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Volumn 154, Issue 9, 2013, Pages 3001-3007

Uncovering novel roles of nonneuronal cells in body weight homeostasis and obesity

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; CYTOKINE; EXCITATORY AMINO ACID TRANSPORTER; FATTY ACID; GHRELIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; GLUTAMINASE; GLUTAMINE; INSULIN; INSULIN RECEPTOR; LACTIC ACID; LEPTIN; LEPTIN RECEPTOR; MELANOCORTIN; MONOCARBOXYLATE TRANSPORTER; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PYRUVIC ACID; SODIUM DERIVATIVE; TUNGSTATE SODIUM; UNCLASSIFIED DRUG;

EID: 84883205286     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1303     Document Type: Review
Times cited : (26)

References (63)
  • 1
    • 84860530692 scopus 로고    scopus 로고
    • Astrocytes and disease: A neurodevelopmental perspective
    • Molofsky AV, Krencik R, Ullian EM, et al. Astrocytes and disease: a neurodevelopmental perspective. Genes Dev. 2012;26:891-907.
    • (2012) Genes Dev , vol.26 , pp. 891-907
    • Molofsky, A.V.1    Krencik, R.2    Ullian, E.M.3
  • 4
    • 77649192930 scopus 로고    scopus 로고
    • Oligodendrocytes: Biology and pathology
    • Bradl M, Lassmann H. Oligodendrocytes: biology and pathology. Acta Neuropathol. 2010;119:37-53.
    • (2010) Acta Neuropathol , vol.119 , pp. 37-53
    • Bradl, M.1    Lassmann, H.2
  • 6
    • 28944432319 scopus 로고    scopus 로고
    • Hypothalamic tanycytes: A key component of brain endocrine interaction
    • Rodríguez EM, Blázquez JL, Pastor FE, et al. Hypothalamic tanycytes: a key component of brain endocrine interaction. Int Rev Cytol. 2005;247:89-164.
    • (2005) Int Rev Cytol , vol.247 , pp. 89-164
    • Rodríguez, E.M.1    Blázquez, J.L.2    Pastor, F.E.3
  • 9
    • 84864855681 scopus 로고    scopus 로고
    • Leptin action on nonneuronal cells in the CNS: Potential clinical applications
    • Pan W, Hsuchou H, Jayaram B, et al. Leptin action on nonneuronal cells in the CNS: potential clinical applications. Ann NY Acad Sci. 2012;1264:64-71.
    • (2012) Ann NY Acad Sci , vol.1264 , pp. 64-71
    • Pan, W.1    Hsuchou, H.2    Jayaram, B.3
  • 11
    • 58849149821 scopus 로고    scopus 로고
    • Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
    • Milanski M, Degasperi G, Coop A, et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity. J Neurosci. 2009;29:359-370.
    • (2009) J Neurosci , vol.29 , pp. 359-370
    • Milanski, M.1    Degasperi, G.2    Coop, A.3
  • 12
    • 77957053600 scopus 로고    scopus 로고
    • Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity
    • Horvath TL, Sarman B, García-Cáceres C, et al. Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity. Proc Natl Acad Sci USA. 2010;107:14875-14880.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 14875-14880
    • Horvath, T.L.1    Sarman, B.2    García-Cáceres, C.3
  • 13
    • 84855459760 scopus 로고    scopus 로고
    • Obesity is associated with hypothalamic injury in rodents and humans
    • Thaler JP, Yi CX, Schur EA, et al. Obesity is associated with hypothalamic injury in rodents and humans. J Clin Invest. 2012;122: 153-162.
    • (2012) J Clin Invest , vol.122 , pp. 153-162
    • Thaler, J.P.1    Yi, C.X.2    Schur, E.A.3
  • 15
    • 84877135040 scopus 로고    scopus 로고
    • Astrogliosis in the brain of obese Zucker rat: A model of metabolic syndrome
    • Tomassoni D, Nwankwo IE, Gabrielli MG, et al. Astrogliosis in the brain of obese Zucker rat: a model of metabolic syndrome. Neurosci Lett. 2013;543:136-141.
