-
1
-
-
0031572858
-
The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: Multiple copy flexibility and receptor binding
-
YA Muller, HW Christinger, BA Keyt and AM de Vos (1997) The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93A resolution: multiple copy flexibility and receptor binding. Structure 5 1325-1338.
-
(1997)
Structure
, vol.5
, pp. 1325-1338
-
-
Muller, Y.A.1
Christinger, H.W.2
Keyt, B.A.3
de Vos, A.M.4
-
2
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
D Shweiki, A Itin, D Soffer and E Keshet (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359 843-845.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
3
-
-
25144511910
-
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
-
H Takahashi and M Shibuya (2005) The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clin Sci (Lond) 109 227-241.
-
(2005)
Clin Sci (Lond)
, vol.109
, pp. 227-241
-
-
Takahashi, H.1
Shibuya, M.2
-
4
-
-
12544258730
-
Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: Insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1
-
K Suto, Y Yamazaki, T Morita and H Mizuno (2005) Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1. J Biol Chem 280 2126-2131.
-
(2005)
J Biol Chem
, vol.280
, pp. 2126-2131
-
-
Suto, K.1
Yamazaki, Y.2
Morita, T.3
Mizuno, H.4
-
5
-
-
33646401513
-
Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster
-
W Wood, C Faria and A Jacinto (2006) Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. J Cell Biol 173 405-416.
-
(2006)
J Cell Biol
, vol.173
, pp. 405-416
-
-
Wood, W.1
Faria, C.2
Jacinto, A.3
-
6
-
-
33847630758
-
Structure of a VEGF-VEGF receptor complex determined by electron microscopy
-
C Ruch, G Skiniotis, MO Steinmetz, T Walz and K Ballmer-Hofer (2007) Structure of a VEGF-VEGF receptor complex determined by electron microscopy. Nat Struct Mol Biol 14 249-250.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 249-250
-
-
Ruch, C.1
Skiniotis, G.2
Steinmetz, M.O.3
Walz, T.4
Ballmer-Hofer, K.5
-
7
-
-
17044458971
-
Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites
-
J Dixelius, T Makinen, M Wirzenius, MJ Karkkainen, C Wernstedt, K Alitalo and L Claesson-Welsh (2003) Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites. J Biol Chem 278 40,973-40,979.
-
(2003)
J Biol Chem
, vol.278
, pp. 40,973-40,979
-
-
Dixelius, J.1
Makinen, T.2
Wirzenius, M.3
Karkkainen, M.J.4
Wernstedt, C.5
Alitalo, K.6
Claesson-Welsh, L.7
-
8
-
-
0035051886
-
Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers
-
K Huang, C Andersson, GM Roomans, N Ito and L Claesson-Welsh (2001) Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers. Intl J Biochem Cell Biol 33 315-324.
-
(2001)
Intl J Biochem Cell Biol
, vol.33
, pp. 315-324
-
-
Huang, K.1
Andersson, C.2
Roomans, G.M.3
Ito, N.4
Claesson-Welsh, L.5
-
9
-
-
49949152181
-
Vascular permeability, vascular hyperpermeability and angiogenesis
-
in press
-
Nagy JA, Benjamin L, Zeng H, Dvorak AM, Dvorak HF. Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis 2008. in press.
-
(2008)
Angiogenesis
-
-
Nagy, J.A.1
Benjamin, L.2
Zeng, H.3
Dvorak, A.M.4
Dvorak, H.F.5
-
10
-
-
35348879042
-
Similarities between angiogenesis and neural development: What small animal models can tell us
-
S Zacchigna, C Ruiz de Almodovar and P Carmeliet (2008) Similarities between angiogenesis and neural development: what small animal models can tell us. Curr Topics Dev Biol 80 1-55.
-
(2008)
Curr Topics Dev Biol
, vol.80
, pp. 1-55
-
-
Zacchigna, S.1
Ruiz de Almodovar, C.2
Carmeliet, P.3
-
11
-
-
34547582336
-
Endothelial precursor cell migration during vasculogenesis
-
A Schmidt, K Brixius and W Bloch (2007) Endothelial precursor cell migration during vasculogenesis. Circ Res 101 125-136.
-
(2007)
Circ Res
, vol.101
, pp. 125-136
-
-
Schmidt, A.1
Brixius, K.2
Bloch, W.3
-
12
-
-
33750286135
-
The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
-
F Bertolini, Y Shaked, P Mancuso and RS Kerbel (2006) The multifaceted circulating endothelial cell in cancer: towards marker and target identification. Nat Rev Cancer 6 835-845.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 835-845
-
-
Bertolini, F.1
Shaked, Y.2
Mancuso, P.3
Kerbel, R.S.4
-
13
-
-
0037815292
-
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
-
H Gerhardt, M Golding, M Fruttiger, C Ruhrberg, A Lundkvist, A Abramsson, M Jeltsch, C Mitchell, K Alitalo, D Shima and C Betsholtz (2003) VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 161 1163-1177.
-
(2003)
J Cell Biol
, vol.161
, pp. 1163-1177
-
-
Gerhardt, H.1
Golding, M.2
Fruttiger, M.3
Ruhrberg, C.4
Lundkvist, A.5
Abramsson, A.6
Jeltsch, M.7
Mitchell, C.8
Alitalo, K.9
Shima, D.10
Betsholtz, C.11
-
14
-
-
41649088181
-
Modulation of VEGF signalling output by the Notch pathway
-
AF Siekmann, L Covassin and ND Lawson (2008) Modulation of VEGF signalling output by the Notch pathway. Bioessays 30 303-313.
-
(2008)
Bioessays
, vol.30
, pp. 303-313
-
-
Siekmann, A.F.1
Covassin, L.2
Lawson, N.D.3
-
15
-
-
6944234979
-
Intussusceptive angiogenesis: Its emergence, its characteristics, and its significance
-
PH Burri, R Hlushchuk and V Djonov (2004) Intussusceptive angiogenesis: its emergence, its characteristics, and its significance. Dev Dyn 231 474-488.
