메뉴 건너뛰기




Volumn 133, Issue 1, 2013, Pages 221-229

CYLD inhibits melanoma growth and progression through suppression of the jnk/ap-1 and β1-integrin signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; COLLAGEN TYPE 4; CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; NERVE CELL ADHESION MOLECULE; PROTEIN BCL 3; PROTEIN CYLD; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84872184573     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.253     Document Type: Article
Times cited : (48)

References (41)
  • 1
    • 47249145702 scopus 로고    scopus 로고
    • JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis
    • Alexaki VI, Javelaud D, Mauviel A (2008) JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. Pigment Cell Melanoma Res 21:429-388
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 429-388
    • Alexaki, V.I.1    Javelaud, D.2    Mauviel, A.3
  • 2
    • 77954959943 scopus 로고    scopus 로고
    • Immunotherapy for melanoma: Current status and perspectives
    • Alexandrescu DT, Ichim TE, Riordan NH et al. (2010) Immunotherapy for melanoma: Current status and perspectives. J Immunother 33:570-900
    • (2010) J Immunother , vol.33 , pp. 570-900
    • Alexandrescu, D.T.1    Ichim, T.E.2    Riordan, N.H.3
  • 3
    • 18844464056 scopus 로고    scopus 로고
    • Identification of the familial cylindromatosis tumour-suppressor gene
    • Bignell GR, Warren W, Seal S et al. (2000) Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet 25:160-55
    • (2000) Nat Genet , vol.25 , pp. 160-165
    • Bignell, G.R.1    Warren, W.2    Seal, S.3
  • 4
    • 0042467554 scopus 로고    scopus 로고
    • Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NFkappaB
    • Brummelkamp TR, Nijman SM, Dirac AM et al. (2003) Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NFkappaB. Nature 424:797-8011
    • (2003) Nature , vol.424 , pp. 797-8011
    • Brummelkamp, T.R.1    Nijman, S.M.2    Dirac, A.M.3
  • 5
    • 0025362679 scopus 로고
    • Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies
    • Fogerty FJ, Akiyama SK, Yamada KM et al. (1990) Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies. J Cell Biol 111:699-7088
    • (1990) J Cell Biol , vol.111 , pp. 699-7088
    • Fogerty, F.J.1    Akiyama, S.K.2    Yamada, K.M.3
  • 6
    • 33847220364 scopus 로고    scopus 로고
    • Melanoma biology and new targeted therapy
    • Gray-Schopfer V, Wellbrock C, Marais R (2007) Melanoma biology and new targeted therapy. Nature 445:851-77
    • (2007) Nature , vol.445 , pp. 851-877
    • Gray-Schopfer, V.1    Wellbrock, C.2    Marais, R.3
  • 7
    • 0036532136 scopus 로고    scopus 로고
    • Collective cell movement in primary melanoma explants: Plasticity of cell-cell interaction, beta1- integrin function, and migration strategies
    • Hegerfeldt Y, Tusch M, Brocker EB et al. (2002) Collective cell movement in primary melanoma explants: Plasticity of cell-cell interaction, beta1- integrin function, and migration strategies. Cancer Res 62:2125-21300
    • (2002) Cancer Res , vol.62 , pp. 2125-21300
    • Hegerfeldt, Y.1    Tusch, M.2    Brocker, E.B.3
  • 8
    • 33845679104 scopus 로고    scopus 로고
    • Reduced expression of CYLD in human colon and hepatocellular carcinomas
    • Hellerbrand C, Bumes E, Bataille F et al. (2007) Reduced expression of CYLD in human colon and hepatocellular carcinomas. Carcinogenesis 28:21-77
    • (2007) Carcinogenesis , vol.28 , pp. 21-77
    • Hellerbrand, C.1    Bumes, E.2    Bataille, F.3
  • 9
    • 1842852605 scopus 로고    scopus 로고
    • Conventional and arraybased comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix
    • Hirai Y, Kawamata Y, Takeshima N et al. (2004) Conventional and arraybased comparative genomic hybridization analyses of novel cell lines harboring HPV18 from glassy cell carcinoma of the uterine cervix. Int J Oncol 24:977-866
    • (2004) Int J Oncol , vol.24 , pp. 977-866
