirtuins
    • Schwer B, Verdin E. Conserved metabolic regulatory functions of sirtuins. Cell Metab 2008;7:104-112.
    • (2008) Cell Metab , vol.7 , pp. 104-112
    • Schwer, B.1    Verdin, E.2
  • 36
    • 34247259630 scopus 로고    scopus 로고
    • Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
    • Gerhart-Hines Z, Rodgers JT, Bare O et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J 2007;26:1913-1923.
    • (2007) EMBO J , vol.26 , pp. 1913-1923
    • Gerhart-Hines, Z.1    Rodgers, J.T.2    Bare, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.