-
1
-
-
0003964363
-
-
American Cancer Society American Cancer Society: Atlanta
-
American Cancer Society. Cancer Facts & Figures. American Cancer Society: Atlanta, 2007.
-
(2007)
Cancer Facts & Figures
-
-
-
2
-
-
84882452093
-
Smad4/TGF-b pathway: Signaling pathways in pancreatic pathogenesis
-
In Neoptolemos JP, Buchler M, Errutia R (eds)Springer: New York
-
Norris AM, Korc M. Smad4/TGF-b pathway: signaling pathways in pancreatic pathogenesis. In: Neoptolemos JP, Buchler M, Errutia R (eds) Pancreatic Cancer. Springer: New York, 2009.
-
(2009)
Pancreatic Cancer
-
-
Norris, A.M.1
Korc, M.2
-
3
-
-
0033872039
-
Genetic progression in the pancreatic ducts
-
Hruban RH, Wilentz RE, Kern SE. Genetic progression in the pancreatic ducts. Am J Pathol 2000; 156: 1821-1825.
-
(2000)
Am J Pathol
, vol.156
, pp. 1821-1825
-
-
Hruban, R.H.1
Wilentz, R.E.2
Kern, S.E.3
-
4
-
-
0036239123
-
K-ras p53 and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: A molecular panel correlates with and supplements cytologic diagnosis
-
van Heek T, Rader AE, Offerhaus GJ, McCarthy DM, Goggins M, Hruban RH et al. K-ras, p53, and DPC4 (MAD4) alterations in fine-needle aspirates of the pancreas: a molecular panel correlates with and supplements cytologic diagnosis. Am J Clin Pathol 2002; 117: 755-765.
-
(2002)
Am J Clin Pathol
, vol.117
, pp. 755-765
-
-
Van Heek, T.1
Rader, A.E.2
Offerhaus, G.J.3
McCarthy, D.M.4
Goggins, M.5
Hruban, R.H.6
-
6
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
-
7
-
-
0031694080
-
Transfection of the type i TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer
-
Wagner M, Kleeff J, Lopez ME, Bockman I, Massaque J, Korc M. Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer. Int J Cancer 1998; 78: 255-260.
-
(1998)
Int J Cancer
, vol.78
, pp. 255-260
-
-
Wagner, M.1
Kleeff, J.2
Lopez, M.E.3
Bockman, I.4
Massaque, J.5
Korc, M.6
-
8
-
-
0029810920
-
Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition
-
Baldwin RL, Friess H, Yokoyama M, Lopez ME, Kobrin MS, Buchler MW et al. Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition. Int J Cancer 1996; 67: 283-288.
-
(1996)
Int J Cancer
, vol.67
, pp. 283-288
-
-
Baldwin, R.L.1
Friess, H.2
Yokoyama, M.3
Lopez, M.E.4
Kobrin, M.S.5
Buchler, M.W.6
-
9
-
-
0033573974
-
Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer
-
Kleeff J, Maruyama H, Friess H, Buchler MW, Falb D, Korc M. Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Biochem Biophys Res Commun 1999; 255: 268-273.
-
(1999)
Biochem Biophys Res Commun
, vol.255
, pp. 268-273
-
-
Kleeff, J.1
Maruyama, H.2
Friess, H.3
Buchler, M.W.4
Falb, D.5
Korc, M.6
-
10
-
-
2442696750
-
Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer
-
Arnold NB, Ketterer K, Kleeff J, Friess H, Buchler MW, Korc M. Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Res 2004; 64: 3599-3606.
-
(2004)
Cancer Res
, vol.64
, pp. 3599-3606
-
-
Arnold, N.B.1
Ketterer, K.2
Kleeff, J.3
Friess, H.4
Buchler, M.W.5
Korc, M.6
-
11
-
-
0027131252
-
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
-
Friess H, Yamanaka Y, Buchler M, Ebert M, Beger HG, Gold LI et al. Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 1993; 105: 1846-1856.
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Buchler, M.3
Ebert, M.4
Beger, H.G.5
Gold, L.I.6
-
12
-
-
79961226547
-
A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFbeta in pancreatic cancer cells
-
Sempere LF, Gunn JR, Korc M. A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFbeta in pancreatic cancer cells. Cancer Biol Ther 2011; 12: 198-207.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 198-207
-
-
Sempere, L.F.1
Gunn, J.R.2
Korc, M.3
-
13
-
-
70450247207
-
Mucins in cancer: Function, prognosis and therapy
-
Kufe DW. Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 2009; 9: 874-885.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.W.1
-
14
-
-
9144268394
-
Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy
-
Moniaux N, Andrianifahanana M, Brand RE, Batra SK. Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy. Br J Cancer 2004; 91: 1633-1638.