-
(2004)
Dev Dyn
, vol.231
, pp. 474-488
-
-
Burri, P.H.1
Hlushchuk, R.2
Djonov, V.3
-
16
-
-
0033515089
-
In vitro hematopoietic and endothelial potential of flk-1(−/−) embryonic stem cells and embryos
-
AC Schuh, P Faloon, QL Hu, M Bhimani and K Choi (1999) In vitro hematopoietic and endothelial potential of flk-1(−/−) embryonic stem cells and embryos. Proc Natl Acad Sci USA 96 2159-2164.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2159-2164
-
-
Schuh, A.C.1
Faloon, P.2
Hu, Q.L.3
Bhimani, M.4
Choi, K.5
-
17
-
-
37349116739
-
Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1−/− embryonic stem cells shows early priming of endothelial precursors
-
X Li, D Edholm, F Lanner, G Breier, F Farnebo, A Dimberg and L Claesson-Welsh (2007) Lentiviral rescue of vascular endothelial growth factor receptor-2 expression in flk1−/− embryonic stem cells shows early priming of endothelial precursors. Stem Cells 25 2987-2995.
-
(2007)
Stem Cells
, vol.25
, pp. 2987-2995
-
-
Li, X.1
Edholm, D.2
Lanner, F.3
Breier, G.4
Farnebo, F.5
Dimberg, A.6
Claesson-Welsh, L.7
-
18
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
F Shalaby, J Rossant, TP Yamaguchi, M Gertsenstein, XF Wu, ML Breitman and AC Schuh (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376 62-66.
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
Rossant, J.2
Yamaguchi, T.P.3
Gertsenstein, M.4
Wu, X.F.5
Breitman, M.L.6
Schuh, A.C.7
-
19
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
P Carmeliet, V Ferreira, G Breier, S Pollefeyt, L Kieckens, M Gertsenstein, M Fahrig, A Vandenhoeck, K Harpal, C Eberhardt, C Declercq, J Pawling, L Moons, D Collen, W Risau and A Nagy (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
Fahrig, M.7
Vandenhoeck, A.8
Harpal, K.9
Eberhardt, C.10
Declercq, C.11
Pawling, J.12
Moons, L.13
Collen, D.14
Risau, W.15
Nagy, A.16
-
21
-
-
0030004485
-
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
-
N Ferrara, K Carver-Moore, H Chen, M Dowd, L Lu, KS O’Shea, L Powell-Braxton, KJ Hillan and MW Moore (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380 439-442.
-
(1996)
Nature
, vol.380
, pp. 439-442
-
-
Ferrara, N.1
Carver-Moore, K.2
Chen, H.3
Dowd, M.4
Lu, L.5
O’Shea, K.S.6
Powell-Braxton, L.7
Hillan, K.J.8
Moore, M.W.9
-
22
-
-
0036174063
-
Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms
-
I Stalmans, YS Ng, R Rohan, M Fruttiger, A Bouche, A Yuce, H Fujisawa, B Hermans, M Shani, S Jansen, D Hicklin, DJ Anderson, T Gardiner, HP Hammes, L Moons, M Dewerchin, D Collen, P Carmeliet and PA D’Amore (2002) Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest 109 327-336.
-
(2002)
J Clin Invest
, vol.109
, pp. 327-336
-
-
Stalmans, I.1
Ng, Y.S.2
Rohan, R.3
Fruttiger, M.4
Bouche, A.5
Yuce, A.6
Fujisawa, H.7
Hermans, B.8
Shani, M.9
Jansen, S.10
Hicklin, D.11
Anderson, D.J.12
Gardiner, T.13
Hammes, H.P.14
Moons, L.15
Dewerchin, M.16
Collen, D.17
Carmeliet, P.18
D’Amore, P.A.19
-
23
-
-
0032925156
-
Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
P Carmeliet, YS Ng, D Nuyens, G Theilmeier, K Brusselmans, I Cornelissen, E Ehler, VV Kakkar, I Stalmans, V Mattot, JC Perriard, M Dewerchin, W Flameng, A Nagy, F Lupu, L Moons, D Collen, PA D’Amore and DT Shima (1999) Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat Med 5 495-502.
-
(1999)
Nat Med
, vol.5
, pp. 495-502
-
-
Carmeliet, P.1
Ng, Y.S.2
Nuyens, D.3
Theilmeier, G.4
Brusselmans, K.5
Cornelissen, I.6
Ehler, E.7
Kakkar, V.V.8
Stalmans, I.9
Mattot, V.10
Perriard, J.C.11
Dewerchin, M.12
Flameng, W.13
Nagy, A.14
Lupu, F.15
Moons, L.16
Collen, D.17
D’Amore, P.A.18
Shima, D.T.19
-
24
-
-
0036339867
-
Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis
-
E Zelzer, W McLean, YS Ng, N Fukai, AM Reginato, S Lovejoy, PA D’Amore and BR Olsen (2002) Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development 129 1893-1904.
-
(2002)
Development
, vol.129
, pp. 1893-1904
-
-
Zelzer, E.1
McLean, W.2
Ng, Y.S.3
Fukai, N.4
Reginato, A.M.5
Lovejoy, S.6
D’Amore, P.A.7
Olsen, B.R.8
-
25
-
-
0036166701
-
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
-
C Maes, P Carmeliet, K Moermans, I Stockmans, N Smets, D Collen, R Bouillon and G Carmeliet (2002) Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech Dev 111 61-73.
-
(2002)
Mech Dev
, vol.111
, pp. 61-73
-
-
Maes, C.1
Carmeliet, P.2
Moermans, K.3
Stockmans, I.4
Smets, N.5
Collen, D.6
Bouillon, R.7
Carmeliet, G.8
-
26
-
-
1342289558
-
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival
-
C Maes, I Stockmans, K Moermans, R Van Looveren, N Smets, P Carmeliet, R Bouillon and G Carmeliet (2004) Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest 113 188-199.
