메뉴 건너뛰기




Volumn 455, Issue 1-2, 2013, Pages 365-373

Bioavailability enhancement of glucosamine hydrochloride by chitosan

Author keywords

Bioavailability; Caco 2 cell model; Chitosan; Glucosamine; Permeability

Indexed keywords

CHITOSAN; GLUCOSAMINE;

EID: 84883851893     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.06.055     Document Type: Article
Times cited : (32)

References (67)
  • 1
    • 0036708636 scopus 로고    scopus 로고
    • The bioavailability and pharmacokinetics of glucosamine hydrochloride and low molecular weight chondroitin sulfate after single and multiple doses to beagle dogs
    • Adebowale, A., Du, J.P., Liang, Z.M., Leslie, J.L., Eddington, N.D., 2002. The bioavailability and pharmacokinetics of glucosamine hydrochloride and low molecular weight chondroitin sulfate after single and multiple doses to beagle dogs. Biopharm. Drug Dispos. 23, 217-225.
    • (2002) Biopharm. Drug Dispos. , vol.23 , pp. 217-225
    • Adebowale, A.1    Du, J.P.2    Liang, Z.M.3    Leslie, J.L.4    Eddington, N.D.5
  • 2
    • 79961164393 scopus 로고    scopus 로고
    • The glucosamine controversy; a pharmacokinetic issue
    • Aghazadeh-Habashi, A., Jamali, F., 2011. The glucosamine controversy; a pharmacokinetic issue. J. Pharm. Pharm. Sci. 14, 264-273.
    • (2011) J. Pharm. Pharm. Sci. , vol.14 , pp. 264-273
    • Aghazadeh-Habashi, A.1    Jamali, F.2
  • 4
    • 0027173738 scopus 로고
    • Epithelial transport of drugs in cell culture. VIII: Effects of sodium dodecyl sulfate on cell membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells
    • DOI 10.1002/jps.2600820412
    • Anderberg, E.K., Artursson, P., 1993. Epithelial transport of drugs in cell-culture. VIII: effects of sodium dodecyl-sulfate on cell-membrane and tight junction permeability in human intestinal epithelial (Caco-2) cells. J. Pharm. Sci. 82, 392-398. (Pubitemid 23150434)
    • (1993) Journal of Pharmaceutical Sciences , vol.82 , Issue.4 , pp. 392-398
    • Anderberg, E.K.1    Artursson, P.2
  • 5
    • 0028071051 scopus 로고
    • Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
    • DOI 10.1023/A:1018967116988
    • Artursson, P., Lindmark, T., Davis, S.S., Illum, L., 1994. Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm. Res. 11, 1358-1361. (Pubitemid 24287420)
    • (1994) Pharmaceutical Research , vol.11 , Issue.9 , pp. 1358-1361
    • Artursson, P.1    Lindmark, T.2    Davis, S.S.3    Illum, L.4
  • 6
    • 0035286778 scopus 로고    scopus 로고
    • Caco-2 monolayers in experimental and theoretical predictions of drug transport
    • Artursson, P., Palm, K., Luthman, K., 2001. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv. Drug Deliv. Rev. 46, 27-43.
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 27-43
    • Artursson, P.1    Palm, K.2    Luthman, K.3
  • 7
    • 84857617880 scopus 로고    scopus 로고
    • Absorption enhancers: Applications and advances
    • Aungst, B.J., 2012. Absorption enhancers: applications and advances. AAPS J. 14, 10-18.
