G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells

Molecular Cancer Therapeutics

Volumn 8, Issue 12, 2009, Pages 3203-3213

  Zhou, Wen Jun ^a   Deng, Rong ^a   Zhang, Xiao Yue ^a   Feng, Gong Kan ^a   Gu, Lian Quan ^b   Zhu, Xiao Feng ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ANTINEOPLASTIC AGENT; ATM PROTEIN; AUTOPHAGY PROTEIN 5; DNA; GENE PRODUCT; GUANINE QUADRUPLEX; HISTONE H2A; PROTEASOME; PROTEIN LC3; SMALL INTERFERING RNA; SYUIQ 5; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CARCINOMA CELL; CNE2 CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; FEMALE; FLUORESCENCE ANALYSIS; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IC 50; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TELOMERE;

AUTOPHAGY; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DIAMINES; DNA DAMAGE; DNA-BINDING PROTEINS; G-QUADRUPLEXES; HELA CELLS; HISTONES; HUMANS; IMMUNOBLOTTING; LIGANDS; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN-SERINE-THREONINE KINASES; QUINOLINES; RNA INTERFERENCE; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 2; TUMOR SUPPRESSOR PROTEINS;

EID: 73149108422     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0244     Document Type: Article

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