메뉴 건너뛰기




Volumn 19, Issue 1, 2013, Pages 170-182

MFG-E8 and HMGB1 are involved in the mechanism underlying alcohol-induced impairment of macrophage efferocytosis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALCOHOL; HIGH MOBILITY GROUP B1 PROTEIN; HYDROGEN PEROXIDE; LACTADHERIN; REACTIVE OXYGEN METABOLITE; RECOMBINANT LACTADHERIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 84882793018     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2012.00260     Document Type: Article
Times cited : (32)

References (51)
  • 1
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • Fadok VA, et al. (1992) Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:2207-16.
    • (1992) J. Immunol , vol.148 , pp. 2207-2216
    • Fadok, V.A.1
  • 3
    • 78249253033 scopus 로고    scopus 로고
    • Secondary necrosis: The natural outcome of the complete apoptotic program
    • Silva MT. (2010) Secondary necrosis: the natural outcome of the complete apoptotic program. FEBS Lett. 584:4491-9.
    • (2010) FEBS Lett , vol.584 , pp. 4491-4499
    • Silva, M.T.1
  • 4
    • 0031454570 scopus 로고    scopus 로고
    • Immunosuppressive effects of apoptotic cells
    • Voll RE, et al. (1997) Immunosuppressive effects of apoptotic cells. Nature. 390:350-1.
    • (1997) Nature , vol.390 , pp. 350-351
    • Voll, R.E.1
  • 5
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFbeta, PGE2, and PAF
    • Fadok VA, et al. (1998) Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFbeta, PGE2, and PAF. J. Clin. Invest. 101:890-8.
    • (1998) J. Clin. Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1
  • 7
    • 77956255766 scopus 로고    scopus 로고
    • Find-me and eat-me signals in apoptotic cell clearance: Progress and conundrums
    • Ravichandran KS. (2010) Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums. J. Exp. Med. 207:1807-17.
    • (2010) J. Exp. Med , vol.207 , pp. 1807-1817
    • Ravichandran, K.S.1
  • 8
    • 65349145485 scopus 로고    scopus 로고
    • Overexpression of aldehyde dehydrogenase-2 attenuates chronic alcohol exposure-induced apoptosis, change in Akt and Pim signalling in liver
    • Guo R, Zhong L, Ren J. (2009) Overexpression of aldehyde dehydrogenase-2 attenuates chronic alcohol exposure-induced apoptosis, change in Akt and Pim signalling in liver. Clin. Exp. Pharmacol. Physiol. 36:463-8.
    • (2009) Clin. Exp. Pharmacol. Physiol , vol.36 , pp. 463-468
    • Guo, R.1    Zhong, L.2    Ren, J.3
  • 9
    • 77949375831 scopus 로고    scopus 로고
    • Acute alcohol exposure induces apoptosis and increases histone H3K9/18 acetylation in the mid-gestation mouse lung
    • Wang X, Gomutputra P, Wolgemuth DJ, Baxi LV. (2010) Acute alcohol exposure induces apoptosis and increases histone H3K9/18 acetylation in the mid-gestation mouse lung. Reprod. Sci. 17:384-90.
    • (2010) Reprod. Sci , vol.17 , pp. 384-390
    • Wang, X.1    Gomutputra, P.2    Wolgemuth, D.J.3    Baxi, L.V.4
  • 10
    • 84859620774 scopus 로고    scopus 로고
    • Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner
    • Tan Y, et al. (2012) Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner. J. Am. Coll. Cardiol. 59:1477-86.
    • (2012) J. Am. Coll. Cardiol , vol.59 , pp. 1477-1486
    • Tan, Y.1
  • 11
    • 44649164968 scopus 로고    scopus 로고
    • Exposuredependent effects of ethanol on the innate immune system
    • Goral J, Karavitis J, Kovacs EJ. (2008) Exposuredependent effects of ethanol on the innate immune system. Alcohol. 42:237-47.
    • (2008) Alcohol , vol.42 , pp. 237-247
    • Goral, J.1    Karavitis, J.2    Kovacs, E.J.3
  • 12
    • 82555193831 scopus 로고    scopus 로고
    • Macrophage phagocytosis: Effects of environmental pollutants, alcohol, cigarette smoke, and other external factors
    • Karavitis J, Kovacs EJ. (2011) Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factors. J. Leukoc. Biol. 90:1065-78.
    • (2011) J. Leukoc. Biol , vol.90 , pp. 1065-1078
    • Karavitis, J.1    Kovacs, E.J.2
  • 13
    • 77957377109 scopus 로고    scopus 로고
    • Acute and chronic alcohol exposure impair the phagocytosis of apoptotic cells and enhance the pulmonary inflammatory response
    • Boé DM, et al. (2010) Acute and chronic alcohol exposure impair the phagocytosis of apoptotic cells and enhance the pulmonary inflammatory response. Alcohol Clin. Exp. Res. 34:1723-32.