    • (2012) AAPS J. , vol.14 , pp. 10-18
    • Aungst, B.J.1
  • 8
    • 11844288271 scopus 로고    scopus 로고
    • Influence of molecular weight on oral absorption of water soluble chitosans
    • DOI 10.1016/j.jconrel.2004.10.012, PII S0168365904004936
    • Chae, S.Y., Jang, M.K., Nah, J.W., 2005. Influence of molecular weight on oral absorption of water soluble chitosans. J. Control. Release 102, 383-394. (Pubitemid 40093761)
    • (2005) Journal of Controlled Release , vol.102 , Issue.2 , pp. 383-394
    • Chae, S.Y.1    Jang, M.-K.2    Nah, J.-W.3
  • 9
    • 0032917517 scopus 로고    scopus 로고
    • Effect of chitosan on epithelial permeability and structure
    • DOI 10.1016/S0378-5173(99)00030-7, PII S0378517399000307
    • Dodane, V., Khan, M.A., Merwin, J.R., 1999. Effect of chitosan on epithelial permeability and structure. Int. J. Pharm. 182, 21-32. (Pubitemid 29229791)
    • (1999) International Journal of Pharmaceutics , vol.182 , Issue.1 , pp. 21-32
    • Dodane, V.1    Amin, K.M.2    Merwin, J.R.3
  • 13
    • 84861202381 scopus 로고    scopus 로고
    • In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein
    • Fong, Y.K., Li, C.R., Wo, S.K., Wang, S., Zhou, L., Zhang, L., Lin, G., Zuo, Z., 2012. In vitro and in situ evaluation of herb-drug interactions during intestinal metabolism and absorption of baicalein. J. Ethnopharmacol. 141, 742-753.
    • (2012) J. Ethnopharmacol. , vol.141 , pp. 742-753
    • Fong, Y.K.1    Li, C.R.2    Wo, S.K.3    Wang, S.4    Zhou, L.5    Zhang, L.6    Lin, G.7    Zuo, Z.8
  • 14
    • 77954627376 scopus 로고    scopus 로고
    • Introduction: Claudins, tight junctions, and the paracellular barrier
    • Alan, S.L.Y. (Ed.), Academic Press, London, UK, (Chapter 1)
    • Furuse, M., 2010. Introduction: claudins, tight junctions, and the paracellular barrier. In: Alan, S.L.Y. (Ed.), Current Topics in Membranes, vol. 65. Academic Press, London, UK, pp. 1-19 (Chapter 1).
    • (2010) Current Topics in Membranes , vol.65 , pp. 1-19
    • Furuse, M.1
  • 15
    • 44749091974 scopus 로고    scopus 로고
    • Improvement of intestinal absorption of insulin and water-soluble macromolecular compounds by chitosan oligomers in rats
    • Gao, Y., He, L., Katsumi, H., Sakane, T., Fujita, T., Yamamoto, A., 2008. Improvement of intestinal absorption of insulin and water-soluble macromolecular compounds by chitosan oligomers in rats. Int. J. Pharm. 359, 70-78.
    • (2008) Int. J. Pharm. , vol.359 , pp. 70-78
    • Gao, Y.1    He, L.2    Katsumi, H.3    Sakane, T.4    Fujita, T.5    Yamamoto, A.6
  • 16
    • 0346999481 scopus 로고    scopus 로고
    • Influence of chitosans on permeability of human intestinal epithelial (Caco-2) cells: The effect of molecular weight, degree of deacetylation and exposure time
    • Peter, M.G., Domard, A., Muzzarelli, R.A.A. (Eds.), Universität Potsdam, Schmergow, Germany
    • Holme, H.K., Hagen, A., Dornish, M., 2000. Influence of chitosans on permeability of human intestinal epithelial (Caco-2) cells: the effect of molecular weight, degree of deacetylation and exposure time. In: Peter, M.G., Domard, A., Muzzarelli, R.A.A. (Eds.), Advances in Chitin Science, vol. 4. Universität Potsdam, Schmergow, Germany, pp. 259-265.
