Resveratrol inhibits Kv2.2 currents through the estrogen receptor GPR30-mediated PKC pathway

American Journal of Physiology - Cell Physiology

Volumn 305, Issue 5, 2013, Pages

  Dong, Wen Hao ^a   Chen, Jia Chen ^a   He, Yan Lin ^a   Xu, Jia Jie ^a   Mei, Yan Ai ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

GPR30; Kv2.2; PKC; Resveratrol

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR 30; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV2.1; POTASSIUM CHANNEL KV2.2; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C INHIBITOR; RESVERATROL; SHAB POTASSIUM CHANNEL; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CEREBELLUM; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; GENE REPRESSION; GENETIC TRANSFECTION; GRANULE CELL; HUMAN; HUMAN CELL; MEDIATOR; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

GPR30; KV2.2; PKC; RESVERATROL;

ACTION POTENTIALS; ANIMALS; ANTIOXIDANTS; CEREBRAL CORTEX; FEMALE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; NEURONS; PATCH-CLAMP TECHNIQUES; PRIMARY CELL CULTURE; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SHAB POTASSIUM CHANNELS; SIGNAL TRANSDUCTION; STILBENES; TETRADECANOYLPHORBOL ACETATE;

EID: 84883378851     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00146.2013     Document Type: Article

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