메뉴 건너뛰기




Volumn 13, Issue 9, 2013, Pages 2245-2254

Osteoimmunology and its implications for transplantation

Author keywords

Bone; PTH

Indexed keywords

ESTROGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 7; OSTEOCLAST DIFFERENTIATION FACTOR; PARATHYROID HORMONE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; WNT10B PROTEIN;

EID: 84883462844     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12380     Document Type: Review
Times cited : (36)

References (86)
  • 2
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong YY, Feige U, Sarosi I, et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999; 402: 304-309.
    • (1999) Nature , vol.402 , pp. 304-309
    • Kong, Y.Y.1    Feige, U.2    Sarosi, I.3
  • 3
    • 0033805254 scopus 로고    scopus 로고
    • Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection
    • Teng YT, Nguyen H, Gao X, et al. Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection. J Clin Invest 2000; 106: 59-67.
    • (2000) J Clin Invest , vol.106 , pp. 59-67
    • Teng, Y.T.1    Nguyen, H.2    Gao, X.3
  • 4
    • 79960414809 scopus 로고    scopus 로고
    • CD8+ T cells regulate bone tumor burden independent of osteoclast resorption
    • Zhang K, Kim S, Cremasco V, et al. CD8+ T cells regulate bone tumor burden independent of osteoclast resorption. Cancer Res 2011; 71: 4799-4808.
    • (2011) Cancer Res , vol.71 , pp. 4799-4808
    • Zhang, K.1    Kim, S.2    Cremasco, V.3
  • 5
    • 84856148387 scopus 로고    scopus 로고
    • Role of T cells in ovariectomy induced bone loss-revisited
    • Pacifici R., Role of T cells in ovariectomy induced bone loss-revisited. J Bone Miner Res 2012; 27: 231-239.
    • (2012) J Bone Miner Res , vol.27 , pp. 231-239
    • Pacifici, R.1
  • 6
    • 34247323904 scopus 로고    scopus 로고
    • B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo
    • Li Y, Toraldo G, Li A, et al. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood 2007; 109: 3839-3848.
    • (2007) Blood , vol.109 , pp. 3839-3848
    • Li, Y.1    Toraldo, G.2    Li, A.3
  • 7
    • 79551676415 scopus 로고    scopus 로고
    • Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand
    • Li JY, Tawfeek H, Bedi B, et al. Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand. Proc Natl Acad Sci USA 2011; 108: 768-773.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 768-773
    • Li, J.Y.1    Tawfeek, H.2    Bedi, B.3
  • 8
    • 84869788379 scopus 로고    scopus 로고
    • PTH expands short-term murine hemopoietic stem cells through T cells
    • Li JY, Adams J, Calvi LM, et al. PTH expands short-term murine hemopoietic stem cells through T cells. Blood 2012; 120: 4352-4362.
    • (2012) Blood , vol.120 , pp. 4352-4362
    • Li, J.Y.1    Adams, J.2    Calvi, L.M.3
  • 10
    • 84861316694 scopus 로고    scopus 로고
    • The gut microbiota regulates bone mass in mice
    • Sjogren K, Engdahl C, Henning P, et al. The gut microbiota regulates bone mass in mice. J Bone Miner Res 2012; 27: 1357-1367.
    • (2012) J Bone Miner Res , vol.27 , pp. 1357-1367
    • Sjogren, K.1    Engdahl, C.2    Henning, P.3
  • 11
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato K, Suematsu A, Okamoto K, et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J Exp Med 2006; 203: 2673-2682.
    • (2006) J Exp Med , vol.203 , pp. 2673-2682
    • Sato, K.1    Suematsu, A.2    Okamoto, K.3
  • 12
    • 4043071317 scopus 로고    scopus 로고
    • Cutting edge: Estrogen drives expansion of the CD4+ CD25+ regulatory T cell compartment
    • Polanczyk MJ, Carson BD, Subramanian S, et al. Cutting edge: Estrogen drives expansion of the CD4+ CD25+ regulatory T cell compartment. J Immunol 2004; 173: 2227-2230.