    • (2010) Alcohol Clin. Exp. Res , vol.34 , pp. 1723-1732
    • Boé, D.M.1
  • 14
    • 66149128052 scopus 로고    scopus 로고
    • SED1/MFG-E8: A Bi-Motif protein that orchestrates diverse cellular interactions
    • Raymond A, Ensslin MA, Shur BD. (2009) SED1/MFG-E8: A Bi-Motif protein that orchestrates diverse cellular interactions. J. Cell Biochem. 106:957-66.
    • (2009) J. Cell Biochem , vol.106 , pp. 957-966
    • Raymond, A.1    Ensslin, M.A.2    Shur, B.D.3
  • 15
    • 0037046580 scopus 로고    scopus 로고
    • Identification of a factor that links apoptotic cells to phagocytes
    • Hanayama R, et al. (2002) Identification of a factor that links apoptotic cells to phagocytes. Nature. 417:182-7.
    • (2002) Nature , vol.417 , pp. 182-187
    • Hanayama, R.1
  • 16
    • 2442665179 scopus 로고    scopus 로고
    • Autoimmune disease and impaired uptake of apoptotic cells in MFGE8-deficient mice
    • Hanayama R, et al. (2004) Autoimmune disease and impaired uptake of apoptotic cells in MFGE8-deficient mice. Science. 304:1147-50.
    • (2004) Science , vol.304 , pp. 1147-1150
    • Hanayama, R.1
  • 17
    • 36849003113 scopus 로고    scopus 로고
    • Milk fat globule-EGF factor 8/ lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium
    • Bu HF, et al. (2007) Milk fat globule-EGF factor 8/ lactadherin plays a crucial role in maintenance and repair of murine intestinal epithelium. J. Clin. Invest. 117:3673-83.
    • (2007) J. Clin. Invest , vol.117 , pp. 3673-3683
    • Bu, H.F.1
  • 18
    • 77956020997 scopus 로고    scopus 로고
    • Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats
    • Wu R, et al. (2010) Milk fat globule EGF factor 8 attenuates sepsis-induced apoptosis and organ injury in alcohol-intoxicated rats. Alcohol. Clin. Exp. Res. 34:1625-33.
    • (2010) Alcohol. Clin. Exp. Res , vol.34 , pp. 1625-1633
    • Wu, R.1
  • 19
    • 67449164310 scopus 로고    scopus 로고
    • MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent alphavbeta3 integrin signaling
    • Aziz MM, et al. (2009) MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent alphavbeta3 integrin signaling. J. Immunol. 182:7222-32.
    • (2009) J. Immunol , vol.182 , pp. 7222-7232
    • Aziz, M.M.1
  • 20
    • 72849117761 scopus 로고    scopus 로고
    • Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages
    • Atabai K, et al. (2009) Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J. Clin. Invest. 119:3713-22.
    • (2009) J. Clin. Invest , vol.119 , pp. 3713-3722
    • Atabai, K.1
  • 21
    • 76749155867 scopus 로고    scopus 로고
    • MFG-E8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion
    • Cui T, et al. (2009) MFG-E8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion. Am. J. Respir. Crit. Care Med. 181:238-46
    • (2009) Am. J. Respir. Crit. Care Med , vol.181 , pp. 238-246
    • Cui, T.1
  • 22
    • 33745587596 scopus 로고    scopus 로고
    • Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis
    • Miksa M, et al. (2006) Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis. Shock. 25:586-93.
    • (2006) Shock , vol.25 , pp. 586-593
    • Miksa, M.1
  • 23
    • 79957952612 scopus 로고    scopus 로고
    • Milk fat globule-EGF factor 8 is a critical protein for healing of dextran sodium sulfate-induced acute colitis in mice
    • Chogle A, et al. (2011) Milk fat globule-EGF factor 8 is a critical protein for healing of dextran sodium sulfate-induced acute colitis in mice. Mol. Med. 17:502-7.
    • (2011) Mol. Med , vol.17 , pp. 502-507
    • Chogle, A.1
  • 24
    • 56049106702 scopus 로고    scopus 로고
    • High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine
    • Liu G, et al. (2008) High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine. J. Immunol. 181:4240-6.
    • (2008) J. Immunol , vol.181 , pp. 4240-4246
    • Liu, G.1
  • 25
    • 34249930707 scopus 로고    scopus 로고
    • Establishment of immortalized rat Kupffer cell lines
    • Peng Y, Murr MM. (2007) Establishment of immortalized rat Kupffer cell lines. Cytokine. 37:185-91.
