Restoration of PTEN activity decreases metastases in an orthotopic model of colon cancer

Journal of Surgical Research

Volumn 184, Issue 2, 2013, Pages 755-760

  Chowdhury, Sanjib ^a   Ongchin, Melanie ^b   Wan, Guanghua ^c   Sharratt, Elizabeth ^d   Brattain, Michael G ^a   Rajput, Ashwani ^c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Colorectal cancer; Metastases; PI3Kinase; PTEN

Indexed keywords

GREEN FLUORESCENT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER TRANSPLANTATION; CELL CLONE; CELL HOMING; CELL LABELING; COLON CANCER; CONTROLLED STUDY; ENZYME REACTIVATION; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER METASTASIS; LOSS OF FUNCTION MUTATION; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; TUMOR INVASION;

COLORECTAL CANCER; METASTASES; PI3KINASE; PTEN;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; HETEROGRAFTS; HUMANS; INCIDENCE; LIVER NEOPLASMS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 84883861499     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.03.035     Document Type: Article

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