    • (2004) J Immunol , vol.173 , pp. 2227-2230
    • Polanczyk, M.J.1    Carson, B.D.2    Subramanian, S.3
  • 13
    • 37149026641 scopus 로고    scopus 로고
    • Treg cells suppress osteoclast formation: A new link between the immune system and bone
    • Zaiss MM, Axmann R, Zwerina J, et al. Treg cells suppress osteoclast formation: A new link between the immune system and bone. Arthritis Rheum 2007; 56: 4104-4112.
    • (2007) Arthritis Rheum , vol.56 , pp. 4104-4112
    • Zaiss, M.M.1    Axmann, R.2    Zwerina, J.3
  • 14
    • 77953639101 scopus 로고    scopus 로고
    • Regulatory T cells protect from local and systemic bone destruction in arthritis
    • Zaiss MM, Frey B, Hess A, et al. Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol 2010; 184: 7238-7246.
    • (2010) J Immunol , vol.184 , pp. 7238-7246
    • Zaiss, M.M.1    Frey, B.2    Hess, A.3
  • 15
    • 77955373402 scopus 로고    scopus 로고
    • Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation
    • Zaiss MM, Sarter K, Hess A, et al. Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum 2010; 62: 2328-2338.
    • (2010) Arthritis Rheum , vol.62 , pp. 2328-2338
    • Zaiss, M.M.1    Sarter, K.2    Hess, A.3
  • 16
    • 79958279325 scopus 로고    scopus 로고
    • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
    • Fujisaki J, Wu J, Carlson AL, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature 2011; 474: 216-219.
    • (2011) Nature , vol.474 , pp. 216-219
    • Fujisaki, J.1    Wu, J.2    Carlson, A.L.3
  • 17
    • 34548058081 scopus 로고    scopus 로고
    • Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions
    • Kiesel J, Miller C, Abu-Amer Y, Aurora R., Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions. Dev Dyn 2007; 236: 2181-2197.
    • (2007) Dev Dyn , vol.236 , pp. 2181-2197
    • Kiesel, J.1    Miller, C.2    Abu-Amer, Y.3    Aurora, R.4
  • 18
    • 77955475327 scopus 로고    scopus 로고
    • Cross talk between the bone and immune systems: Osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells
    • Li H, Hong S, Qian J, Zheng Y, Yang J, Yi Q., Cross talk between the bone and immune systems: Osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells. Blood 2010; 116: 210-217.
    • (2010) Blood , vol.116 , pp. 210-217
    • Li, H.1    Hong, S.2    Qian, J.3    Zheng, Y.4    Yang, J.5    Yi, Q.6
  • 20
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998; 95: 3597-3602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 21
    • 0032400933 scopus 로고    scopus 로고
    • OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40
    • Yun TJ, Chaudhary PM, Shu GL, et al. OPG/FDCR-1, a TNF receptor family member, is expressed in lymphoid cells and is up-regulated by ligating CD40. J Immunol 1998; 161: 6113-6121.
    • (1998) J Immunol , vol.161 , pp. 6113-6121
    • Yun, T.J.1    Chaudhary, P.M.2    Shu, G.L.3
  • 22
    • 34047131111 scopus 로고    scopus 로고
    • Ovariectomy-induced bone loss occurs independently of B cells
    • Li Y, Li A, Yang X, Weitzmann MN., Ovariectomy-induced bone loss occurs independently of B cells. J Cell Biochem 2007; 100: 1370-1375.
    • (2007) J Cell Biochem , vol.100 , pp. 1370-1375
    • Li, Y.1    Li, A.2    Yang, X.3    Weitzmann, M.N.4
  • 23
    • 84865446399 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss
    • Onal M, Xiong J, Chen X, et al. Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. J Biol Chem 2012; 287: 29851-29860.
