메뉴 건너뛰기




Volumn 54, Issue 9, 2013, Pages 2458-2474

RDH10, RALDH2, and CRABP2 are required components of PPAR γ-directed ATRA synthesis and signaling in human dendritic cells

Author keywords

All trans retinoic acid; Cellular retinoic acid binding protein 2; INKT cells; Lipid antigen presentation; Lipid transport; Peroxisome proliferator activated receptor ; Retinoic acid receptor signaling; Retinoid metabolism

Indexed keywords

CARRIER PROTEIN; CD103 ANTIGEN; CELL PROTEIN; CELLULAR RETINOIC ACID BINDING PROTEIN 2; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN RALDH2; PROTEIN RDH10; RETINOIC ACID; UNCLASSIFIED DRUG;

EID: 84883151744     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M038984     Document Type: Article
Times cited : (24)

References (65)
  • 1
    • 26844538936 scopus 로고    scopus 로고
    • Functional specialization of gut CD103+ dendritic cells in the regulation of tissueselective T cell homing
    • Johansson-Lindbom, B., M. Svensson, O. Pabst, C. Palmqvist, G. Marquez, R. Forster, and W. W. Agace. 2005. Functional specialization of gut CD103+ dendritic cells in the regulation of tissueselective T cell homing. J. Exp. Med. 202: 1063-1073.
    • (2005) J. Exp. Med , vol.202 , pp. 1063-1073
    • Johansson-Lindbom, B.1    Svensson, M.2    Pabst, O.3    Palmqvist, C.4    Marquez, G.5    Forster, R.6    Agace, W.W.7
  • 2
    • 73949107838 scopus 로고    scopus 로고
    • Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
    • Schulz, O., E. Jaensson, E. K. Persson, X. Liu, T. Worbs, W. W. Agace, and O. Pabst. 2009. Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 206: 3101-3114.
    • (2009) J. Exp. Med , vol.206 , pp. 3101-3114
    • Schulz, O.1    Jaensson, E.2    Persson, E.K.3    Liu, X.4    Worbs, T.5    Agace, W.W.6    Pabst, O.7
  • 7
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes, J. L., K. R. Siddiqui, C. V. Arancibia-Carcamo, J. Hall, C. M. Sun, Y. Belkaid, and F. Powrie. 2007. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 204: 1757-1764.
    • (2007) J. Exp. Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6    Powrie, F.7
  • 8
    • 0141886178 scopus 로고    scopus 로고
    • CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells
    • Sato, A., M. Hashiguchi, E. Toda, A. Iwasaki, S. Hachimura, and S. Kaminogawa. 2003. CD11b+ Peyer's patch dendritic cells secrete IL-6 and induce IgA secretion from naive B cells. J. Immunol. 171: 3684-3690.
    • (2003) J. Immunol , vol.171 , pp. 3684-3690
    • Sato, A.1    Hashiguchi, M.2    Toda, E.3    Iwasaki, A.4    Hachimura, S.5    Kaminogawa, S.6
  • 9
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun, C. M., J. A. Hall, R. B. Blank, N. Bouladoux, M. Oukka, J. R. Mora, and Y. Belkaid. 2007. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204: 1775-1785.
    • (2007) J. Exp. Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6    Belkaid, Y.7
  • 11
    • 83255187847 scopus 로고    scopus 로고
    • Physiological insights into all-trans-retinoic acid biosynthesis
    • Napoli, J. L. 2012. Physiological insights into all-trans-retinoic acid biosynthesis. Biochim. Biophys. Acta. 1821: 152-167.
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 152-167
    • Napoli, J.L.1
  • 13
    • 35349027768 scopus 로고    scopus 로고
    • Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation
    • Cammas, L., R. Romand, V. Fraulob, C. Mura, and P. Dolle. 2007. Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev. Dyn. 236: 2899-2908.
    • (2007) Dev. Dyn , vol.236 , pp. 2899-2908
    • Cammas, L.1    Romand, R.2    Fraulob, V.3    Mura, C.4    Dolle, P.5
  • 14
    • 63649135273 scopus 로고    scopus 로고
    • GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity
    • Yokota, A., H. Takeuchi, N. Maeda, Y. Ohoka, C. Kato, S. Y. Song, and M. Iwata. 2009. GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity. Int. Immunol. 21: 361-377.