    • (2013) Neurosci Lett , vol.543 , pp. 136-141
    • Tomassoni, D.1    Nwankwo, I.E.2    Gabrielli, M.G.3
  • 16
    • 0022653095 scopus 로고
    • Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats
    • Garcia-Segura LM, Baetens D, Naftolin F. Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats. Brain Res. 1986;366:131-136.
    • (1986) Brain Res , vol.366 , pp. 131-136
    • Garcia-Segura, L.M.1    Baetens, D.2    Naftolin, F.3
  • 17
    • 0022527705 scopus 로고
    • Oxytocin induces morphological plasticity in the adult hypothalamo-neurohypophysial system
    • Theodosis DT, Montagnese C, Rodriguez F, Vincent JD, Poulain DA. Oxytocin induces morphological plasticity in the adult hypothalamo-neurohypophysial system. Nature. 1986;322:738-740.
    • (1986) Nature , vol.322 , pp. 738-740
    • Theodosis, D.T.1    Montagnese, C.2    Rodriguez, F.3    Vincent, J.D.4    Poulain, D.A.5
  • 18
    • 1842529267 scopus 로고    scopus 로고
    • Rapid rewiring of arcuate nucleus feeding circuits by leptin
    • Pinto S, Roseberry AG, Liu H, Diano S, et al. Rapid rewiring of arcuate nucleus feeding circuits by leptin. Science. 2004;304:110-115.
    • (2004) Science , vol.304 , pp. 110-115
    • Pinto, S.1    Roseberry, A.G.2    Liu, H.3    Diano, S.4
  • 19
  • 20
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • Bouret S, Draper SJ, Simerly RB. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science. 2004;304:63-64.
    • (2004) Science , vol.304 , pp. 63-64
    • Bouret, S.1    Draper, S.J.2    Simerly, R.B.3
  • 21
    • 84868629649 scopus 로고    scopus 로고
    • Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes
    • Fuente-Martín E, García-Cáceres C, Granado M, et al. Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes. J Clin Invest. 2012;11:3900-3913.
    • (2012) J Clin Invest , vol.11 , pp. 3900-3913
    • Fuente-Martín, E.1    García-Cáceres, C.2    Granado, M.3
  • 22
  • 23
    • 79959428713 scopus 로고    scopus 로고
    • Metabolic sensing and the brain: Who, what, where, and how?
    • Levin BE, MagnanC, Dunn-Meynell A, Le Foll C. Metabolic sensing and the brain: who, what, where, and how? Endocrinology. 2011; 152:2552-2557.
    • (2011) Endocrinology , vol.152 , pp. 2552-2557
    • Levin, B.E.1    Magnan, C.2    Dunn-Meynell, A.3    Le Foll, C.4
  • 24
    • 65249150732 scopus 로고    scopus 로고
    • Obesity induces functional astrocytic leptin receptors in hypothalamus
    • Hsuchou H, He Y, Kastin AJ, et al. Obesity induces functional astrocytic leptin receptors in hypothalamus. Brain. 2009;132:889-902.
    • (2009) Brain , vol.132 , pp. 889-902
    • Hsuchou, H.1    He, Y.2    Kastin, A.J.3
  • 25
    • 79955431010 scopus 로고    scopus 로고
    • Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels
    • García-Cáceres C, Fuente-Martín E, Burgos-Ramos E, et al. Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels. Endocrinology. 2011;152: 1809-1818.
    • (2011) Endocrinology , vol.152 , pp. 1809-1818
    • García-Cáceres, C.1    Fuente-Martín, E.2    Burgos-Ramos, E.3
  • 26
    • 1442276966 scopus 로고    scopus 로고
    • Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons
    • Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE. Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes. 2004;53:549-559.
