Pivotal role of CCR1-positive leukocytes in bleomycin-induced lung fibrosis in mice

Journal of Immunology

Volumn 164, Issue 5, 2000, Pages 2745-2751

  Tokuda, Atsuko ^a,b   Itakura, Meiji ^a,b   Onai, Nobuyuki ^a   Kimura, Hiroshi ^b   Kuriyama, Takayuki ^b   Matsushima, Kouji ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN SULFATE; CHEMOKINE RECEPTOR; COMPLEMENTARY DNA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; POLYCLONAL ANTIBODY; RANTES;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG INDUCED DISEASE; FEMALE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LUNG FIBROSIS; LUNG INJURY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0034161676     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.5.2745     Document Type: Article

References (31)

1. Smith, R. E., R. M. Strieter, K. Zhang, S. H. Phan, T. J. Standiford, N. W. Lukacs, and S. L. Kunkel. 1995. A role for C-C chemokines in fibrotic lung disease. J. Leukocyte Biol. 57:782.
2. Piguet, P. F., S. Kaufman, C. Barazzone, M. Muller, B. Ryffel, and H. P. Eugster. 1997. Resistance of TNF/LT α double deficient mice to bleomycin-induced fibrosis. Int. J. Exp. Pathol. 78:43.
3. Ortiz, L. A., J. Lasky, G. Lungarella, E. Cavarra, P. Martorana, W. A. Banks, J. J. Peschon, H. L. Schmidts, A. R. Brody, and M. Friedman. 1999. Upregulation of the p75 but not the p55 TNF-α receptor mRNA after silica and bleomycin exposure and protection from lung injury in double receptor knockout mice. Am. J. Respir. Cell Mol. Biol. 20:825.
4. Zhang, K., M. Gharaee-Kermani, B. McGarry, D. Remick, and S. H. Phan. 1997. TNF-α-mediated lung cytokine networking and eosinophil recruitment in pulmonary fibrosis. J. Immunol. 158:954.
5. Piguet, P. F., and C. Vesin. 1994. Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice. Eur. Respir. J. 7:515.
6. Giri, S. N., D. M. Hyde, and M. A. Hollinger. 1993. Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice. Thorax 48:959.
7. Munger, J. S., X. Huang, H. Kawakatsu, M. J. Griffiths, S. L. Dalton, J. Wu, J. F. Pittet, N. Kaminski, C. Garat, M. A. Matthay, et al. 1999. The integrin α v β 6 binds and activates latent TGFβ1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 96:319.
8. Smith, R. E., R. M. Strieter, S. H. Phan, N. W. Lukacs, G. B. Huffnagle, C. A. Wilke, M. D. Burdick, P. Lincoln, H. Evanoff, and S. L. Kunkel. 1994. Production and function of mutine macrophage inflammatory protein-1 α in bleomycin-induced lung injury J. Immunol. 153:4704.
9. Zhang, K., M. Gharaee-Kermani, M. L. Jones, J. S. Warren, and S. H. Phan. 1994. Lung monocyte chemoattractant protein-1 gene expression in bleomycin-induced pulmonary fibrosis. J. Immunol. 153:4733.
10. Keane, M. P., J. A. Belperio, T. A. Moore, B. B. Moore, D. A. Arenberg, R. E. Smith, M. D. Burdick, S. L. Kunkel, and R. M. Strieter. 1999. Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis. J. Immunol. 162:5511.
11. Standiford, T. J., M. W. Rolfe, S. L. Kunkel, J. P. D. Lynch, M. D. Burdick, A. R. Gilbert, M. B. Orringer, R. I. Whyte, and R. M. Strieter. 1993. Macrophage inflammatory protein-1 α expression in interstitial lung disease. J. Immunol. 151: 2852.
12. Kodama, N., E. Yamaguchi, N. Hizawa, K. Furuya, J. Kojima, M. Oguri, T. Takahashi, and Y. Kawakami. 1998. Expression of RANTES by bronchoalveolar lavage cells in nonsmoking patients with interstitial lung diseases. Am. J. Respir. Cell Mol. Biol. 18:526.
13. Boomars, K. A., R. C. Schweizer, P. Zanen, J. M. van den Bosch, J. W. Lammers, and L. Koenderman. 1998. Eosinophil chemotactic activity in bronchoalveolar lavage from idiopathic pulmonary fibrosis is dependent on cytokine priming of eosinophils. Eur. Respir. J. 11:1001.