    • (2012) J Biol Chem , vol.287 , pp. 29851-29860
    • Onal, M.1    Xiong, J.2    Chen, X.3
  • 24
    • 33646396235 scopus 로고    scopus 로고
    • Estrogen deficiency and bone loss: An inflammatory tale
    • Weitzmann MN, Pacifici R., Estrogen deficiency and bone loss: An inflammatory tale. J Clin Invest 2006; 116: 1186-1194.
    • (2006) J Clin Invest , vol.116 , pp. 1186-1194
    • Weitzmann, M.N.1    Pacifici, R.2
  • 25
    • 34548274444 scopus 로고    scopus 로고
    • Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts
    • Nakamura T, Imai Y, Matsumoto T, et al. Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell 2007; 130: 811-823.
    • (2007) Cell , vol.130 , pp. 811-823
    • Nakamura, T.1    Imai, Y.2    Matsumoto, T.3
  • 26
    • 38949160556 scopus 로고    scopus 로고
    • Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival
    • Krum SA, Miranda-Carboni GA, Hauschka PV, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J 2008; 27: 535-545.
    • (2008) EMBO J , vol.27 , pp. 535-545
    • Krum, S.A.1    Miranda-Carboni, G.A.2    Hauschka, P.V.3
  • 27
    • 75149129597 scopus 로고    scopus 로고
    • From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis
    • Manolagas SC., From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis. Endocr Rev 2010; 31: 266-300.
    • (2010) Endocr Rev , vol.31 , pp. 266-300
    • Manolagas, S.C.1
  • 28
    • 0032080656 scopus 로고    scopus 로고
    • Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption
    • Jilka RL, Takahashi K, Munshi M, Williams DC, Roberson PK, Manolagas SC., Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption. J Clin invest 1998; 101: 1942-1950.
    • (1998) J Clin Invest , vol.101 , pp. 1942-1950
    • Jilka, R.L.1    Takahashi, K.2    Munshi, M.3    Williams, D.C.4    Roberson, P.K.5    Manolagas, S.C.6
  • 29
    • 0035057030 scopus 로고    scopus 로고
    • Attenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17beta-estradiol
    • Di Gregorio GB, Yamamoto M, Ali AA, et al. Attenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17beta-estradiol. J Clin Invest 2001; 107: 803-812.
    • (2001) J Clin Invest , vol.107 , pp. 803-812
    • Di Gregorio, G.B.1    Yamamoto, M.2    Ali, A.A.3
  • 30
    • 0035831020 scopus 로고    scopus 로고
    • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
    • Kousteni S, Bellido T, Plotkin LI, et al. Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity. Cell 2001; 104: 719-730.
    • (2001) Cell , vol.104 , pp. 719-730
    • Kousteni, S.1    Bellido, T.2    Plotkin, L.I.3
  • 31
    • 0038819062 scopus 로고    scopus 로고
    • Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids
    • Kousteni S, Han L, Chen JR, et al. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest 2003; 111: 1651-1664.
    • (2003) J Clin Invest , vol.111 , pp. 1651-1664
    • Kousteni, S.1    Han, L.2    Chen, J.R.3
  • 32
    • 0033708837 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha
    • Cenci S, Weitzmann MN, Roggia C, et al. Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest 2000; 106: 1229-1237.
    • (2000) J Clin Invest , vol.106 , pp. 1229-1237
    • Cenci, S.1    Weitzmann, M.N.2    Roggia, C.3
  • 33
    • 0035923727 scopus 로고    scopus 로고
    • Up-regulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo
    • Roggia C, Gao Y, Cenci S, et al. Up-regulation of TNF-producing T cells in the bone marrow: A key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci USA 2001; 98: 13960-13965.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13960-13965
    • Roggia, C.1    Gao, Y.2    Cenci, S.3
  • 34
    • 9344241405 scopus 로고    scopus 로고
    • Estrogen prevents bone loss through transforming growth factor {beta} signaling in T cells
    • Gao Y, Qian W-P, Dark K, et al. Estrogen prevents bone loss through transforming growth factor {beta} signaling in T cells. Proc Natl Acad Sci USA 2004; 16618-16623.