-
(2004)
J Clin Invest
, vol.113
, pp. 188-199
-
-
Maes, C.1
Stockmans, I.2
Moermans, K.3
Van Looveren, R.4
Smets, N.5
Carmeliet, P.6
Bouillon, R.7
Carmeliet, G.8
-
27
-
-
0033602091
-
Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization
-
M Dougher and BI Terman (1999) Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization. Oncogene 18 1619-1627.
-
(1999)
Oncogene
, vol.18
, pp. 1619-1627
-
-
Dougher, M.1
Terman, B.I.2
-
28
-
-
0034051161
-
VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor
-
LW Wu, LD Mayo, JD Dunbar, KM Kessler, ON Ozes, RS Warren and DB Donner (2000) VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor. J Biol Chem 275 6059-6062.
-
(2000)
J Biol Chem
, vol.275
, pp. 6059-6062
-
-
Wu, L.W.1
Mayo, L.D.2
Dunbar, J.D.3
Kessler, K.M.4
Ozes, O.N.5
Warren, R.S.6
Donner, D.B.7
-
29
-
-
22744447871
-
VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis
-
T Matsumoto, S Bohman, J Dixelius, T Berge, A Dimberg, P Magnusson, L Wang, C Wikner, JH Qi, C Wernstedt, J Wu, S Bruheim, H Mugishima, D Mukhopadhyay, A Spurkland and L Claesson-Welsh (2005) VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis. EMBO J 24 2342-2353.
-
(2005)
EMBO J
, vol.24
, pp. 2342-2353
-
-
Matsumoto, T.1
Bohman, S.2
Dixelius, J.3
Berge, T.4
Dimberg, A.5
Magnusson, P.6
Wang, L.7
Wikner, C.8
Qi, J.H.9
Wernstedt, C.10
Wu, J.11
Bruheim, S.12
Mugishima, H.13
Mukhopadhyay, D.14
Spurkland, A.15
Claesson-Welsh, L.16
-
30
-
-
0033393771
-
Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
-
BP Eliceiri, R Paul, PL Schwartzberg, JD Hood, J Leng and DA Cheresh (1999) Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell 4 915-924.
-
(1999)
Mol Cell
, vol.4
, pp. 915-924
-
-
Eliceiri, B.P.1
Paul, R.2
Schwartzberg, P.L.3
Hood, J.D.4
Leng, J.5
Cheresh, D.A.6
-
31
-
-
11144357189
-
Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction
-
S Weis, S Shintani, A Weber, R Kirchmair, M Wood, A Cravens, H McSharry, A Iwakura, YS Yoon, N Himes, D Burstein, J Doukas, R Soll, D Losordo and D Cheresh (2004) Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. J Clin Invest 113 885-894.
-
(2004)
J Clin Invest
, vol.113
, pp. 885-894
-
-
Weis, S.1
Shintani, S.2
Weber, A.3
Kirchmair, R.4
Wood, M.5
Cravens, A.6
McSharry, H.7
Iwakura, A.8
Yoon, Y.S.9
Himes, N.10
Burstein, D.11
Doukas, J.12
Soll, R.13
Losordo, D.14
Cheresh, D.15
-
32
-
-
0035355472
-
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells
-
T Takahashi, S Yamaguchi, K Chida and M Shibuya (2001) A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J 20 2768-2778.
-
(2001)
EMBO J
, vol.20
, pp. 2768-2778
-
-
Takahashi, T.1
Yamaguchi, S.2
Chida, K.3
Shibuya, M.4
-
33
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
T Takahashi, H Ueno and M Shibuya (1999) VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 18 2221-2231.
-
(1999)
Oncogene
, vol.18
, pp. 2221-2231
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
34
-
-
12844264070
-
Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice
-
Y Sakurai, K Ohgimoto, Y Kataoka, N Yoshida and M Shibuya (2005) Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci USA 102 1076-1081.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 1076-1081
-
-
Sakurai, Y.1
Ohgimoto, K.2
Kataoka, Y.3
Yoshida, N.4
Shibuya, M.5
-
35
-
-
2542455474
-
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration
-
K Holmqvist, MJ Cross, C Rolny, R Hagerkvist, N Rahimi, T Matsumoto, L Claesson-Welsh and M Welsh (2004) The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. J Biol Chem 279 22,267-22,275.
-
(2004)
J Biol Chem
, vol.279
, pp. 22,267-22,275
-
-
Holmqvist, K.1
Cross, M.J.2
Rolny, C.3
Hagerkvist, R.4
Rahimi, N.5
Matsumoto, T.6
Claesson-Welsh, L.7
Welsh, M.8
-
36
-
-
0034655369
-
The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells
-
AJ Warner, J Lopez-Dee, EL Knight, JR Feramisco and SA Prigent (2000) The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells. Biochem J 347 501-509.
-
(2000)
Biochem J
, vol.347
, pp. 501-509
-
-
Warner, A.J.1
Lopez-Dee, J.2
Knight, E.L.3
Feramisco, J.R.4
Prigent, S.A.5
-
37
-
-
0037088684
-
Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice
-
HJ Liao, T Kume, C McKay, MJ Xu, JN Ihle and G Carpenter (2002) Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. J Biol Chem 277 9335-9341.
-
(2002)
J Biol Chem
, vol.277
, pp. 9335-9341
-
-
Liao, H.J.1
Kume, T.2
McKay, C.3
Xu, M.J.4
Ihle, J.N.5
Carpenter, G.6
-
38
-
-
0038624399
-
phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development
-
ND Lawson, JW Mugford, BA Diamond and BM Weinstein (2003) phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev 17 1346-1351.
-
(2003)
Genes Dev
, vol.17
, pp. 1346-1351
-
-
Lawson, N.D.1
Mugford, J.W.2
Diamond, B.A.3
Weinstein, B.M.4
-
39
-
-
44349119736
-
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration
-
M Graupera, J Guillermet-Guibert, LC Foukas, LK Phng, RJ Cain, A Salpekar, W Pearce, S Meek, J Millan, PR Cutillas, AJ Smith, AJ Ridley, C Ruhrberg, H Gerhardt and B Vanhaesebroeck (2008) Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. Nature 453 662-666.
