Overexpression of aldehyde dehydrogenase-2 attenuates chronic alcohol exposure-induced apoptosis, change in akt and pim signalling in liver

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 5-6, 2009, Pages 463-468

  Guo, Rui ^a,c   Zhong, Li ^b,c   Ren, Jun ^a  

^a UNIVERSITY OF WYOMING   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c HEBEI UNIVERSITY   (China)

Author keywords

Acetaldehyde; Alcohol; Aldehyde dehydrogenase 2 (ALDH2); Apoptosis; Liver

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 2; CASPASE 3; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE PIM; PROTEIN P53; SERINE PROTEINASE OMI; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ASSAY; IMMUNOBLOTTING; LIVER; LIVER INJURY; MALE; MOUSE; NONHUMAN; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION;

ALCOHOL DRINKING; ALDEHYDE DEHYDROGENASE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ETHANOL; FEMALE; LIVER; MICE; MICE, TRANSGENIC; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; PROTEIN CARBONYLATION; PROTO-ONCOGENE PROTEINS C-PIM-1; SIGNAL TRANSDUCTION; TIME FACTORS; UP-REGULATION;

EID: 65349145485     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05152.x     Document Type: Article

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