Mammalian xanthine oxidoreductase - Mechanism of transition from xanthine dehydrogenase to xanthine oxidase

FEBS Journal

Volumn 275, Issue 13, 2008, Pages 3278-3289

  Nishino, Tomoko ^a   Okamoto, Ken ^a   Eger, Bryan T ^b   Pai, Emil F ^b   Nishino, Takeshi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

cation interaction; Flavin semiquinone; Hydrogen peroxide; Iron sulfur center; Molybdopterin cofactor; Reactive oxygen species; Superoxide; Xanthine dehydrogenase; Xanthine oxidase; Xanthine oxidoreductase

Indexed keywords

CYSTEINE; HYDROGEN PEROXIDE; MOLYBDENUM; SUPEROXIDE; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROXYLATION; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; SITE DIRECTED MUTAGENESIS; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CYSTEINE; DISULFIDES; HUMANS; MITOCHONDRIA; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; SEQUENCE HOMOLOGY, AMINO ACID; THERMODYNAMICS; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

MAMMALIA;

EID: 44949262935     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06489.x     Document Type: Review

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