-
(2008)
Nature
, vol.453
, pp. 662-666
-
-
Graupera, M.1
Guillermet-Guibert, J.2
Foukas, L.C.3
Phng, L.K.4
Cain, R.J.5
Salpekar, A.6
Pearce, W.7
Meek, S.8
Millan, J.9
Cutillas, P.R.10
Smith, A.J.11
Ridley, A.J.12
Ruhrberg, C.13
Gerhardt, H.14
Vanhaesebroeck, B.15
-
40
-
-
0033522927
-
Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
-
Y Fujio and K Walsh (1999) Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 274 16,349-16,354.
-
(1999)
J Biol Chem
, vol.274
, pp. 16,349-16,354
-
-
Fujio, Y.1
Walsh, K.2
-
41
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
S Dimmeler, I Fleming, B Fisslthaler, C Hermann, R Busse and AM Zeiher (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399 601-605.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
42
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
D Fulton, JP Gratton, TJ McCabe, J Fontana, Y Fujio, K Walsh, TF Franke, A Papapetropoulos and WC Sessa (1999) Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399 597-601.
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
Franke, T.F.7
Papapetropoulos, A.8
Sessa, W.C.9
-
43
-
-
30744432102
-
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
-
J Chen, PR Somanath, O Razorenova, WS Chen, N Hay, P Bornstein and TV Byzova (2005) Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med 11 1188-1196.
-
(2005)
Nat Med
, vol.11
, pp. 1188-1196
-
-
Chen, J.1
Somanath, P.R.2
Razorenova, O.3
Chen, W.S.4
Hay, N.5
Bornstein, P.6
Byzova, T.V.7
-
44
-
-
33745646792
-
Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling
-
CC Hong, QP Peterson, JY Hong and RT Peterson (2006) Artery/vein specification is governed by opposing phosphatidylinositol-3 kinase and MAP kinase/ERK signaling. Curr Biol 16 1366-1372.
-
(2006)
Curr Biol
, vol.16
, pp. 1366-1372
-
-
Hong, C.C.1
Peterson, Q.P.2
Hong, J.Y.3
Peterson, R.T.4
-
45
-
-
33750712397
-
MAPping out arteries and veins
-
RE Lamont and S Childs (2006) MAPping out arteries and veins. Sci STKE 2006 pe39.
-
(2006)
Sci STKE
, vol.2006
, pp. pe39
-
-
Lamont, R.E.1
Childs, S.2
-
46
-
-
0037786689
-
Arteries, veins, Notch, and VEGF
-
BM Weinstein and ND Lawson (2002) Arteries, veins, Notch, and VEGF. Cold Spring Harb Symp Quant Biol 67 155-162.
-
(2002)
Cold Spring Harb Symp Quant Biol
, vol.67
, pp. 155-162
-
-
Weinstein, B.M.1
Lawson, N.D.2
-
47
-
-
0842308307
-
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
-
L Lamalice, F Houle, G Jourdan and J Huot (2004) Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38. Oncogene 23 434-435.
-
(2004)
Oncogene
, vol.23
, pp. 434-435
-
-
Lamalice, L.1
Houle, F.2
Jourdan, G.3
Huot, J.4
-
48
-
-
20444385832
-
Activation of p38 has opposing effects on the proliferation and migration of endothelial cells
-
ME McMullen, PW Bryant, CC Glembotski, PA Vincent and KM Pumiglia (2005) Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J Biol Chem 280 20,995-21,003.
-
(2005)
J Biol Chem
, vol.280
, pp. 20,995-21,003
-
-
McMullen, M.E.1
Bryant, P.W.2
Glembotski, C.C.3
Vincent, P.A.4
Pumiglia, K.M.5
-
49
-
-
0030734010
-
p 38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
S Rousseau, F Houle, J Landry and J Huot (1997) p 38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 15 2169-2177.
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, J.3
Huot, J.4
-
50
-
-
0037143447
-
Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis
-
H Habeck, J Odenthal, B Walderich, H Maischein and S Schulte-Merker (2002) Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol 12 1405-1412.
-
(2002)
Curr Biol
, vol.12
, pp. 1405-1412
-
-
Habeck, H.1
Odenthal, J.2
Walderich, B.3
Maischein, H.4
Schulte-Merker, S.5
-
51
-
-
36348994928
-
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish
-
N Bahary, K Goishi, C Stuckenholz, G Weber, J Leblanc, CA Schafer, SS Berman, M Klagsbrun and LI Zon (2007) Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood 110 3627-3636.
-
(2007)
Blood
, vol.110
, pp. 3627-3636
-
-
Bahary, N.1
Goishi, K.2
Stuckenholz, C.3
Weber, G.4
Leblanc, J.5
Schafer, C.A.6
Berman, S.S.7
Klagsbrun, M.8
Zon, L.I.9
-
52
-
-
4344687615
-
The PDGF/VEGF receptor controls blood cell survival in Drosophila
-
K Bruckner, L Kockel, P Duchek, CM Luque, P Rorth and N Perrimon (2004) The PDGF/VEGF receptor controls blood cell survival in Drosophila. Dev Cell 7 73-84.
-
(2004)
Dev Cell
, vol.7
, pp. 73-84
-
-
Bruckner, K.1
Kockel, L.2
Duchek, P.3
Luque, C.M.4
Rorth, P.5
Perrimon, N.6
-
54
-
-
22544486255
-
The complement system in the pathophysiology of pregnancy
-
G Girardi, R Bulla, JE Salmon and F Tedesco (2006) The complement system in the pathophysiology of pregnancy. Mol Immunol 43 68-77.
-
(2006)
Mol Immunol
, vol.43
, pp. 68-77
-
-
Girardi, G.1
Bulla, R.2
Salmon, J.E.3
Tedesco, F.4
-
56
-
-
0032483374
-
Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules
-
N Ito, C Wernstedt, U Engstrom and L Claesson-Welsh (1998) Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules. J Biol Chem 273 23,410-23,418.
