Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

EMBO Journal

Volumn 27, Issue 3, 2008, Pages 535-545

  Krum, Susan A ^a   Miranda Carboni, Gustavo A ^b   Hauschka, Peter V ^c   Carroll, Jason S ^a,e   Lane, Timothy F ^b   Freedman, Leonard P ^d   Brown, Myles ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d PFIZER INC   (United States)

^e IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Bone; Estrogen; Fas ligand; Osteoblast; Osteoclast

Indexed keywords

ESTRADIOL; FAS LIGAND; RALOXIFENE; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; ENHANCER REGION; ESTROGEN ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOPOROSIS; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTECTION; PROTEIN INDUCTION; STEM CELL; UPREGULATION;

3T3 CELLS; ANIMALS; ANTIGENS, CD95; BONE AND BONES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL SURVIVAL; COCULTURE TECHNIQUES; ESTROGENS; FAS LIGAND PROTEIN; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOBLASTS; OSTEOCLASTS;

EID: 38949160556     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601984     Document Type: Article

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