-
1
-
-
76149084859
-
Role of A-type lamins in signaling, transcription, and chromatin organization
-
doi: 10.1083/jcb.200904124 Pubmed Abstract
-
Andres, V., and Gonzalez, J. M. (2009). Role of A-type lamins in signaling, transcription, and chromatin organization. J. Cell Biol. 187, 945-957. doi: 10.1083/jcb.200904124 Pubmed Abstract
-
(2009)
J. Cell Biol.
, vol.187
, pp. 945-957
-
-
Andres, V.1
Gonzalez, J.M.2
-
2
-
-
77955385716
-
Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
-
doi: 10.1242/jcs.067306
-
Benson, E. K., Lee, S. W., and Aaronson, S. A. (2010). Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence. J. Cell Sci. 123, 2605-2612. doi: 10.1242/jcs.067306
-
(2010)
J. Cell Sci.
, vol.123
, pp. 2605-2612
-
-
Benson, E.K.1
Lee, S.W.2
Aaronson, S.A.3
-
3
-
-
0035929353
-
Switching and signaling at the telomere
-
doi: 10.1016/S0092-8674(01)00492-5
-
Blackburn, E. H. (2001). Switching and signaling at the telomere. Cell 106, 661-673. doi: 10.1016/S0092-8674(01)00492-5
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
4
-
-
33745915850
-
Nuclear lamins: laminopathies and their role in premature ageing
-
doi: 10.1152/physrev.00047.2005
-
Broers, J. L., Ramaekers, F. C., Bonne, G., Yaou, R. B., and Hutchison, C. J. (2006). Nuclear lamins: laminopathies and their role in premature ageing. Physiol. Rev. 86, 967-1008. doi: 10.1152/physrev.00047.2005
-
(2006)
Physiol. Rev.
, vol.86
, pp. 967-1008
-
-
Broers, J.L.1
Ramaekers, F.C.2
Bonne, G.3
Yaou, R.B.4
Hutchison, C.J.5
-
5
-
-
0042736696
-
LMNA mutations in atypical Werner's syndrome
-
doi: 10.1016/S0140-6736(03)14069-X
-
Chen, L., Lee, L., Kudlow, B. A., Dos Santos, H. G., Sletvold, O., Shafeghati, Y., et al. (2003). LMNA mutations in atypical Werner's syndrome. Lancet 362, 440-445. doi: 10.1016/S0140-6736(03)14069-X
-
(2003)
Lancet
, vol.362
, pp. 440-445
-
-
Chen, L.1
Lee, L.2
Kudlow, B.A.3
Dos Santos, H.G.4
Sletvold, O.5
Shafeghati, Y.6
-
6
-
-
84865263603
-
The human CST complex is a terminator of telomerase activity
-
doi: 10.1038/nature11269
-
Chen, L. Y., Redon, S., and Lingner, J. (2012). The human CST complex is a terminator of telomerase activity. Nature 488, 540-544. doi: 10.1038/nature11269
-
(2012)
Nature
, vol.488
, pp. 540-544
-
-
Chen, L.Y.1
Redon, S.2
Lingner, J.3
-
7
-
-
10344256183
-
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
-
doi: 10.1126/science.1103619
-
Crabbe, L., Verdun, R. E., Haggblom, C. I., and Karlseder, J. (2004). Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306, 1951-1953. doi: 10.1126/science.1103619
-
(2004)
Science
, vol.306
, pp. 1951-1953
-
-
Crabbe, L.1
Verdun, R.E.2
Haggblom, C.I.3
Karlseder, J.4
-
8
-
-
33745904741
-
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome
-
doi: 10.1073/pnas.0601058103
-
Dahl, K. N., Scaffidi, P., Islam, M. F., Yodh, A. G., Wilson, K. L., and Misteli, T. (2006). Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc. Natl. Acad. Sci. U.S.A. 103, 10271-10276. doi: 10.1073/pnas.0601058103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 10271-10276
-
-
Dahl, K.N.1
Scaffidi, P.2
Islam, M.F.3
Yodh, A.G.4
Wilson, K.L.5
Misteli, T.6
-
9
-
-
12344305602
-
LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly
-
doi: 10.1242/jcs.01529
-
Dechat, T., Gajewski, A., Korbei, B., Gerlich, D., Daigle, N., Haraguchi, T., et al. (2004). LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly. J. Cell Sci. 117, 6117-6128. doi: 10.1242/jcs.01529
-
(2004)