-
(2004)
Br J Cancer
, vol.91
, pp. 1633-1638
-
-
Moniaux, N.1
Andrianifahanana, M.2
Brand, R.E.3
Batra, S.K.4
-
15
-
-
2442568891
-
MUC1 and MUC2 in pancreatic neoplasia
-
Levi E, Klimstra DS, Andea A, Basturk O, Adsay NV. MUC1 and MUC2 in pancreatic neoplasia. J Clin Pathol 2004; 57: 456-462.
-
(2004)
J Clin Pathol
, vol.57
, pp. 456-462
-
-
Levi, E.1
Klimstra, D.S.2
Andea, A.3
Basturk, O.4
Adsay, N.V.5
-
16
-
-
0028180345
-
Altered expression of MUC2, MUC4, and MUC5 Mucin Genes in Pancreas Tissues and Cancer Cell Lines
-
Balague C, Gambus G, Carrato C, Porchet N, Aubert JP, Kim YS et al. Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines. Gastroenterology 1994; 106: 1054-1061.
-
(1994)
Gastroenterology
, vol.106
, pp. 1054-1061
-
-
Balague, C.1
Gambus, G.2
Carrato, C.3
Porchet, N.4
Aubert, J.P.5
Kim, Y.S.6
-
17
-
-
0033858759
-
Human MUC4 mucin cDNA and its variants in pancreatic carcinoma
-
Choudhury A, Moniaux N, Winpenny JP, Hollingsworth MA, Aubert JP, Batra SK. Human MUC4 mucin cDNA and its variants in pancreatic carcinoma. J Biochem 2000; 128: 233-243.
-
(2000)
J Biochem
, vol.128
, pp. 233-243
-
-
Choudhury, A.1
Moniaux, N.2
Winpenny, J.P.3
Hollingsworth, M.A.4
Aubert, J.P.5
Batra, S.K.6
-
18
-
-
0035678782
-
Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: A potential role of MUC4 as a tumor marker of diagnostic significance
-
Andrianifahanana M, Moniaux N, Schmied BM, Ringel J, Friess H, Hollingsworth MA et al. Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. Clin Cancer Res 2001; 7: 4033-4040.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4033-4040
-
-
Andrianifahanana, M.1
Moniaux, N.2
Schmied, B.M.3
Ringel, J.4
Friess, H.5
Hollingsworth, M.A.6
-
19
-
-
0030958706
-
Interaction of the DF3/MUC1 breast carcinoma- associated antigen and beta-catenin in cell adhesion
-
Yamamoto M, Bharti A, Li Y, Kufe D. Interaction of the DF3/MUC1 breast carcinoma- associated antigen and beta-catenin in cell adhesion. J Biol Chem 1997; 272: 12492-12494.
-
(1997)
J Biol Chem
, vol.272
, pp. 12492-12494
-
-
Yamamoto, M.1
Bharti, A.2
Li, Y.3
Kufe, D.4
-
20
-
-
0035929643
-
The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin
-
Li Y, Ren J, Yu W, Li Q, Kuwahara H, Yin L et al. The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin. J Biol Chem 2001; 276: 35239-35242.
-
(2001)
J Biol Chem
, vol.276
, pp. 35239-35242
-
-
Li, Y.1
Ren, J.2
Yu, W.3
Li, Q.4
Kuwahara, H.5
Yin, L.6
-
21
-
-
0035918199
-
Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
-
Schroeder JA, Thompson MC, Gardner MM, Gendler SJ. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 2001; 276: 13057-13064.
-
(2001)
J Biol Chem
, vol.276
, pp. 13057-13064
-
-
Schroeder, J.A.1
Thompson, M.C.2
Gardner, M.M.3
Gendler, S.J.4
-
22
-
-
17544395847
-
Muc4/ sialomucin complex, the intramembrane ErbB2 ligand, in cancer and epithelia: To protect and to survive
-
Carraway KL, Perez A, Idris N, Jepson S, Arango M, Komatsu M et al. Muc4/ sialomucin complex, the intramembrane ErbB2 ligand, in cancer and epithelia: to protect and to survive. Prog Nucleic Acid Res Mol Biol 2002; 71: 149-185.
-
(2002)
Prog Nucleic Acid Res Mol Biol
, vol.71
, pp. 149-185
-
-
Carraway, K.L.1
Perez, A.2
Idris, N.3
Jepson, S.4
Arango, M.5
Komatsu, M.6
-
23
-
-
3042773498
-
The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage
-
Pohler E, Craig AL, Cotton J, Lawrie L, Dillon JF, Ross P et al. The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage. Mol Cell Proteomics 2004; 3: 534-547.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 534-547
-
-
Pohler, E.1
Craig, A.L.2
Cotton, J.3
Lawrie, L.4
Dillon, J.F.5
Ross, P.6
-
24
-
-
23744499653
-
Diversity of the protein disulfide isomerase family: Identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family
-
Persson S, Rosenquist M, Knoblach B, Khosravi-Far R, Sommarin M, Michalak M. Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family. Mol Phylogenet Evol 2005; 36: 734-740.