    • Hirai, Y.1    Kawamata, Y.2    Takeshima, N.3
  • 10
    • 0034811438 scopus 로고    scopus 로고
    • Ca2+ i as a potential downregulator of alpha2beta1-integrin-mediated A2058 tumor cell migration to type IV collagen
    • Hodgson L, Dong C (2001) [Ca2+]i as a potential downregulator of alpha2beta1-integrin-mediated A2058 tumor cell migration to type IV collagen. Am J Physiol Cell Physiol 281:C106-133
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Hodgson, L.1    Dong, C.2
  • 11
    • 0037294644 scopus 로고    scopus 로고
    • Retinoic acid-induced AP-11 transcriptional activity regulates B16 mouse melanoma growth inhibition and differentiation
    • Huang Y, Boskovic G, Niles RM (2003) Retinoic acid-induced AP-11 transcriptional activity regulates B16 mouse melanoma growth inhibition and differentiation. J Cell Physiol 194:162-700
    • (2003) J Cell Physiol , vol.194 , pp. 162-700
    • Huang, Y.1    Boskovic, G.2    Niles, R.M.3
  • 12
    • 65649114699 scopus 로고    scopus 로고
    • Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation
    • Hutti JE, Shen RR, Abbott DW et al. (2009) Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Mol Cell 34:461-722
    • (2009) Mol Cell , vol.34 , pp. 461-722
    • Hutti, J.E.1    Shen, R.R.2    Abbott, D.W.3
  • 13
    • 36148955443 scopus 로고    scopus 로고
    • Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma
    • Jenner MW, Leone PE, Walker BA et al. (2007) Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma. Blood 110:3291-3000
    • (2007) Blood , vol.110 , pp. 3291-3000
    • Jenner, M.W.1    Leone, P.E.2    Walker, B.A.3
  • 14
    • 79954718554 scopus 로고    scopus 로고
    • 011 c-Jun promotes whereas JunB inhibits epidermal neoplasia
    • Jin JY, Ke H, Hall RP et al. (2011) c-Jun promotes whereas JunB inhibits epidermal neoplasia. J Invest Dermatol 131:1149-588
    • J Invest Dermatol , vol.131 , pp. 1149-1588
    • Jin, J.Y.1    Ke, H.2    Hall, R.P.3
  • 15
    • 80053549222 scopus 로고    scopus 로고
    • Integrin targeted delivery of gene therapeutics
    • Juliano RL, Ming X, Nakagawa O et al. (2011) Integrin targeted delivery of gene therapeutics. Theranostics 1:211-99
    • (2011) Theranostics , vol.1 , pp. 211-299
    • Juliano, R.L.1    Ming, X.2    Nakagawa, O.3
  • 16
    • 77951037489 scopus 로고    scopus 로고
    • The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia
    • Ke H, Harris R, Coloff JL et al. (2010) The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia. Cancer Res 70:3080-88
    • (2010) Cancer Res , vol.70 , pp. 3080-3088
    • Ke, H.1    Harris, R.2    Coloff, J.L.3
  • 17
    • 46049103996 scopus 로고    scopus 로고
    • Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
    • Kikuno N, Shiina H, Urakami S et al. (2008) Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. Int J Cancer 123:552-600
    • (2008) Int J Cancer , vol.123 , pp. 552-600
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3
  • 18
    • 0041967054 scopus 로고    scopus 로고
    • The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
    • Kovalenko A, Chable-Bessia C, Cantarella G et al. (2003) The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 424:801-55
    • (2003) Nature , vol.424 , pp. 801-855
    • Kovalenko, A.1    Chable-Bessia, C.2    Cantarella, G.3
  • 19
    • 67449150231 scopus 로고    scopus 로고
    • Increasing burden of melanoma in the United States
    • Linos E, Swetter SM, Cockburn MG et al. (2009) Increasing burden of melanoma in the United States. J Invest Dermatol 129:1666-744
    • (2009) J Invest Dermatol , vol.129 , pp. 1666-1744
    • Linos, E.1    Swetter, S.M.2    Cockburn, M.G.3
  • 20
    • 34247606483 scopus 로고    scopus 로고
    • Rewired ERK-JNK signaling pathways in melanoma
    • Lopez-Bergami P, Huang C, Goydos JS et al. (2007) Rewired ERK-JNK signaling pathways in melanoma. Cancer Cell 11:447-600
    • (2007) Cancer Cell , vol.11 , pp. 447-600