    • (2004) Proc Natl Acad Sci USA , pp. 16618-16623
    • Gao, Y.1    Qian, W.-P.2    Dark, K.3
  • 35
    • 33845981069 scopus 로고    scopus 로고
    • IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation
    • Gao Y, Grassi F, Ryan MR, et al. IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation. J Clin Invest 2007; 117: 122-132.
    • (2007) J Clin Invest , vol.117 , pp. 122-132
    • Gao, Y.1    Grassi, F.2    Ryan, M.R.3
  • 36
    • 49949119153 scopus 로고    scopus 로고
    • Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents
    • Yamaza T, Miura Y, Bi Y, et al. Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. PLoS ONE 2008; 3: e2615.
    • (2008) PLoS ONE , vol.3
    • Yamaza, T.1    Miura, Y.2    Bi, Y.3
  • 37
    • 35448995621 scopus 로고    scopus 로고
    • Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation
    • Grassi F, Tell G, Robbie-Ryan M, et al. Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation. Proc Natl Acad Sci USA 2007; 104: 15087-15092.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15087-15092
    • Grassi, F.1    Tell, G.2    Robbie-Ryan, M.3
  • 38
    • 33846017422 scopus 로고    scopus 로고
    • T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy
    • Lee SK, Kadono Y, Okada F, et al. T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy. J Bone Miner Res 2006; 21: 1704-1712.
    • (2006) J Bone Miner Res , vol.21 , pp. 1704-1712
    • Lee, S.K.1    Kadono, Y.2    Okada, F.3
  • 39
    • 9344241405 scopus 로고    scopus 로고
    • Estrogen prevents bone loss through transforming growth factor beta signaling in T cells
    • Gao Y, Qian WP, Dark K, et al. Estrogen prevents bone loss through transforming growth factor beta signaling in T cells. Proc Natl Acad Sci USA 2004; 101: 16618-16623.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16618-16623
    • Gao, Y.1    Qian, W.P.2    Dark, K.3
  • 40
    • 33744747955 scopus 로고    scopus 로고
    • IL-7 drives T cell-mediated bone loss following ovariectomy
    • Robbie-Ryan M, Pacifici R, Weitzmann MN., IL-7 drives T cell-mediated bone loss following ovariectomy. Ann N Y Acad Sci 2006; 1068: 348-351.
    • (2006) Ann N y Acad Sci , vol.1068 , pp. 348-351
    • Robbie-Ryan, M.1    Pacifici, R.2    Weitzmann, M.N.3
  • 41
    • 84863710982 scopus 로고    scopus 로고
    • IL-17 mediates estrogen-deficient osteoporosis
    • DeSelm C, Takahata Y, Chappel J, et al. IL-17 mediates estrogen-deficient osteoporosis. Cell Biochem 2012; 113: 2895-2902.
    • (2012) Cell Biochem , vol.113 , pp. 2895-2902
    • Deselm, C.1    Takahata, Y.2    Chappel, J.3
  • 42
    • 80052688903 scopus 로고    scopus 로고
    • Estrogen receptor alpha signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis
    • Lelu K, Laffont S, Delpy L, et al. Estrogen receptor alpha signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis. J Immunol 2011; 187: 2386-2393.
    • (2011) J Immunol , vol.187 , pp. 2386-2393
    • Lelu, K.1    Laffont, S.2    Delpy, L.3
  • 43
    • 70350545726 scopus 로고    scopus 로고
    • A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss
    • Goswami J, Hernandez-Santos N, Zuniga LA, Gaffen SL., A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss. Eur J Immunol 2009; 39: 2831-2839.
    • (2009) Eur J Immunol , vol.39 , pp. 2831-2839
    • Goswami, J.1    Hernandez-Santos, N.2    Zuniga, L.A.3    Gaffen, S.L.4
  • 44
    • 84863710982 scopus 로고    scopus 로고
    • IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner
    • DeSelm CJ, Takahata Y, Warren J, et al. IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner. J Cell Biochem 2012; 113: 2895-2902.