-
(1998)
J Biol Chem
, vol.273
, pp. 23,410-23,418
-
-
Ito, N.1
Wernstedt, C.2
Engstrom, U.3
Claesson-Welsh, L.4
-
57
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
GH Fong, J Rossant, M Gertsenstein and ML Breitman (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376 66-70.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
58
-
-
0036530222
-
Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division
-
JB Kearney, CA Ambler, KA Monaco, N Johnson, RG Rapoport and VL Bautch (2002) Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division. Blood 99 2397-2407.
-
(2002)
Blood
, vol.99
, pp. 2397-2407
-
-
Kearney, J.B.1
Ambler, C.A.2
Monaco, K.A.3
Johnson, N.4
Rapoport, R.G.5
Bautch, V.L.6
-
59
-
-
11144297756
-
Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice
-
S Hiratsuka, K Nakao, K Nakamura, M Katsuki, Y Maru and M Shibuya (2005) Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice. Mol Cell Biol 25 346-354.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 346-354
-
-
Hiratsuka, S.1
Nakao, K.2
Nakamura, K.3
Katsuki, M.4
Maru, Y.5
Shibuya, M.6
-
60
-
-
0032482978
-
Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
-
S Hiratsuka, O Minowa, J Kuno, T Noda and M Shibuya (1998) Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA 95 9349-9354.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9349-9354
-
-
Hiratsuka, S.1
Minowa, O.2
Kuno, J.3
Noda, T.4
Shibuya, M.5
-
61
-
-
0035160312
-
Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
D Lyden, K Hattori, S Dias, C Costa, P Blaikie, L Butros, A Chadburn, B Heissig, W Marks, L Witte, Y Wu, D Hicklin, Z Zhu, NR Hackett, RG Crystal, MA Moore, KA Hajjar, K Manova, R Benezra and S Rafii (2001) Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med 7 1194-1201.
-
(2001)
Nat Med
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
Costa, C.4
Blaikie, P.5
Butros, L.6
Chadburn, A.7
Heissig, B.8
Marks, W.9
Witte, L.10
Wu, Y.11
Hicklin, D.12
Zhu, Z.13
Hackett, N.R.14
Crystal, R.G.15
Moore, M.A.16
Hajjar, K.A.17
Manova, K.18
Benezra, R.19
Rafii, S.20
more..
-
62
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
A Luttun, M Tjwa, L Moons, Y Wu, A Angelillo-Scherrer, F Liao, JA Nagy, A Hooper, J Priller, B De Klerck, V Compernolle, E Daci, P Bohlen, M Dewerchin, JM Herbert, R Fava, P Matthys, G Carmeliet, D Collen, HF Dvorak, DJ Hicklin and P Carmeliet (2002) Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 8 831-840.
-
(2002)
Nat Med
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
Wu, Y.4
Angelillo-Scherrer, A.5
Liao, F.6
Nagy, J.A.7
Hooper, A.8
Priller, J.9
De Klerck, B.10
Compernolle, V.11
Daci, E.12
Bohlen, P.13
Dewerchin, M.14
Herbert, J.M.15
Fava, R.16
Matthys, P.17
Carmeliet, G.18
Collen, D.19
Dvorak, H.F.20
Hicklin, D.J.21
Carmeliet, P.22
more..
-
63
-
-
0037703184
-
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
M Autiero, J Waltenberger, D Communi, A Kranz, L Moons, D Lambrechts, J Kroll, S Plaisance, M De Mol, F Bono, S Kliche, G Fellbrich, K Ballmer-Hofer, D Maglione, U Mayr-Beyrle, M Dewerchin, S Dombrowski, D Stanimirovic, P Van Hummelen, C Dehio, DJ Hicklin, G Persico, JM Herbert, M Shibuya, D Collen, EM Conway and P Carmeliet (2003) Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 9 936-943.
-
(2003)
Nat Med
, vol.9
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
Kranz, A.4
Moons, L.5
Lambrechts, D.6
Kroll, J.7
Plaisance, S.8
De Mol, M.9
Bono, F.10
Kliche, S.11
Fellbrich, G.12
Ballmer-Hofer, K.13
Maglione, D.14
Mayr-Beyrle, U.15
Dewerchin, M.16
Dombrowski, S.17
Stanimirovic, D.18
Van Hummelen, P.19
Dehio, C.20
Hicklin, D.J.21
Persico, G.22
Herbert, J.M.23
Shibuya, M.24
Collen, D.25
Conway, E.M.26
Carmeliet, P.27
more..
-
64
-
-
19244379078
-
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
-
P Carmeliet, L Moons, A Luttun, V Vincenti, V Compernolle, M De Mol, Y Wu, F Bono, L Devy, H Beck, D Scholz, T Acker, T DiPalma, M Dewerchin, A Noel, I Stalmans, A Barra, S Blacher, T Vandendriessche, A Ponten, U Eriksson, KH Plate, JM Foidart, W Schaper, DS Charnock-Jones, DJ Hicklin, JM Herbert, D Collen and MG Persico (2001) Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 7 575-583.
-
(2001)
Nat Med
, vol.7
, pp. 575-583
-
-
Carmeliet, P.1
Moons, L.2
Luttun, A.3
Vincenti, V.4
Compernolle, V.5
De Mol, M.6
Wu, Y.7
Bono, F.8
Devy, L.9
Beck, H.10
Scholz, D.11
Acker, T.12
DiPalma, T.13
Dewerchin, M.14
Noel, A.15
Stalmans, I.16
Barra, A.17
Blacher, S.18
Vandendriessche, T.19
Ponten, A.20
Eriksson, U.21
Plate, K.H.22
Foidart, J.M.23
Schaper, W.24
Charnock-Jones, D.S.25
Hicklin, D.J.26
Herbert, J.M.27
Collen, D.28
Persico, M.G.29
more..
-
65
-
-
0035902538
-
Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect
-
K Aase, G von Euler, X Li, A Ponten, P Thoren, R Cao, Y Cao, B Olofsson, S Gebre-Medhin, M Pekny, K Alitalo, C Betsholtz and U Eriksson (2001) Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect. Circulation 104 358-364.
