Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 3, 2013, Pages 453-462

  Hirota, Jeremy A ^a   Hiebert, Paul R ^a   Gold, Matt ^b   Wu, Dan ^a   Graydon, Colin ^a   Smith, Jane Ann ^c   Ask, Kjetil ^c   McNagny, Kelly ^b   Granville, David J ^a   Knight, Darryl A ^a  

^a The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; Apoptosis; Granzyme B

Indexed keywords

CYTOKINE; GRANZYME B;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; EFFECTOR CELL; ENZYME DEFICIENCY; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; LYMPHOCYTE; MOUSE; NONHUMAN; PNEUMONIA; REGULATORY T LYMPHOCYTE;

ACUTE LUNG INJURY; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIGENS, CD; BLEOMYCIN; CASE-CONTROL STUDIES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; GRANZYMES; HUMANS; KILLER CELLS, NATURAL; LUNG; MICE; MICE, KNOCKOUT; PNEUMONIA; RESPIRATORY DISTRESS SYNDROME, ADULT; SURVIVAL ANALYSIS; T-LYMPHOCYTES, REGULATORY;

EID: 84883474220     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0512OC     Document Type: Article

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