-
1
-
-
84883180944
-
Melanoma Cell Signaling: Looking Beyond RAS-RAF-MEK
-
In, Porta, C.L., Ed.; InTech: Rijeka, Croatia
-
Muthusamy, V.; Piva, T.J. Melanoma Cell Signaling: Looking Beyond RAS-RAF-MEK. In Skin Cancers-Risk Factors, Prevention and Therapy; Porta, C.L., Ed.; InTech: Rijeka, Croatia, 2011; pp. 87-108.
-
(2011)
Skin Cancers-Risk Factors, Prevention and Therapy
, pp. 87-108
-
-
Muthusamy, V.1
Piva, T.J.2
-
2
-
-
84877590959
-
MAP kinase signaling and inhibition in melanoma
-
Sullivan, R.J.; Flaherty, K. MAP kinase signaling and inhibition in melanoma. Oncogene 2013, 32, 2373-2379.
-
(2013)
Oncogene.
, vol.32
, pp. 2373-2379
-
-
Sullivan, R.J.1
Flaherty, K.2
-
3
-
-
77955380677
-
MiTF links Erk1/2 kinase and p21CIP1/WAF1 activation after UVC radiation in normal human melanocytes and melanoma cells
-
Liu, F.; Singh, A.; Yang, Z.; Garcia, A.; Kong, Y.; Meyskens, F.L., Jr. MiTF links Erk1/2 kinase and p21CIP1/WAF1 activation after UVC radiation in normal human melanocytes and melanoma cells. Mol. Cancer 2010, 9, 214.
-
(2010)
Mol. Cancer.
, vol.9
, pp. 214
-
-
Liu, F.1
Singh, A.2
Yang, Z.3
Garcia, A.4
Kong, Y.5
Meyskens Jr., F.L.6
-
4
-
-
84866718513
-
Cell-selective inhibition of NFκB signaling improves therapeutic index in a melanoma chemotherapy model
-
Enzler, T.; Sano, Y.; Choo, M.K.; Cottam, H.B.; Karin, M.; Tsao, H.; Park, J.M. Cell-selective inhibition of NFκB signaling improves therapeutic index in a melanoma chemotherapy model. Cancer Discov. 2011, 1, 496-507.
-
(2011)
Cancer Discov.
, vol.1
, pp. 496-507
-
-
Enzler, T.1
Sano, Y.2
Choo, M.K.3
Cottam, H.B.4
Karin, M.5
Tsao, H.6
Park, J.M.7
-
5
-
-
77952559110
-
Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: Novel regulation of PUMA
-
Keuling, A.M.; Andrew, S.E.; Tron, V.A. Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: Novel regulation of PUMA. Pigment Cell Melanoma Res. 2010, 23, 430-440.
-
(2010)
Pigment Cell Melanoma Res.
, vol.23
, pp. 430-440
-
-
Keuling, A.M.1
Andrew, S.E.2
Tron, V.A.3
-
6
-
-
37549029829
-
Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2
-
Selimovic, D.; Hassan, M.; Haikel, Y.; Hengge, U.R. Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2. Cell Signal 2008, 20, 311-322.
-
(2008)
Cell Signal.
, vol.20
, pp. 311-322
-
-
Selimovic, D.1
Hassan, M.2
Haikel, Y.3
Hengge, U.R.4
-
7
-
-
77953226760
-
Activation of c-jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells
-
Shieh, J.M.; Huang, T.F.; Hung, C.F.; Chou, K.H.; Tsai, Y.J.; Wu, W.B. Activation of c-jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells. Br. J. Pharmacol. 2010, 160, 1171-1184.
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 1171-1184
-
-
Shieh, J.M.1
Huang, T.F.2
Hung, C.F.3
Chou, K.H.4
Tsai, Y.J.5
Wu, W.B.6
-
8
-
-
47249145702
-
JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis
-
Alexaki, V.I.; Javelaud, D.; Mauviel, A. JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. Pigment Cell Melanoma Res. 2008, 21, 429-438.
-
(2008)
Pigment Cell Melanoma Res.
