Possible functional role of NSPs in cancer

Cell Cycle

Volumn 7, Issue 12, 2008, Pages 1810-1827

  D'Agostino, Luca ^b   Giordano, Antonio ^a  

^a TEMPLE UNIVERSITY   (United States)

^b NONE

Author keywords

Apoptosis; B23; Cancer; Cell division; NSP

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALPONIN; COMPLEMENTARY DNA; NEUROENDOCRINE SPECIFIC PROTEIN; NEUROENDOCRINE SPECIFIC PROTEIN 5A3A; NEUROENDOCRINE SPECIFIC PROTEIN 5A3B; NUCLEOPHOSMIN; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL DIVISION; FLUORESCENCE ACTIVATED CELL SORTING; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS; NEOPLASM; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TESTIS;

EID: 47249112191     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.12.6023     Document Type: Article

References (73)

1. Sang N, Fath DM, Giordano A. A gene highly expressed in tumor cells encodes novel structure proteins. Oncogene 2004; 23:9438-46.
2. Djinovic Carugo K, Banuelos S, Saraste M. Crystal structure of a calponin homology domain. Nat Struct Biol 1997; 3:175-9.
3. Banuelos S, Saraste M, Djinovic Carugo K. Structural comparisons of calponin homology domains: implications for actin binding. Structure 1998; 6:1419-31.
4. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brokks MW, Weinberg RA. Creation of human tumour cells with defined genetic elements. Nature 1999; 400:464-8.
5. Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002; 347:1593-603.
6. Hartwell LH, Kastan MB. Cell cycle control and cancer. Science 1994; 266:1821-8.
7. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
8. Russo A, Migliavacca M, Zanna I, Macaluso M, Gebbia N, Bazan N. Encycl Hum Genome 2003; (in press).
9. Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature 1997; 386:761-3.
10. Galkin VE, Orlova A, Fattoum A, Walsh MP, Egelman EH. The CH-domain of calponin does not determine the modes of calponin binding to F-actin. J Mol Biol 2006; 359:478-85.
11. Gimona M, Mital R. The single CH domain of calponin is neither sufficient nor necessary for F-actin binding. J Cell Sci 1998; 111:1813-21.
12. Iakoucheva LM, Radivojac P, Brown CJ, O'Connor TR, Sikes JG, Obradovic Z, Dunker AK. The importance of intrinsic disorder for protein phosphorylation. Nucleic Acids Res 2004; 32:1037-49.
13. Beltrao P and Serrano L. Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions. Plos Comput Biol 2005; 1:26.
14. Bustos DM, Iglesias AA. Intrinsic disorder is a key characteristic in partners that bind 14-3-3 proteins. Proteins 2006; 63:35-42.
15. Uversky VN. Natively unfolded proteins: a point where biology waits for physics. Protein Sci 2002; 4:739-56.
16. Dunker AK, et al. Intrinsically disordered protein. J Mol Graph Model 2001; 1:26-59.
17. Neduva V, Russell RB. Linear motifs: evolutionary interaction switches. FEBS Lett 2005; 579:3342-5.
18. Puntervoll P, et al. ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Res 2003; 31:3625-30.
19. Wootton JC, Federhen S. Analysis of compositionally biased regions in sequence databases. Methods Enzymol 1996; 266:554-71.
20. Albà MM, Laskowski RA, Hancock JM. Detecting cryptically simple protein sequences using the SIMPLE algorithm. Bioinformatics 2002; 18:672-8.
21. Promponas VJ, Enright AJ, Tsoka S, Kreil DP, Leroy C, Hamodrakas S, Sander C, Ouzounis CA. CAST: an iterative algorithm for the complexity analysis of sequence tracts. Complexity analysis of sequence tracts. Bioinformatics 2000; 16:915-22.
22. Wan H, Li L, Federhen S, Wootton JC. Discovering simple regions in biological sequences associated with scoring schemes. J Comput Biol 2003; 10:171-85.
