Mechanism of dual specificity kinase activity of DYRK1A

FEBS Journal

Volumn 280, Issue 18, 2013, Pages 4495-4511

  Walte, Agnes ^a   Rüben, Katharina ^a   Birner Gruenberger, Ruth ^b   Preisinger, Christian ^a   Bamberg Lemper, Simone ^a   Hilz, Nikolaus ^c   Bracher, Franz ^c   Becker, Walter ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

DYRK; HIPK2; iodotubercidin; kinase inhibitors; tyrosine autophosphorylation

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1A; DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 2; PROTEIN SERINE THREONINE KINASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; IN VITRO STUDY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING;

DYRK; HIPK2; IODOTUBERCIDIN; KINASE INHIBITORS; TYROSINE AUTOPHOSPHORYLATION;

ANIMALS; BIOCATALYSIS; ESCHERICHIA COLI; HELA CELLS; HUMANS; KINETICS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; RECOMBINANT PROTEINS; SERINE; SUBSTRATE SPECIFICITY; THERMODYNAMICS; THREONINE; TRANSFECTION; TYROSINE;

MAMMALIA;

EID: 84883448406     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12411     Document Type: Article

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