-
(2005)
Mol Phylogenet Evol
, vol.36
, pp. 734-740
-
-
Persson, S.1
Rosenquist, M.2
Knoblach, B.3
Khosravi-Far, R.4
Sommarin, M.5
Michalak, M.6
-
25
-
-
66349091311
-
The protein disulfide isomerase AGR2 is essential for production of intestinal mucus
-
Park SW, Zhen G, Verhaeghe C, Nakagami Y, Nguyenvu LT, Barczak AJ et al. The protein disulfide isomerase AGR2 is essential for production of intestinal mucus. Proc Natl Acad Sci USA 2009; 106: 6950-6955.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6950-6955
-
-
Park, S.W.1
Zhen, G.2
Verhaeghe, C.3
Nakagami, Y.4
Nguyenvu, L.T.5
Barczak, A.J.6
-
26
-
-
84455192726
-
Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis
-
Higa A, Mulot A, Delom F, Bouchecareilh M, Nguyen DT, Boismenu D et al. Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis. J Biol Chem 2011; 286: 44855-44868.
-
(2011)
J Biol Chem
, vol.286
, pp. 44855-44868
-
-
Higa, A.1
Mulot, A.2
Delom, F.3
Bouchecareilh, M.4
Nguyen, D.T.5
Boismenu, D.6
-
27
-
-
18144426063
-
Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas
-
Liu D, Rudland PS, Sibson DR, Platt-Higgins A, Barraclough R. Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas. Cancer Res 2005; 65: 3796-3805.
-
(2005)
Cancer Res
, vol.65
, pp. 3796-3805
-
-
Liu, D.1
Rudland, P.S.2
Sibson, D.R.3
Platt-Higgins, A.4
Barraclough, R.5
-
28
-
-
33645674889
-
Prognostic relevance of AGR2 expression in breast cancer
-
Fritzsche FR, Dahl E, Pahl S, Burkhardt M, Luo J, Mayordomo E et al. Prognostic relevance of AGR2 expression in breast cancer. Clin Cancer Res 2006; 12: 1728-1734.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1728-1734
-
-
Fritzsche, F.R.1
Dahl, E.2
Pahl, S.3
Burkhardt, M.4
Luo, J.5
Mayordomo, E.6
-
29
-
-
13844253776
-
Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival
-
Kristiansen G, Pilarsky C, Wissmann C, Kaiser S, Bruemmendorf T, Roepcke S et al. Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival. J Pathol 2005; 205: 359-376.
-
(2005)
J Pathol
, vol.205
, pp. 359-376
-
-
Kristiansen, G.1
Pilarsky, C.2
Wissmann, C.3
Kaiser, S.4
Bruemmendorf, T.5
Roepcke, S.6
-
30
-
-
77956170869
-
The pro-metastatic protein anterior gradient-2 predicts poor prognosis in tamoxifen-treated breast cancers
-
Hrstka R, Nenutil R, Fourtouna A, Maslon MM, Naughton C, Langdon S et al. The pro-metastatic protein anterior gradient-2 predicts poor prognosis in tamoxifen-treated breast cancers. Oncogene 2010; 29: 4838-4847.
-
(2010)
Oncogene
, vol.29
, pp. 4838-4847
-
-
Hrstka, R.1
Nenutil, R.2
Fourtouna, A.3
Maslon, M.M.4
Naughton, C.5
Langdon, S.6
-
31
-
-
33645751864
-
Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients
-
Innes HE, Liu D, Barraclough R, Davies MP, O'Neill PA, Platt-Higgins A et al. Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. Br J Cancer 2006; 94: 1057-1065.
-
(2006)
Br J Cancer
, vol.94
, pp. 1057-1065
-
-
Innes, H.E.1
Liu, D.2
Barraclough, R.3
Davies, M.P.4
O'Neill, P.A.5
Platt-Higgins, A.6
-
32
-
-
70349758603
-
Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma
-
Riener MO, Pilarsky C, Gerhardt J, Grutzmann R, Fritzsche FR, Bahra M et al. Prognostic significance of AGR2 in pancreatic ductal adenocarcinoma. Histol Histopathol 2009; 24: 1121-1128.
-
(2009)
Histol Histopathol
, vol.24
, pp. 1121-1128
-
-
Riener, M.O.1
Pilarsky, C.2
Gerhardt, J.3
Grutzmann, R.4
Fritzsche, F.R.5
Bahra, M.6
-
33
-
-
77953440843
-
Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia
-
Chen R, Pan S, Duan X, Nelson BH, Sahota RA, de Rham S et al. Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia. Mol Cancer 2010; 9: 149.