    • Lopez-Bergami, P.1    Huang, C.2    Goydos, J.S.3
  • 21
    • 79952152655 scopus 로고    scopus 로고
    • CYLD: A deubiquitination enzyme with multiple roles in cancer
    • Massoumi R (2011) CYLD: A deubiquitination enzyme with multiple roles in cancer. Future Oncol 7:285-977
    • (2011) Future Oncol , vol.7 , pp. 285-977
    • Massoumi, R.1
  • 22
    • 33646531810 scopus 로고    scopus 로고
    • Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling
    • Massoumi R, Chmielarska K, Hennecke K et al. (2006) Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. Cell 125:665-777
    • (2006) Cell , vol.125 , pp. 665-777
    • Massoumi, R.1    Chmielarska, K.2    Hennecke, K.3
  • 23
    • 60549102324 scopus 로고    scopus 로고
    • Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma
    • Massoumi R, Kuphal S, Hellerbrand C et al. (2009) Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med 206:221-322
    • (2009) J Exp Med , vol.206 , pp. 221-322
    • Massoumi, R.1    Kuphal, S.2    Hellerbrand, C.3
  • 24
    • 79957845596 scopus 로고    scopus 로고
    • CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels
    • Miliani de Marval P, Lutfeali S, Jin JY et al. (2011) CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels. Cancer Prev Res (Phila) 4:851-99
    • (2011) Cancer Prev Res (Phila , Issue.4 , pp. 851-899
    • Miliani De Marval, P.1    Lutfeali, S.2    Jin, J.Y.3
  • 25
    • 0028944308 scopus 로고
    • Identification of a novel antiintegrin monoclonal antibody that recognises a ligand-induced binding site epitope on the beta 1 subunit
    • Mould AP, Garratt AN, Askari JA et al. (1995) Identification of a novel antiintegrin monoclonal antibody that recognises a ligand-induced binding site epitope on the beta 1 subunit. FEBS Lett 363:118-222
    • (1995) FEBS Lett , vol.363 , pp. 118-222
    • Mould, A.P.1    Garratt, A.N.2    Askari, J.A.3
  • 26
    • 0033201447 scopus 로고    scopus 로고
    • Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation
    • Na SY, Choi JE, Kim HJ et al. (1999) Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation. J Biol Chem 274:28491-66
    • (1999) J Biol Chem , vol.274 , pp. 28491-28476
    • Na, S.Y.1    Choi, J.E.2    Kim, H.J.3
  • 27
    • 0029965589 scopus 로고    scopus 로고
    • A mechanism for regulation of melanoma invasion. Ligation of alpha6beta1 integrin by laminin G peptides
    • Nakahara H, Nomizu M, Akiyama SK et al. (1996) A mechanism for regulation of melanoma invasion. Ligation of alpha6beta1 integrin by laminin G peptides. J Biol Chem 271:27221-44
    • (1996) J Biol Chem , vol.271 , pp. 27221-27244
    • Nakahara, H.1    Nomizu, M.2    Akiyama, S.K.3
  • 28
    • 79952613582 scopus 로고    scopus 로고
    • Integrins: Versatile receptors controlling melanocyte adhesion, migration and proliferation
    • Pinon P, Wehrle-Haller B (2010) Integrins: Versatile receptors controlling melanocyte adhesion, migration and proliferation. Pigment Cell Melanoma Res 24:282-944
    • (2010) Pigment Cell Melanoma Res , vol.24 , pp. 282-944
    • Pinon, P.1    Wehrle-Haller, B.2
  • 29
    • 0346333095 scopus 로고    scopus 로고
    • The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor
    • Regamey A, Hohl D, Liu JW et al. (2003) The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. J Exp Med 198:1959-644
    • (2003) J Exp Med , vol.198 , pp. 1959-1654
    • Regamey, A.1    Hohl, D.2    Liu, J.W.3
  • 30
    • 11244341060 scopus 로고    scopus 로고
    • Negative regulation of JNK signaling by the tumor suppressor CYLD
    • Reiley W, Zhang M, Sun SC (2004) Negative regulation of JNK signaling by the tumor suppressor CYLD. J Biol Chem 279:55161-77
    • (2004) J Biol Chem , vol.279 , pp. 55161-55177
    • Reiley, W.1    Zhang, M.2    Sun, S.C.3
  • 31
    • 34250368115 scopus 로고    scopus 로고
    • Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses
    • Reiley WW, Jin W, Lee AJ et al. (2007) Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. J Exp Med 204:1475-855
