Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages

Journal of Clinical Investigation

Volumn 119, Issue 12, 2009, Pages 3713-3722

  Atabai, Kamran ^a   Jame, Sina ^a   Azhar, Nabil ^a   Kuo, Alex ^a   Lam, Michael ^a   McKleroy, William ^a   DeHart, Greg ^a   Rahman, Salman ^a   Xia, Dee Dee ^a   Melton, Andrew C ^a   Wolters, Paul ^a   Emson, Claire L ^b   Turner, Scott M ^b   Werb, Zena ^a   Sheppard, Dean ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KINEMED INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN; DISCOIDIN; GLYCOPROTEIN; LACTADHERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COLLAGEN METABOLISM; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; EXTRACELLULAR MATRIX; INFLAMMATION; LUNG FIBROSIS; LUNG INJURY; MACROPHAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TARGETING;

ANIMALS; ANTIGENS, SURFACE; APOPTOSIS; BASE SEQUENCE; BLEOMYCIN; COLLAGEN; DISEASE MODELS, ANIMAL; DNA PRIMERS; EXTRACELLULAR MATRIX; FEMALE; LECTINS; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, KNOCKOUT; MILK PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; PULMONARY FIBROSIS; RECOMBINANT PROTEINS;

EID: 72849117761     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI40053     Document Type: Article

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