J. Cell Sci.
, vol.117
, pp. 6117-6128
-
-
Dechat, T.1
Gajewski, A.2
Korbei, B.3
Gerlich, D.4
Daigle, N.5
Haraguchi, T.6
-
10
-
-
41649097238
-
Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
-
doi: 10.1101/gad.1652708
-
Dechat, T., Pfleghaar, K., Sengupta, K., Shimi, T., Shumaker, D. K., Solimando, L., et al. (2008). Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev. 22, 832-853. doi: 10.1101/gad.1652708
-
(2008)
Genes Dev.
, vol.22
, pp. 832-853
-
-
Dechat, T.1
Pfleghaar, K.2
Sengupta, K.3
Shimi, T.4
Shumaker, D.K.5
Solimando, L.6
-
11
-
-
24944460598
-
Shelterin: the protein complex that shapes and safeguards human telomeres
-
doi: 10.1101/gad.1346005
-
de Lange, T. (2005). Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 19, 2100-2110. doi: 10.1101/gad.1346005
-
(2005)
Genes Dev.
, vol.19
, pp. 2100-2110
-
-
de Lange, T.1
-
12
-
-
34548317418
-
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
-
doi: 10.1038/nature06065
-
Denchi, E. L., and de Lange, T. (2007). Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 448, 1068-1071. doi: 10.1038/nature06065
-
(2007)
Nature
, vol.448
, pp. 1068-1071
-
-
Denchi, E.L.1
de Lange, T.2
-
13
-
-
10744229294
-
Lamin a truncation in Hutchinson-Gilford progeria
-
doi: 10.1126/science.1084125
-
De Sandre-Giovannoli, A., Bernard, R., Cau, P., Navarro, C., Amiel, J., Boccaccio, I., et al. (2003). Lamin a truncation in Hutchinson-Gilford progeria. Science 300, 2055. doi: 10.1126/science.1084125
-
(2003)
Science
, vol.300
, pp. 2055
-
-
De Sandre-Giovannoli, A.1
Bernard, R.2
Cau, P.3
Navarro, C.4
Amiel, J.5
Boccaccio, I.6
-
14
-
-
0037673950
-
Recurrent de novo point mutations in lamin a cause Hutchinson-Gilford progeria syndrome
-
doi: 10.1038/nature01629
-
Eriksson, M., Brown, W. T., Gordon, L. B., Glynn, M. W., Singer, J., Scott, L., et al. (2003). Recurrent de novo point mutations in lamin a cause Hutchinson-Gilford progeria syndrome. Nature 423, 293-298. doi: 10.1038/nature01629
-
(2003)
Nature
, vol.423
, pp. 293-298
-
-
Eriksson, M.1
Brown, W.T.2
Gordon, L.B.3
Glynn, M.W.4
Singer, J.5
Scott, L.6
-
15
-
-
77954025436
-
WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations
-
doi: 10.1007/s00439-010-0832-5
-
Friedrich, K., Lee, L., Leistritz, D. F., Nurnberg, G., Saha, B., Hisama, F. M., et al. (2010). WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations. Hum. Genet. 128, 103-111. doi: 10.1007/s00439-010-0832-5
-
(2010)
Hum. Genet.