23. Wise MJ. 0j.py: a software tool for low complexity proteins and protein domains. Bioinformatics 2001; 17:288-95.
24. Shin SW, Kim SM. A new algorithm for detecting low-complexity regions in protein sequences. Bioinformatics 2005; 21:160-70.
25. Lanz RB, Wieland S, Hug M, Rusconi S. A transcriptional repressor obtained by alternative translation of a trinucleotide repeat. Nucleic Acids Res 1995; 23:138-45.
26. Hancock JM, Simon M. Simple sequence repeats in proteins and their significance for network evolution. Gene 2005; 345:113-8.
27. Byers TJ, Husain-Chishti A, Dubreuil RR, Branton D, Goldstein LS. Sequence similarity of the amino-terminal domain of Drosophila beta spectrin to alpha actinin and dystrophin. J Cell Biol 1989; 109:1633-41.
28. Davison MD, Baron MD, Critchley DR, Wootton JC. Structural analysis of homologous repeated domains in alpha-actinin and spectrin. Int J Biol Macromol 1989; 11:81-90.
29. Thomas GH, Newbern EC, Korte CC, Bales MA, Muse SV, Clark AG, Kiehart DP. Intragenic duplication and divergence in the spectrin superfamily of proteins. Mol Biol Evol 1997; 14:1285-95.
30. Viel A. Alpha-actinin and spectrin structures: an unfolding family story. FEBS Lett 1999; 460:391-4.
31. De Matteis MA, Morrow JS. Spectrin tethers and mesh in the biosynthetic pathway. J Cell Sci 2000; 113:2331-43.
32. Phillips MD, Thomas GH. Brush border spectrin is required for early endosome recycling in Drosophila. J Cell Sci 2006; 119:1361-70.
33. Djinovic-Carugo K, Young P, Gautel M, Saraste M. Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments. Cell 1999; 98:537-46.
34. Fan J, Beck KA. A role for the spectrin superfamily member Syne-1 and kinesin II in cytokinesis. J Cell Sci 2004; 117:619-29.
35. Sridharan D, Brown M, Lambert WC, McMahon LW, Lambert MW. Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links. J Cell Sci 2003; 116:823-35.
36. Enomoto T, Lindström MS, Jin A, Ke H, Zhang Y. Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability. J Biol Chem 2006; 281:18463-72.
37. Okuda M, Horn HF, Tarapore P, Tokuyama Y, Smulian AG, Chan PK, Knudsen ES, Hofmann IA, Snyder JD, Bove KE, Fukasawa K. Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication. Cell 2000; 103:127-40.
38. Colombo E, Marine JC, Danovi D, Falini B, Pelicci PG. Nucleophosmin regulates the stability and transcriptional activity of p53. Nat Cell Biol 2002; 4:529-33.
39. Szebeni A, Olson MO. Nucleolar protein B23 has molecular chaperone activities. Protein Sci 1999; 8:905-12.
40. Olson MO, Wallace MO, Herrera AH, Marshall-Carlson L, Hunt RC. Preribosomal ribonucleoprotein particles are a major component of a nucleolar matrix fraction. Biochemistry 1986; 25:484-91.
41. Dumbar TS, Gentry GA, Olson MO. Interaction of nucleolar phosphoprotein B23 with nucleic acids. Biochemistry 1989; 28:9495-501.
42. Savkur RS, Olson MO. Preferential cleavage in pre-ribosomal RNA by protein B23 endoribonuclease. Nucleic Acids Res 1998; 26:4508-15.
43. Szebeni A, Herrera JE, Olson MO. Interaction of nucleolar protein B23 with peptides related to nuclear localization signals. Biochemistry 1995; 34:8037-42.
44. Gottesfeld JM, Forbes DJ. Mitotic repression of the transcriptional machinery. Trends Biochem Sci 1997; 22:197-202.
45. Peter M, Nakagawa J, Doree M, Labbe JC, Nigg EA. Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Cell 1990; 60:791-801.
46. Zatsepina OV, Todorov IT, Philipova RN, Krachmarov CP, Trendelenburg MF, Jordan EG. Cell cycle-dependent translocations of a major nucleolar phosphoprotein, B23, and some characteristics of its variants. Eur J Cell Biol 1997; 73:58-70.
47. Zatsepina OV, Rousselet A, Chan PK, Olson MO, Jordan EG, Bornens M. The nucleolar phosphoprotein B23 redistributes in part to the spindle poles during mitosis. J Cell Sci 1999; 112:455-66.
