Caffeine inhibits UV-mediated NF-κB activation in A2058 melanoma cells: An ATM-PKCδ-p38 MAPK-dependent mechanism

Molecular and Cellular Biochemistry

Volumn 308, Issue 1-2, 2008, Pages 193-200

  Ravi, Dashnamoorthy ^a   Muniyappa, Harish ^a   Das, Kumuda C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

A2058; ATM; Caffeine; Ku55399; Melanoma cells; p38MAPK; PIKK; Proteinkinase C; TNFa; UV

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ATM PROTEIN; CAFFEINE; CALPHOSTIN C; CHECKPOINT KINASE RAD3; DNA DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C DELTA; ROTTLERIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MELANOMA CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION;

CAFFEINE; CASEIN KINASE II; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; I-KAPPA B PROTEINS; MELANOMA; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C-DELTA; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS; ULTRAVIOLET RAYS;

MAMMALIA;

EID: 38649116610     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9628-x     Document Type: Article

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