Crystal structures of novel Vascular Endothelial Growth Factors (VEGF) from snake venoms: Insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1

Journal of Biological Chemistry

Volumn 280, Issue 3, 2005, Pages 2126-2131

  Suto, Kyoko ^a,c   Yamazaki, Yasuo ^b   Morita, Takashi ^b   Mizuno, Hiroshi ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^c NEC CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE;

RECEPTOR BINDING; SNAKE VENOM; SURFACE POTENTIAL; VASCULAR ENDOTHELIAL GROWTH FACTORS (VEGF);

ENZYMES;

PLACENTAL GROWTH FACTOR; SNAKE VENOM; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN VAMMIN; VASCULOTROPIN VR 1;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR BINDING; SEQUENCE ALIGNMENT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; SEQUENCE HOMOLOGY, AMINO ACID; SNAKE VENOMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

INSERTION SEQUENCES; SERPENTES;

EID: 12544258730     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411395200     Document Type: Article

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