    • (2012) J Cell Biochem , vol.113 , pp. 2895-2902
    • Deselm, C.J.1    Takahata, Y.2    Warren, J.3
  • 45
    • 37349033910 scopus 로고    scopus 로고
    • Induction of regulatory T cells by physiological level estrogen
    • Tai P, Wang J, Jin H, et al. Induction of regulatory T cells by physiological level estrogen. J Cell Physiol 2008; 214: 456-464.
    • (2008) J Cell Physiol , vol.214 , pp. 456-464
    • Tai, P.1    Wang, J.2    Jin, H.3
  • 46
    • 79959435355 scopus 로고    scopus 로고
    • Daidzein prevents the increase in CD4CD28null T cells and B lymphopoesis in ovariectomized mice: A key mechanism for anti-osteoclastogenic effect
    • Tyagi AM, Srivastava K, Sharan K, Yadav D, Maurya R, Singh D., Daidzein prevents the increase in CD4CD28null T cells and B lymphopoesis in ovariectomized mice: A key mechanism for anti-osteoclastogenic effect. PLoS ONE 2011; 6: e21216.
    • (2011) PLoS ONE , vol.6
    • Tyagi, A.M.1    Srivastava, K.2    Sharan, K.3    Yadav, D.4    Maurya, R.5    Singh, D.6
  • 47
    • 44949083462 scopus 로고    scopus 로고
    • Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis
    • D'Amelio P, Grimaldi A, Di Bella S, et al. Estrogen deficiency increases osteoclastogenesis up-regulating T cells activity: A key mechanism in osteoporosis. Bone 2008; 43: 92-100.
    • (2008) Bone , vol.43 , pp. 92-100
    • D'Amelio, P.1    Grimaldi, A.2    Di Bella, S.3
  • 48
    • 0041836267 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator
    • Cenci S, Toraldo G, Weitzmann MN, et al. Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci USA 2003; 100: 10405-10410.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10405-10410
    • Cenci, S.1    Toraldo, G.2    Weitzmann, M.N.3
  • 49
    • 33646423122 scopus 로고    scopus 로고
    • Ovariectomy increases the formation of T cell niches at the resorption surfaces
    • Abs
    • Grassi F, Pacifici R., Ovariectomy increases the formation of T cell niches at the resorption surfaces. J Bone Min Res 2005; 20 (Suppl 1): Abs.
    • (2005) J Bone Min Res , vol.20 , Issue.SUPPL. 1
    • Grassi, F.1    Pacifici, R.2
  • 50
    • 0142186681 scopus 로고    scopus 로고
    • A crucial role for thiol antioxidants in estrogen-deficiency bone loss
    • Lean JM, Davies JT, Fuller K, et al. A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J Clin Invest 2003; 112: 915-923.
    • (2003) J Clin Invest , vol.112 , pp. 915-923
    • Lean, J.M.1    Davies, J.T.2    Fuller, K.3
  • 51
    • 24044460427 scopus 로고    scopus 로고
    • Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats
    • Muthusami S, Ramachandran I, Muthusamy B, et al. Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats. Clin Chim Acta 2005; 360: 81-86.
    • (2005) Clin Chim Acta , vol.360 , pp. 81-86
    • Muthusami, S.1    Ramachandran, I.2    Muthusamy, B.3
  • 52
    • 84857441459 scopus 로고    scopus 로고
    • Premature T cell senescence in ovx mice is inhibited by repletion of estrogen and medicarpin: A possible mechanism for alleviating bone loss
    • Tyagi AM, Srivastava K, Kureel J, et al. Premature T cell senescence in ovx mice is inhibited by repletion of estrogen and medicarpin: A possible mechanism for alleviating bone loss. Osteoporos Int 2011; 23: 1151-1161.
