Effect of the co-occurring components from green tea on the intestinal absorption and disposition of green tea polyphenols in Caco-2 monolayer model

Journal of Pharmacy and Pharmacology

Volumn 58, Issue 1, 2006, Pages 37-44

  Zhang, Li ^a   Chow, Moses S S ^a   Zuo, Zhong ^a  

^a Prince of Wales Hospital   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; EPICATECHIN; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; EPIGALLOCATECHIN SULFATE; GREEN TEA EXTRACT; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; DRUG METABOLISM; DRUG PENETRATION; DRUG TRANSPORT; ELECTROCHEMICAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; MASS SPECTROMETRY; TEA;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; CAMELLIA SINENSIS; CATECHIN; HUMANS; INTESTINAL ABSORPTION; PLANT EXTRACTS; PLANT LEAVES; TEA;

EID: 29944433234     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.58.1.0005     Document Type: Article

References (24)

1. Artursson, P., Karlsson, J. (1991) Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem. Biophys. Res. Commun. 175: 880-885
2. Cantelli-Forti, G., Raggi, M. A., Bugamelli, F., Maffei, F., Villari, A., Trieff, N. M. (1997) Toxicological assessment of liquorice: biliary excretion in rats. Pharmacol. Res. 35: 463-410
3. Chang, Q., Zuo, Z., Ho, W. K. K., Chow, M. S. S. (2005) Comparison of the pharmacokinetics of hawthorn phenolics in extract versus individual pure compound. J. Clin. Pharmacol. 45: 106-112
4. Chen, L., Lee, M. J., Li, H., Yang, C. S. (1997) Absorption, distribution, elimination of tea polyphenols in rats. Drug Metab. Dispos. 25: 1045-1050
5. Chen, Z., Zhu, Q. Y., Wong, Y. F., Zhang, Z., Cheng, H. Y. (1998) Stabilizing effect of ascorbic acid on green tea catechins. J. Agric. Food. Chem. 46: 2512-2516
6. Chow, H. S., Cai, Y., Alberts, D. S., Hakim, I., Dorr, R., Shahi, F., Crowell, J. A., Yang, C. S., Hara, Y. (2001) Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenol E. Cancer Epidemiol. Biomarker Prev. 10: 53-58
7. Duffy, S. J., Vita, J. A., Holbrook, M., Swerdloff, P. L., Keaney, J. F. (2001) Effect of acute and chronic tea consumption on platelet aggregation in patients with coronary artery disease. Arterioscler. Thromb. Vasc. 21: 1084-1089
8. Hong, J., Lambert, J. D., Lee, S. H., Sinko, P. J., Yang, C. S. (2003) Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. Biochem. Biophys. Res. Commun. 310: 222-227
9. Jia, X., Chen, J., Lin, H., Hu, M. (2004) Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates. J. Pharmacol. Exp. Ther. 310: 1103-1113
10. Katiyar, S. K., Mukhtar, H. (1996) Tea in chemoprevention of cancer: epidemiologic and experimental studies. Int. J. Oncol. 8: 221-238
11. Keung, W. M., Lazo, O., Kunze, L., Vallee, B. L. (1996) Potentiation of the bioavailability of daidzin by an extract of Radix puerariae. Proc. Natl Acad. Sci. 93: 4284-4288
12. Kuhnle, G., Spencer, J. P., Schroeter, H., Shenoy, B., Debnam, E. S., Srai, S. K., Rice-Evans, C. Hahn, U. (2000) Epicatechin and catechin are O-methylated and glucuronidated in the small intestine. Biochem. Biophys. Res. Commun. 277: 507-512
13. Lu, H., Meng, X. F., Yang, C. S. (2003) Enzymology of methylation of tea catechins and inhibition of catechol-O-methyltransferase by (-)-epigallocatechin gallate. Drug Metab. Dispos. 31: 572-579
14. Meaney, C. M., O'Driscoll C. M. (2000) A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt: fatty acid micellar systems using the Caco-2 cell culture model. Int. J. Pharm. 207: 21-30
15. Meng, X., Lee, M. J., Li, C., Sheng, S., Zhu, N., Sang, S., Ho, C. T., Yang, C. S. (2001) Formation and identification of 4′-O-methyl-(-)- epigallocatechin in humans. Drug Metab. Dispos. 29: 789-793
16. Takehiko, Y., Mujo, K. (1997) Chemistry and applications of green tea. New York, CRC Press, Chapter 1
17. Vaidyanathan, J. B., Walle, T. (2001) Transport and metabolism of the tea flavonoid (-)-epicatechin by the human intestinal cell line Caco-2. Pharm. Res. 18: 1420-1425
18. Vaidyanathan, J. B., Walle, T. (2002) Glucuronidation and sulfation of the tea flavonoid (-)-epicatechin by the human and rat enzymes. Drug Metab. Dispos. 30: 897-903
19. Vaidyanathan, J. B., Walle, T. (2003) Cellular uptake and efflux of the tea flavonoid (-)-epicatechin-3-gallate in the human intestinal cell line Caco-2. J. Pharm. Exp. Ther. 307: 745-752
20. Wang, Z., Nishioka, M., Kurosaki, Y., Nakayama, T., Kimura T. (1995) Gastrointestinal absorption characteristics of glycyrrhizin from glycyrrhiza extract. Biol. Pharm. Bull. 18: 1238-1241
21. Warden, B. A., Smith, L. S., Beecher, G. R., Balentine, D. A., Clevidence, B. A. (2001) Catechins are bioavailable in men and women drinking black tea throughout the day. J. Nutr. 131: 1731-1737
22. Young, J. F., Dragsted, L. O., Haraldsdottir, J., Daneshvar, B., Kail, M. A., Loft, S., Nilsson, L., Nielsen, S. E., Mayer, B., Skibsted, L. H., Huynh-Ba, T., Hermetter, A., Sandstrom, B. (2002) Green tea extract only affects markers of oxidative status postprandially: lasting antioxidant effect of flavonoid-free diet. Br. J. Nutr. 87: 343-355
23. Zhang, L., Zheng, Y., Chow, M. S. S., Zuo, Z. (2004) Investigation of intestinal absorption and disposition of green tea catechins by Caco-2 monolayer model. Int. J. Pharm. 287: 1-12
24. Zhu, M., Chen, Y., Li, R. C. (2000) Oral absorption and bioavailability of tea catechins. Planta Med. 66: 444-447