    • (2000) Advances in Chitin Science , vol.4 , pp. 259-265
    • Holme, H.K.1    Hagen, A.2    Dornish, M.3
  • 17
    • 33646940975 scopus 로고    scopus 로고
    • Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability
    • DOI 10.1021/bc060077y
    • Hong, S., Leroueil, P.R., Janus, E.K., Peters, J.L., Kober, M.M., Islam, M.T., Orr, B.G., Baker Jr., J.R., Banaszak Holl, M.M., 2006. Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjug. Chem. 17, 728-734. (Pubitemid 43794383)
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.3 , pp. 728-734
    • Hong, S.1    Leroueil, P.R.2    Janus, E.K.3    Peters, J.L.4    Kober, M.-M.5    Islam, M.T.6    Orr, B.G.7    Baker Jr., J.R.8    Banaszak, H.M.M.9
  • 18
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and Cytotoxicity of Chitosan Molecules and Nanoparticles: Effects of Molecular Weight and Degree of Deacetylation
    • DOI 10.1023/B:PHAM.0000016249.52831.a5
    • Huang, M., Khor, E., Lim, L.Y., 2004. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm. Res. 21, 344-353. (Pubitemid 38221982)
    • (2004) Pharmaceutical Research , vol.21 , Issue.2 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.-Y.3
  • 19
    • 33750464057 scopus 로고    scopus 로고
    • High performance liquid chromatography for the determination of glucosamine sulfate in human plasma after derivatization with 9-fluorenylmethyl chloroformate
    • DOI 10.1002/jssc.200600162
    • Huang, T., Deng, C.H., Chen, N., Liu, Z., Duan, G.L., 2006. High performance liquid chromatography for the determination of glucosamine sulfate in human plasma after derivatization with 9-fluorenylmethyl chloroformate. J. Sep. Sci. 29, 2296-2302. (Pubitemid 44649643)
    • (2006) Journal of Separation Science , vol.29 , Issue.15 , pp. 2296-2302
    • Huang, T.-M.1    Deng, C.-H.2    Chen, N.-Z.3    Liu, Z.4    Duan, G.-L.5
  • 21
    • 0000350538 scopus 로고
    • Effects of chitosan hydrolyzates on lipid absorption and on serum and liver lipid concentration in rats
    • Ikeda, I., Sugano, M., Yoshida, K., Sasaki, E., Iwamoto, Y., Hatano, K., 1993. Effects of chitosan hydrolyzates on lipid absorption and on serum and liver lipid concentration in rats. J. Agric. Food Chem. 41, 431-435.
    • (1993) J. Agric. Food Chem. , vol.41 , pp. 431-435
    • Ikeda, I.1    Sugano, M.2    Yoshida, K.3    Sasaki, E.4    Iwamoto, Y.5    Hatano, K.6
  • 22
    • 0028124642 scopus 로고
    • Chitosan as a novel nasal delivery system for peptide drugs
    • DOI 10.1023/A:1018901302450
    • Illum, L., Farraj, N.F., Davis, S.S., 1994. Chitosan as a novel nasal delivery system for peptide drugs. Pharm. Res. 11, 1186-1189. (Pubitemid 24259861)
    • (1994) Pharmaceutical Research , vol.11 , Issue.8 , pp. 1186-1189
    • Illum, L.1    Farraj, N.F.2    Davis, S.S.3
  • 24
    • 44849099675 scopus 로고    scopus 로고
    • Enhancement of paclitaxel transport and cytotoxicity by 7,3′,4′-trimethoxyflavone, a P-glycoprotein inhibitor
    • Jeong, J.M., Choi, C.H., 2007. Enhancement of paclitaxel transport and cytotoxicity by 7,3′,4′-trimethoxyflavone, a P-glycoprotein inhibitor. J. Pharm. Pharm. Sci. 10, 547-553.
    • (2007) J. Pharm. Pharm. Sci. , vol.10 , pp. 547-553
    • Jeong, J.M.1    Choi, C.H.2
  • 25
    • 81255130871 scopus 로고    scopus 로고
    • Excipients as absorption enhancers
    • Krishna, R., Yu, L. (Eds.), Springer, New York, USA, (Chapter 6)
    • Junginger, H.E., 2007. Excipients as absorption enhancers. In: Krishna, R., Yu, L. (Eds.), Biopharmaceutics Applications in Drug Development. Springer, New York, USA, pp. 139-174 (Chapter 6).
