메뉴 건너뛰기




Volumn 42, Issue 7, 2011, Pages 584-588

High Level of PTEN Expression Is Associated with Low-grade Liver Metastasis and Satisfactory Patient Survival in Pancreatic Cancer

Author keywords

Liver metastasis; Pancreatic cancer; Phosphatase and tensin homolog

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84862968354     PISSN: 01884409     EISSN: 18735487     Source Type: Journal    
DOI: 10.1016/j.arcmed.2011.10.008     Document Type: Article
Times cited : (7)

References (25)
  • 2
    • 79952382550 scopus 로고    scopus 로고
    • Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer
    • Bao B., Ali S., Kong D., et al. Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. PLoS One 2011, 6:e17850.
    • (2011) PLoS One , vol.6
    • Bao, B.1    Ali, S.2    Kong, D.3
  • 3
    • 19944427667 scopus 로고    scopus 로고
    • Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer
    • Thomas G.V., Horvath S., Smith B.L., et al. Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer. Clin Cancer Res 2004, 10:8351-8356.
    • (2004) Clin Cancer Res , vol.10 , pp. 8351-8356
    • Thomas, G.V.1    Horvath, S.2    Smith, B.L.3
  • 4
    • 10844282781 scopus 로고    scopus 로고
    • Dominant negative inhibitors of signaling through the phosphoinositol 3-kinase pathway for gene therapy of pancreatic cancer
    • Stoll V., Calleja V., Vassaux G., et al. Dominant negative inhibitors of signaling through the phosphoinositol 3-kinase pathway for gene therapy of pancreatic cancer. Gut 2005, 54:109-116.
    • (2005) Gut , vol.54 , pp. 109-116
    • Stoll, V.1    Calleja, V.2    Vassaux, G.3
  • 5
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully M., You H., Levine A.J., et al. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer 2006, 6:184-192.
    • (2006) Nat Rev Cancer , vol.6 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3
  • 6
    • 76749088993 scopus 로고    scopus 로고
    • TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells
    • Chow J.Y., Ban M., Wu H.L., et al. TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells. Am J Physiol Gastrointest Liver Physiol 2010, 298:G275-G282.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298
    • Chow, J.Y.1    Ban, M.2    Wu, H.L.3
  • 7
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T., Dixon J.E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998, 273:13375-13378.
    • (1998) J Biol Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 8
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Di Cristofano A., Pandolfi P.P. The multiple roles of PTEN in tumor suppression. Cell 2000, 100:387-390.
    • (2000) Cell , vol.100 , pp. 387-390
    • Di Cristofano, A.1    Pandolfi, P.P.2
  • 9
    • 0035835824 scopus 로고    scopus 로고
    • PTEN: life as a tumor suppressor
    • Simpson L., Parsons R. PTEN: life as a tumor suppressor. Exp Cell Res 2001, 264:29-41.
    • (2001) Exp Cell Res , vol.264 , pp. 29-41
    • Simpson, L.1    Parsons, R.2
  • 10
    • 0032006029 scopus 로고    scopus 로고
    • Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors
    • Okami K., Wu L., Riggins G., et al. Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. Cancer Res 1998, 58:509-511.
    • (1998) Cancer Res , vol.58 , pp. 509-511
    • Okami, K.1    Wu, L.2    Riggins, G.3
  • 11
    • 36148968456 scopus 로고    scopus 로고
    • RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells
    • Chow J.Y., Quach K.T., Cabrera B.L., et al. RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells. Carcinogenesis 2007, 28:2321-2327.
    • (2007) Carcinogenesis , vol.28 , pp. 2321-2327
    • Chow, J.Y.1    Quach, K.T.2    Cabrera, B.L.3
  • 12
    • 77956925475 scopus 로고    scopus 로고
    • PTEN loss accelerates KrasG12D-induced pancreatic cancer development
    • Hill R., Calvopina J.H., Kim C., et al. PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Res 2010, 70:7114-7124.
    • (2010) Cancer Res , vol.70 , pp. 7114-7124
    • Hill, R.1    Calvopina, J.H.2    Kim, C.3
  • 14
    • 77951765458 scopus 로고    scopus 로고
    • Radiotherapy in the management of unresectable locally advanced pancreatic cancer: a survey of the current UK practice of clinical oncologists