, vol.128
, pp. 103-111
-
-
Friedrich, K.1
Lee, L.2
Leistritz, D.F.3
Nurnberg, G.4
Saha, B.5
Hisama, F.M.6
-
16
-
-
78649819167
-
Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence
-
doi: 10.1038/ncb2123
-
Fujita, K., Horikawa, I., Mondal, A. M., Jenkins, L. M., Appella, E., Vojtesek, B., et al. (2010). Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Nat. Cell Biol. 12, 1205-1212. doi: 10.1038/ncb2123
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1205-1212
-
-
Fujita, K.1
Horikawa, I.2
Mondal, A.M.3
Jenkins, L.M.4
Appella, E.5
Vojtesek, B.6
-
17
-
-
77957663987
-
Nurturing the genome: A-type lamins preserve genomic stability
-
doi: 10.4161/nucl.1.2.10797
-
Gonzalez-Suarez, I., and Gonzalo, S. (2010). Nurturing the genome: A-type lamins preserve genomic stability. Nucleus 1, 129-135. doi: 10.4161/nucl.1.2.10797
-
(2010)
Nucleus
, vol.1
, pp. 129-135
-
-
Gonzalez-Suarez, I.1
Gonzalo, S.2
-
18
-
-
69249222566
-
Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
-
doi: 10.1038/emboj.2009.196
-
Gonzalez-Suarez, I., Redwood, A. B., Perkins, S. M., Vermolen, B., Lichtensztejin, D., Grotsky, D. A., et al. (2009). Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J. 28, 2414-2427. doi: 10.1038/emboj.2009.196
-
(2009)
EMBO J.
, vol.28
, pp. 2414-2427
-
-
Gonzalez-Suarez, I.1
Redwood, A.B.2
Perkins, S.M.3
Vermolen, B.4
Lichtensztejin, D.5
Grotsky, D.A.6
-
19
-
-
76349123622
-
Sequencing newly replicated DNA reveals widespread plasticity in human replication timing
-
doi: 10.1073/pnas.0912402107
-
Hansen, R. S., Thomas, S., Sandstrom, R., Canfield, T. K., Thurman, R. E., Weaver, M., et al. (2010). Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc. Natl. Acad. Sci. U.S.A. 107, 139-144. doi: 10.1073/pnas.0912402107
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 139-144
-
-
Hansen, R.S.1
Thomas, S.2
Sandstrom, R.3
Canfield, T.K.4
Thurman, R.E.5
Weaver, M.6
-
20
-
-
84872286638
-
mTORC1 and p53: clash of the gods?
-
doi: 10.4161/cc.22912
-
Hasty, P., Sharp, Z. D., Curiel, T. J., and Campisi, J. (2013). mTORC1 and p53: clash of the gods? Cell Cycle 12, 20-25. doi: 10.4161/cc.22912
-
(2013)
Cell Cycle
, vol.12
, pp. 20-25
-
-
Hasty, P.1
Sharp, Z.D.2
Curiel, T.J.3
Campisi, J.4
-
21
-
-
81955161812
-
Coronary artery disease in a Werner syndrome-like form of progeria characterized by low levels of progerin, a splice variant of lamin A
-
doi: 10.1002/ajmg.a.34336
-
Hisama, F. M., Lessel, D., Leistritz, D., Friedrich, K., McBride, K. L., Pastore, M. T., et al. (2011). Coronary artery disease in a Werner syndrome-like form of progeria characterized by low levels of progerin, a splice variant of lamin A. Am. J. Med. Genet. A 155A, 3002-3006. doi: 10.1002/ajmg.a.34336
-
(2011)
Am. J. Med. Genet. A
, vol.155 A
, pp. 3002-3006
-
-
Hisama, F.M.1
Lessel, D.2
Leistritz, D.3
Friedrich, K.4
McBride, K.L.5
Pastore, M.T.6
-
22
-
-
36549024516
-
Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A
-
doi: 10.1016/j.yexcr.2007.08.004
-
Huang, S., Risques, R. A., Martin, G. M., Rabinovitch, P. S., and Oshima, J. (2008). Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A. Exp. Cell Res. 314, 82-91. doi: 10.1016/j.yexcr.2007.08.004
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 82-91
-
-
Huang, S.1
Risques, R.A.2
Martin, G.M.3
Rabinovitch, P.S.4
Oshima, J.5
-
23
-
-
59449095581
-
Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53
-
doi: 10.1091/mbc. E08-05-0492
-
Kudlow, B. A., Stanfel, M. N., Burtner, C. R., Johnston, E. D., and Kennedy, B. K. (2008). Suppression of proliferative defects associated with processing-defective lamin A mutants by hTERT or inactivation of p53. Mol. Biol. Cell 19, 5238-5248. doi: 10.1091/mbc. E08-05-0492
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5238-5248
-
-
Kudlow, B.A.1
Stanfel, M.N.2
Burtner, C.R.3
Johnston, E.D.4
Kennedy, B.K.5
-
24
-
-
22544466685
-
Genomic instability in laminopathy-based premature aging
-
doi: 10.1038/nm1266
-
Liu, B., Wang, J., Chan, K. M., Tjia, W. M., Deng, W., Guan, X., et al. (2005). Genomic instability in laminopathy-based premature aging. Nat. Med. 11, 780-785. doi: 10.1038/nm1266
-
(2005)
Nat. Med.
