Cystathionine protects against endoplasmic reticulum stress-induced lipid accumulation, tissue injury, and apoptotic cell death

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 31994-32005

  Maclean, Kenneth N ^a   Greiner, Lori S ^a   Evans, Jeffrey R ^a   Sood, Sudesh K ^c   Lhotak, Sarka ^c   Markham, Neil E ^a   Stabler, Sally P ^b   Allen, Robert H ^b   Austin, Richard C ^c   Balasubramaniam, Vivek ^a   Jiang, Hua ^a  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c ST JOSEPH S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC CELL DEATH; CONNECTIVE TISSUES; DISEASE STATE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ER STRESS; EXPERIMENTAL EVIDENCE; HEPATIC STEATOSIS; HOMOCYSTEINES; LIPID ACCUMULATIONS; MENTAL RETARDATION; PATHOGENIC FACTORS; PATHOGENIC MUTATION; PROTECTIVE EFFECTS; REACTION CATALYZED; STRESS-INDUCED; SYNTHASES; THERAPEUTIC POTENTIALS; THIOETHERS; TISSUE INJURY; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

AMINO ACIDS; CELL CULTURE; CELL MEMBRANES; COLLAGEN; ELECTRIC CIRCUIT BREAKERS; HANDICAPPED PERSONS; MAMMALS; MUSCULOSKELETAL SYSTEM; REACTION INTERMEDIATES; SYNTHESIS (CHEMICAL); TISSUE;

CELL DEATH;

CYSTATHIONINE; TUNICAMYCIN;

ACUTE KIDNEY TUBULE NECROSIS; AMINO ACID SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; HISTOPATHOLOGY; HOMOCYSTINURIA; HUMAN; HUMAN CELL; KIDNEY PARENCHYMA; LIPID STORAGE; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; TISSUE INJURY; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CYSTATHIONINE; CYSTATHIONINE BETA-SYNTHASE; ENDOPLASMIC RETICULUM; HEK293 CELLS; HEP G2 CELLS; HOMOCYSTINURIA; HUMANS; LIPIDS; MALE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MUTATION; NECROSIS; NEUROBLASTOMA; PROTEIN DENATURATION; TUNICAMYCIN;

MAMMALIA;

EID: 84866407109     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.355172     Document Type: Article

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