SCOPUS 정보 검색 플랫폼

Journal of Computer-Aided Molecular Design

Volumn 24, Issue 1, 2010, Pages 57-75

A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors

(4) Ali, Hamed I a Fujita, Takayuki a Akaho, Eiichi b Nagamatsu, Tomohisa a

a OKAYAMA UNIVERSITY (Japan)

b KOBE GAKUIN UNIVERSITY (Japan)

Author keywords

AutoDock; CAChe; PMF; Pyrazolopyrimidine; Structure activity relationship; Xanthine oxidase inhibitor

Indexed keywords

AROMATIC COMPOUNDS; BINDING ENERGY; COMPLEXATION; ENZYMES; LIGANDS;

ACTIVE SITE; AUTODOCK; CACHE; COMPARATIVES STUDIES; PMF; PYRAZOLOPYRIMIDINE; SCORING PERFORMANCE; STRUCTURE-ACTIVITY RELATIONSHIPS; XANTHINE OXIDASE; XANTHINE OXIDASE INHIBITOR;

HYDROGEN BONDS;

2 NAPHTHOL; 4 ALKYLIDENEHYDRAZINO 1H PYRAZOLOL[3,4 D]PYRIMIDINE DERIVATIVE; 4 ARYLMETHYLIDENEHYDRAZINO 1H PYRAZOLOL[3,4 D]PYRIMIDINE DERIVATIVE; ALLOPURINOL; FEBUXOSTAT; FYX 051; LIGAND; MOLYBDOPTERIN; OXIPURINOL; PYRAZOLOPYRIMIDINE DERIVATIVE; PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVE; SALICYLIC ACID; UNCLASSIFIED DRUG; URIC ACID; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE; XANTHINE OXIDASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROGEN BOND; IC 50; MOLECULAR DOCKING; MOLECULAR INTERACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCORING SYSTEM; STRUCTURE ACTIVITY RELATION;

EID: 76449121008 PISSN: 0920654X EISSN: 15734951 Source Type: Journal
DOI: 10.1007/s10822-009-9314-z Document Type: Article

Times cited : (45)

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