    • (2009) Int. Immunol , vol.21 , pp. 361-377
    • Yokota, A.1    Takeuchi, H.2    Maeda, N.3    Ohoka, Y.4    Kato, C.5    Song, S.Y.6    Iwata, M.7
  • 15
    • 83255187861 scopus 로고    scopus 로고
    • Alcohol and aldehyde dehydrogenases: Retinoid metabolic effects in mouse knockout models
    • Kumar, S., L. L. Sandell, P. A. Trainor, F. Koentgen, and G. Duester. 2012. Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models. Biochim. Biophys. Acta. 1821: 198-205.
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 198-205
    • Kumar, S.1    Sandell, L.L.2    Trainor, P.A.3    Koentgen, F.4    Duester, G.5
  • 16
    • 0036337341 scopus 로고    scopus 로고
    • Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice
    • Mic, F. A., R. J. Haselbeck, A. E. Cuenca, and G. Duester. 2002. Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development. 129: 2271-2282.
    • (2002) Development , vol.129 , pp. 2271-2282
    • Mic, F.A.1    Haselbeck, R.J.2    Cuenca, A.E.3    Duester, G.4
  • 17
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse postimplantation development
    • Niederreither, K., V. Subbarayan, P. Dolle, and P. Chambon. 1999. Embryonic retinoic acid synthesis is essential for early mouse postimplantation development. Nat. Genet. 21: 444-448.
    • (1999) Nat. Genet , vol.21 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dolle, P.3    Chambon, P.4
  • 18
    • 0035028993 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse
    • Niederreither, K., J. Vermot, N. Messaddeq, B. Schuhbaur, P. Chambon, and P. Dolle. 2001. Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse. Development. 128: 1019-1031.
    • (2001) Development , vol.128 , pp. 1019-1031
    • Niederreither, K.1    Vermot, J.2    Messaddeq, N.3    Schuhbaur, B.4    Chambon, P.5    Dolle, P.6
  • 19
    • 0029794132 scopus 로고    scopus 로고
    • A decade of molecular biology of retinoic acid receptors
    • Chambon, P. 1996. A decade of molecular biology of retinoic acid receptors. FASEB J. 10: 940-954.
    • (1996) FASEB J , vol.10 , pp. 940-954
    • Chambon, P.1
  • 20
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf, D. J., and R. M. Evans. 1995. The RXR heterodimers and orphan receptors. Cell. 83: 841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 21
    • 0023756692 scopus 로고
    • Retinoic acid and thyroid hormone induce gene expression through a common responsive element
    • Umesono, K., V. Giguere, C. K. Glass, M. G. Rosenfeld, and R. M. Evans. 1988. Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature. 336: 262-265.
    • (1988) Nature , vol.336 , pp. 262-265
    • Umesono, K.1    Giguere, V.2    Glass, C.K.3    Rosenfeld, M.G.4    Evans, R.M.5
  • 23
    • 3142688053 scopus 로고    scopus 로고
    • Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion
    • Szatmari, I., P. Gogolak, J. S. Im, B. Dezso, E. Rajnavolgyi, and L. Nagy. 2004. Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity. 21: 95-106.
    • (2004) Immunity , vol.21 , pp. 95-106
    • Szatmari, I.1    Gogolak, P.2    Im, J.S.3    Dezso, B.4    Rajnavolgyi, E.5    Nagy, L.6
  • 24
    • 33749318770 scopus 로고    scopus 로고
    • PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells
    • Szatmari, I., A. Pap, R. Ruhl, J. X. Ma, P. A. Illarionov, G. S. Besra, E. Rajnavolgyi, B. Dezso, and L. Nagy. 2006. PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. J. Exp. Med. 203: 2351-2362.
    • (2006) J. Exp. Med , vol.203 , pp. 2351-2362
    • Szatmari, I.1    Pap, A.2    Ruhl, R.3    Ma, J.X.4    Illarionov, P.A.5    Besra, G.S.6    Rajnavolgyi, E.7    Dezso, B.8    Nagy, L.9
  • 26
    • 0032971371 scopus 로고    scopus 로고
    • The CD1 system: Antigenpresenting molecules for T cell recognition of lipids and glycolipids
    • Porcelli, S. A., and R. L. Modlin. 1999. The CD1 system: antigenpresenting molecules for T cell recognition of lipids and glycolipids. Annu. Rev. Immunol. 17: 297-329.
    • (1999) Annu. Rev. Immunol , vol.17 , pp. 297-329
    • Porcelli, S.A.1    Modlin, R.L.2
  • 27
    • 14044261257 scopus 로고    scopus 로고
    • Generation of an optimized polyvalent monocyte-derived dendritic cell vaccine by transfecting defined RNAs after rather than before maturation
    • Schaft, N., J. Dorrie, P. Thumann, V. E. Beck, I. Muller, E. S. Schultz, E. Kampgen, D. Dieckmann, and G. Schuler. 2005. Generation of an optimized polyvalent monocyte-derived dendritic cell vaccine by transfecting defined RNAs after rather than before maturation. J. Immunol. 174: 3087-3097.