    • (2007) J Exp Med , vol.204 , pp. 1475-1855
    • Reiley, W.W.1    Jin, W.2    Lee, A.J.3
  • 32
    • 33645103440 scopus 로고    scopus 로고
    • Regulation of T cell development by the deubiquitinating enzyme CYLD
    • Reiley WW, Zhang M, JinWet al. (2006) Regulation of T cell development by the deubiquitinating enzyme CYLD. Nat Immunol 7:411-77
    • (2006) Nat Immunol , vol.7 , pp. 411-477
    • Reiley, W.W.1    Zhang, M.2    Jin, W.3
  • 33
    • 34547421345 scopus 로고    scopus 로고
    • The tumor suppressor CYLD regulates entry into mitosis
    • Stegmeier F, Sowa ME, Nalepa G et al. (2007) The tumor suppressor CYLD regulates entry into mitosis. Proc Natl Acad Sci USA 104: 8869-744
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8869-8754
    • Stegmeier, F.1    Sowa, M.E.2    Nalepa, G.3
  • 34
    • 0036139131 scopus 로고    scopus 로고
    • Spiradenocylindroma of the kidney: Clinical and genetic findings suggesting a role of somatic mutation of the CYLD1 gene in the oncogenesis of an unusual renal neoplasm
    • Strobel P, Zettl A, Ren Z et al. (2002) Spiradenocylindroma of the kidney: Clinical and genetic findings suggesting a role of somatic mutation of the CYLD1 gene in the oncogenesis of an unusual renal neoplasm. Am J Surg Pathol 26:119-244
    • (2002) Am J Surg Pathol , vol.26 , pp. 119-244
    • Strobel, P.1    Zettl, A.2    Ren, Z.3
  • 35
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
    • Trompouki E, Hatzivassiliou E, Tsichritzis T et al. (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 424:793-66
    • (2003) Nature , vol.424 , pp. 793-776
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3
  • 36
    • 33644841576 scopus 로고    scopus 로고
    • NF-kappaB activation in melanoma
    • Ueda Y, Richmond A (2006) NF-kappaB activation in melanoma. Pigment Cell Res 19:112-244
    • (2006) Pigment Cell Res , vol.19 , pp. 112-244
    • Ueda, Y.1    Richmond, A.2
  • 37
    • 24344465793 scopus 로고    scopus 로고
    • The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene
    • Wang L, Baiocchi RA, Pal S et al. (2005) The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene. Mol Cell Biol 25:7953-655
    • (2005) Mol Cell Biol , vol.25 , pp. 7953-7665
    • Wang, L.1    Baiocchi, R.A.2    Pal, S.3
  • 38
    • 0030660073 scopus 로고    scopus 로고
    • Regulation of ubiquitin-dependent processes by deubiquitinating enzymes
    • Wilkinson KD (1997) Regulation of ubiquitin-dependent processes by deubiquitinating enzymes. FASEB J 11:1245-566
    • (1997) FASEB J , vol.11 , pp. 1245-1566
    • Wilkinson, K.D.1
  • 39
    • 0842348917 scopus 로고    scopus 로고
    • During human melanoma progression AP-1 binding pairs are altered with loss of c-Jun in vitro
    • Yang S, McNulty S, Meyskens Jr FL (2004) During human melanoma progression AP-1 binding pairs are altered with loss of c-Jun in vitro. Pigment Cell Res 17:74-833
    • (2004) Pigment Cell Res , vol.17 , pp. 74-833
    • Yang, S.1    McNulty, S.2    Meyskens Jr., F.L.3
  • 40
    • 34248582787 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor 1//c-Jun-NH2-kinase signaling promotes human neoplasia
    • Zhang JY, Adams AE, Ridky TW et al. (2007) Tumor necrosis factor receptor 1//c-Jun-NH2-kinase signaling promotes human neoplasia. Cancer Res 67:3827-344
    • (2007) Cancer Res , vol.67 , pp. 3827-3354
    • Zhang, J.Y.1    Adams, A.E.2    Ridky, T.W.3
  • 41
    • 0033158929 scopus 로고    scopus 로고
    • Expression of the alpha7beta11 laminin receptor suppresses melanoma growth and metastatic potential
    • Ziober BL, Chen YQ, Ramos DM et al. (1999) Expression of the alpha7beta11 laminin receptor suppresses melanoma growth and metastatic potential. Cell Growth Differ 10:479-900
    • (1999) Cell Growth Differ , vol.10 , pp. 479-900
    • Ziober, B.L.1    Chen, Y.Q.2    Ramos, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.