, vol.21
, pp. 429-438
-
-
Alexaki, V.I.1
Javelaud, D.2
Mauviel, A.3
-
9
-
-
0036192304
-
An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells
-
Denkert, C.; Siegert, A.; Leclere, A.; Turzynski, A.; Hauptmann, S. An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells. Clin. Exp. Metastasis 2002, 19, 79-85.
-
(2002)
Clin. Exp. Metastasis.
, vol.19
, pp. 79-85
-
-
Denkert, C.1
Siegert, A.2
Leclere, A.3
Turzynski, A.4
Hauptmann, S.5
-
10
-
-
58649115386
-
Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation
-
Estrada, Y.; Dong, J.; Ossowski, L. Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation. Pigment Cell Melanoma Res. 2009, 22, 66-76.
-
(2009)
Pigment Cell Melanoma Res.
, vol.22
, pp. 66-76
-
-
Estrada, Y.1
Dong, J.2
Ossowski, L.3
-
11
-
-
0035953398
-
Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFα and suppression of NFκB activities
-
Ivanov, V.N.; Fodstad, O.; Ronai, Z. Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFα and suppression of NFκB activities. Oncogene 2001, 20, 2243-2253.
-
(2001)
Oncogene.
, vol.20
, pp. 2243-2253
-
-
Ivanov, V.N.1
Fodstad, O.2
Ronai, Z.3
-
12
-
-
82955162775
-
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3K/Akt signaling pathways
-
Kannaiyan, R.; Manu, K.A.; Chen, L.; Li, F.; Rajendran, P.; Subramaniam, A.; Lam, P.; Kumar, A.P.; Sethi, G. Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3K/Akt signaling pathways. Apoptosis 2011, 16, 1028-1041.
-
(2011)
Apoptosis.
, vol.16
, pp. 1028-1041
-
-
Kannaiyan, R.1
Manu, K.A.2
Chen, L.3
Li, F.4
Rajendran, P.5
Subramaniam, A.6
Lam, P.7
Kumar, A.P.8
Sethi, G.9
-
13
-
-
84872184573
-
Cyld inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways
-
Ke, H.; Augustine, C.K.; Gandham, V.D.; Jin, J.Y.; Tyler, D.S.; Akiyama, S.K.; Hall, R.P.; Zhang, J.Y. Cyld inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways. J. Investig. Dermatol. 2013, 133, 221-229.
-
(2013)
J. Investig. Dermatol.
, vol.133
, pp. 221-229
-
-
Ke, H.1
Augustine, C.K.2
Gandham, V.D.3
Jin, J.Y.4
Tyler, D.S.5
Akiyama, S.K.6
Hall, R.P.7
Zhang, J.Y.8
-
14
-
-
4444376712
-
Signaling to NFκB
-
Hayden, M.S.; Ghosh, S. Signaling to NFκB. Genes Dev. 2004, 18, 2195-2224.
-
(2004)
Genes Dev.
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
15
-
-
1842525717
-
Comparative expression of NFκB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies
-
McNulty, S.E.; del Rosario, R.; Cen, D.; Meyskens, F.L., Jr.; Yang, S. Comparative expression of NFκB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies. Pigment Cell Res. 2004, 17, 173-180.
-
(2004)
Pigment Cell Res.
, vol.17
, pp. 173-180
-
-
McNulty, S.E.1
del Rosario, R.2
Cen, D.3
Meyskens Jr., F.L.4
Yang, S.5
-
16
-
-
0035542884
-
RelA, p50 and inhibitor of κBα are elevated in human metastatic melanoma cells and respond aberrantly to ultraviolet light B
-
McNulty, S.E.; Tohidian, N.B.; Meyskens, F.L., Jr. RelA, p50 and inhibitor of κBα are elevated in human metastatic melanoma cells and respond aberrantly to ultraviolet light B. Pigment Cell Res. 2001, 14, 456-465.
-
(2001)
Pigment Cell Res.
, vol.14
, pp. 456-465
-
-
McNulty, S.E.1
Tohidian, N.B.2
Meyskens Jr., F.L.3
-
17
-
-
81555207186
-
Effect of novel marine nutraceuticals on IL-1α-mediated TNFα release from UVB-irradiated human melanocyte-derived cells
-
Muthusamy, V.; Hodges, L.D.; Macrides, T.A.; Boyle, G.M.; Piva, T.J. Effect of novel marine nutraceuticals on IL-1α-mediated TNFα release from UVB-irradiated human melanocyte-derived cells. Oxid. Med. Cell Longev. 2011, 2011, 728645.