48. Dundr M, Misteli T, Olson MO. The dynamics of postmitotic reassembly of the nucleolus. J Cell Biol 2000; 150:433-46.
49. Okuwaki M, Tsujimoto M, Nagata K. The RNA binding activity of a ribosome biogenesis factor, nucleophosmin/B23, is modulated by phosphorylation with a cell cycle-dependent kinase and by association with its subtype. Mol Biol Cell 2002; 13:2016-30.
50. Grisendi S, Mecucci C, Falini B, Pandolfi PP. Nucleophosmin and cancer. Nat Rev Cancer 2006; 6:493-505.
51. Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci USA 1998; 95:8292-7.
52. Weber HO, Samuel T, Rauch P, Funk JO. Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways. Oncogene 2002; 21:3207-12.
53. Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997; 420:25-7.
54. Seavey SE, Holubar M, Saucedo LJ, Perry ME. The E7 oncoprotein of human papillomavirus type 16 stabilizes p53 through a mechanism independent of p19(ARF). J Virol 1999; 73:7590-8.
55. Kim YT, Zhao M. Aberrant cell cycle regulation in cervical carcinoma. Yonsei Med J 2005; 46:597-613.
56. Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K, Pandolfi PP. Role of nucleophosmin in embryonic development and tumorigenesis. Nature 2005; 437:147-53.
57. Itahana K, Bhat KP, Jin A, Itahana Y, Hawke D, Kobayashi R, Zhang Y. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol Cell 2003; 12:1151-64.
58. ARF tumor suppressor with ribosomes. J Biol Chem 2006; 281:38080-8.
59. Prestayko AW, Olson MO, Busch H. Phosphorylation of proteins of ribosomes and nucleolar preribosomal particles in vivo in Novikoff hepatoma ascites cells. FEBS Lett 1997; 44:131-5.
60. Olson MO, et al. Preribosomal ribonucleoprotein particles are a major component of a nucleolar matrix fraction. Biochemistry 1986; 25:484-91.
61. Fan X, Liu Y, Chen JJ. Downregulation of p21 contributes to apoptosis induced by HPV E6 in human mammary epithelial cells. Apoptosis 2005; 10:63-73.
62. Finzer P, Aguilar-Lemarroy A, Rosl F. The role of human papillomavirus oncoproteins E6 and E7 in apoptosis. Cancer Lett 2002; 188:15-24.
63. Rapp L, Chen JJ. The papillomavirus E6 proteins. Biochim Biophys Acta 1998; 1378:1-19.
64. Vogt M, Butz K, Dymalla S, Semzow J, Hoppe-Seyler F. Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoprotein. Oncogene 2006; 25:4009-15.
65. Benchimol S. p53-dependent pathways of apoptosis. Cell Death Differ 2001; 8:1049-51.
66. Rose A, Meier I. Scaffolds, levers, rods and springs: diverse cellular functions of long coiledcoil proteins. Cell Mol Life Sci 2004; 61:1996-2009.
67. Chen Z, Indjeian VB, McManus M, Wang L, Dynlacht BD. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Dev Cell 2002; 3:339-50.
68. Ewing RM, et al. Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol 2007; 3:89.
69. Zhang H, Shi X, Paddon H, Hampong M, Dai W, Pelech S. B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1. J Biol Chem 2004; 279:35726-34.
70. Liu X, Liu Z, Jang SW, Ma Z, Shinmura K, Kang S, Dong S, Chen J, Fukasawa K, Ye K. Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival. Proc Natl Acad Sci USA 2007; 104:9679-84.
71. ARF, nucleophosmin (NPM/B23), and cancer. Hist J 2006; 37:239-51.
72. Van Dartel M, Cornelissen PW, Redeker S, Tarkkanen M, Knuutila S, Hogendoorn PC, Westerveld A, Gomes I, Bras J, Hulsebos TJ. Amplification of 17p11.2 approximately p12, including PMP22, TOP3A and MAPK7, in high-grade osteosarcoma. Cancer Genet Cytogenet 2002; 139:91-6.
73. Van Dartel M, Leenstra S, Troost D, Hulsebos TJ. Infrequent but high-level amplification of 17p11.2 approximately p12 in human glioma. Cancer Genet Cytogenet 2003; 140:162-6.