    • (2004) Diabetes , vol.53 , pp. 549-559
    • Kang, L.1    Routh, V.H.2    Kuzhikandathil, E.V.3    Gaspers, L.D.4    Levin, B.E.5
  • 27
    • 34548207654 scopus 로고    scopus 로고
    • Brain glucose sensing, counterregulation, and energy homeostasis
    • Marty N, Dallaporta M, Thorens B. Brain glucose sensing, counterregulation, and energy homeostasis. Physiology (Bethesda). 2007;22:241-251.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 241-251
    • Marty, N.1    Dallaporta, M.2    Thorens, B.3
  • 28
    • 33847720313 scopus 로고    scopus 로고
    • Hypothalamic fatty acid metabolism: A housekeeping pathway that regulates food intake
    • Lopez M, Lelliott CJ, Vidal-Puig A. Hypothalamic fatty acid metabolism: a housekeeping pathway that regulates food intake. Bioessays. 2007;29:248-261.
    • (2007) Bioessays , vol.29 , pp. 248-261
    • Lopez, M.1    Lelliott, C.J.2    Vidal-Puig, A.3
  • 29
    • 67649505383 scopus 로고    scopus 로고
    • Up-regulation of apolipoprotein e by leptin in the hypothalamus of mice and rats
    • Shen, Tso P, Wang DQ, et al. Up-regulation of apolipoprotein E by leptin in the hypothalamus of mice and rats. Physiol Behav. 2009; 98:223-228.
    • (2009) Physiol Behav , vol.98 , pp. 223-228
    • Shen Tso, P.1    Wang, D.Q.2
  • 30
    • 0022350033 scopus 로고
    • Apolipoprotein e associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM. Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin Invest. 1985;76:1501-1513.
    • (1985) J Clin Invest , vol.76 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3    Mahley, R.W.4    Taylor, J.M.5
  • 31
    • 80053447077 scopus 로고    scopus 로고
    • Apolipoprotein e reduces food intake via PI3K/Akt signaling pathway in the hypothalamus
    • Shen L, Wang DQ, Tso P, Jandacek RJ, Woods SC, Liu M. Apolipoprotein E reduces food intake via PI3K/Akt signaling pathway in the hypothalamus. Physiol Behav. 2011;105:124-128.
    • (2011) Physiol Behav , vol.105 , pp. 124-128
    • Shen, L.1    Wang, D.Q.2    Tso, P.3    Jandacek, R.J.4    Woods, S.C.5    Liu, M.6
  • 32
    • 0031714313 scopus 로고    scopus 로고
    • Role of carnitine palmitoyltransferase i in the control of ketogenesis in primary cultures of rat astrocytes
    • Blázquez C, Sánchez C, Velasco G, Guzmán M. Role of carnitine palmitoyltransferase I in the control of ketogenesis in primary cultures of rat astrocytes. J Neurochem. 1998;71:1597-1606.
    • (1998) J Neurochem , vol.71 , pp. 1597-1606
    • Blázquez, C.1    Sánchez, C.2    Velasco, G.3    Guzmán, M.4
  • 33
    • 79959763844 scopus 로고    scopus 로고
    • Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats
    • Park S, Kim da S, Daily JW. Central infusion of ketone bodies modulates body weight and hepatic insulin sensitivity by modifying hypothalamic leptin and insulin signaling pathways in type 2 diabetic rats. Brain Res. 2011;1401:95-103.
    • (2011) Brain Res , vol.1401 , pp. 95-103
    • Park, S.1    Kim Da, S.2    Daily, J.W.3
  • 34
    • 84874156024 scopus 로고    scopus 로고
    • Regional astrogliosis in the mouse hypothalamus in response to obesity
    • Buckman LB, Thompson MM, Moreno HN, Ellacott KL. Regional astrogliosis in the mouse hypothalamus in response to obesity. J Comp Neurol. 2013;521:1322-1333.
    • (2013) J Comp Neurol , vol.521 , pp. 1322-1333
    • Buckman, L.B.1    Thompson, M.M.2    Moreno, H.N.3    Ellacott, K.L.4
  • 35
    • 84862650144 scopus 로고    scopus 로고
    • Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences
    • Higuchi S, Irie K, Yamaguchi R, et al. Hypothalamic 2- arachidonoylglycerol regulates multistage process of high-fat diet preferences. Plos One. 2012;7:e38609.