-
(2011)
Oxid. Med. Cell Longev.
, vol.2011
, pp. 728645
-
-
Muthusamy, V.1
Hodges, L.D.2
McRides, T.A.3
Boyle, G.M.4
Piva, T.J.5
-
18
-
-
0033553421
-
Down-regulation of tumor necrosis factor α expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells
-
Ivanov, V.N.; Ronai, Z. Down-regulation of tumor necrosis factor α expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. J. Biol. Chem. 1999, 274, 14079-14089.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14079-14089
-
-
Ivanov, V.N.1
Ronai, Z.2
-
19
-
-
33846465019
-
Tumor necrosis factor-α blocks apoptosis in melanoma cells when BRAF signaling is inhibited
-
Gray-Schopfer, V.C.; Karasarides, M.; Hayward, R.; Marais, R. Tumor necrosis factor-α blocks apoptosis in melanoma cells when BRAF signaling is inhibited. Cancer Res. 2007, 67, 122-129.
-
(2007)
Cancer Res.
, vol.67
, pp. 122-129
-
-
Gray-Schopfer, V.C.1
Karasarides, M.2
Hayward, R.3
Marais, R.4
-
20
-
-
58949090367
-
Tumor vasculature-targeted delivery of tumor necrosis factor-α
-
Tandle, A.; Hanna, E.; Lorang, D.; Hajitou, A.; Moya, C.A.; Pasqualini, R.; Arap, W.; Adem, A.; Starker, E.; Hewitt, S.; et al. Tumor vasculature-targeted delivery of tumor necrosis factor-α. Cancer 2009, 115, 128-139.
-
(2009)
Cancer.
, vol.115
, pp. 128-139
-
-
Tandle, A.1
Hanna, E.2
Lorang, D.3
Hajitou, A.4
Moya, C.A.5
Pasqualini, R.6
Arap, W.7
Adem, A.8
Starker, E.9
Hewitt, S.10
-
21
-
-
0034660614
-
p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NFκB activity and Fas expression
-
Ivanov, V.N.; Ronai, Z. p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NFκB activity and Fas expression. Oncogene 2000, 19, 3003-3012.
-
(2000)
Oncogene.
, vol.19
, pp. 3003-3012
-
-
Ivanov, V.N.1
Ronai, Z.2
-
22
-
-
41049106406
-
Inflammatory doses of UV may not be necessary for skin carcinogenesis
-
Halliday, G.M.; Lyons, J.G. Inflammatory doses of UV may not be necessary for skin carcinogenesis. Photochem. Photobiol. 2008, 84, 272-283.
-
(2008)
Photochem. Photobiol.
, vol.84
, pp. 272-283
-
-
Halliday, G.M.1
Lyons, J.G.2
-
23
-
-
77549086995
-
The UV response of the skin: A review of the MAPK, NFκB and TNFα signal transduction pathways
-
Muthusamy, V.; Piva, T.J. The UV response of the skin: A review of the MAPK, NFκB and TNFα signal transduction pathways. Arch. Dermatol. Res. 2010, 302, 5-17.
-
(2010)
Arch. Dermatol. Res.
, vol.302
, pp. 5-17
-
-
Muthusamy, V.1
Piva, T.J.2
-
24
-
-
34547164540
-
The c-Jun kinase/stress-activated pathway: Regulation, function and role in human disease
-
Johnson, G.L.; Nakamura, K. The c-Jun kinase/stress-activated pathway: Regulation, function and role in human disease. Biochim. Biophys. Acta 2007, 1773, 1341-1348.
-
(2007)
Biochim. Biophys. Acta.
, vol.1773
, pp. 1341-1348
-
-
Johnson, G.L.1
Nakamura, K.2
-
25
-
-
38849199203
-
Shared principles in NFκB signaling
-
Hayden, M.S.; Ghosh, S. Shared principles in NFκB signaling. Cell 2008, 132, 344-362.
-
(2008)
Cell.