, vol.11
, pp. 780-785
-
-
Liu, B.1
Wang, J.2
Chan, K.M.3
Tjia, W.M.4
Deng, W.5
Guan, X.6
-
25
-
-
33845699084
-
DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A
-
doi: 10.1242/jcs.03263
-
Liu, Y., Rusinol, A., Sinensky, M., Wang, Y., and Zou, Y. (2006). DNA damage responses in progeroid syndromes arise from defective maturation of prelamin A. J. Cell Sci. 119, 4644-4649. doi: 10.1242/jcs.03263
-
(2006)
J. Cell Sci.
, vol.119
, pp. 4644-4649
-
-
Liu, Y.1
Rusinol, A.2
Sinensky, M.3
Wang, Y.4
Zou, Y.5
-
26
-
-
0029827128
-
Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex
-
doi: 10.1083/jcb.135.4.867
-
Luderus, M. E., van Steensel, B., Chong, L., Sibon, O. C., Cremers, F. F., and de Lange, T. (1996). Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J. Cell Biol. 135, 867-881. doi: 10.1083/jcb.135.4.867
-
(1996)
J. Cell Biol.
, vol.135
, pp. 867-881
-
-
Luderus, M.E.1
van Steensel, B.2
Chong, L.3
Sibon, O.C.4
Cremers, F.F.5
de Lange, T.6
-
27
-
-
34548737554
-
TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination
-
doi: 10.1073/pnas.0702410104
-
Mao, Z., Seluanov, A., Jiang, Y., and Gorbunova, V. (2007). TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. Proc. Natl. Acad. Sci. U.S.A. 104, 13068-13073. doi: 10.1073/pnas.0702410104
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 13068-13073
-
-
Mao, Z.1
Seluanov, A.2
Jiang, Y.3
Gorbunova, V.4
-
28
-
-
46249086799
-
Premature aging in mice activates a systemic metabolic response involving autophagy induction
-
doi: 10.1093/hmg/ddn120
-
Marino, G., Ugalde, A. P., Salvador-Montoliu, N., Varela, I., Quiros, P. M., Cadinanos, J., et al. (2008). Premature aging in mice activates a systemic metabolic response involving autophagy induction. Hum. Mol. Genet. 17, 2196-2211. doi: 10.1093/hmg/ddn120
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 2196-2211
-
-
Marino, G.1
Ugalde, A.P.2
Salvador-Montoliu, N.3
Varela, I.4
Quiros, P.M.5
Cadinanos, J.6
-
29
-
-
0017840139
-
Genetic syndromes in man with potential relevance to the pathobiology of aging
-
Martin, G. M. (1978). Genetic syndromes in man with potential relevance to the pathobiology of aging. Birth Defects Orig. Artic. Ser. 14, 5-39.
-
(1978)
Birth Defects Orig. Artic. Ser.