    • (2005) J. Immunol , vol.174 , pp. 3087-3097
    • Schaft, N.1    Dorrie, J.2    Thumann, P.3    Beck, V.E.4    Muller, I.5    Schultz, E.S.6    Kampgen, E.7    Dieckmann, D.8    Schuler, G.9
  • 28
    • 33846210355 scopus 로고    scopus 로고
    • Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma
    • Gogolak, P., B. Rethi, I. Szatmari, A. Lanyi, B. Dezso, L. Nagy, and E. Rajnavolgyi. 2007. Differentiation of CD1a- and CD1a+ monocyte-derived dendritic cells is biased by lipid environment and PPARgamma. Blood. 109: 643-652.
    • (2007) Blood , vol.109 , pp. 643-652
    • Gogolak, P.1    Rethi, B.2    Szatmari, I.3    Lanyi, A.4    Dezso, B.5    Nagy, L.6    Rajnavolgyi, E.7
  • 30
    • 28044448712 scopus 로고    scopus 로고
    • Transcriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibility
    • Loudig, O., G. A. Maclean, N. L. Dore, L. Luu, and M. Petkovich. 2005. Transcriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibility. Biochem. J. 392: 241-248.
    • (2005) Biochem. J , vol.392 , pp. 241-248
    • Loudig, O.1    Maclean, G.A.2    Dore, N.L.3    Luu, L.4    Petkovich, M.5
  • 31
    • 0030810985 scopus 로고    scopus 로고
    • CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family
    • Ray, W. J., G. Bain, M. Yao, and D. I. Gottlieb. 1997. CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family. J. Biol. Chem. 272: 18702-18708.
    • (1997) J. Biol. Chem , vol.272 , pp. 18702-18708
    • Ray, W.J.1    Bain, G.2    Yao, M.3    Gottlieb, D.I.4
  • 32
    • 0023726975 scopus 로고
    • The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages
    • Chiocca, E. A., P. J. Davies, and J. P. Stein. 1988. The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages. J. Biol. Chem. 263: 11584-11589.
    • (1988) J. Biol. Chem , vol.263 , pp. 11584-11589
    • Chiocca, E.A.1    Davies, P.J.2    Stein, J.P.3
  • 33
    • 33846946440 scopus 로고    scopus 로고
    • A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A
    • Kawaguchi, R., J. Yu, J. Honda, J. Hu, J. Whitelegge, P. Ping, P. Wiita, D. Bok, and H. Sun. 2007. A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science. 315: 820-825.
    • (2007) Science , vol.315 , pp. 820-825
    • Kawaguchi, R.1    Yu, J.2    Honda, J.3    Hu, J.4    Whitelegge, J.5    Ping, P.6    Wiita, P.7    Bok, D.8    Sun, H.9
  • 34
    • 79953780312 scopus 로고    scopus 로고
    • The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor
    • Sun, H., and R. Kawaguchi. 2011. The membrane receptor for plasma retinol-binding protein, a new type of cell-surface receptor. Int. Rev. Cell Mol. Biol. 288: 1-41.
    • (2011) Int. Rev. Cell Mol. Biol , vol.288 , pp. 1-41
    • Sun, H.1    Kawaguchi, R.2
  • 38
    • 0034777941 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells
    • Gosset, P., A. S. Charbonnier, P. Delerive, J. Fontaine, B. Staels, J. Pestel, A. B. Tonnel, and F. Trottein. 2001. Peroxisome proliferator-activated receptor gamma activators affect the maturation of human monocyte-derived dendritic cells. Eur. J. Immunol. 31: 2857-2865.
    • (2001) Eur. J. Immunol , vol.31 , pp. 2857-2865
    • Gosset, P.1    Charbonnier, A.S.2    Delerive, P.3    Fontaine, J.4    Staels, B.5    Pestel, J.6    Tonnel, A.B.7    Trottein, F.8
  • 39
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179: 1109-1118.
    • (1994) J. Exp. Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 41
    • 26844581978 scopus 로고    scopus 로고
    • Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells
    • Lindstedt, M., K. Lundberg, and C. A. Borrebaeck. 2005. Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells. J. Immunol. 175: 4839-4846.