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
26
-
-
0033558614
-
Elevated constitutive IκB kinase activity and IκBα phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GROα transcription
-
Devalaraja, M.N.; Wang, D.Z.; Ballard, D.W.; Richmond, A. Elevated constitutive IκB kinase activity and IκBα phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GROα transcription. Cancer Res. 1999, 59, 1372-1377.
-
(1999)
Cancer Res.
, vol.59
, pp. 1372-1377
-
-
Devalaraja, M.N.1
Wang, D.Z.2
Ballard, D.W.3
Richmond, A.4
-
27
-
-
0035182390
-
Ultraviolet light induced injury: Immunological and inflammatory effects
-
Clydesdale, G.J.; Dandie, G.W.; Muller, H.K. Ultraviolet light induced injury: Immunological and inflammatory effects. Immunol. Cell Biol. 2001, 79, 547-568.
-
(2001)
Immunol. Cell Biol.
, vol.79
, pp. 547-568
-
-
Clydesdale, G.J.1
Dandie, G.W.2
Muller, H.K.3
-
28
-
-
0033057956
-
The effects of ultraviolet radiation on the human immune system
-
Duthie, M.S.; Kimber, I.; Norval, M. The effects of ultraviolet radiation on the human immune system. Br. J. Dermatol. 1999, 140, 995-1009.
-
(1999)
Br. J. Dermatol.
, vol.140
, pp. 995-1009
-
-
Duthie, M.S.1
Kimber, I.2
Norval, M.3
-
29
-
-
84856901018
-
The immunologic revolution: Photoimmunology
-
Ullrich, S.E.; Byrne, S.N. The immunologic revolution: Photoimmunology. J. Investig. Dermatol. 2012, 132, 896-905.
-
(2012)
J. Investig. Dermatol.
, vol.132
, pp. 896-905
-
-
Ullrich, S.E.1
Byrne, S.N.2
-
30
-
-
63149123561
-
UVB and proinflammatory cytokines synergistically activate TNFα production in keratinocytes through enhanced gene transcription
-
Bashir, M.M.; Sharma, M.R.; Werth, V.P. UVB and proinflammatory cytokines synergistically activate TNFα production in keratinocytes through enhanced gene transcription. J. Investig. Dermatol. 2009, 129, 994-1001.
-
(2009)
J. Investig. Dermatol.
, vol.129
, pp. 994-1001
-
-
Bashir, M.M.1
Sharma, M.R.2
Werth, V.P.3
-
31
-
-
0031896910
-
Anisomycin selectively desensitizes signaling components involved in stress kinase activation and fos and jun induction
-
Hazzalin, C.A.; Le Panse, R.; Cano, E.; Mahadevan, L.C. Anisomycin selectively desensitizes signaling components involved in stress kinase activation and fos and jun induction. Mol. Cell Biol. 1998, 18, 1844-1854.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1844-1854
-
-
Hazzalin, C.A.1
le Panse, R.2
Cano, E.3
Mahadevan, L.C.4
-
32
-
-
34248630805
-
Confirmation of a BRAF mutation-associated gene expression signature in melanoma
-
Johansson, P.; Pavey, S.; Hayward, N. Confirmation of a BRAF mutation-associated gene expression signature in melanoma. Pigment Cell Res. 2007, 20, 216-221.
-
(2007)
Pigment Cell Res.
, vol.20
, pp. 216-221
-
-
Johansson, P.1
Pavey, S.2
Hayward, N.3
-
33
-
-
0030728259
-
CDKN2A/p16 is inactivated in most melanoma cell lines
-
Castellano, M.; Pollock, P.M.; Walters, M.K.; Sparrow, L.E.; Down, L.M.; Gabrielli, B.G.; Parsons, P.G.; Hayward, N.K. CDKN2A/p16 is inactivated in most melanoma cell lines. Cancer Res. 1997, 57, 4868-4875.
-
(1997)
Cancer Res.
, vol.57
, pp. 4868-4875
-
-
Castellano, M.1
Pollock, P.M.2
Walters, M.K.3
Sparrow, L.E.4
Down, L.M.5
Gabrielli, B.G.6
Parsons, P.G.7
Hayward, N.K.8
-
34
-
-
0018764384
-
Regius Mary Sister. Human malignant melanoma cell lines
-
Pope, J.H.; Morrison, L.; Moss, D.J.; Parsons, P.G.; Regius Mary Sister. Human malignant melanoma cell lines. Pathology 1979, 11, 191-195.
