Mechanism of Porcine Liver Xanthine Oxidoreductase Mediated N-Oxide Reduction of Cyadox as Revealed by Docking and Mutagenesis Studies

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Chen, Chigang ^a   Cheng, Guyue ^a   Hao, Haihong ^a   Dai, Menghong ^a   Wang, Xu ^a   Huang, Lingli ^a   Liu, Zhenli ^a   Yuan, Zonghui ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; CIADOX; COMPLEMENTARY DNA; GLYCINE; LYSINE; SERINE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; LIVER; MALE; METABOLISM; MOLECULAR DOCKING; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING SITES; CLONING, MOLECULAR; ENZYME ACTIVATION; GENE EXPRESSION; KINETICS; LIVER; MALE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION; QUINOXALINES; RECOMBINANT PROTEINS; SWINE; XANTHINE DEHYDROGENASE;

EID: 84883628770     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073912     Document Type: Article

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