    • (2005) J. Immunol , vol.175 , pp. 4839-4846
    • Lindstedt, M.1    Lundberg, K.2    Borrebaeck, C.A.3
  • 42
    • 46949086238 scopus 로고    scopus 로고
    • Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: Differential activation states suggest distinct functions
    • Santegoets, S. J., S. Gibbs, K. Kroeze, R. van de Ven, R. J. Scheper, C. A. Borrebaeck, T. D. de Gruijl, and M. Lindstedt. 2008. Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: differential activation states suggest distinct functions. J. Leukoc. Biol. 84: 143-151.
    • (2008) J. Leukoc. Biol , vol.84 , pp. 143-151
    • Santegoets, S.J.1    Gibbs, S.2    Kroeze, K.3    Ven De R.Van4    Scheper, R.J.5    Borrebaeck, C.A.6    De Gruijl, T.D.7    Lindstedt, M.8
  • 43
    • 36148982257 scopus 로고    scopus 로고
    • PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism
    • Szatmari, I., D. Torocsik, M. Agostini, T. Nagy, M. Gurnell, E. Barta, K. Chatterjee, and L. Nagy. 2007. PPARgamma regulates the function of human dendritic cells primarily by altering lipid metabolism. Blood. 110: 3271-3280.
    • (2007) Blood , vol.110 , pp. 3271-3280
    • Szatmari, I.1    Torocsik, D.2    Agostini, M.3    Nagy, T.4    Gurnell, M.5    Barta, E.6    Chatterjee, K.7    Nagy, L.8
  • 44
    • 78049342781 scopus 로고    scopus 로고
    • Research resource: Transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte- derived dendritic cells
    • Széles, L., S. Póliska, G. Nagy, I. Szatmari, A. Szanto, A. Pap, M. Lindstedt, S. J. Santegoets, R. Rühl, B. Dezsö, et al. 2010. Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte- derived dendritic cells. Mol. Endocrinol. 24: 2218-2231.
    • (2010) Mol. Endocrinol , vol.24 , pp. 2218-2231
    • Széles, L.1    Póliska, S.2    Nagy, G.3    Szatmari, I.4    Szanto, A.5    Pap, A.6    Lindstedt, M.7    Santegoets, S.J.8    Rühl, R.9    Dezsö, B.10
  • 45
    • 0028180070 scopus 로고
    • MPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
    • Tontonoz, P., E. Hu, R. A. Graves, A. I. Budavari, and B. M. Spiegelman. 1994. mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8: 1224-1234.
    • (1994) Genes Dev , vol.8 , pp. 1224-1234
    • Tontonoz, P.1    Hu, E.2    Graves, R.A.3    Budavari, A.I.4    Spiegelman, B.M.5
  • 46
    • 0032875365 scopus 로고    scopus 로고
    • Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex
    • Delva, L., J. N. Bastie, C. Rochette-Egly, R. Kraiba, N. Balitrand, G. Despouy, P. Chambon, and C. Chomienne. 1999. Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex. Mol. Cell. Biol. 19: 7158-7167.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 7158-7167
    • Delva, L.1    Bastie, J.N.2    Rochette-Egly, C.3    Kraiba, R.4    Balitrand, N.5    Despouy, G.6    Chambon, P.7    Chomienne, C.8
  • 47
    • 0033588225 scopus 로고    scopus 로고
    • Distinct roles for cellular retinoic acid-binding proteins i and II in regulating signaling by retinoic acid
    • Dong, D., S. E. Ruuska, D. J. Levinthal, and N. Noy. 1999. Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. J. Biol. Chem. 274: 23695-23698.
    • (1999) J. Biol. Chem , vol.274 , pp. 23695-23698
    • Dong, D.1    Ruuska, S.E.2    Levinthal, D.J.3    Noy, N.4
  • 49
    • 45549092696 scopus 로고    scopus 로고
    • Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells
    • Elgueta, R., F. E. Sepulveda, F. Vilches, L. Vargas, J. R. Mora, M. R. Bono, and M. Rosemblatt. 2008. Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells. J. Immunol. 180: 6501-6507.
    • (2008) J. Immunol , vol.180 , pp. 6501-6507
    • Elgueta, R.1    Sepulveda, F.E.2    Vilches, F.3    Vargas, L.4    Mora, J.R.5    Bono, M.R.6    Rosemblatt, M.7
  • 50
    • 78650645161 scopus 로고    scopus 로고
    • Generation of mucosal dendritic cells from bone marrow reveals a critical role of retinoic acid
    • Feng, T., Y. Cong, H. Qin, E. N. Benveniste, and C. O. Elson. 2010. Generation of mucosal dendritic cells from bone marrow reveals a critical role of retinoic acid. J. Immunol. 185: 5915-5925.