-
(1979)
Pathology
, vol.11
, pp. 191-195
-
-
Pope, J.H.1
Morrison, L.2
Moss, D.J.3
Parsons, P.G.4
-
35
-
-
0041835985
-
Cutaneous photobiology. The melanocyte vs. the sun: Who will win the final round?
-
Kadekaro, A.L.; Kavanagh, R.J.; Wakamatsu, K.; Ito, S.; Pipitone, M.A.; Abdel-Malek, Z.A. Cutaneous photobiology. The melanocyte vs. the sun: Who will win the final round? Pigment Cell Res. 2003, 16, 434-447.
-
(2003)
Pigment Cell Res.
, vol.16
, pp. 434-447
-
-
Kadekaro, A.L.1
Kavanagh, R.J.2
Wakamatsu, K.3
Ito, S.4
Pipitone, M.A.5
Abdel-Malek, Z.A.6
-
36
-
-
0018661945
-
Photoprotection by melanin-A comparison of black and caucasian skin
-
Kaidbey, K.H.; Agin, P.P.; Sayre, R.M.; Kligman, A.M. Photoprotection by melanin-A comparison of black and caucasian skin. J. Am. Acad. Dermatol. 1979, 1, 249-260.
-
(1979)
J. Am. Acad. Dermatol.
, vol.1
, pp. 249-260
-
-
Kaidbey, K.H.1
Agin, P.P.2
Sayre, R.M.3
Kligman, A.M.4
-
37
-
-
0031954130
-
Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis
-
Kobayashi, N.; Nakagawa, A.; Muramatsu, T.; Yamashina, Y.; Shirai, T.; Hashimoto, M.W.; Ishigaki, Y.; Ohnishi, T.; Mori, T. Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis. J. Investig. Dermatol. 1998, 110, 806-810.
-
(1998)
J. Investig. Dermatol.
, vol.110
, pp. 806-810
-
-
Kobayashi, N.1
Nakagawa, A.2
Muramatsu, T.3
Yamashina, Y.4
Shirai, T.5
Hashimoto, M.W.6
Ishigaki, Y.7
Ohnishi, T.8
Mori, T.9
-
38
-
-
0025826887
-
Disparate antioxidant enzyme activities in cultured human cutaneous fibroblasts, keratinocytes, and melanocytes
-
Yohn, J.J.; Norris, D.A.; Yrastorza, D.G.; Buno, I.J.; Leff, J.A.; Hake, S.S.; Repine, J.E. Disparate antioxidant enzyme activities in cultured human cutaneous fibroblasts, keratinocytes, and melanocytes. J. Investig. Dermatol. 1991, 97, 405-409.
-
(1991)
J. Investig. Dermatol.
, vol.97
, pp. 405-409
-
-
Yohn, J.J.1
Norris, D.A.2
Yrastorza, D.G.3
Buno, I.J.4
Leff, J.A.5
Hake, S.S.6
Repine, J.E.7
-
39
-
-
2142657814
-
Functional genomics of UV radiation responses in human cells
-
Koch-Paiz, C.A.; Amundson, S.A.; Bittner, M.L.; Meltzer, P.S.; Fornace, A.J., Jr. Functional genomics of UV radiation responses in human cells. Mutat. Res. 2004, 549, 65-78.
-
(2004)
Mutat. Res.
, vol.549
, pp. 65-78
-
-
Koch-Paiz, C.A.1
Amundson, S.A.2
Bittner, M.L.3
Meltzer, P.S.4
Fornace Jr., A.J.5
-
40
-
-
46749087013
-
Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells
-
Besaratinia, A.; Kim, S.I.; Pfeifer, G.P. Rapid repair of UVA-induced oxidized purines and persistence of UVB-induced dipyrimidine lesions determine the mutagenicity of sunlight in mouse cells. FASEB J. 2008, 22, 2379-2392.
-
(2008)
FASEB J.