14. Petrek, M., P. Pantelidis, A. M. Southcott, P. Lympany, P. Safranek, C. M. Black, V. Kolek, E. Weigl, and R. M. du Bois. 1997. The source and role of RANTES in interstitial lung disease. Eur. Respir. J. 10:1207.
15. Helene, M., V. Lake-Bullock, J. Zhu, H. Hao, D. A. Cohen, and A. M. Kaplan. 1999. T cell independence of bleomycin-induced pulmonary fibrosis. J. Leukocyte Biol. 65:187.
16. Schrier, D. J., S. H. Phan, and B. M. McGarry. 1983. The effects of the nude (nu/nu) mutation on bleomycin-induced pulmonary fibrosis: a biochemical evaluation. Am. Rev. Respir. Dis. 127:614.
17. Su, S. B., N. Mukaida, J. Wang, H. Nomura, and K. Matsushima. 1996. Preparation of specific polyclonal antibodies to a C-C chcmokine receptor. CCR1, and determination of CCR1 expression on various types of leukocytes. J. Leukocyte Biol. 60:658.
18. Neote, K., D. DiGregorio, J. Y. Mak, R. Horuk, and T. J. Schall. 1993. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 72:415.
19. Sallusto, F., and A. Lanzavecchia. 1999. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J. Exp. Med. 189:611.
20. Ogata, M., Y. Zhang, Y. Wang, M. Itakura, Y. Y. Zhang, A. Harada, S. Hashimoto, and K. Matsushima. 1999. Chemotactic response toward chemokines and its regulation by transforming growth factor-β1 of murine bone marrow hematopoietic progenitor cell-derived different subset of dendritic cells. Blood 93:3225.
21. Yoneyama, H., A. Harada, T. Imai, M. Baba, O. Yoshie, Y. Zhang, H. Higashi, M. Murai, H. Asakura, and K. Matsushima. 1998. Pivotal role of TARC, a CC chemokine, in bacteria-induced fulminant hepatic failure in mice. J. Clin. Invest. 102:1933.
22. 8+ T lymphocytes in the pathogenesis of liver injury in graft-versus-host disease. J. Clin. Invest. 104:49.
23. Baggiolini, M. 1998. Chemokines and leukocyte traffic. Nature 392:565.
24. Zhang, S., B. S. Youn, J. L. Gao, P. M. Murphy, and B. S. Kwon. 1999. Differential effects of leukotactin-1 and macrophage inflammatory protein-1α on neutrophils mediated by CCR1. J. Immunol. 162:4938.
25. Kuwano, K., N. Hagimoto, M. Kawasaki, T. Yatomi, N. Nakamura, S. Nagata, T. Suda, R. Kunitake, T. Maeyama, H. Miyazaki, and N. Hara. 1999. Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J. Clin. Invest. 104:13.
26. Baggiolini, M., and B. Moser. 1997. Blocking chemokine receptors. J. Exp. Med. 186: 1189.
27. Hesselgesser, J., H. P. Ng, M. Liang, W. Zheng, K. May, J. G. Bauman, S. Monahan, I. Islam, G. P. Wei, A. Ghannam, et al. 1998. Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor. J. Biol. Chem. 273:15687.
28. Gao, J. L., T. A. Wynn, Y. Chang, E. J. Lee, H. E. Broxmeyer, S. Cooper, H. L. Tiffany, H. Westphal, J. Kwon-Chung, and P. M. Murphy. 1997. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J. Exp. Med. 185:1959.
29. Kurihara, T., G. Warr, J. Loy, and R. Bravo. 1997. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor. J. Exp. Med. 186:1757.
30. Warmington, K. S., L. Boring, J. H. Ruth, J. Sonstein, C. M. Hogaboam, J. L. Curtis, S. L. Kunkel, I. R. Charo, and S. W. Chensue. 1999. Effect of C-C chemokine receptor 2 (CCR2) knockout on type-2 (schistosomal antigen-elicited) pulmonary granuloma formation: analysis of cellular recruitment and cytokine responses. Am. J. Pathol. 154:1407.
31. Gerard, C., J. L. Frossard, M. Bhatia, A. Saluja, N. P. Gerard, B. Lu, and M. Steer. 1997. Targeted disruption of the β-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. J. Clin. Invest. 100:2022.