-
(2001)
Circulation
, vol.104
, pp. 358-364
-
-
Aase, K.1
von Euler, G.2
Li, X.3
Ponten, A.4
Thoren, P.5
Cao, R.6
Cao, Y.7
Olofsson, B.8
Gebre-Medhin, S.9
Pekny, M.10
Alitalo, K.11
Betsholtz, C.12
Eriksson, U.13
-
66
-
-
2942668041
-
Lymphatic vasculature: Development, molecular regulation and role in tumor metastasis and inflammation
-
P Saharinen, T Tammela, MJ Karkkainen and K Alitalo (2004) Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends Immunol 25 387-395.
-
(2004)
Trends Immunol
, vol.25
, pp. 387-395
-
-
Saharinen, P.1
Tammela, T.2
Karkkainen, M.J.3
Alitalo, K.4
-
68
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
DJ Dumont, L Jussila, J Taipale, A Lymboussaki, T Mustonen, K Pajusola, M Breitman and K Alitalo (1998) Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 282 946-949.
-
(1998)
Science
, vol.282
, pp. 946-949
-
-
Dumont, D.J.1
Jussila, L.2
Taipale, J.3
Lymboussaki, A.4
Mustonen, T.5
Pajusola, K.6
Breitman, M.7
Alitalo, K.8
-
69
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
MJ Karkkainen, P Haiko, K Sainio, J Partanen, J Taipale, TV Petrova, M Jeltsch, DG Jackson, M Talikka, H Rauvala, C Betsholtz and K Alitalo (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol 5 74-80.
-
(2004)
Nat Immunol
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
Betsholtz, C.11
Alitalo, K.12
-
70
-
-
33744996035
-
Development of the zebrafish lymphatic system requires VEGFC signaling
-
AM Kuchler, E Gjini, J Peterson-Maduro, B Cancilla, H Wolburg and S Schulte-Merker (2006) Development of the zebrafish lymphatic system requires VEGFC signaling. Curr Biol 16 1244-1248.
-
(2006)
Curr Biol
, vol.16
, pp. 1244-1248
-
-
Kuchler, A.M.1
Gjini, E.2
Peterson-Maduro, J.3
Cancilla, B.4
Wolburg, H.5
Schulte-Merker, S.6
-
71
-
-
13844273017
-
Vascular endothelial growth factor D is dispensable for development of the lymphatic system
-
ME Baldwin, MM Halford, S Roufail, RA Williams, ML Hibbs, D Grail, H Kubo, SA Stacker and MG Achen (2005) Vascular endothelial growth factor D is dispensable for development of the lymphatic system. Mol Cell Biol 25 2441-2449.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2441-2449
-
-
Baldwin, M.E.1
Halford, M.M.2
Roufail, S.3
Williams, R.A.4
Hibbs, M.L.5
Grail, D.6
Kubo, H.7
Stacker, S.A.8
Achen, M.G.9
-
72
-
-
34248213771
-
A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis
-
M Song, H Yang, S Yao, F Ma, Z Li, Y Deng, H Deng, Q Zhou, S Lin and Y Wei (2007) A critical role of vascular endothelial growth factor D in zebrafish embryonic vasculogenesis and angiogenesis. Biochem Biophys Res Commun 357 924-930.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 924-930
-
-
Song, M.1
Yang, H.2
Yao, S.3
Ma, F.4
Li, Z.5
Deng, Y.6
Deng, H.7
Zhou, Q.8
Lin, S.9
Wei, Y.10
-
73
-
-
85147070893
-
-
Blood 2008
-
Ny A, Koch M, Vandevelde W, Schneider M, Fischer C, Diez-Juan A, Neven E, Geudens I, Maity S, Moons L, Plaisance S, Lambrechts D, Carmeliet P, Dewerchin M. Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles. Blood 2008.
-
Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.
-
-
Ny, A.1
Koch, M.2
Vandevelde, W.3
Schneider, M.4
Fischer, C.5
Diez-Juan, A.6
Neven, E.7
Geudens, I.8
Maity, S.9
Moons, L.10
Plaisance, S.11
Lambrechts, D.12
Carmeliet, P.13
Dewerchin, M.14
-
74
-
-
0033862310
-
Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
-
A Irrthum, MJ Karkkainen, K Devriendt, K Alitalo and M Vikkula (2000) Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Am J Hum Genet 67 295-301.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 295-301
-
-
Irrthum, A.1
Karkkainen, M.J.2
Devriendt, K.3
Alitalo, K.4
Vikkula, M.5
-
75
-
-
0035997376
-
Order out of chaos: Assembly of ligand binding sites in heparan sulfate
-
JD Esko and SB Selleck (2002) Order out of chaos: assembly of ligand binding sites in heparan sulfate. Annu Rev Biochem 71 435-471.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 435-471
-
-
Esko, J.D.1
Selleck, S.B.2
-
76
-
-
0342547239
-
Identification of a heparin binding peptide on the extracellular domain of the KDR VEGF receptor
-
AM Dougher, H Wasserstrom, L Torley, L Shridaran, P Westdock, RE Hileman, JR Fromm, R Anderberg, S Lyman, RJ Linhardt, J Kaplan and BI Terman (1997) Identification of a heparin binding peptide on the extracellular domain of the KDR VEGF receptor. Growth Factors 14 257-268.
-
(1997)
Growth Factors
, vol.14
, pp. 257-268
-
-
Dougher, A.M.1
Wasserstrom, H.2
Torley, L.3
Shridaran, L.4
Westdock, P.5
Hileman, R.E.6
Fromm, J.R.7
Anderberg, R.8
Lyman, S.9
Linhardt, R.J.10
Kaplan, J.11
Terman, B.I.12
-
77
-
-
33646076452
-
Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis
-
L Jakobsson, J Kreuger, K Holmborn, L Lundin, I Eriksson, L Kjellen and L Claesson-Welsh (2006) Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis. Dev Cell 10 625-634.