    • (2012) Plos One , vol.7
    • Higuchi, S.1    Irie, K.2    Yamaguchi, R.3
  • 36
    • 84863609129 scopus 로고    scopus 로고
    • Anti-obesity sodium tungstate treatment triggers axonal and glial plasticity in hypothalamic feeding centers
    • Amigó-Correig M, Barceló-Batllori S, Soria G, et al. Anti-obesity sodium tungstate treatment triggers axonal and glial plasticity in hypothalamic feeding centers. PloS ONE. 2012;7:e39087.
    • (2012) PloS ONE , vol.7
    • Amigó-Correig, M.1    Barceló-Batllori, S.2    Soria, G.3
  • 37
    • 79955805254 scopus 로고    scopus 로고
    • Astrocytes modulate distribution and neuronal signaling of leptin in the hypothalamus of obese Avy mice
    • Pan W, Hsuchou H, Xu C,WuX, Bouret SG, Kastin AJ. Astrocytes modulate distribution and neuronal signaling of leptin in the hypothalamus of obese Avy mice. J Mol Neurosci. 2011;43:478-484.
    • (2011) J Mol Neurosci , vol.43 , pp. 478-484
    • Pan, W.1    Hsuchou, H.2    Cwux, X.3    Bouret, S.G.4    Kastin, A.J.5
  • 38
    • 79959879208 scopus 로고    scopus 로고
    • Central insulin and leptin-mediated autonomic control of glucose homeostasis
    • Marino JS, Xu Y, Hill JW. Central insulin and leptin-mediated autonomic control of glucose homeostasis. Trends Endocrinol Metab. 2011;22:275-285.
    • (2011) Trends Endocrinol Metab , vol.22 , pp. 275-285
    • Marino, J.S.1    Xu, Y.2    Hill, J.W.3
  • 39
    • 84857410355 scopus 로고    scopus 로고
    • Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/-mice
    • Burgos-Ramos E, González-Rodríguez A, Canelles S, et al. Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/-mice. Endocrinology. 2012;153:1129-1140.
    • (2012) Endocrinology , vol.153 , pp. 1129-1140
    • Burgos-Ramos, E.1    González-Rodríguez, A.2    Canelles, S.3
  • 41
    • 84863477910 scopus 로고    scopus 로고
    • Leptin affects insulin action in astrocytes and impairs insulin-mediated physical activity
    • Sartorius T, Heni M, Tschritter O, et al. Leptin affects insulin action in astrocytes and impairs insulin-mediated physical activity. Cell Physiol Biochem. 2012;30:238-246.
    • (2012) Cell Physiol Biochem , vol.30 , pp. 238-246
    • Sartorius, T.1    Heni, M.2    Tschritter, O.3
  • 42
    • 84878586125 scopus 로고    scopus 로고
    • Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity
    • Jayaram B, Pan W, Wang Y, et al. Astrocytic leptin-receptor knockout mice show partial rescue of leptin resistance in diet-induced obesity. J Appl Physiol. 2013;114:734-741.
    • (2013) J Appl Physiol , vol.114 , pp. 734-741
    • Jayaram, B.1    Pan, W.2    Wang, Y.3
  • 43
    • 84862812857 scopus 로고    scopus 로고
    • Saturated long-chain fatty acids activate inflammatory signaling in astrocytes
    • Gupta S, Knight AG, Gupta S, Keller JN, Bruce-Keller AJ. Saturated long-chain fatty acids activate inflammatory signaling in astrocytes. J Neurochem. 2012;120:1060-1071.
    • (2012) J Neurochem , vol.120 , pp. 1060-1071
    • Gupta, S.1    Knight, A.G.2    Gupta, S.3    Keller, J.N.4    Bruce-Keller, A.J.5
  • 44
    • 84859717206 scopus 로고    scopus 로고
    • Innate immunity in the central nervous system
    • Ransohoff RM, Brown MA. Innate immunity in the central nervous system. J Clin Invest. 2012;122:1164-1171.
    • (2012) J Clin Invest , vol.122 , pp. 1164-1171
    • Ransohoff, R.M.1    Brown, M.A.2
  • 45
    • 77956827261 scopus 로고    scopus 로고
    • IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition
    • Ropelle ER, Flores MB, Cintra DE, et al. IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition. PLoS Biol. 2010;8:e1000465.