    • (2007) Cytokine , vol.37 , pp. 185-191
    • Peng, Y.1    Murr, M.M.2
  • 26
    • 16644376635 scopus 로고    scopus 로고
    • Isolation and culture of murine macrophages
    • Davies JQ, Gordon S. (2005) Isolation and culture of murine macrophages. Methods Mol. Biol. 290:91-103.
    • (2005) Methods Mol. Biol , vol.290 , pp. 91-103
    • Davies, J.Q.1    Gordon, S.2
  • 27
    • 0016064888 scopus 로고
    • In vitro synthesis and secretion of lysozyme by mononuclear phagocytes
    • Gordon S, Todd J, Cohn ZA. (1974) In vitro synthesis and secretion of lysozyme by mononuclear phagocytes. J. Exp. Med. 139:1228-48.
    • (1974) J. Exp. Med , vol.139 , pp. 1228-1248
    • Gordon, S.1    Todd, J.2    Cohn, Z.A.3
  • 28
    • 33845391183 scopus 로고    scopus 로고
    • Lysozyme-modified probiotic components protect rats against polymicrobial sepsis: Role of macrophages and cathelicidin-related innate immunity
    • Bu HF, et al. (2006) Lysozyme-modified probiotic components protect rats against polymicrobial sepsis: role of macrophages and cathelicidin-related innate immunity. J. Immunol. 177:8767-76.
    • (2006) J. Immunol , vol.177 , pp. 8767-8776
    • Bu, H.F.1
  • 29
    • 84934439382 scopus 로고    scopus 로고
    • Human monocytes, macrophages, and dendritic cells: Alcohol treatment methods
    • Szabo G, Mandrekar P. (2008) Human monocytes, macrophages, and dendritic cells: alcohol treatment methods. Methods Mol. Biol. 447:113-24.
    • (2008) Methods Mol. Biol , vol.447 , pp. 113-124
    • Szabo, G.1    Mandrekar, P.2
  • 30
    • 65649143785 scopus 로고    scopus 로고
    • In vitro and in vivo models of acute alcohol exposure
    • Dolganiuc A, Szabo G. (2009) In vitro and in vivo models of acute alcohol exposure. World J. Gastroenterol. 15:1168-77.
    • (2009) World J. Gastroenterol , vol.15 , pp. 1168-1177
    • Dolganiuc, A.1    Szabo, G.2
  • 31
    • 70249091176 scopus 로고    scopus 로고
    • The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes
    • Mandrekar P, Bala S, Catalano D, Kodys K, Szabo G. (2009) The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. J. Immunol. 183:1320-7.
    • (2009) J. Immunol , vol.183 , pp. 1320-1327
    • Mandrekar, P.1    Bala, S.2    Catalano, D.3    Kodys, K.4    Szabo, G.5
  • 32
    • 0034327754 scopus 로고    scopus 로고
    • An early oxygendependent step is required for dexamethasoneinduced apoptosis of immature mouse thymocytes
    • Torres-Roca JF, et al. (2000) An early oxygendependent step is required for dexamethasoneinduced apoptosis of immature mouse thymocytes. J. Immunol. 165:4822-30.
    • (2000) J. Immunol , vol.165 , pp. 4822-4830
    • Torres-Roca, J.F.1
  • 33
    • 65549164302 scopus 로고    scopus 로고
    • Milk fat globule-EGF factor 8 mRNA expression in rat splanchnic tissues during postnatal development
    • Wang X, Bu HF, De Plaen IG, Tan XD. (2009) Milk fat globule-EGF factor 8 mRNA expression in rat splanchnic tissues during postnatal development. Intl. J. Clin. Exp. Med. 2:36-40.
    • (2009) Intl. J. Clin. Exp. Med , vol.2 , pp. 36-40
    • Wang, X.1    Bu, H.F.2    de Plaen, I.G.3    Tan, X.D.4
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method
    • Livak KJ, Schmittgen TD. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods. 25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 0030584901 scopus 로고    scopus 로고
    • Platelet-activating factor and endotoxin increase the enzyme activity and gene expression of type II phospholipase A2 in the rat intestine: Role of polymorphonuclear leukocytes
    • Tan XD, et al. (1996) Platelet-activating factor and endotoxin increase the enzyme activity and gene expression of type II phospholipase A2 in the rat intestine: Role of polymorphonuclear leukocytes. J. Immunol. 156:2985-90.
    • (1996) J. Immunol , vol.156 , pp. 2985-2990
    • Tan, X.D.1
  • 36
    • 84863151358 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice
    • Sun X, et al. (2012) Activation of peroxisome proliferator-activated receptor-gamma by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice. Am. J. Physiol. Gastrointest. Liver Physiol. 302:G548-57.
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol , vol.302
    • Sun, X.1
  • 37
    • 1642463814 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant defenses in ethanol-induced cell injury
    • Koch OR, et al. (2004) Oxidative stress and antioxidant defenses in ethanol-induced cell injury. Mol. Aspects Med. 25:191-8.
