Genome-wide analysis shows association of epigenetic changes in regulators of Rab and Rho GTPases with spinal muscular atrophy severity

European Journal of Human Genetics

Volumn 21, Issue 9, 2013, Pages 988-993

  Zheleznyakova, Galina Y ^a,b   Voisin, Sarah ^b   Kiselev, Anton V ^c   Sällman Almén, Markus ^b   Xavier, Miguel J ^b   Maretina, Marianna A ^a   Tishchenko, Lyudmila I ^a   Fredriksson, Robert ^b   Baranov, Vladislav S ^a,c   Schiöth, Helgi B ^b  

^a ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^b UPPSALA UNIVERSITY   (Sweden)

^c D O OTT RESEARCH INSTITUTE OF OBSTETRICS   (Russian Federation)

Author keywords

CpG sites; DNA methylation profile; SMA

Indexed keywords

ACTIN; ARHGAP22 PROTEIN; BIOLOGICAL MARKER; CDK2AP1 PROTEIN; CHML PROTEIN; CYTSB PROTEIN; RAB PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SLC23A2 PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AXONOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE SEVERITY; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; GENE DELETION; GENE DOSAGE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; HUMAN; MALE; PHENOTYPE; PRIORITY JOURNAL; SPINAL MUSCULAR ATROPHY;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; GENE ONTOLOGY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INFANT; MALE; MUSCULAR ATROPHY, SPINAL; RAB GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 84882454987     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2012.293     Document Type: Article

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