    • (2010) PLoS Biol , vol.8
    • Ropelle, E.R.1    Flores, M.B.2    Cintra, D.E.3
  • 46
    • 0036152683 scopus 로고    scopus 로고
    • Interleukin-6-deficient mice develop mature-onset obesity
    • Wallenius V, Wallenius K, Ahrén B, et al. Interleukin-6-deficient mice develop mature-onset obesity. Nat Med. 2002;8:75-79.
    • (2002) Nat Med , vol.8 , pp. 75-79
    • Wallenius, V.1    Wallenius, K.2    Ahrén, B.3
  • 47
    • 84860565985 scopus 로고    scopus 로고
    • Exercise protects against high-fat diet-induced hypothalamic inflammation
    • Yi CX, Al-Massadi O, Donelan E, et al. Exercise protects against high-fat diet-induced hypothalamic inflammation. Physiol Behav. 2012;106:485-490.
    • (2012) Physiol Behav , vol.106 , pp. 485-490
    • Yi, C.X.1    Al-Massadi, O.2    Donelan, E.3
  • 48
    • 0031749704 scopus 로고    scopus 로고
    • Melanocortin peptides inhibit production of proinflammatory cytokines and nitric oxide by activated microglia
    • Delgado R, Carlin A, Airaghi L, et al. Melanocortin peptides inhibit production of proinflammatory cytokines and nitric oxide by activated microglia. J Leukoc Biol. 1998;63:740-745.
    • (1998) J Leukoc Biol , vol.63 , pp. 740-745
    • Delgado, R.1    Carlin, A.2    Airaghi, L.3
  • 49
    • 84868532102 scopus 로고    scopus 로고
    • Protective role of neuropeptide y Y2 receptors in cell death and microglial response following methamphetamine injury
    • Gonçalves J, Ribeiro CF, Malva JO, Silva AP. Protective role of neuropeptide Y Y2 receptors in cell death and microglial response following methamphetamine injury. Eur J Neurosci. 2012;36: 3173-3183.
    • (2012) Eur J Neurosci , vol.36 , pp. 3173-3183
    • Gonçalves, J.1    Ribeiro, C.F.2    Malva, J.O.3    Silva, A.P.4
  • 51
    • 77950216899 scopus 로고    scopus 로고
    • Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet
    • Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL. Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology. 2010;151:1622-1632.
    • (2010) Endocrinology , vol.151 , pp. 1622-1632
    • Grayson, B.E.1    Levasseur, P.R.2    Williams, S.M.3    Smith, M.S.4    Marks, D.L.5    Grove, K.L.6
  • 52
    • 79952677635 scopus 로고    scopus 로고
    • Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition
    • Tapia-Gonzalez S, Garcia-Segura LM, Tena-Sempere M, et al. Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition. J of Neuroendocrinol. 2011;23:365-370.
    • (2011) J of Neuroendocrinol , vol.23 , pp. 365-370
    • Tapia-Gonzalez, S.1    Garcia-Segura, L.M.2    Tena-Sempere, M.3
  • 53
    • 79955008199 scopus 로고    scopus 로고
    • Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypotoxic ischemia in neonatal brain throughJNK hyperactivation
    • Tu Y-F, Tsai Y-S, Wang L-W, Wu H-C, Huang C-C, Ho C-J. Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypotoxic ischemia in neonatal brain throughJNK hyperactivation. J Neuroinflammation. 2011;8:40.
    • (2011) J Neuroinflammation , vol.8 , pp. 40
    • Tu, Y.-F.1    Tsai, Y.-S.2    Wang, L.-W.3    Wu, H.-C.4    Huang, C.-C.5    Ho, C.-J.6
  • 54
    • 34548763920 scopus 로고    scopus 로고
    • Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-κB, and p300 pathway in microglia
    • Tang CH, Lu DY, Yang RS, et al. Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-κB, and p300 pathway in microglia. J Immunol. 2007;179:1292-1302.