, vol.22
, pp. 2379-2392
-
-
Besaratinia, A.1
Kim, S.I.2
Pfeifer, G.P.3
-
41
-
-
16844372768
-
Molecular crosstalk of the ultraviolet A and ultraviolet B signaling responses at the level of mitogen-activated protein kinases
-
Schieke, S.M.; Ruwiedel, K.; Gers-Barlag, H.; Grether-Beck, S.; Krutmann, J. Molecular crosstalk of the ultraviolet A and ultraviolet B signaling responses at the level of mitogen-activated protein kinases. J. Investig. Dermatol. 2005, 124, 857-859.
-
(2005)
J. Investig. Dermatol.
, vol.124
, pp. 857-859
-
-
Schieke, S.M.1
Ruwiedel, K.2
Gers-Barlag, H.3
Grether-Beck, S.4
Krutmann, J.5
-
42
-
-
17144371848
-
Jnk2: A negative regulator of cellular proliferation
-
Sabapathy, K.; Wagner, E.F. Jnk2: A negative regulator of cellular proliferation. Cell Cycle 2004, 3, 1520-1523.
-
(2004)
Cell Cycle.
, vol.3
, pp. 1520-1523
-
-
Sabapathy, K.1
Wagner, E.F.2
-
43
-
-
0035872409
-
Suppression of skin tumorigenesis in c-Jun NH2-terminal kinase-2-deficient mice
-
Chen, N.; Nomura, M.; She, Q.B.; Ma, W.Y.; Bode, A.M.; Wang, L.; Flavell, R.A.; Dong, Z. Suppression of skin tumorigenesis in c-Jun NH2-terminal kinase-2-deficient mice. Cancer Res. 2001, 61, 3908-3912.
-
(2001)
Cancer Res.
, vol.61
, pp. 3908-3912
-
-
Chen, N.1
Nomura, M.2
She, Q.B.3
Ma, W.Y.4
Bode, A.M.5
Wang, L.6
Flavell, R.A.7
Dong, Z.8
-
44
-
-
34147131695
-
JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response
-
Tao, J.; Gao, Y.; Li, M.O.; He, W.; Chen, L.; Harvev, B.; Davis, R.J.; Flavell, R.A.; Yin, Z. JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response. Eur. J. Immunol. 2007, 37, 818-829.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 818-829
-
-
Tao, J.1
Gao, Y.2
Li, M.O.3
He, W.4
Chen, L.5
Harvev, B.6
Davis, R.J.7
Flavell, R.A.8
Yin, Z.9
-
45
-
-
0346963109
-
Detection of mutations in the mitogen-activated protein kinase pathway in human melanoma
-
Alsina, J.; Gorsk, D.H.; Germino, F.J.; Shih, W.; Lu, S.E.; Zhang, Z.G.; Yang, J.M.; Hait, W.N.; Goydos, J.S. Detection of mutations in the mitogen-activated protein kinase pathway in human melanoma. Clin. Cancer Res. 2003, 9, 6419-6425.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 6419-6425
-
-
Alsina, J.1
Gorsk, D.H.2
Germino, F.J.3
Shih, W.4
Lu, S.E.5
Zhang, Z.G.6
Yang, J.M.7
Hait, W.N.8
Goydos, J.S.9
-
46
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
-
Hoshino, R.; Chatani, Y.; Yamori, T.; Tsuruo, T.; Oka, H.; Yoshida, O.; Shimada, Y.; Ari-i, S.; Wada, H.; Fujimoto, J.; et al. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 1999, 18, 813-822.
-
(1999)
Oncogene.
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
Shimada, Y.7
Ari-i, S.8
Wada, H.9
Fujimoto, J.10
-
47
-
-
0141508024
-
Treatment of metastatic melanoma with an orally available inhibitor of the Ras-Raf-MAPK cascade
-
Collisson, E.A.; de, A.; Suzuki, H.; Gambhir, S.S.; Kolodney, M.S. Treatment of metastatic melanoma with an orally available inhibitor of the Ras-Raf-MAPK cascade. Cancer Res. 2003, 63, 5669-5673.
-
(2003)
Cancer Res.
