메뉴 건너뛰기




Volumn 67-68, Issue , 2012, Pages 175-185

In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry

Author keywords

Cyadox; In vitro; Metabolism; UPLC Q TOF MS

Indexed keywords

CIADOX; DRUG METABOLITE;

EID: 84862142558     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.04.004     Document Type: Article
Times cited : (33)

References (31)
  • 1
    • 0025375354 scopus 로고
    • Clinical signs and performance of pigs treated with different doses of carbadox, cyadox and olaquindox
    • Nabuurs M.J., Van Der Molen E.J., De Graaf G.J., Jager L.P. Clinical signs and performance of pigs treated with different doses of carbadox, cyadox and olaquindox. Zentralbl. Veterinarmed. A 1990, 37:68-76.
    • (1990) Zentralbl. Veterinarmed. A , vol.37 , pp. 68-76
    • Nabuurs, M.J.1    Van Der Molen, E.J.2    De Graaf, G.J.3    Jager, L.P.4
  • 2
    • 0024694305 scopus 로고
    • Comparative study of the effect of the carbadox, olaquindox and cyadox on aldosterone, sodium and potassium plasma levels in weaned pigs
    • Van Der Molen E.J., Baars A.J., De Graaf G.J., Jager L.P. Comparative study of the effect of the carbadox, olaquindox and cyadox on aldosterone, sodium and potassium plasma levels in weaned pigs. Res. Vet. Sci. 1989, 47:11-16.
    • (1989) Res. Vet. Sci. , vol.47 , pp. 11-16
    • Van Der Molen, E.J.1    Baars, A.J.2    De Graaf, G.J.3    Jager, L.P.4
  • 3
    • 28844458799 scopus 로고    scopus 로고
    • Subchronic oral toxicity study with cyadox in Wistar rats
    • Fang G.J., He Q.H., Zhou S.Q., Yuan Z.H., et al. Subchronic oral toxicity study with cyadox in Wistar rats. Food Chem. Toxicol. 2006, 44:36-41.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 36-41
    • Fang, G.J.1    He, Q.H.2    Zhou, S.Q.3    Yuan, Z.H.4
  • 4
    • 77952314460 scopus 로고    scopus 로고
    • ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro
    • Huang X.J., Zhang H.H., Wang X., Yuan Z.H., et al. ROS mediated cytotoxicity of porcine adrenocortical cells induced by QdNOs derivatives in vitro. Chem-Biol Interact. 2010, 185:227-234.
    • (2010) Chem-Biol Interact. , vol.185 , pp. 227-234
    • Huang, X.J.1    Zhang, H.H.2    Wang, X.3    Yuan, Z.H.4
  • 7
    • 0020530983 scopus 로고
    • Cytogenetic effects of quinoxaline-1,4-dioxide-type growth promoting agents II, metaphase analysis in mice
    • Clihak R., Vonotorkova M. Cytogenetic effects of quinoxaline-1,4-dioxide-type growth promoting agents II, metaphase analysis in mice. Mutat. Res. 1983, 117:311-316.
    • (1983) Mutat. Res. , vol.117 , pp. 311-316
    • Clihak, R.1    Vonotorkova, M.2
  • 8
    • 2042535787 scopus 로고
    • Determination of cyadox and its metabolites in plasma by adsorptive voltammetry
    • Sestakova I., Kopanica M. Determination of cyadox and its metabolites in plasma by adsorptive voltammetry. Talanta 1988, 35:816-818.
    • (1988) Talanta , vol.35 , pp. 816-818
    • Sestakova, I.1    Kopanica, M.2
  • 9
    • 53249089990 scopus 로고    scopus 로고
    • Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken
    • Huang L.L., Wang Y.L., Yuan Z.H., et al. Development of high performance liquid chromatographic methods for the determination of cyadox and its metabolites in plasma and tissues of chicken. J. Chromatogr. B 2008, 874:7-14.
    • (2008) J. Chromatogr. B , vol.874 , pp. 7-14
    • Huang, L.L.1    Wang, Y.L.2    Yuan, Z.H.3
  • 10
    • 67650360063 scopus 로고    scopus 로고
    • Metabolism of cyadox in rat, chicken and pig liver microsomes and identification of metabolites by accurate mass measurements using electrospray ionization hybrid ion trap/time-of flight mass spectrometry
    • Liu Z.Y., Huang L.L., Dai M.H., Yuan Z.H., et al. Metabolism of cyadox in rat, chicken and pig liver microsomes and identification of metabolites by accurate mass measurements using electrospray ionization hybrid ion trap/time-of flight mass spectrometry. Rapid Commun. Mass Spectrom. 2009, 23:2026-2034.
