Rabs grab motors: Defining the connections between Rab GTPases and motor proteins

Current Opinion in Cell Biology

Volumn 14, Issue 1, 2002, Pages 69-75

  Hammer III, John A ^a   Wu, Xufeng S ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL RECEPTOR; GUANOSINE TRIPHOSPHATASE; MICROTUBULE PROTEIN; RAB PROTEIN;

HUMAN; IMAGING; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVIEW; TRANSPORT VESICLE;

EID: 0036468368     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(01)00296-4     Document Type: Review

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2. SNARE-mediated membrane fusion
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4. GTP-bound forms of Rab6 induce redistribution of Golgi proteins into the endoplasmic reticulum
5. The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis
6. The human kinesin-like protein RB6K is under tight cell cycle control and is essential for cytokinesis
7. Arf proteins bind to mitotic kinesin-like protein (MKLP-1) in a GTP-dependent fashion
8. Inhibition of Rab5 GTPase activity stimulates membrane fusion in endocytosis
9. Translocation and clustering of endosomes and lysosomes depends on microtubules
10. Rab5 regulates motility of early endosomes on microtubules
11. Rab33b regulates intra-Golgi transport and utilizes a novel kinesin as an effector
12. Functions of unconventional myosins
13. Class V myosins
14. Determinants of skin color: Melanocytes and melanization
15. Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function in vivo
16. Novel myosin heavy chain encoded by murine dilute coat color locus
17. Ultrastructural observations on melanosome aggregation in genetically defective melanocytes of the mouse
18. Cultured melanocytes from dilute mice exhibit dendritic morphology and altered melanosome distribution
19. The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role for myosin V in melanosome transport
20. Griscelli desease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene
21. Mutations in Rab27a cause Griscelli syndrome associated with haemophagocytic syndrome
22. A mutation in Rab27a causes the vesicle transport defects observed in ashen mice
23. Rab27a: A key to melanosome transport in human melanocytes
24. Rab27a regulates the peripheral distribution of melanosomes in melanocytes
25. Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle
26. Myosin V colocalizes with melanosomes and subcortical actin bundles not associated with stress fibers in human epidermal melanocytes
27. Subcellular localization of myosin V in the B16 melanoma cells, a wild type cell line for the dilute gene
28. Myosin V associates with melanosomes in mouse melanocytes: Evidence that myosin V is an organelle motor
29. The effects of genotype and cell environment on melanoblast differentiation in the house mouse
30. Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice
31. Cloning and characterization of myr6, an unconventional myosin of the dilute/myosin-V family
32. Myosin Vb is associated with the plasma membrane recycling systems
33. Rab GTPases coordinate endocytosis
34. Polarization of cell growth in yeast. II. The role of the cortical actin cytoskeleton
35. Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast
36. The COOH-terminal domain of Myo2p, a yeast myosin V, has a direct role in secretory vesicle targeting
37. The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis
38. The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles
39. The role of Myo2p, a yeast class V myosin, in vesicular transport
40. Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles
41. Suppression of a myosin defect by a kinesin-related gene
42. Immunofluorescence localization of the unconventional myosin, Myo2p, and the putative kinesin-related protein, Smy1p, to the same regions of polarized growth in Saccharomyces cerevisiae
43. Smy1p, a kinesin-related protein that does not require microtubules
44. The yeast kinesin-related protein Smy1p exerts its effects on the class V myosin Myo2p via a physical interaction
45. Cooperation between microtubule- and actin-based motor proteins
46. Direct interaction of microtubule- and actin-based motors
47. Motor protein receptors: Moonlighting on other jobs
48. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
49. Defective granule exocytosis in Rab27a-deficient lymphocytes from ashen mice
50. Rab27a is required for regulated secretion in cytotoxic T lymphocytes