-
(2006)
Dev Cell
, vol.10
, pp. 625-634
-
-
Jakobsson, L.1
Kreuger, J.2
Holmborn, K.3
Lundin, L.4
Eriksson, I.5
Kjellen, L.6
Claesson-Welsh, L.7
-
78
-
-
0030730838
-
Roles of a neuronal cell-surface molecule, neuropilin, in nerve fiber fasciculation and guidance
-
H Fujisawa, T Kitsukawa, A Kawakami, S Takagi, M Shimizu and T Hirata (1997) Roles of a neuronal cell-surface molecule, neuropilin, in nerve fiber fasciculation and guidance. Cell Tissue Res 290 465-470.
-
(1997)
Cell Tissue Res
, vol.290
, pp. 465-470
-
-
Fujisawa, H.1
Kitsukawa, T.2
Kawakami, A.3
Takagi, S.4
Shimizu, M.5
Hirata, T.6
-
79
-
-
0030829388
-
Neuropilin is a semaphorin III receptor
-
AL Kolodkin, DV Levengood, EG Rowe, YT Tai, RJ Giger and DD Ginty (1997) Neuropilin is a semaphorin III receptor. Cell 90 753-762.
-
(1997)
Cell
, vol.90
, pp. 753-762
-
-
Kolodkin, A.L.1
Levengood, D.V.2
Rowe, E.G.3
Tai, Y.T.4
Giger, R.J.5
Ginty, D.D.6
-
80
-
-
0030847193
-
Neuropilin is a receptor for the axonal chemorepellent Semaphorin III
-
Z He and M Tessier-Lavigne (1997) Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90 739-751.
-
(1997)
Cell
, vol.90
, pp. 739-751
-
-
He, Z.1
Tessier-Lavigne, M.2
-
81
-
-
0032549799
-
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
-
S Soker, S Takashima, HQ Miao, G Neufeld and M Klagsbrun (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92 735-745.
-
(1998)
Cell
, vol.92
, pp. 735-745
-
-
Soker, S.1
Takashima, S.2
Miao, H.Q.3
Neufeld, G.4
Klagsbrun, M.5
-
82
-
-
33746320397
-
Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling
-
Y Shintani, S Takashima, Y Asano, H Kato, Y Liao, S Yamazaki, O Tsukamoto, O Seguchi, H Yamamoto, T Fukushima, K Sugahara, M Kitakaze and M Hori (2006) Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling. Embo J 25 3045-3055.
-
(2006)
Embo J
, vol.25
, pp. 3045-3055
-
-
Shintani, Y.1
Takashima, S.2
Asano, Y.3
Kato, H.4
Liao, Y.5
Yamazaki, S.6
Tsukamoto, O.7
Seguchi, O.8
Yamamoto, H.9
Fukushima, T.10
Sugahara, K.11
Kitakaze, M.12
Hori, M.13
-
83
-
-
33746503288
-
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors
-
T Karpanen, CA Heckman, S Keskitalo, M Jeltsch, H Ollila, G Neufeld, L Tamagnone and K Alitalo (2006) Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J 20 1462-1472.
-
(2006)
FASEB J
, vol.20
, pp. 1462-1472
-
-
Karpanen, T.1
Heckman, C.A.2
Keskitalo, S.3
Jeltsch, M.4
Ollila, H.5
Neufeld, G.6
Tamagnone, L.7
Alitalo, K.8
-
84
-
-
0032707249
-
A requirement for neuropilin-1 in embryonic vessel formation
-
T Kawasaki, T Kitsukawa, Y Bekku, Y Matsuda, M Sanbo, T Yagi and H Fujisawa (1999) A requirement for neuropilin-1 in embryonic vessel formation. Development 126 4895-4902.
-
(1999)
Development
, vol.126
, pp. 4895-4902
-
-
Kawasaki, T.1
Kitsukawa, T.2
Bekku, Y.3
Matsuda, Y.4
Sanbo, M.5
Yagi, T.6
Fujisawa, H.7
-
85
-
-
0030778454
-
Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice
-
T Kitsukawa, M Shimizu, M Sanbo, T Hirata, M Taniguchi, Y Bekku, T Yagi and H Fujisawa (1997) Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice. Neuron 19 995-1005.
-
(1997)
Neuron
, vol.19
, pp. 995-1005
-
-
Kitsukawa, T.1
Shimizu, M.2
Sanbo, M.3
Hirata, T.4
Taniguchi, M.5
Bekku, Y.6
Yagi, T.7
Fujisawa, H.8
-
86
-
-
0029562097
-
Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs
-
T Kitsukawa, A Shimono, A Kawakami, H Kondoh and H Fujisawa (1995) Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development 121 4309-4318.
-
(1995)
Development
, vol.121
, pp. 4309-4318
-
-
Kitsukawa, T.1
Shimono, A.2
Kawakami, A.3
Kondoh, H.4
Fujisawa, H.5
-
87
-
-
0034065239
-
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
-
RJ Giger, JF Cloutier, A Sahay, RK Prinjha, DV Levengood, SE Moore, S Pickering, D Simmons, S Rastan, FS Walsh, AL Kolodkin, DD Ginty and M Geppert (2000) Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron 25 29-41.
-
(2000)
Neuron
, vol.25
, pp. 29-41
-
-
Giger, R.J.1
Cloutier, J.F.2
Sahay, A.3
Prinjha, R.K.4
Levengood, D.V.5
Moore, S.E.6
Pickering, S.7
Simmons, D.8
Rastan, S.9
Walsh, F.S.10
Kolodkin, A.L.11
Ginty, D.D.12
Geppert, M.13
-
88
-
-
0034023548
-
Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections
-
H Chen, A Bagri, JA Zupicich, Y Zou, E Stoeckli, SJ Pleasure, DH Lowenstein, WC Skarnes, A Chedotal and M Tessier-Lavigne (2000) Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 25 43-56.