    • (2011) Osteoporos Int , vol.23 , pp. 1151-1161
    • Tyagi, A.M.1    Srivastava, K.2    Kureel, J.3
  • 54
    • 0038360770 scopus 로고    scopus 로고
    • Marked decrease in plasma antioxidants in aged osteoporotic women: Results of a cross-sectional study
    • Maggio D, Barabani M, Pierandrei M, et al. Marked decrease in plasma antioxidants in aged osteoporotic women: Results of a cross-sectional study. J Clin Endocrinol Metab 2003; 88: 1523-1527.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1523-1527
    • Maggio, D.1    Barabani, M.2    Pierandrei, M.3
  • 55
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel T., Oxidant signals and oxidative stress. Curr Opin Cell Biol 2003; 15: 247-254.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 247-254
    • Finkel, T.1
  • 56
    • 0036618347 scopus 로고    scopus 로고
    • Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase
    • Ozaki M, Suzuki S, Irani K., Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase. FASEB J 2002; 16: 889-890.
    • (2002) FASEB J , vol.16 , pp. 889-890
    • Ozaki, M.1    Suzuki, S.2    Irani, K.3
  • 57
    • 34848878406 scopus 로고    scopus 로고
    • Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids
    • Almeida M, Han L, Martin-Millan M, et al. Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids. J Biol Chem 2007; 282: 27285-27297.
    • (2007) J Biol Chem , vol.282 , pp. 27285-27297
    • Almeida, M.1    Han, L.2    Martin-Millan, M.3
  • 58
    • 77953392432 scopus 로고    scopus 로고
    • Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha
    • Almeida M, Martin-Millan M, Ambrogini E, et al. Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha. J Bone Miner Res 2010; 25: 769-781.
    • (2010) J Bone Miner Res , vol.25 , pp. 769-781
    • Almeida, M.1    Martin-Millan, M.2    Ambrogini, E.3
  • 59
    • 75149165271 scopus 로고    scopus 로고
    • The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone
    • Martin-Millan M, Almeida M, Ambrogini E, et al. The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone. Mol Endocrinol 2010; 24: 323-334.
    • (2010) Mol Endocrinol , vol.24 , pp. 323-334
    • Martin-Millan, M.1    Almeida, M.2    Ambrogini, E.3
  • 60
    • 15044359360 scopus 로고    scopus 로고
    • Redox imbalance induced by contact sensitizers triggers the maturation of dendritic cells
    • Mizuashi M, Ohtani T, Nakagawa S, Aiba S., Redox imbalance induced by contact sensitizers triggers the maturation of dendritic cells. J Invest Dermatol 2005; 124: 579-586.
    • (2005) J Invest Dermatol , vol.124 , pp. 579-586
    • Mizuashi, M.1    Ohtani, T.2    Nakagawa, S.3    Aiba, S.4
  • 61
    • 0345435976 scopus 로고    scopus 로고
    • Reactive oxygen species activate human peripheral blood dendritic cells
    • Rutault K, Alderman C, Chain BM, Katz DR., Reactive oxygen species activate human peripheral blood dendritic cells. Free Radic Biol Med 1999; 26: 232-238.
    • (1999) Free Radic Biol Med , vol.26 , pp. 232-238
    • Rutault, K.1    Alderman, C.2    Chain, B.M.3    Katz, D.R.4
  • 62
    • 22944444543 scopus 로고    scopus 로고
    • Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells
    • Maemura K, Zheng Q, Wada T, et al. Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells. Immunol Cell Biol 2005; 83: 336-343.
    • (2005) Immunol Cell Biol , vol.83 , pp. 336-343
    • Maemura, K.1    Zheng, Q.2    Wada, T.3
  • 63
    • 0037442168 scopus 로고    scopus 로고
    • Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory t cells
    • Vosters O, Neve J, De Wit D, Willems F, Goldman M, Verhasselt V., Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory t cells. Transplantation 2003; 75: 383-389.