, vol.63
, pp. 5669-5673
-
-
Collisson, E.A.1
de, A.2
Suzuki, H.3
Gambhir, S.S.4
Kolodney, M.S.5
-
48
-
-
2942533921
-
Microarray expression profiling in melanoma reveals a BRAF mutation signature
-
Pavey, S.; Johansson, P.; Packer, L.; Taylor, J.; Stark, M.; Pollock, P.M.; Walker, G.J.; Boyle, G.M.; Harper, U.; Cozzi, S.J.; et al. Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene 2004, 23, 4060-4067.
-
(2004)
Oncogene.
, vol.23
, pp. 4060-4067
-
-
Pavey, S.1
Johansson, P.2
Packer, L.3
Taylor, J.4
Stark, M.5
Pollock, P.M.6
Walker, G.J.7
Boyle, G.M.8
Harper, U.9
Cozzi, S.J.10
-
49
-
-
34247606483
-
Rewired ERK-JNK signaling pathways in melanoma
-
Lopez-Bergami, P.; Huang, C.; Goydos, J.S.; Yip, D.; Bar-Eli, M.; Herlyn, M.; Smalley, K.S.; Mahale, A.; Eroshkin, A.; Aaronson, S.; et al. Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell 2007, 11, 447-460.
-
(2007)
Cancer Cell.
, vol.11
, pp. 447-460
-
-
Lopez-Bergami, P.1
Huang, C.2
Goydos, J.S.3
Yip, D.4
Bar-Eli, M.5
Herlyn, M.6
Smalley, K.S.7
Mahale, A.8
Eroshkin, A.9
Aaronson, S.10
-
50
-
-
0036381474
-
Effects of UVA and L-ascorbic acid on nuclear factor-κB in melanocytes and in HaCaT keratinocytes
-
Shang, J.; Schwarz, C.; Sanchez Ruderisch, H.; Hertting, T.; Orfanos, C.E.; Tebbe, B. Effects of UVA and L-ascorbic acid on nuclear factor-κB in melanocytes and in HaCaT keratinocytes. Skin Pharmacol. Appl. Skin Physiol. 2002, 15, 353-359.
-
(2002)
Skin Pharmacol. Appl. Skin Physiol.
, vol.15
, pp. 353-359
-
-
Shang, J.1
Schwarz, C.2
Sanchez Ruderisch, H.3
Hertting, T.4
Orfanos, C.E.5
Tebbe, B.6
-
51
-
-
0033559688
-
UVA-induced decrease in nuclear factor-κB activity in human keratinocytes
-
Djavaheri-Mergny, M.; Gras, M.P.; Mergny, J.L.; Dubertret, L. UVA-induced decrease in nuclear factor-κB activity in human keratinocytes. Biochem. J. 1999, 338, 607-613.
-
(1999)
Biochem. J.
, vol.338
, pp. 607-613
-
-
Djavaheri-Mergny, M.1
Gras, M.P.2
Mergny, J.L.3
Dubertret, L.4
-
52
-
-
0031725533
-
Dose-dependent induction of IL-12 but not IL-10 from human keratinocytes after exposure to ultraviolet light a
-
Kondo, S.; Jimbow, K. Dose-dependent induction of IL-12 but not IL-10 from human keratinocytes after exposure to ultraviolet light a. J. Cell Physiol. 1998, 177, 493-498.
-
(1998)
J. Cell Physiol.
, vol.177
, pp. 493-498
-
-
Kondo, S.1
Jimbow, K.2
-
53
-
-
0037293541
-
NF-κB-mediated induction of p21(cip1/waf1) by tumor necrosis factor α induces growth arrest and cytoprotection in normal human keratinocytes
-
Basile, J.R.; Eichten, A.; Zacny, V.; Munger, K. NF-κB-mediated induction of p21(cip1/waf1) by tumor necrosis factor α induces growth arrest and cytoprotection in normal human keratinocytes. Mol. Cancer Res. 2003, 1, 262-270.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 262-270
-
-
Basile, J.R.1
Eichten, A.2
Zacny, V.3
Munger, K.4
-
54
-
-
58149487765
-
TNFα-induced activation of NFκB protects against UV-induced apoptosis specifically in p53-proficient cells
-
Szoltysek, K.; Pietranek, K.; Kalinowska-Herok, M.; Pietrowska, M.; Kimmel, M.; Widlak, P. TNFα-induced activation of NFκB protects against UV-induced apoptosis specifically in p53-proficient cells. Acta Biochim. Pol. 2008, 55, 741-748.
