Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5'-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus

Journal of Neuroendocrinology

Volumn 10, Issue 10, 1998, Pages 731-742

  Diano, Sabrina ^a,b   Naftolin, Frederick ^a   Goglia, Fernando ^b   Csernus, Valer ^c   Horvath, Tamas L ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Arcuate nucleus; Astrocytes; Correlated light and electron microscopy; Deiodinase type II; Fluoro gold; In situ hybridization; Paraventricular nucleus; PHA L; Tanycytes; TRH neurons

Indexed keywords

COLCHICINE; COMPLEMENTARY RNA; FLUOROGOLD; GLIAL FIBRILLARY ACIDIC PROTEIN; LEUKOAGGLUTININ; MESSENGER RNA; PROTIRELIN; THYROTROPIN; THYROXINE DEIODINASE;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN THIRD VENTRICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EPENDYMA; FEEDBACK SYSTEM; FEMALE; HISTOCHEMISTRY; HOMEOSTASIS; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MEDIAN EMINENCE; MICROSCOPY; NERVE PROJECTION; NEUROSECRETORY CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RNA PROBE; SENSORY NERVE; SYNAPSE; THALAMUS MIDLINE NUCLEUS; THYROTROPIN RELEASE;

ANIMALS; ARCUATE NUCLEUS; FEMALE; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IODIDE PEROXIDASE; ISOENZYMES; MALE; MEDIAN EMINENCE; NEURAL PATHWAYS; NEUROGLIA; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PHYTOHEMAGGLUTININS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STILBAMIDINES; THYROTROPIN-RELEASING HORMONE;

EID: 0031663067     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2826.1998.00204.x     Document Type: Article

References (46)