, vol.14
, pp. 5-39
-
-
Martin, G.M.1
-
30
-
-
81855198154
-
DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome
-
doi: 10.1042/BST20110687
-
Musich, P. R., and Zou, Y. (2011). DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome. Biochem. Soc. Trans. 39, 1764-1769. doi: 10.1042/BST20110687
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1764-1769
-
-
Musich, P.R.1
Zou, Y.2
-
31
-
-
18844396775
-
Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells
-
doi: 10.1038/sj.onc.1208482
-
Nijjar, T., Bassett, E., Garbe, J., Takenaka, Y., Stampfer, M. R., Gilley, D., et al. (2005). Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells. Oncogene 24, 3369-3376. doi: 10.1038/sj.onc.1208482
-
(2005)
Oncogene
, vol.24
, pp. 3369-3376
-
-
Nijjar, T.1
Bassett, E.2
Garbe, J.3
Takenaka, Y.4
Stampfer, M.R.5
Gilley, D.6
-
32
-
-
0037509953
-
Telomere attrition and Chk2 activation in human heart failure
-
doi: 10.1073/pnas.0836098100
-
Oh, H., Wang, S. C., Prahash, A., Sano, M., Moravec, C. S., Taffet, G. E., et al. (2003). Telomere attrition and Chk2 activation in human heart failure. Proc. Natl. Acad. Sci. U.S.A. 100, 5378-5383. doi: 10.1073/pnas.0836098100
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 5378-5383
-
-
Oh, H.1
Wang, S.C.2
Prahash, A.3
Sano, M.4
Moravec, C.S.5
Taffet, G.E.6
-
33
-
-
84874351566
-
A two-step mechanism for TRF2-mediated chromosome-end protection
-
doi: 10.1038/nature11873
-
Okamoto, K., Bartocci, C., Ouzounov, I., Diedrich, J. K., Yates, J. R. III, and Denchi, E. L. (2013). A two-step mechanism for TRF2-mediated chromosome-end protection. Nature 494, 502-505. doi: 10.1038/nature11873
-
(2013)
Nature
, vol.494
, pp. 502-505
-
-
Okamoto, K.1
Bartocci, C.2
Ouzounov, I.3
Diedrich, J.K.4
Yates, J.R.5
Denchi, E.L.6
-
34
-
-
0028898823
-
Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors
-
doi: 10.1002/jcp.1041620213
-
Oshima, J., Campisi, J., Tannock, T. C., and Martin, G. M. (1995). Regulation of c-fos expression in senescing Werner syndrome fibroblasts differs from that observed in senescing fibroblasts from normal donors. J. Cell. Physiol. 162, 277-283. doi: 10.1002/jcp.1041620213
-
(1995)
J. Cell. Physiol.
, vol.162
, pp. 277-283
-
-
Oshima, J.1
Campisi, J.2
Tannock, T.C.3
Martin, G.M.4
-
35
-
-
1942438108
-
Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms
-
doi: 10.1002/cyto.a.20006
-
O'Sullivan, J. N., Finley, J. C., Risques, R. A., Shen, W. T., Gollahon, K. A., Moskovitz, A. H., et al. (2004). Telomere length assessment in tissue sections by quantitative FISH: image analysis algorithms. Cytometry A 58, 120-131. doi: 10.1002/cyto.a.20006
-
(2004)
Cytometry A
, vol.58
, pp. 120-131
-
-
O'Sullivan, J.N.1
Finley, J.C.2
Risques, R.A.3
Shen, W.T.4
Gollahon, K.A.5
Moskovitz, A.H.6
-
36
-
-
46249125488
-
How shelterin protects mammalian telomeres
-
doi: 10.1146/annurev.genet.41.110306.130350
-
Palm, W., and de Lange, T. (2008). How shelterin protects mammalian telomeres. Annu. Rev. Genet. 42, 301-334. doi: 10.1146/annurev.genet.41.110306.130350
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 301-334
-
-
Palm, W.1
de Lange, T.2
-
37
-
-
0037047298
-
Reversible manipulation of telomerase expression and telomere length
-
doi: 10.1074/jbc. M203747200
-
Rubio, M. A., Kim, S. H., and Campisi, J. (2002). Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells. J. Biol. Chem. 277, 28609-28617. doi: 10.1074/jbc. M203747200
-
(2002)
Implications for the ionizing radiation response and replicative senescence of human cells. J. Biol. Chem.
, vol.277
, pp. 28609-28617
-
-
Rubio, M.A.1
Kim, S.H.2
Campisi, J.3
-
38
-
-
79952164245
-
A novel LMNA mutation causes altered nuclear morphology and symptoms of familial partial lipodystrophy (Dunnigan variety) with progeroid features
-
doi: 10.1159/000320166
-
Saha, B., Lessel, D., Hisama, F. M., Leistritz, D. F., Friedrich, K., Martin, G. M., et al. (2010). A novel LMNA mutation causes altered nuclear morphology and symptoms of familial partial lipodystrophy (Dunnigan variety) with progeroid features. Mol. Syndromol. 1, 127-132. doi: 10.1159/000320166
-
(2010)
Mol. Syndromol.