    • (2009) Rapid Commun. Mass Spectrom. , vol.23 , pp. 2026-2034
    • Liu, Z.Y.1    Huang, L.L.2    Dai, M.H.3    Yuan, Z.H.4
  • 11
    • 80053296914 scopus 로고    scopus 로고
    • Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry
    • Xu N., Huang L.L., Yuan Z.H., et al. Metabolism of cyadox by the intestinal mucosa microsomes and gut flora of swine, and identification of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 2011, 25:2333-2344.
    • (2011) Rapid Commun. Mass Spectrom. , vol.25 , pp. 2333-2344
    • Xu, N.1    Huang, L.L.2    Yuan, Z.H.3
  • 12
    • 0030428226 scopus 로고    scopus 로고
    • In vitro techniques for studying drug metabolism
    • Guengerich F.P. In vitro techniques for studying drug metabolism. J. Pharmacokinet. Biopharm. 1996, 24:521-533.
    • (1996) J. Pharmacokinet. Biopharm. , vol.24 , pp. 521-533
    • Guengerich, F.P.1
  • 13
    • 50849084986 scopus 로고    scopus 로고
    • The gastrointestinal microbiota as a site for the biotransformation of drugs
    • Sousaa T., Patersonb R., Moore V., et al. The gastrointestinal microbiota as a site for the biotransformation of drugs. Int. J. Pharm. 2008, 363:1-25.
    • (2008) Int. J. Pharm. , vol.363 , pp. 1-25
    • Sousaa, T.1    Patersonb, R.2    Moore, V.3
  • 14
    • 0026349867 scopus 로고
    • Isolation of P450 enzymes from human liver
    • Raucy J.L., Lasker J.M. Isolation of P450 enzymes from human liver. Methods Enzymol. 1991, 206:577-587.
    • (1991) Methods Enzymol. , vol.206 , pp. 577-587
    • Raucy, J.L.1    Lasker, J.M.2
  • 15
    • 0026763295 scopus 로고
    • Effects of various medium formulations and attachment substrata on the performance of cultured ruminant hepatocytes in biotransformation studies
    • Van't Klooster G.A., Woutersen-Van Nijnanten F.M., Klein W.R., Blaauboer B.J., et al. Effects of various medium formulations and attachment substrata on the performance of cultured ruminant hepatocytes in biotransformation studies. Xenobiotica 1992, 22:523-534.
    • (1992) Xenobiotica , vol.22 , pp. 523-534
    • Van't Klooster, G.A.1    Woutersen-Van Nijnanten, F.M.2    Klein, W.R.3    Blaauboer, B.J.4
  • 16
    • 0029810170 scopus 로고    scopus 로고
    • The use of cultured hepatocytes from goats and cattle to investigate xenobiotic oxidative metabolism
    • Montesissa C., Anfossi P., Van't Klooster G., Mengelers M. The use of cultured hepatocytes from goats and cattle to investigate xenobiotic oxidative metabolism. Vet. Res. Commun. 1996, 20:449-460.
    • (1996) Vet. Res. Commun. , vol.20 , pp. 449-460
    • Montesissa, C.1    Anfossi, P.2    Van't Klooster, G.3    Mengelers, M.4
  • 17
    • 0027722209 scopus 로고
    • Sulphadimidine metabolism in vitro: comparative studies in cultured rat, goat, sheep and cattle hepatocytes
    • Van't Klooster G.A., Blaauboer B.J., Noordhoek J., van Miert A.S. Sulphadimidine metabolism in vitro: comparative studies in cultured rat, goat, sheep and cattle hepatocytes. J. Vet. Pharmacol. Ther. 1993, 16:454-461.
    • (1993) J. Vet. Pharmacol. Ther. , vol.16 , pp. 454-461
    • Van't Klooster, G.A.1    Blaauboer, B.J.2    Noordhoek, J.3    van Miert, A.S.4
  • 18
    • 0015757745 scopus 로고
    • Metabolism of foreign compounds by gastrointestinal microorganisms
    • Scheline R.R. Metabolism of foreign compounds by gastrointestinal microorganisms. Pharmacol. Rev. 1973, 25:451-523.
    • (1973) Pharmacol. Rev. , vol.25 , pp. 451-523
    • Scheline, R.R.1
  • 19
    • 0023680667 scopus 로고
    • Interaction of the gut microflora and the host in toxicology
    • Rowland I.R. Interaction of the gut microflora and the host in toxicology. Toxicol. Pathol. 1988, 16:147-153.
    • (1988) Toxicol. Pathol. , vol.16 , pp. 147-153
    • Rowland, I.R.1
  • 20
    • 58849124556 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry in in vitro drug metabolite screening