    • (2003) Transplantation , vol.75 , pp. 383-389
    • Vosters, O.1    Neve, J.2    De Wit, D.3    Willems, F.4    Goldman, M.5    Verhasselt, V.6
  • 64
    • 0033106338 scopus 로고    scopus 로고
    • N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-kappaB inhibition
    • Verhasselt V, Vanden Berghe W, Vanderheyde N, Willems F, Haegeman G, Goldman M., N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-kappaB inhibition. J Immunol 1999; 162: 2569-2574.
    • (1999) J Immunol , vol.162 , pp. 2569-2574
    • Verhasselt, V.1    Vanden Berghe, W.2    Vanderheyde, N.3    Willems, F.4    Haegeman, G.5    Goldman, M.6
  • 65
    • 11144248825 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants
    • Jagger CJ, Lean JM, Davies JT, Chambers TJ., Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants. Endocrinology 2005; 146: 113-118.
    • (2005) Endocrinology , vol.146 , pp. 113-118
    • Jagger, C.J.1    Lean, J.M.2    Davies, J.T.3    Chambers, T.J.4
  • 66
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal IS, Flavell RA., CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 1998; 16: 111-135.
    • (1998) Annu Rev Immunol , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 67
  • 68
    • 0036130828 scopus 로고    scopus 로고
    • CD40L stabilizes arterial thrombi by a beta3 integrin-dependent mechanism
    • Andre P, Prasad KS, Denis CV, et al. CD40L stabilizes arterial thrombi by a beta3 integrin-dependent mechanism. Nat Med 2002; 8: 247-252.
    • (2002) Nat Med , vol.8 , pp. 247-252
    • Andre, P.1    Prasad, K.S.2    Denis, C.V.3
  • 69
    • 34247161366 scopus 로고    scopus 로고
    • CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling
    • Leveille C, Bouillon M, Guo W, et al. CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling. J Biol Chem 2007; 282: 5143-5151.
    • (2007) J Biol Chem , vol.282 , pp. 5143-5151
    • Leveille, C.1    Bouillon, M.2    Guo, W.3
  • 70
    • 0038410098 scopus 로고    scopus 로고
    • CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4
    • Ahuja SS, Zhao S, Bellido T, Plotkin LI, Jimenez F, Bonewald LF., CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4. Endocrinology 2003; 144: 1761-1769.
    • (2003) Endocrinology , vol.144 , pp. 1761-1769
    • Ahuja, S.S.1    Zhao, S.2    Bellido, T.3    Plotkin, L.I.4    Jimenez, F.5    Bonewald, L.F.6
  • 71
    • 48149095459 scopus 로고    scopus 로고
    • T cells potentiate PTH-induced cortical bone loss through CD40L signaling
    • Gao Y, Wu X, Terauchi M, et al. T cells potentiate PTH-induced cortical bone loss through CD40L signaling. Cell Metab 2008; 8: 132-145.
    • (2008) Cell Metab , vol.8 , pp. 132-145
    • Gao, Y.1    Wu, X.2    Terauchi, M.3
  • 72
    • 34247633506 scopus 로고    scopus 로고
    • Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis
    • Lopez-Granados E, Temmerman ST, Wu L, et al. Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis. Proc Natl Acad Sci USA 2007; 104: 5056-5061.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5056-5061
    • Lopez-Granados, E.1    Temmerman, S.T.2    Wu, L.3
  • 73
    • 0035837553 scopus 로고    scopus 로고
    • Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
    • Neer RM, Arnaud CD, Zanchetta JR, et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 2001; 344: 1434-1441.
    • (2001) N Engl J Med , vol.344 , pp. 1434-1441
    • Neer, R.M.1    Arnaud, C.D.2    Zanchetta, J.R.3
  • 74
    • 34548306408 scopus 로고    scopus 로고
    • Mechanisms of anabolic therapies for osteoporosis
    • Canalis E, Giustina A, Bilezikian JP., Mechanisms of anabolic therapies for osteoporosis. N Engl J Med 2007; 357: 905-916.