1. Segerson TP, Kaucr J, Wolfe HC, Mobtaker H, Wu P, Jackson IMD, Lechan RM. Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus. Science 1987; 238: 78 80.
2. Segerson TP. Hoefler H. Childers H. Wolfe HJ, Wu P, Jackson IMD. Lechan RM. Localization of thyrotropin-releasing hormone prohormone messenger ribonucleic acid in the ral brain by in situ hybridization. Endocrinology 1987; 121: 98 107.
3. Dycss EM, Segerson TP, Liposits Zs Paull WK, Kaplan MM. Wu P, Jackson IMD, Lechan RM. Triiodothyronine exerts direct cell-specific regulation of thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus. Endocrinology 1988; 123: 2291-2297.
4. Liao N, Bulant M. Nicolas P. Vaudry H. Pelletier G. Anatomical interactions of proopiomelanocortin (POMC)-related peptides, neuropeptide Y (NPY) and dopamine β-hydroxylase (DβH) neurons in the paraventricular nucleus of rat hypothalamus, Neuropeptides 1991; 18: 63 67.
5. Toni R, Jackson IMD, Lechan RM. Neuropeptide-Y-immunoreactive innervation of thyrotropin-releasing hormone-synthesizing neurons in the rat hypothalamic paraventricular nucleus. Endocrinology 1990; 126: 2444-2453.
6. Liposits ZS, Paull WK, Wu P, Jackson IMD. Lechan RM. Hypophysiotropic thyrotropin-releasing (TRH) synthesizing neurons: ultrastructure, adrenergic innervation and putative transmitter action. Histochemistry 1987; 88: 1 9.
7. Larsen PR, Silva JE, Kaplan MM. Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications. Endoc Rev 1981; 2: 87-102.
8. Crantz FR, Silva JE, Larsen PR. An analysis of the sources and quantity of 3,5.3′-triiodothyronine specially bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology 1982; 110: 367-375.
9. Obregon MJ, Larsen PR, Silva JE. The role of 3.5.3′-triiodothyronine in the regulation of type II iodothyronine-5′-deiodinase in the rat cerebral cortex. Endocrinology 1986: 119: 2186 2192.
10. Riskind PN. Kolodny JM. Larsen PR. The regional hypothalamic distribution of type II 5′-monodeiodinase in euthyroid and hypothyroid rats. Brain Res 1987; 420: 194-198.
11. Lechan RM. Qi YP. Berrodin TJ. Davis KD. Schwartz HL, Strait KA, Oppenheimer JH. Lazar MA. Immunocytochemical delineation of thyroid hormone receptor β2-like immunoreactivity in the rat central nervous system. Endocrinology 1993; 132: 2461-2469.
12. Judd AM, Hedge GA. The role of opioid peptides in controlling thyroid stimulating hormone release. Life Sci 1982; 31: 2529 2536.
13. Mitsuma T, Hirooka Y, Nogimori T. Effects of immunoneutralization of endogenous opioid peptides on the hypothalamic-pituitary-thyroid axis in rats. Hormone Res 1993: 39: 77-80.
14. White JD. Neuropeptide Y. a central regulator of energy homeostasis. Regul Pept 1993; 49: 93-107.
15. Lechan RM, Jackson IMD. Immunohistochemical localization of thyrotropin-releasing hormone in the rat hypothalamus and pituitary. Endocrinology 1982: 111: 55-64.
16. Jackson IMD, Wu P, Lechan RM. Immunohistochemical localization in the rat brain of the precursor for thyrotropin-releasing hormone. Science 1985; 229: 1097 1099.
17. Lechan RM, Wu P, Jackson IMD. Immunolocalization of the thyrotropin-releasing hormone prohormone in the rat central nervous system. Endocrinology 1986; 119: 1210 1216.
18. Merchenthaler I, Meeker M, Petrutz P, Kizer JS. Identification and immunocytochemical localization of a new thyrotropin-releasing hormone precursor in rat brain. Endocrinology 1989; 124: 1888-1897.
19. Kawano H, Tsuruo Y, Bando H, Daikoku S. Hypophysiotrophic TRH-producing neurons identified by combining immunohistochemistry for pro-TRH and retrograde tracing. J Comp Neurol 1991; 307: 531-538.
20. Merchenthaler I, Liposits Z. Mapping of thyrotropin-releasing hormone (TRH) neuronal systems of the rat forebrain projecting to the median eminence and OVLT. Immunocytochemistry combined with retrograde labeling at the light and electron microscopic levels. Acta Biol Hung 1994; 45: 361-374.
21. Tu HM, Kim S, Salvatore D. Bartha T, Legradi G. Larsen PR, Lechan RM. Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone. Endocrinology 1997; 138: 3359-3368.
22. Zoli M. Ferraguti F, Frasoldati A, Biagini G, Agnati LF. Age-related alterations in tanycytes of the mediobasal hypothalamus of the male rat. Neurobiol Aging 1995; 16: 77-83.
23. Farwell AP, Leonard JL. Dissociation of actin polymerization and enzyme inactivation in the hormonal regulation of type II iodothyronine 5′-deiodinase activity in astrocytes. Endocrinology 1992; 131: 721 728.
24. Evans RM. The steroid and thyroid hormone receptor superfamily. Science 1988; 240: 889-895.
25. Lazar MA. Chin WW. Nuclear thyroid hormone receptors. J Clin Invest 1990; 86: 1777 1782.
26. Li M, Boyages SC. Detection of extended distribution of β2-thyroid hormone receptor messenger ribonucleic acid (RNA) in adult brain using complementary RNA in situ hybridization histochemistry. Endocrinology 1996; 137: 1272-1275.
27. Hodin RA, Lazar MA, Wintman BI. Darling DS, Koenig RJ, Larsen PR, Moore DD, Chin WW. Identification of a thyroid hormone receptor that is pituitary-specific. Science 1989; 244: 76 79.
28. Blier R. Structural relationship of ependymal cells and their processess within the the hypothalamus. In: Knigge KM. Scott DE, Weindl A. eds. Brain Endocrine Interaction. Median Eminence: Structure and Function. Basel: Karger. 1972: 306-318.
29. Bruni JE. Scanning and transmission electron microscopy of the ependymal lining of the third ventricle. J Can Sci Neurol 1974: 1: 59 73.
30. Rodriguez EM, Gonzalez CB, Delannoy L. Cellular organization of the lateral and postinfundibular regions of the median eminence in the rat. Cell Tissue Res 1979; 201: 377-408.
31. Akmayev IF, Fidelina OV. Morphological aspects of the hypothalamic hypophyseal system. VI. The tanycytes: their relation to the sexual differentiation of the hypothalamus. An enzyme-histochemical study. Cell Tissue Res 1976; 173: 407-416.
32. Serrano-Lozano A, Montiel M. Morell M, Morata P. 5′ Deiodinase activity in brain regions of adult rats: modifications in different situation of experimental hypothyroidism. Brain Res Bull 1992; 30: 611 616.
33. Harfstrand A. Brain neuropeptide Y mechanisms. Basic aspects and involvement in cardiovascular and neuroendocrine regulation. Acta Physiol Scand (Suppl) 1987; 131: 565.
34. Harfstrand A, Eneroth P, Agnati L, Fuxe K. Further studies on the effects of central administration of neuropeptide Y on neuroendocrine functioning in the male rat: relationship to hypothalamic catecholamines. Regul Pept 1987; 17: 167 179.
35. Martel JC, Pierre S. Quirion R. Neuropeptide-Y receptors in rat brain: autoradiographic localization. Peptides 1986; 7: 55.
36. Horvath TL, Bechmann I. Naftolin F, Kalra SP. Leranth C. Heterogeneity in the neuropeptide-Y-containing neurons of rat arcuate neurons: GABAergic and non-GABAergic subpopulation. Brain Rex 1997: 756: 283 286.
37. Eccles J. The Physiology of Synapses. Berlin: Springer-Verlag, 1964.
38. Croteau W, Davey JC. Galton VA. St. Germain DL. Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues. J Clin Invest 1996; 98: 405-417.
39. Sambrook J, Fritsch EF. Maniatis T. Molecular cloning. In: Nolan C. ed. New York: Cold Spring Harbor Laboratory Press, 1989.
40. Simerly RB, Chang C. Muramatsu M, Swanson LW. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neural 1990: 294: 76 95.
41. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. Orlando: Academic Press. 1986.
42. Merchenthaier I. Neurons with access to the general circulation in the central nervous system of the rat: a retrograde tracing study with fluorogold. Neuroscience 1991; 44: 655-662.
43. Merchenthaier I. The hypophysiotropic galanin system of the rat brain. Neuroscience 1991; 44: 643 654.
44. Merchenthaler I, Csernus V. Csontos C, Petrusz P, Mess B. New data on the immunocytochemical localization of thyrotropin-releasing hormone in the rat central nervous system. Am J Anat 1988: 181: 359 376.
45. Horvath TL. Suprachiasmatic efferents avoid phenestrated capillaries but innervate neuroendocrine cells including those producing dopamine. Endocrinology 1997; 138: 1312-1320.
46. Diano S, Goglia F, Naftolin F. Horvath TL. Gabaergic NPY input of parvicellular TRH cells: its origin in the arcuate nucleus and regulation by thyroid hormones. Regul Pept 1997: 71: 217.