    • (2010) J. Immunol , vol.185 , pp. 5915-5925
    • Feng, T.1    Cong, Y.2    Qin, H.3    Benveniste, E.N.4    Elson, C.O.5
  • 52
    • 64149088746 scopus 로고    scopus 로고
    • Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
    • Manicassamy, S., R. Ravindran, J. Deng, H. Oluoch, T. L. Denning, S. P. Kasturi, K. M. Rosenthal, B. D. Evavold, and B. Pulendran. 2009. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat. Med. 15: 401-409.
    • (2009) Nat. Med , vol.15 , pp. 401-409
    • Manicassamy, S.1    Ravindran, R.2    Deng, J.3    Oluoch, H.4    Denning, T.L.5    Kasturi, S.P.6    Rosenthal, K.M.7    Evavold, B.D.8    Pulendran, B.9
  • 53
    • 34249087361 scopus 로고    scopus 로고
    • Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors
    • Schug, T. T., D. C. Berry, N. S. Shaw, S. N. Travis, and N. Noy. 2007. Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell. 129: 723-733.
    • (2007) Cell , vol.129 , pp. 723-733
    • Schug, T.T.1    Berry, D.C.2    Shaw, N.S.3    Travis, S.N.4    Noy, N.5
  • 56
    • 33746159991 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease
    • Adachi, M., R. Kurotani, K. Morimura, Y. Shah, M. Sanford, B. B. Madison, D. L. Gumucio, H. E. Marin, J. M. Peters, H. A. Young, et al. 2006. Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease. Gut. 55: 1104-1113.
    • (2006) Gut , vol.55 , pp. 1104-1113
    • Adachi, M.1    Kurotani, R.2    Morimura, K.3    Shah, Y.4    Sanford, M.5    Madison, B.B.6    Gumucio, D.L.7    Marin, H.E.8    Peters, J.M.9    Young, H.A.10
  • 59
    • 0035794293 scopus 로고    scopus 로고
    • Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator- activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies
    • Desreumaux, P., L. Dubuquoy, S. Nutten, M. Peuchmaur, W. Englaro, K. Schoonjans, B. Derijard, B. Desvergne, W. Wahli, P. Chambon, et al. 2001. Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator- activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies. J. Exp. Med. 193: 827-838.
    • (2001) J. Exp. Med , vol.193 , pp. 827-838
    • Desreumaux, P.1    Dubuquoy, L.2    Nutten, S.3    Peuchmaur, M.4    Englaro, W.5    Schoonjans, K.6    Derijard, B.7    Desvergne, B.8    Wahli, W.9    Chambon, P.10
  • 60
    • 33847039159 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis
    • Shah, Y. M., K. Morimura, and F. J. Gonzalez. 2007. Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G657-G666.
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol , vol.292
    • Shah, Y.M.1    Morimura, K.2    Gonzalez, F.J.3
  • 61
    • 4143052336 scopus 로고    scopus 로고
    • Secondgeneration thiazolidinediones and hepatotoxicity
    • Marcy, T. R., M. L. Britton, and S. M. Blevins. 2004. Secondgeneration thiazolidinediones and hepatotoxicity. Ann. Pharmacother. 38: 1419-1423.
    • (2004) Ann. Pharmacother , vol.38 , pp. 1419-1423
    • Marcy, T.R.1    Britton, M.L.2    Blevins, S.M.3
  • 62
    • 0344304678 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure: A consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003
    • Nesto, R. W., D. Bell, R. O. Bonow, V. Fonseca, S. M. Grundy, E. S. Horton, M. Le Winter, D. Porte, C. F. Semenkovich, S. Smith, et al. 2003. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003. Circulation. 108: 2941-2948.
    • (2003) Circulation , vol.108 , pp. 2941-2948
    • Nesto, R.W.1    Bell, D.2    Bonow, R.O.3    Fonseca, V.4    Grundy, S.M.5    Horton, E.S.6    Le Winter, M.7    Porte, D.8    Semenkovich, C.F.9    Smith, S.10
  • 65
    • 15944422109 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency
    • Lytle, C., T. J. Tod, K. T. Vo, J. W. Lee, R. D. Atkinson, and D. S. Straus. 2005. The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency. Inflamm. Bowel Dis. 11: 231-243.
    • (2005) Inflamm. Bowel Dis , vol.11 , pp. 231-243
    • Lytle, C.1    Tod, T.J.2    Vo, K.T.3    Lee, J.W.4    Atkinson, R.D.5    Straus, D.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.