    • (2007) Biopharmaceutics Applications in Drug Development , pp. 139-174
    • Junginger, H.E.1
  • 26
    • 16344377289 scopus 로고    scopus 로고
    • Trimethylated chitosans as non-viral gene delivery vectors: Cytotoxicity and transfection efficiency
    • DOI 10.1016/j.jconrel.2005.01.001
    • Kean, T., Roth, S., Thanou, M., 2005. Trimethylated chitosans as non-viral gene delivery vectors: cytotoxicity and transfection efficiency. J. Control. Release 103, 643-653. (Pubitemid 40471022)
    • (2005) Journal of Controlled Release , vol.103 , Issue.3 , pp. 643-653
    • Kean, T.1    Roth, S.2    Thanou, M.3
  • 27
    • 75149147526 scopus 로고    scopus 로고
    • Biodegradation, biodistribution and toxicity of chitosan
    • Kean, T., Thanou, M., 2010. Biodegradation, biodistribution and toxicity of chitosan. Adv. Drug Deliv. Rev. 62, 3-11.
    • (2010) Adv. Drug Deliv. Rev. , vol.62 , pp. 3-11
    • Kean, T.1    Thanou, M.2
  • 28
    • 0025373728 scopus 로고
    • Glucose transport and glucose transporters in muscle and their metabolic regulation
    • Klip, A., Paquet, M.R., 1990. Glucose transport and glucose transporters in muscle and their metabolic regulation. Diabetes Care 13, 228-243. (Pubitemid 20092110)
    • (1990) Diabetes Care , vol.13 , Issue.3 , pp. 228-243
    • Klip, A.1    Paquet, M.R.2
  • 31
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
    • Lehr, C.M., Bouwstra, J.A., Schacht, E.H., Junginger, H.E., 1992. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int. J. Pharm. 78, 43-48.
    • (1992) Int. J. Pharm. , vol.78 , pp. 43-48
    • Lehr, C.M.1    Bouwstra, J.A.2    Schacht, E.H.3    Junginger, H.E.4
  • 32
    • 33845493309 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolic drug interactions
    • Leucuta, S.E., Vlase, L., 2006. Pharmacokinetics and metabolic drug interactions. Curr. Clin. Pharmacol. 1, 5-20.
    • (2006) Curr. Clin. Pharmacol. , vol.1 , pp. 5-20
    • Leucuta, S.E.1    Vlase, L.2
  • 33
    • 84857637435 scopus 로고    scopus 로고
    • Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae
    • Li, C.R., Zhang, L., Zhou, L.M., Wo, S.K., Lin, G., Zuo, Z., 2012. Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. AAPS J. 14, 23-34.
    • (2012) AAPS J. , vol.14 , pp. 23-34
    • Li, C.R.1    Zhang, L.2    Zhou, L.M.3    Wo, S.K.4    Lin, G.5    Zuo, Z.6
  • 34
    • 33744798189 scopus 로고    scopus 로고
    • Osteoarthritis: Cellular and molecular changes in degenerating cartilage
    • DOI 10.1016/j.proghi.2006.02.003, PII S0079633606000052
    • Lorenz, H., Richter, W., 2006. Osteoarthritis: cellular and molecular changes in degenerating cartilage. Prog. Histochem. Cytochem. 40, 135-163. (Pubitemid 43833326)
    • (2006) Progress in Histochemistry and Cytochemistry , vol.40 , Issue.3 , pp. 135-163
    • Lorenz, H.1    Richter, W.2
  • 35
    • 0030453145 scopus 로고    scopus 로고
    • Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo
    • DOI 10.1023/A:1016488623022
    • Luessen, H.L., de Leeuw, B.J., Langemeyer, M.W., de Boer, A.B., Verhoef, J.C., Junginger, H.E., 1996. Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo. Pharm. Res. 13, 1668-1672. (Pubitemid 26426890)
    • (1996) Pharmaceutical Research , vol.13 , Issue.11 , pp. 1668-1672
    • Luessen, H.L.1    De Leeuw, B.J.2    Langemeyer, M.W.E.3    De Boer, A.G.4    Verhoef, J.C.5    Junginger, H.E.6