    • (2004) Mol. Aspects Med , vol.25 , pp. 191-198
    • Koch, O.R.1
  • 38
    • 33746601126 scopus 로고    scopus 로고
    • Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages
    • Powers KA, et al. (2006) Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. J. Exp. Med. 203:1951-61.
    • (2006) J. Exp. Med , vol.203 , pp. 1951-1961
    • Powers, K.A.1
  • 39
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • Andersson U, Tracey KJ. (2011) HMGB1 is a therapeutic target for sterile inflammation and infection. Annu. Rev. Immunol. 29:139-62.
    • (2011) Annu. Rev. Immunol , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 40
    • 77954396042 scopus 로고    scopus 로고
    • Clearance of apoptotic cells: Implications in health and disease
    • Elliott MR, Ravichandran KS. (2010) Clearance of apoptotic cells: implications in health and disease. J. Cell Biol. 189:1059-70.
    • (2010) J. Cell Biol , vol.189 , pp. 1059-1070
    • Elliott, M.R.1    Ravichandran, K.S.2
  • 41
    • 78649673357 scopus 로고    scopus 로고
    • HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin
    • Friggeri A, et al. (2010) HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin. Am. J. Physiol. Cell Physiol. 299:C1267-76.
    • (2010) Am. J. Physiol. Cell Physiol , vol.299
    • Friggeri, A.1
  • 42
    • 36849080928 scopus 로고    scopus 로고
    • Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages
    • Miksa M, Amin D, Wu R, Ravikumar TS, Wang P. (2007) Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages. Mol. Med. 13:553-60.
    • (2007) Mol. Med , vol.13 , pp. 553-560
    • Miksa, M.1    Amin, D.2    Wu, R.3    Ravikumar, T.S.4    Wang, P.5
  • 43
    • 84873530432 scopus 로고    scopus 로고
    • Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells
    • Liu Y, et al. (2013) Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells. PLoS. ONE. 8:e55754.
    • (2013) PLoS. ONE , vol.8
    • Liu, Y.1
  • 44
    • 59849099434 scopus 로고    scopus 로고
    • Milk fat globule epidermal growth factorfactor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway
    • Komura H, Miksa M, Wu R, Goyert SM, Wang P. (2009) Milk fat globule epidermal growth factorfactor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway. J. Immunol. 182:581-7.
    • (2009) J. Immunol , vol.182 , pp. 581-587
    • Komura, H.1    Miksa, M.2    Wu, R.3    Goyert, S.M.4    Wang, P.5
  • 45
    • 35748967851 scopus 로고    scopus 로고
    • High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity
    • Bianchi ME, Manfredi AA. (2007) High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol. Rev. 220:35-46.
    • (2007) Immunol. Rev , vol.220 , pp. 35-46
    • Bianchi, M.E.1    Manfredi, A.A.2
  • 46
    • 80555149745 scopus 로고    scopus 로고
    • Intracellular HMGB1 negatively regulates efferocytosis
    • Banerjee S, et al. (2011) Intracellular HMGB1 negatively regulates efferocytosis. J. Immunol. 187:4686-94.
    • (2011) J. Immunol , vol.187 , pp. 4686-4694
    • Banerjee, S.1
  • 47
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. (2005) Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5:953-64.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 48
    • 80053314254 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice
    • Louvet A, et al. (2011) Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice. Hepatology. 54:1217-26.
    • (2011) Hepatology , vol.54 , pp. 1217-1226
    • Louvet, A.1
  • 49
    • 0024521083 scopus 로고
    • Alcohol suppresses lipopolysaccharide-induced tumor necrosis factor activity in serum and lung
    • Nelson S, Bagby G, Summer WR. (1989) Alcohol suppresses lipopolysaccharide-induced tumor necrosis factor activity in serum and lung. Life Sci. 44:673-76.
    • (1989) Life Sci , vol.44 , pp. 673-676
    • Nelson, S.1    Bagby, G.2    Summer, W.R.3
  • 50
    • 0029787963 scopus 로고    scopus 로고
    • Regulation of human monocyte functions by acute ethanol treatment: Decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production
    • Szabo G, Mandrekar P, Girouard L, Catalano D. (1996) Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production. Alcohol. Clin. Exp. Res. 20:900-7.
    • (1996) Alcohol. Clin. Exp. Res , vol.20 , pp. 900-907
    • Szabo, G.1    Mandrekar, P.2    Girouard, L.3    Catalano, D.4
  • 51
    • 0026211909 scopus 로고
    • Tumor necrosis and alcoholic hepatitis
    • McClain CJ. (1991) Tumor necrosis and alcoholic hepatitis. Hepatology. 14:394-6.
    • (1991) Hepatology , vol.14 , pp. 394-396
    • McClain, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.