    • Tolonen A., Turpeinen M., Pelkonen O. Liquid chromatography-mass spectrometry in in vitro drug metabolite screening. Drug Discovery Today 2009, 14:120-133.
    • (2009) Drug Discovery Today , vol.14 , pp. 120-133
    • Tolonen, A.1    Turpeinen, M.2    Pelkonen, O.3
  • 21
    • 48749115768 scopus 로고    scopus 로고
    • Mass spectrometry for the identification of the discriminating signals from metabolomics: current status and future trends
    • Werner E., Heilier J.F., Tabet J.C., et al. Mass spectrometry for the identification of the discriminating signals from metabolomics: current status and future trends. J. Chromatogr. B 2008, 871:143-163.
    • (2008) J. Chromatogr. B , vol.871 , pp. 143-163
    • Werner, E.1    Heilier, J.F.2    Tabet, J.C.3
  • 22
    • 30344473926 scopus 로고    scopus 로고
    • Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for atropine and its eleven metabolites in Rat urine
    • Chen H.X., Chen Y., Zhang H.S., et al. Sensitive and specific liquid chromatographic-tandem mass spectrometric assay for atropine and its eleven metabolites in Rat urine. J. Pharm. Biomed. Anal. 2006, 40:142-150.
    • (2006) J. Pharm. Biomed. Anal. , vol.40 , pp. 142-150
    • Chen, H.X.1    Chen, Y.2    Zhang, H.S.3
  • 24
    • 33748902567 scopus 로고    scopus 로고
    • Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data
    • Zhu M., Ma L., Zhang D., Ray K., et al. Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data. Drug Metab. Dispos. 2006, 34:1722-1733.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 1722-1733
    • Zhu, M.1    Ma, L.2    Zhang, D.3    Ray, K.4
  • 25
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura T., Sato R. The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 1964, 239:2370-2378.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 26
    • 0029680696 scopus 로고    scopus 로고
    • A comparative study of precision cut liver slices, hepatocytes and liver microsomes from the Wistar rat using metronidazole as a model substance
    • Sidelmann U.G., Cornett C., Tjornelund J., et al. A comparative study of precision cut liver slices, hepatocytes and liver microsomes from the Wistar rat using metronidazole as a model substance. Xenobiotica 1996, 26:709-722.
    • (1996) Xenobiotica , vol.26 , pp. 709-722
    • Sidelmann, U.G.1    Cornett, C.2    Tjornelund, J.3
  • 27
    • 80054921927 scopus 로고    scopus 로고
    • Preparation of human liver microsomes and determination of cytochrome P450
    • Tang Y.N., Zhang S.G., Li L., et al. Preparation of human liver microsomes and determination of cytochrome P450. China J. Hosp. Pharm. 1998, 12:535-537.
    • (1998) China J. Hosp. Pharm. , vol.12 , pp. 535-537
    • Tang, Y.N.1    Zhang, S.G.2    Li, L.3
  • 29
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol. 1975, 13:29-83.
    • (1975) Methods Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 30
    • 0033046389 scopus 로고    scopus 로고
    • Induction of cytochrome-P450 in cryopreserved rat and human hepatoctyes
    • Silva J.M., Day S.H., Nicoll-Griffith D.A. Induction of cytochrome-P450 in cryopreserved rat and human hepatoctyes. Chem. Biol. Interact. 1999, 121:49-63.
    • (1999) Chem. Biol. Interact. , vol.121 , pp. 49-63
    • Silva, J.M.1    Day, S.H.2    Nicoll-Griffith, D.A.3
  • 31
    • 0001694820 scopus 로고
    • Isolated hepatocytes preparation, properties and applications
    • Elsevier, Amsterdam, R.H. Burdon, P.H. van Knippenberg (Eds.)
    • Berry M.N., Edwards A.M., Barrit C.J. Isolated hepatocytes preparation, properties and applications. Laboratory Techniques in Biochemistry and Molecular Biology 1991, 83-98. Elsevier, Amsterdam. R.H. Burdon, P.H. van Knippenberg (Eds.).
    • (1991) Laboratory Techniques in Biochemistry and Molecular Biology , pp. 83-98
    • Berry, M.N.1    Edwards, A.M.2    Barrit, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.