  • 36
    • 0346218085 scopus 로고    scopus 로고
    • Glucosamine: A Review of its Use in the Management of Osteoarthritis
    • DOI 10.2165/00002512-200320140-00004
    • Matheson, A.J., Perry, C.M., 2003. Glucosamine: a review of its use in the management of osteoarthritis. Drugs Aging 20, 1041-1060. (Pubitemid 37549879)
    • (2003) Drugs and Aging , vol.20 , Issue.14 , pp. 1041-1060
    • Matheson, A.J.1    Perry, C.M.2
  • 37
    • 0021252501 scopus 로고
    • Duodenal pH in health and duodenal ulcer disease: Effect of a meal, Coca-Cola, smoking, and cimetidine
    • McCloy, R.F., Greenberg, G.R., Baron, J.H., 1984. Duodenal pH in health and duodenal ulcer disease: effect of a meal, Coca-Cola, smoking, and cimetidine. Gut 25, 386-392. (Pubitemid 14136459)
    • (1984) Gut , vol.25 , Issue.4 , pp. 386-392
    • McCloy, R.F.1    Greenberg, G.R.2    Baron, J.H.3
  • 38
    • 49149092608 scopus 로고    scopus 로고
    • Comparison of pharmacokinetics of glucosamine and synovial fluid levels following administration of glucosamine sulphate or glucosamine hydrochloride
    • Meulyzer, M., Vachon, P., Beaudry, F., Vinardell, T., Richard, H., Beauchamp, G., Laverty, S., 2008. Comparison of pharmacokinetics of glucosamine and synovial fluid levels following administration of glucosamine sulphate or glucosamine hydrochloride. Osteoarthr. Cartil. 16, 973-979.
    • (2008) Osteoarthr. Cartil. , vol.16 , pp. 973-979
    • Meulyzer, M.1    Vachon, P.2    Beaudry, F.3    Vinardell, T.4    Richard, H.5    Beauchamp, G.6    Laverty, S.7
  • 39
    • 0024355622 scopus 로고
    • Biochemical characterisation of polycation-induced cytotoxicity to human vascular endothelial cells
    • Morgan, D.M., Larvin, V.L., Pearson, J.D., 1989. Biochemical characterisation of polycation-induced cytotoxicity to human vascular endothelial cells. J. Cell Sci. 94, 553-559. (Pubitemid 20002853)
    • (1989) Journal of Cell Science , vol.94 , Issue.3 , pp. 553-559
    • Morgan, D.M.L.1    Larvin, V.L.2    Pearson, J.D.3
  • 40
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63. (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 41
    • 84856187847 scopus 로고    scopus 로고
    • The extracellular matrix
    • Murray, R.K., Kennelly, P.J., Rodwell, V.W., Botham, K.M., Bender, D.A., Weil, P.A. (Eds.), McGraw-Hill, New York, (Chapter 48)
    • Murray, R.K., Keeley, F.W., 2009. The extracellular matrix. In: Murray, R.K., Kennelly, P.J., Rodwell, V.W., Botham, K.M., Bender, D.A., Weil, P.A. (Eds.), Harper's Illustrated Biochemistry. McGraw-Hill, New York, pp. 527-544 (Chapter 48).
    • (2009) Harper's Illustrated Biochemistry , pp. 527-544
    • Murray, R.K.1    Keeley, F.W.2
  • 42
    • 0043127396 scopus 로고    scopus 로고
    • ph-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: Implications for drug-drug interactions
    • DOI 10.1023/A:1025032511040
    • Neuhoff, S., Ungell, A.L., Zamora, I., Artursson, P., 2003. pH-dependent bidirectional transport of weakly basic drugs across Caco-2 monolayers: implications for drug-drug interactions. Pharm. Res. 20, 1141-1148. (Pubitemid 36951837)
    • (2003) Pharmaceutical Research , vol.20 , Issue.8 , pp. 1141-1148
    • Neuhoff, S.1    Ungell, A.-L.2    Zamora, I.3    Artursson, P.4
  • 43
    • 19444382806 scopus 로고    scopus 로고
    • pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers
    • DOI 10.1016/j.ejps.2005.02.009, PII S0928098705000692
    • Neuhoff, S., Ungell, A.L., Zamora, I., Artursson, P., 2005. pH-Dependent passive and active transport of acidic drugs across Caco-2 cell monolayers. Eur. J. Pharm. Sci. 25, 211-220. (Pubitemid 40725050)
    • (2005) European Journal of Pharmaceutical Sciences , vol.25 , Issue.2-3 , pp. 211-220
    • Neuhoff, S.1    Ungell, A.-L.2    Zamora, I.3    Artursson, P.4
  • 44
    • 27444432360 scopus 로고    scopus 로고
    • Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model
    • Ng, S.P., Wong, K.Y., Zhang, L., Zuo, Z., Lin, G., 2005. Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model. J. Pharm. Pharm. Sci. 8, 1-9. (Pubitemid 41528864)
    • (2005) Journal of Pharmacy and Pharmaceutical Sciences , vol.8 , Issue.1 , pp. 1-9
    • Ng, S.P.1    Wong, K.Y.2    Zhang, L.3    Zuo, Z.4    Lin, G.5
  • 46
    • 27944440047 scopus 로고    scopus 로고
    • Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man
    • DOI 10.1016/j.joca.2005.07.009, PII S1063458405001937
    • Persiani, S., Roda, E., Rovati, L.C., Locatelli, M., Giacovelli, G., Roda, A., 2005. Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man. Osteoarthr. Cartil. 13, 1041-1049. (Pubitemid 41672501)
    • (2005) Osteoarthritis and Cartilage , vol.13 , Issue.12 , pp. 1041-1049
    • Persiani, S.1    Roda, E.2    Rovati, L.C.3    Locatelli, M.4    Giacovelli, G.5    Roda, A.6
  • 47
    • 0034069558 scopus 로고    scopus 로고
    • Characterization of chitosan hydrochloride-mucin interaction by means of viscosimetric and turbidimetric measurements
    • DOI 10.1016/S0928-0987(00)00065-8, PII S0928098700000658
    • Rossi, S., Ferrari, F., Bonferoni, M.C., Caramella, C., 2000. Characterization of chitosan hydrochloride-mucin interaction by means of viscosimetric and turbidimetric measurements. Eur. J. Pharm. Sci. 10, 251-257. (Pubitemid 30317460)
    • (2000) European Journal of Pharmaceutical Sciences , vol.10 , Issue.4 , pp. 251-257
    • Rossi, S.1    Ferrari, F.2    Bonferoni, M.C.3    Caramella, C.4
  • 48
    • 84868647956 scopus 로고    scopus 로고
    • Crystalline glucosamine sulfate in the management of knee osteoarthritis: Efficacy, safety, and pharmacokinetic properties
    • Rovati, L.C., Girolami, F., Persiani, S., 2012. Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties. Ther. Adv. Musculoskelet. Dis. 4, 167-180.
    • (2012) Ther. Adv. Musculoskelet. Dis. , vol.4 , pp. 167-180
    • Rovati, L.C.1    Girolami, F.2    Persiani, S.3
  • 49
    • 0036843215 scopus 로고    scopus 로고
    • Active ingredient consistency of commercially available glucosamine sulfate products
    • Russell, A.S., Aghazadeh-Habashi, A., Jamali, F., 2002. Active ingredient consistency of commercially available glucosamine sulfate products. J. Rheumatol. 29, 2407-2409. (Pubitemid 35266035)
    • (2002) Journal of Rheumatology , vol.29 , Issue.11 , pp. 2407-2409
    • Russell, A.S.1    Aghazadeh-Habashi, A.2    Jamali, F.3
  • 50
    • 0030787377 scopus 로고    scopus 로고
    • Chitosans as absorption enhancers for poorly absorbable drugs 2: Mechanism of absorption enhancement
    • DOI 10.1023/A:1012160102740
    • Schipper, N.G.M., Olsson, S., Hoogstraate, J.A., deBoer, A.G., Varum, K.M., Artursson, P., 1997. Chitosans as absorption enhancers for poorly absorbable drugs. 2: mechanism of absorption enhancement. Pharm. Res. 14, 923-929. (Pubitemid 27326989)