-
(2008)
Acta Biochim. Pol.
, vol.55
, pp. 741-748
-
-
Szoltysek, K.1
Pietranek, K.2
Kalinowska-Herok, M.3
Pietrowska, M.4
Kimmel, M.5
Widlak, P.6
-
55
-
-
38649116610
-
Caffeine inhibits UV-mediated NFκB activation in A2058 melanoma cells: An ATM-PKCδ-p38 MAPK-dependent mechanism
-
Ravi, D.; Muniyappa, H.; Das, K.C. Caffeine inhibits UV-mediated NFκB activation in A2058 melanoma cells: An ATM-PKCδ-p38 MAPK-dependent mechanism. Mol. Cell Biochem. 2008, 308, 193-200.
-
(2008)
Mol. Cell Biochem.
, vol.308
, pp. 193-200
-
-
Ravi, D.1
Muniyappa, H.2
Das, K.C.3
-
56
-
-
34648814154
-
p38 MAPK in regulating cellular responses to ultraviolet radiation
-
Jinlian, L.; Yingbin, Z.; Chunbo, W. p38 MAPK in regulating cellular responses to ultraviolet radiation. J. Biomed. Sci. 2007, 14, 303-312.
-
(2007)
J. Biomed. Sci.
, vol.14
, pp. 303-312
-
-
Jinlian, L.1
Yingbin, Z.2
Chunbo, W.3
-
58
-
-
58349113170
-
Effect of 308 nm excimer laser irradiation on retinal pigment epithelium cell viability in vitro
-
Krohne, T.U.; Hunt, S.; Holz, F.G. Effect of 308 nm excimer laser irradiation on retinal pigment epithelium cell viability in vitro. Br. J. Ophthalmol. 2009, 93, 91-95.
-
(2009)
Br. J. Ophthalmol.
, vol.93
, pp. 91-95
-
-
Krohne, T.U.1
Hunt, S.2
Holz, F.G.3
-
59
-
-
65749113341
-
The protective effects of ultraviolet A1 irradiation on spontaneous lupus erythematosus-like skin lesions in MRL/lpr mice
-
Mikita, N.; Kanazawa, N.; Yoshimasu, T.; Ikeda, T.; Li, H.J.; Yamamoto, Y.; Furukawa, F. The protective effects of ultraviolet A1 irradiation on spontaneous lupus erythematosus-like skin lesions in MRL/lpr mice. Clin. Dev. Immunol. 2009, 2009, 673952.
-
(2009)
Clin. Dev. Immunol.
, vol.2009
, pp. 673952
-
-
Mikita, N.1
Kanazawa, N.2
Yoshimasu, T.3
Ikeda, T.4
Li, H.J.5
Yamamoto, Y.6
Furukawa, F.7
-
60
-
-
0036277752
-
Ultraviolet A augments solar-simulated ultraviolet radiation-induced local suppression of recall responses in humans
-
Kuchel, J.M.; Barnetson, R.S.; Halliday, G.M. Ultraviolet A augments solar-simulated ultraviolet radiation-induced local suppression of recall responses in humans. J. Investig. Dermatol. 2002, 118, 1032-1037.
-
(2002)
J. Investig. Dermatol.
, vol.118
, pp. 1032-1037
-
-
Kuchel, J.M.1
Barnetson, R.S.2
Halliday, G.M.3
-
61
-
-
58149522579
-
Effect of ultraviolet radiation on the expression of pp38MAPK and furin in human keratinocyte-derived cell lines
-
Huynh, T.T.; Chan, K.S.; Piva, T.J. Effect of ultraviolet radiation on the expression of pp38MAPK and furin in human keratinocyte-derived cell lines. Photodermatol. Photoimmunol. Photomed. 2009, 25, 20-29.
-
(2009)
Photodermatol. Photoimmunol. Photomed.
, vol.25
, pp. 20-29
-
-
Huynh, T.T.1
Chan, K.S.2
Piva, T.J.3
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