    • (2007) N Engl J Med , vol.357 , pp. 905-916
    • Canalis, E.1    Giustina, A.2    Bilezikian, J.P.3
  • 75
    • 77957891185 scopus 로고    scopus 로고
    • Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss
    • Tawfeek H, Bedi B, Li JY, et al. Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss. PLoS ONE 2010; 5: e12290.
    • (2010) PLoS ONE , vol.5
    • Tawfeek, H.1    Bedi, B.2    Li, J.Y.3
  • 76
    • 69149106680 scopus 로고    scopus 로고
    • T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling
    • Terauchi M, Li JY, Bedi B, et al. T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab 2009; 10: 229-240.
    • (2009) Cell Metab , vol.10 , pp. 229-240
    • Terauchi, M.1    Li, J.Y.2    Bedi, B.3
  • 77
    • 84863345866 scopus 로고    scopus 로고
    • Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH
    • Bedi B, Li JY, Tawfeek H, et al. Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH. Proc Natl Acad Sci USA 2012; 109: E725-E733.
    • (2012) Proc Natl Acad Sci USA , vol.109
    • Bedi, B.1    Li, J.Y.2    Tawfeek, H.3
  • 78
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
    • Bellido T, Ali AA, Gubrij I, et al. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 2005; 146: 4577-4583.
    • (2005) Endocrinology , vol.146 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3
  • 79
    • 21844467220 scopus 로고    scopus 로고
    • SOST is a target gene for PTH in bone
    • Keller H, Kneissel M., SOST is a target gene for PTH in bone. Bone 2005; 37: 148-158.
    • (2005) Bone , vol.37 , pp. 148-158
    • Keller, H.1    Kneissel, M.2
  • 80
    • 51449111663 scopus 로고    scopus 로고
    • Control of bone mass and remodeling by PTH receptor signaling in osteocytes
    • O'Brien CA, Plotkin LI, Galli C, et al. Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS ONE 2008; 3: e2942.
    • (2008) PLoS ONE , vol.3
    • O'Brien, C.A.1    Plotkin, L.I.2    Galli, C.3
  • 81
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Mendez-Ferrer S, Michurina TV, Ferraro F, et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 2010; 466: 829-834.
    • (2010) Nature , vol.466 , pp. 829-834
    • Mendez-Ferrer, S.1    Michurina, T.V.2    Ferraro, F.3
  • 82
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003; 425: 841-846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3
  • 83
    • 77951935429 scopus 로고    scopus 로고
    • Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases
    • Straub RH, Cutolo M, Buttgereit F, Pongratz G., Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases. J Intern Med 2010; 267: 543-560.
    • (2010) J Intern Med , vol.267 , pp. 543-560
    • Straub, R.H.1    Cutolo, M.2    Buttgereit, F.3    Pongratz, G.4
  • 84
    • 78649334801 scopus 로고    scopus 로고
    • Concepts of evolutionary medicine and energy regulation contribute to the etiology of systemic chronic inflammatory diseases
    • Straub RH., Concepts of evolutionary medicine and energy regulation contribute to the etiology of systemic chronic inflammatory diseases. Brain Behav Immun 2011; 25: 1-5.
    • (2011) Brain Behav Immun , vol.25 , pp. 1-5
    • Straub, R.H.1
  • 85
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • Feske S., Calcium signalling in lymphocyte activation and disease. Nat Rev 2007; 7: 690-702.
    • (2007) Nat Rev , vol.7 , pp. 690-702
    • Feske, S.1
  • 86
    • 84862585967 scopus 로고    scopus 로고
    • Evolutionary medicine and chronic inflammatory state-known and new concepts in pathophysiology
    • Straub RH., Evolutionary medicine and chronic inflammatory state-known and new concepts in pathophysiology. J Mol Med (Berl) 2012; 90: 523-534.
    • (2012) J Mol Med (Berl) , vol.90 , pp. 523-534
    • Straub, R.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.