    • (1997) Pharmaceutical Research , vol.14 , Issue.7 , pp. 923-929
    • Schipper, N.G.M.1    Olsson, S.2    Hoogstraate, J.A.3    DeBoer, A.G.4    Varum, K.M.5    Artursson, P.6
  • 51
    • 0030455292 scopus 로고    scopus 로고
    • Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells
    • DOI 10.1023/A:1016444808000
    • Schipper, N.G.M., Varum, K.M., Artursson, P., 1996. Chitosans as absorption enhancers for poorly absorbable drugs. 1: influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells. Pharm. Res. 13, 1686-1692. (Pubitemid 26426893)
    • (1996) Pharmaceutical Research , vol.13 , Issue.11 , pp. 1686-1692
    • Schipper, N.G.M.1    Varum, K.M.2    Artursson, P.3
  • 52
    • 0345643513 scopus 로고    scopus 로고
    • Chitosans as absorption enhancers of poorly absorbable drugs. 3: Influence of mucus on absorption enhancement
    • DOI 10.1016/S0928-0987(99)00032-9, PII S0928098799000329
    • Schipper, N.G.M., Varum, K.M., Stenberg, P., Ocklind, G., Lennernas, H., Artursson, P., 1999. Chitosans as absorption enhancers of poorly absorbable drugs. 3: influence of mucus on absorption enhancement. Eur. J. Pharm. Sci. 8, 335-343. (Pubitemid 29325026)
    • (1999) European Journal of Pharmaceutical Sciences , vol.8 , Issue.4 , pp. 335-343
    • Schipper, N.G.M.1    Varum, K.M.2    Stenberg, P.3    Ocklind, G.4    Lennernas, H.5    Artursson, P.6
  • 54
    • 0037433789 scopus 로고    scopus 로고
    • Enhancing effect of chitosan on nasal absorption of salmon calcitonin in rats: Comparison with hydroxypropyl- and dimethyl-beta-cyclodextrins
    • DOI 10.1016/S0378-5173(03)00090-5
    • Sinswat, P., Tengamnuay, P., 2003. Enhancing effect of chitosan on nasal absorption of salmon calcitonin in rats: comparison with hydroxypropyl- and dimethylbeta-cyclodextrins. Int. J. Pharm. 257, 15-22. (Pubitemid 36507028)
    • (2003) International Journal of Pharmaceutics , vol.257 , Issue.1-2 , pp. 15-22
    • Sinswat, P.1    Tengamnuay, P.2
  • 55
    • 1642579659 scopus 로고    scopus 로고
    • Effect of Chitosan on Epithelial Cell Tight Junctions
    • DOI 10.1023/B:PHAM.0000012150.60180.e3
    • Smith, J., Wood, E., Dornish, M., 2004. Effect of chitosan on epithelial cell tight junctions. Pharm. Res. 21, 43-49. (Pubitemid 38122290)
    • (2004) Pharmaceutical Research , vol.21 , Issue.1 , pp. 43-49
    • Smith, J.1    Wood, E.2    Dornish, M.3
  • 57
    • 0029895328 scopus 로고    scopus 로고
    • Enteral absorption of insulin in rats from mucoadhesive Chitosan-Coated liposomes
    • DOI 10.1023/A:1016009313548
    • Takeuchi, H., Yamamoto, H., Niwa, T., Hino, T., Kawashima, Y., 1996. Enteral absorption of insulin in rats from mucoadhesive chitosan-coated liposomes. Pharm. Res. 13, 896-901. (Pubitemid 26227747)
    • (1996) Pharmaceutical Research , vol.13 , Issue.6 , pp. 896-901
    • Takeuchi, H.1    Yamamoto, H.2    Niwa, T.3    Hino, T.4    Kawashima, Y.5
  • 58
    • 0035813752 scopus 로고    scopus 로고
    • Oral drug absorption enhancement by chitosan and its derivatives
    • DOI 10.1016/S0169-409X(01)00231-9, PII S0169409X01002319
    • Thanou, M., Verhoef, J.C., Junginger, H.E., 2001. Oral drug absorption enhancement by chitosan and its derivatives. Adv. Drug Deliv. Rev. 52, 117-126. (Pubitemid 33079167)
    • (2001) Advanced Drug Delivery Reviews , vol.52 , Issue.2 , pp. 117-126