    • (2007) J Immunol , vol.179 , pp. 1292-1302
    • Tang, C.H.1    Lu, D.Y.2    Yang, R.S.3
  • 55
    • 77951622892 scopus 로고    scopus 로고
    • Leptin modulates cell morphology and cytokine release in microglia
    • Lafrance V, Inoue W, Kan B, Luheshi GN. Leptin modulates cell morphology and cytokine release in microglia. Brain Behav Immun. 2010;24:358-365.
    • (2010) Brain Behav Immun , vol.24 , pp. 358-365
    • Lafrance, V.1    Inoue, W.2    Kan, B.3    Luheshi, G.N.4
  • 56
    • 0042303943 scopus 로고    scopus 로고
    • Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing
    • García MA, Millán C, Balmaceda-Aguilera C, et al. Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing. J Neurochem. 2003;86:709-724.
    • (2003) J Neurochem , vol.86 , pp. 709-724
    • García, M.A.1    Millán, C.2    Balmaceda-Aguilera, C.3
  • 57
  • 58
    • 2342510308 scopus 로고    scopus 로고
    • Third ventricular alloxan reversibly impairs glucose counterregulatory responses
    • Sanders NM, Dunn-Meynell AA, Levin BE. Third ventricular alloxan reversibly impairs glucose counterregulatory responses. Diabetes. 2004;53:1230-1236.
    • (2004) Diabetes , vol.53 , pp. 1230-1236
    • Sanders, N.M.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 59
    • 0029960823 scopus 로고    scopus 로고
    • Endocrine glia: Roles of glial cells in the brain actions of steroid and thyroid hormones and in the regulation of hormone secretion
    • Garcia-Segura LM, Chowen JA, Naftolin F. Endocrine glia: roles of glial cells in the brain actions of steroid and thyroid hormones and in the regulation of hormone secretion. Front Neuroendocrinol. 1996;17:180-211.
    • (1996) Front Neuroendocrinol , vol.17 , pp. 180-211
    • Garcia-Segura, L.M.1    Chowen, J.A.2    Naftolin, F.3
  • 60
    • 0031663067 scopus 로고    scopus 로고
    • Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5′-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus
    • Diano S, Naftolin F, Goglia F, Csernus V, Horvath TL. Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5′-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus. J Neuroendocrinol. 1998;10:731-742.
    • (1998) J Neuroendocrinol , vol.10 , pp. 731-742
    • Diano, S.1    Naftolin, F.2    Goglia, F.3    Csernus, V.4    Horvath, T.L.5
  • 61
    • 0031731577 scopus 로고    scopus 로고
    • Fasting-induced increase in type II iodothyronine deiodinase activity and messenger ribonucleic acid levels is not reversed by thyroxine in the rat hypothalamus
    • Diano S, Naftolin F, Goglia F, Horvath TL. Fasting-induced increase in type II iodothyronine deiodinase activity and messenger ribonucleic acid levels is not reversed by thyroxine in the rat hypothalamus. Endocrinology. 1998;139:2879-2884.
    • (1998) Endocrinology , vol.139 , pp. 2879-2884
    • Diano, S.1    Naftolin, F.2    Goglia, F.3    Horvath, T.L.4
  • 62
    • 84862776637 scopus 로고    scopus 로고
    • Tanycytes of the hypothalamic median eminence form a diet responsive neurogenic niche
    • Lee DA, Bedont JL, Miranda-Angulo A, et al. Tanycytes of the hypothalamic median eminence form a diet responsive neurogenic niche. Nat Neurosci. 2012;15:700-702.
    • (2012) Nat Neurosci , vol.15 , pp. 700-702
    • Lee, D.A.1    Bedont, J.L.2    Miranda-Angulo, A.3
  • 63
    • 84855426656 scopus 로고    scopus 로고
    • Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice
    • McNay DEG, Briançon N, Kokoeva MV, Maratos-Flier E, Flier JS. Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice. J Clin Invest. 2012;122:142-115.
    • (2012) J Clin Invest , vol.122 , pp. 142-115
    • Deg, M.1    Briançon, N.2    Kokoeva, M.V.3    Maratos-Flier, E.4    Flier, J.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.