, vol.1
, pp. 127-132
-
-
Saha, B.1
Lessel, D.2
Hisama, F.M.3
Leistritz, D.F.4
Friedrich, K.5
Martin, G.M.6
-
39
-
-
33646745137
-
Lamin A-dependent nuclear defects in human aging
-
doi: 10.1126/science.1127168
-
Scaffidi, P., and Misteli, T. (2006). Lamin A-dependent nuclear defects in human aging. Science 312, 1059-1063. doi: 10.1126/science.1127168
-
(2006)
Science
, vol.312
, pp. 1059-1063
-
-
Scaffidi, P.1
Misteli, T.2
-
40
-
-
43149124203
-
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing
-
doi: 10.1038/ncb1708
-
Scaffidi, P., and Misteli, T. (2008). Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat. Cell Biol. 10, 452-459. doi: 10.1038/ncb1708
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 452-459
-
-
Scaffidi, P.1
Misteli, T.2
-
41
-
-
84860456242
-
Removal of shelterin reveals the telomere end-protection problem
-
doi: 10.1126/science.1218498
-
Sfeir, A., and de Lange, T. (2012). Removal of shelterin reveals the telomere end-protection problem. Science 336, 593-597. doi: 10.1126/science.1218498
-
(2012)
Science
, vol.336
, pp. 593-597
-
-
Sfeir, A.1
de Lange, T.2
-
42
-
-
33745016642
-
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
-
doi: 10.1073/pnas.0602569103
-
Shumaker, D. K., Dechat, T., Kohlmaier, A., Adam, S. A., Bozovsky, M. R., Erdos, M. R., et al. (2006). Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc. Natl. Acad. Sci. U.S.A. 103, 8703-8708. doi: 10.1073/pnas.0602569103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 8703-8708
-
-
Shumaker, D.K.1
Dechat, T.2
Kohlmaier, A.3
Adam, S.A.4
Bozovsky, M.R.5
Erdos, M.R.6
-
43
-
-
84863842252
-
Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
-
doi: 10.1038/emboj.2012.132
-
Suram, A., Kaplunov, J., Patel, P. L., Ruan, H., Cerutti, A., Boccardi, V., et al. (2012). Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 31, 2839-2851. doi: 10.1038/emboj.2012.132
-
(2012)
EMBO J.
, vol.31
, pp. 2839-2851
-
-
Suram, A.1
Kaplunov, J.2
Patel, P.L.3
Ruan, H.4
Cerutti, A.5
Boccardi, V.6
-
44
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
doi: 10.1126/science.272.5259.258
-
Yu, C. E., Oshima, J., Fu, Y. H., Wijsman, E. M., Hisama, F., Alisch, R., et al. (1996). Positional cloning of the Werner's syndrome gene. Science 272, 258-262. doi: 10.1126/science.272.5259.258
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
-
45
-
-
1842584782
-
Proteins that bind A-type lamins: integrating isolated clues
-
doi: 10.1242/jcs.01102
-
Zastrow, M. S., Vlcek, S., and Wilson, K. L. (2004). Proteins that bind A-type lamins: integrating isolated clues. J. Cell Sci. 117, 979-987. doi: 10.1242/jcs.01102
-
(2004)
J. Cell Sci.
, vol.117
, pp. 979-987
-
-
Zastrow, M.S.1
Vlcek, S.2
Wilson, K.L.3
-
46
-
-
73149108422
-
G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells
-
doi: 10.1158/1535-7163.MCT-09-0244
-
Zhou, W. J., Deng, R., Zhang, X. Y., Feng, G. K., Gu, L. Q., and Zhu, X. F. (2009). G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. Mol. Cancer Ther. 8, 3203-3213. doi: 10.1158/1535-7163.MCT-09-0244
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 3203-3213
-
-
Zhou, W.J.1
Deng, R.2
Zhang, X.Y.3
Feng, G.K.4
Gu, L.Q.5
Zhu, X.F.6
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