    • Thanou, M.1    Verhoef, J.C.2    Junginger, H.E.3
  • 59
    • 35948940759 scopus 로고    scopus 로고
    • Glucosamine therapy for osteoarthritis: An update
    • Towheed, T.E., Anastassiades, T., 2007. Glucosamine therapy for osteoarthritis: an update. J. Rheumatol. 34, 1787-1790. (Pubitemid 350067633)
    • (2007) Journal of Rheumatology , vol.34 , Issue.9 , pp. 1787-1790
    • Towheed, T.E.1    Anastassiades, T.2
  • 62
    • 0033456147 scopus 로고    scopus 로고
    • Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: Their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-D-maltopyranoside
    • Uchiyama, T., Sugiyama, T., Quan, Y.S., Kotani, A., Okada, N., Fujita, T., Muranishi, S., Yamamoto, A., 1999. Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-D- maltopyranoside. J. Pharm. Pharmacol. 51, 1241-1250. (Pubitemid 30006463)
    • (1999) Journal of Pharmacy and Pharmacology , vol.51 , Issue.11 , pp. 1241-1250
    • Uchiyama, T.1    Sugiyama, T.2    Quan, Y.-S.3    Kotani, A.4    Okada, N.5    Fujita, T.6    Muranishi, S.7    Yamamoto, A.8
  • 63
    • 0037205745 scopus 로고    scopus 로고
    • GLUT2 is a high affinity glucosamine transporter
    • DOI 10.1016/S0014-5793(02)03058-2, PII S0014579302030582
    • Uldry, M., Ibberson, M., Hosokawa, M., Thorens, B., 2002. GLUT2 is a high affinity glucosamine transporter. FEBS Lett. 524, 199-203. (Pubitemid 34804860)
    • (2002) FEBS Letters , vol.524 , Issue.1-3 , pp. 199-203
    • Uldry, M.1    Ibberson, M.2    Hosokawa, M.3    Thorens, B.4
  • 65
    • 29944433234 scopus 로고    scopus 로고
    • Effect of the co-occurring components from green tea on the intestinal absorption and disposition of green tea polyphenols in Caco-2 monolayer model
    • DOI 10.1211/jpp.58.1.0005
    • Zhang, L., Chow, M.S., Zuo, Z., 2006. Effect of the co-occurring components from green tea on the intestinal absorption and disposition of green tea polyphenols in Caco-2 monolayer model. J. Pharm. Pharmacol. 58, 37-44. (Pubitemid 43041994)
    • (2006) Journal of Pharmacy and Pharmacology , vol.58 , Issue.1 , pp. 37-44
    • Zhang, L.1    Chow, M.S.S.2    Zuo, Z.3
  • 66
    • 34249297623 scopus 로고    scopus 로고
    • Mechanistic study on the intestinal absorption and disposition of baicalein
    • DOI 10.1016/j.ejps.2007.04.001, PII S0928098707000814
    • Zhang, L., Lin, G., Kovacs, B., Jani, M., Krajcsi, P., Zuo, Z., 2007. Mechanistic study on the intestinal absorption and disposition of baicalein. Eur. J. Pharm. Sci. 31, 221-231. (Pubitemid 46818982)
    • (2007) European Journal of Pharmaceutical Sciences , vol.31 , Issue.3-4 , pp. 221-231
    • Zhang, L.1    Lin, G.2    Kovacs, B.3    Jani, M.4    Krajcsi, P.5    Zuo, Z.6
  • 67
    • 84870453271 scopus 로고    scopus 로고
    • Improvement of intestinal absorption of forsythoside A in weeping forsythia extract by various absorption enhancers based on tight junctions
    • Zhou, W., Qin, K.M., Shan, J.J., Ju, W.Z., Liu, S.J., Cai, B.C., Di, L.Q., 2012. Improvement of intestinal absorption of forsythoside A in weeping forsythia extract by various absorption enhancers based on tight junctions. Phytomedicine 20, 47-58.
    • (2012) Phytomedicine , vol.20 , pp. 47-58
    • Zhou, W.1    Qin, K.M.2    Shan, J.J.3    Ju, W.Z.4    Liu, S.J.5    Cai, B.C.6    Di, L.Q.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.