Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model

Journal of Surgical Research

Volumn 147, Issue 2, 2008, Pages 276-281

  Rajput, Ashwani ^a,b   Dominguez San Martin, Ivan ^b   Rose, Rebecca ^b   Beko, Alexander ^a   LeVea, Charles ^a   Sharratt, Elizabeth ^a   Mazurchuk, Richard ^a   Hoffman, Robert M ^c,d   Brattain, Michael G ^a   Wang, Jing ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c ANTICANCER INC   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

colon cancer; metastasis; orthotopic model

Indexed keywords

EOSIN; GREEN FLUORESCENT PROTEIN; HEMATOXYLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INVASION; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG METASTASIS; MALE; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; SURGICAL TECHNIQUE; TUMOR GROWTH;

ANIMALS; CARCINOMA; COLONIC NEOPLASMS; HCT116 CELLS; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS, EXPERIMENTAL;

EID: 43549116099     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2007.04.021     Document Type: Article

References (31)

1. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2006. CA Cancer J Clin 56 (2006) 106
2. Steeg P.S. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 3 (2003) 55
3. Fidler I.J. Critical determinants of metastasis. Semin Cancer Biol 12 (2002) 89
4. Jiang D., Yang H., Willson J.K., et al. Autocrine transforming growth factor alpha provides a growth advantage to malignant cells by facilitating re-entry into the cell cycle from suboptimal growth states. J Biol Chem 273 (1998) 31471
5. Howell G.M., Humphrey L.E., Awwad R.A., et al. Aberrant regulation of transforming growth factor-alpha during the establishment of growth arrest and quiescence of growth factor independent cells. J Biol Chem 273 (1998) 9214
6. Sawhney R.S., Zhou G.H., Humphrey L.E., et al. Differences in sensitivity of biological functions mediated by epidermal growth factor receptor activation with respect to endogenous and exogenous ligands. J Biol Chem 277 (2002) 75
7. Awwad R.A., Sergina N., Yang H., et al. The role of transforming growth factor alpha in determining growth factor independence. Cancer Res 63 (2003) 4731
8. Wang J., Sun L., Myeroff L., et al. Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. J Biol Chem 270 (1995) 22044
9. Schlechte W., Brattain M., and Boyd D. Invasion of extracellular matrix by cultured colon cancer cells: Dependence on urokinase receptor display. Cancer Commun 2 (1990) 173
10. Boyd D.D., Levine A.E., Brattain D.E., et al. Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose. Cancer Res 48 (1988) 2469
11. Fu X.Y., Besterman J.M., Monosov A., et al. Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens. Proc Nat Acad Sci USA 88 (1991) 9345
12. Fu X., Herrera H., Kubota T., et al. Extensive liver metastasis from human colon cancer in nude and scid mice after orthotopic onplantation of histologically-intact human colon carcinoma tissue. Anticancer Res 12 (1992) 1395
13. Sun F.X., Sasson A.R., Jiang P., et al. An ultra-metastatic model of human colon cancer in nude mice. Clin Exp Metastasis 17 (1999) 41
14. Rashidi B., Sun F.X., Jiang P., et al. A nude mouse model of massive liver and lymph node metastasis of human colon cancer. Anticancer Res 20 (2000) 715
15. Bouvet M., Wang J., Nardin S.R., et al. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res 62 (2002) 1534
16. Katz M.H., Takimoto S., Spivack D., et al. A novel red fluorescent protein orthotopic pancreatic cancer model for the preclinical evaluation of chemotherapeutics. J Surg Res 113 (2003) 151
17. Bouvet M., Spernyak J., Katz M.H., et al. High correlation of whole body fluorescent protein imaging and MR imaging on an orthotopic model of pancreatic cancer. Cancer Res 65 (2005) 9829
18. Saltz L.B., Meropol N.J., Loehrer Sr. P.J., et al. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 22 (2004) 1201
19. Cunningham D., Humblet Y., Siena S., et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351 (2004) 337
20. Perez-Soler R., Chachoua A., Hammond L.A., et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 22 (2004) 3238
21. Hoffman R.M. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 5 (2005) 796
22. Chambers A.F., Groom A.C., and MacDonald I.C. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2 (2002) 563
23. Chambers A.F., Naumov G.N., Varghese H.J., et al. Critical steps in hematogenous metastasis: An overview. Surg Oncol Clin N Am 10 (2001) 243
24. Chambers A.F., Naumov G.N., Vantyghem S.A., et al. Molecular biology of breast cancer metastasis. Clinical implications of experimental studies on metastatic inefficiency. Breast Cancer Res 2 (2000) 400
25. Strauli P., and Weiss L. Cell locomation and tumor penetration. Report on a workshop of the EORTC cell surface project group. Eur J Cancer 13 (1977) 1
26. Nabeshima K., Inoue T., Shimao Y., et al. Cohort migration of carcinoma cells: differentiated colorectal carcinoma cells move as coherent cell clusters or sheets. Histol Histopathol 14 (1999) 1183
27. Shimao Y., Nabeshima K., Inoue T., et al. Role of fibroblasts in HGF/SF-induced cohort migration of human colorectal carcinoma cells: Fibroblasts stimulate migration associated with increased fibronectin production via up-regulated TGF-beta1. Int J Cancer 82 (1999) 449
28. Hoffman R.M. Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy. Methods Mol Med 111 (2005) 297
29. Christiansen J.J., and Rajasekaran A.K. Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 66 (2006) 8319
30. Thiery J.P. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 15 (2003) 740
31. Tarin D, Thompson EW, Newgreen DF. The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 65:5996; discussion 2005;6000.