-
(2000)
Neuron
, vol.25
, pp. 43-56
-
-
Chen, H.1
Bagri, A.2
Zupicich, J.A.3
Zou, Y.4
Stoeckli, E.5
Pleasure, S.J.6
Lowenstein, D.H.7
Skarnes, W.C.8
Chedotal, A.9
Tessier-Lavigne, M.10
-
89
-
-
0036803751
-
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
-
L Yuan, D Moyon, L Pardanaud, C Breant, MJ Karkkainen, K Alitalo and A Eichmann (2002) Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development 129 4797-4806.
-
(2002)
Development
, vol.129
, pp. 4797-4806
-
-
Yuan, L.1
Moyon, D.2
Pardanaud, L.3
Breant, C.4
Karkkainen, M.J.5
Alitalo, K.6
Eichmann, A.7
-
90
-
-
0037133617
-
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis
-
S Takashima, M Kitakaze, M Asakura, H Asanuma, S Sanada, F Tashiro, H Niwa, J Miyazaki Ji, S Hirota, Y Kitamura, T Kitsukawa, H Fujisawa, M Klagsbrun and M Hori (2002) Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci USA 99 3657-3662.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3657-3662
-
-
Takashima, S.1
Kitakaze, M.2
Asakura, M.3
Asanuma, H.4
Sanada, S.5
Tashiro, F.6
Niwa, H.7
Miyazaki Ji, J.8
Hirota, S.9
Kitamura, Y.10
Kitsukawa, T.11
Fujisawa, H.12
Klagsbrun, M.13
Hori, M.14
-
91
-
-
0038686623
-
Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
-
C Gu, ER Rodriguez, DV Reimert, T Shu, B Fritzsch, LJ Richards, AL Kolodkin and DD Ginty (2003) Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell 5 45-57.
-
(2003)
Dev Cell
, vol.5
, pp. 45-57
-
-
Gu, C.1
Rodriguez, E.R.2
Reimert, D.V.3
Shu, T.4
Fritzsch, B.5
Richards, L.J.6
Kolodkin, A.L.7
Ginty, D.D.8
-
92
-
-
2942585626
-
Cloning and embryonic expression of zebrafish neuropilin genes
-
HH Yu, C Houart and CB Moens (2004) Cloning and embryonic expression of zebrafish neuropilin genes. Gene Expr Patterns 4 371-378.
-
(2004)
Gene Expr Patterns
, vol.4
, pp. 371-378
-
-
Yu, H.H.1
Houart, C.2
Moens, C.B.3
-
93
-
-
0036678171
-
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish
-
P Lee, K Goishi, AJ Davidson, R Mannix, L Zon and M Klagsbrun (2002) Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish. Proc Natl Acad Sci USA 99 10,470-10,475.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10,470-10,475
-
-
Lee, P.1
Goishi, K.2
Davidson, A.J.3
Mannix, R.4
Zon, L.5
Klagsbrun, M.6
-
94
-
-
34249650761
-
The role of junctional adhesion molecules in vascular inflammation
-
C Weber, L Fraemohs and E Dejana (2007) The role of junctional adhesion molecules in vascular inflammation. Nat Rev Immunol 7 467-477.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 467-477
-
-
Weber, C.1
Fraemohs, L.2
Dejana, E.3
-
95
-
-
0033597718
-
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
-
P Carmeliet, MG Lampugnani, L Moons, F Breviario, V Compernolle, F Bono, G Balconi, R Spagnuolo, B Oostuyse, M Dewerchin, A Zanetti, A Angellilo, V Mattot, D Nuyens, E Lutgens, F Clotman, MC de Ruiter, A Gittenberger-de Groot, R Poelmann, F Lupu, JM Herbert, D Collen and E Dejana (1999) Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 98 147-157.
-
(1999)
Cell
, vol.98
, pp. 147-157
-
-
Carmeliet, P.1
Lampugnani, M.G.2
Moons, L.3
Breviario, F.4
Compernolle, V.5
Bono, F.6
Balconi, G.7
Spagnuolo, R.8
Oostuyse, B.9
Dewerchin, M.10
Zanetti, A.11
Angellilo, A.12
Mattot, V.13
Nuyens, D.14
Lutgens, E.15
Clotman, F.16
de Ruiter, M.C.17
Gittenberger-de Groot, A.18
Poelmann, R.19
Lupu, F.20
Herbert, J.M.21
Collen, D.22
Dejana, E.23
more..
-
96
-
-
18844473540
-
Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia
-
D Bellomo, JP Headrick, GU Silins, CA Paterson, PS Thomas, M Gartside, A Mould, MM Cahill, ID Tonks, SM Grimmond, S Townson, C Wells, M Little, MC Cummings, NK Hayward and GF Kay (2000) Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circ Res 86 E29-E35.
-
(2000)
Circ Res
, vol.86
, pp. E29-E35
-
-
Bellomo, D.1
Headrick, J.P.2
Silins, G.U.3
Paterson, C.A.4
Thomas, P.S.5
Gartside, M.6
Mould, A.7
Cahill, M.M.8
Tonks, I.D.9
Grimmond, S.M.10
Townson, S.11
Wells, C.12
Little, M.13
Cummings, M.C.14
Hayward, N.K.15
Kay, G.F.16
-
97
-
-
0032764427
-
Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
-
GH Fong, L Zhang, DM Bryce and J Peng (1999) Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development 126 3015-3025.
-
(1999)
Development
, vol.126
, pp. 3015-3025
-
-
Fong, G.H.1
Zhang, L.2
Bryce, D.M.3
Peng, J.4
-
98
-
-
0035114105
-
Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis
-
S Hiratsuka, Y Maru, A Okada, M Seiki, T Noda and M Shibuya (2001) Involvement of Flt-1 tyrosine kinase (vascular endothelial growth factor receptor-1) in pathological angiogenesis. Cancer Res 61 1207-1213.
-
(2001)
Cancer Res
, vol.61
, pp. 1207-1213
-
-
Hiratsuka, S.1
Maru, Y.2
Okada, A.3
Seiki, M.4
Noda, T.5
Shibuya, M.6
|