    • Saleem A., Jackson A., Mukherjee S., et al. Radiotherapy in the management of unresectable locally advanced pancreatic cancer: a survey of the current UK practice of clinical oncologists. Clin Oncol (R Coll Radiol) 2010, 22:257-260.
    • (2010) Clin Oncol (R Coll Radiol) , vol.22 , pp. 257-260
    • Saleem, A.1    Jackson, A.2    Mukherjee, S.3
  • 15
    • 0032985541 scopus 로고    scopus 로고
    • Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database
    • Sener S.F., Fremgen A., Menck H.R., et al. Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database. J Am Coll Surg 1999, 189:1-7.
    • (1999) J Am Coll Surg , vol.189 , pp. 1-7
    • Sener, S.F.1    Fremgen, A.2    Menck, H.R.3
  • 16
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Tamura M., Gu J., Matsumoto K., et al. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998, 280:1614-1617.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3
  • 17
    • 77951568703 scopus 로고    scopus 로고
    • Phosphoinositide signalling in cancer: beyond PI3K and PTEN
    • Bunney T.D., Katan M. Phosphoinositide signalling in cancer: beyond PI3K and PTEN. Nat Rev Cancer 2010, 10:342-352.
    • (2010) Nat Rev Cancer , vol.10 , pp. 342-352
    • Bunney, T.D.1    Katan, M.2
  • 18
    • 58149354425 scopus 로고    scopus 로고
    • Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival
    • Sawai H., Yasuda A., Ochi N., et al. Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival. BMC Gastroenterol 2008, 8:56.
    • (2008) BMC Gastroenterol , vol.8 , pp. 56
    • Sawai, H.1    Yasuda, A.2    Ochi, N.3
  • 19
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering B.M., Coffer P.J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995, 376:599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 20
    • 24744459442 scopus 로고    scopus 로고
    • NF-kappaB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis invivo
    • Jones R.G., Saibil S.D., Pun J.M., et al. NF-kappaB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis invivo. J Immunol 2005, 175:3790-3799.
    • (2005) J Immunol , vol.175 , pp. 3790-3799
    • Jones, R.G.1    Saibil, S.D.2    Pun, J.M.3
  • 21
    • 42049109067 scopus 로고    scopus 로고
    • TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells
    • Chow J.Y., Dong H., Quach K.T., et al. TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells. Am J Physiol Gastrointest Liver Physiol 2008, 294:G899-G905.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Chow, J.Y.1    Dong, H.2    Quach, K.T.3
  • 22
    • 74049134054 scopus 로고    scopus 로고
    • PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells
    • Ma J., Sawai H., Ochi N., et al. PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells. Mol Cell Biochem 2009, 331:161-171.
    • (2009) Mol Cell Biochem , vol.331 , pp. 161-171
    • Ma, J.1    Sawai, H.2    Ochi, N.3
  • 23
    • 0042316755 scopus 로고    scopus 로고
    • PTEN: one gene, many syndromes
    • Eng C. PTEN: one gene, many syndromes. Hum Mutat 2003, 22:183-198.
    • (2003) Hum Mutat , vol.22 , pp. 183-198
    • Eng, C.1
  • 24
    • 77950466568 scopus 로고    scopus 로고
    • Effects of activated PPARgamma on the expression of PTEN gene in pancreatic cancer cells
    • Bai M.H., Ma H.B., Wang X.J. Effects of activated PPARgamma on the expression of PTEN gene in pancreatic cancer cells. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2008, 24:717-720.
    • (2008) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi , vol.24 , pp. 717-720
    • Bai, M.H.1    Ma, H.B.2    Wang, X.J.3
  • 25
    • 44649107718 scopus 로고    scopus 로고
    • Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis
    • Tao J., Xiong J., Li T. Correlation between protein expression of PTEN in human pancreatic cancer and the proliferation, infiltration, metastasis and prognosis. J Huazhong Univ Sci Technolog Med Sci 2006, 26:444-447.
    • (2006) J Huazhong Univ Sci Technolog Med Sci , vol.26 , pp. 444-447
    • Tao, J.1    Xiong, J.2    Li, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.