-
(2010)
Mol Cancer
, vol.9
, pp. 149
-
-
Chen, R.1
Pan, S.2
Duan, X.3
Nelson, B.H.4
Sahota, R.A.5
De Rham, S.6
-
34
-
-
79952245615
-
Anterior gradient 2: A novel player in tumor cell biology
-
Brychtova V, Vojtesek B, Hrstka R. Anterior gradient 2: a novel player in tumor cell biology. Cancer Lett 2011; 304: 1-7.
-
(2011)
Cancer Lett
, vol.304
, pp. 1-7
-
-
Brychtova, V.1
Vojtesek, B.2
Hrstka, R.3
-
35
-
-
0032500762
-
HAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines
-
Thompson DA, Weigel RJ. hAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines. Biochem Biophys Res Commun 1998; 251: 111-116.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 111-116
-
-
Thompson, D.A.1
-
36
-
-
40749106656
-
Gene expression patterns in pancreatic tumors, cells and tissues
-
Lowe AW, Olsen M, Hao Y, Lee SP, Taek Lee K, Chen X et al. Gene expression patterns in pancreatic tumors, cells and tissues. PLoS ONE 2007; 2: e323.
-
(2007)
PLoS ONE
, vol.2
-
-
Lowe, A.W.1
Olsen, M.2
Hao, Y.3
Lee, S.P.4
Taek Lee, K.5
Chen, X.6
-
37
-
-
0037379406
-
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
-
Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C et al. Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol 2003; 162: 1151-1162.
-
(2003)
Am J Pathol
, vol.162
, pp. 1151-1162
-
-
Iacobuzio-Donahue, C.A.1
Maitra, A.2
Olsen, M.3
Lowe, A.W.4
Van Heek, N.T.5
Rosty, C.6
-
38
-
-
81155126043
-
AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D
-
Dumartin L, Whiteman HJ, Weeks ME, Hariharan D, Dmitrovic B, Iacobuzio- Donahue CA et al. AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D. Cancer Res 2011; 71: 7091-7102.
-
(2011)
Cancer Res
, vol.71
, pp. 7091-7102
-
-
Dumartin, L.1
Whiteman, H.J.2
Weeks, M.E.3
Hariharan, D.4
Dmitrovic, B.5
Iacobuzio-Donahue, C.A.6
-
39
-
-
39049141776
-
The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation
-
Wang Z, Hao Y, Lowe AW. The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation. Cancer Res 2008; 68: 492-497.
-
(2008)
Cancer Res
, vol.68
, pp. 492-497
-
-
Wang, Z.1
Hao, Y.2
Lowe, A.W.3
-
40
-
-
54249104147
-
Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival
-
Ramachandran V, Arumugam T, Wang H, Logsdon CD. Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival. Cancer Res 2008; 68: 7811-7818.
-
(2008)
Cancer Res
, vol.68
, pp. 7811-7818
-
-
Ramachandran, V.1
Arumugam, T.2
Wang, H.3
Logsdon, C.D.4
-
41
-
-
42449133874
-
The application of differential display as a gene profiling tool
-
Chang KC, Komm B, Arnold NB, Korc M. The application of differential display as a gene profiling tool. Methods Mol Biol 2007; 383: 31-40.
-
(2007)
Methods Mol Biol
, vol.383
, pp. 31-40
-
-
Chang, K.C.1
Komm, B.2
Arnold, N.B.3
Korc, M.4
-
42
-
-
9044243025
-
Homozygous deletion map at 18q21.1 in pancreatic cancer
-
Hahn SA, Hoque AT, Moskaluk CA, da Costa LT, Schutte M, Rozenblum E et al. Homozygous deletion map at 18q21.1 in pancreatic cancer. Cancer Res 1996; 56: 490-494.
-
(1996)
Cancer Res
, vol.56
, pp. 490-494
-
-
Hahn, S.A.1
Hoque, A.T.2
Moskaluk, C.A.3
Da Costa, L.T.4
Schutte, M.5
Rozenblum, E.6
-
43
-
-
0038459055
-
A comprehensive characterization of pancreatic ductal carcinoma cell lines: Towards the establishment of an in vitro research platform
-
Sipos B, Moser S, Kalthoff H, Torok V, Lohr M, Kloppel G. A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform. Virchows Arch 2003; 442: 444-452.
-
(2003)
Virchows Arch
, vol.442
, pp. 444-452
-
-
Sipos, B.1
Moser, S.2
Kalthoff, H.3
Torok, V.4
Lohr, M.5
Kloppel, G.6
-
44
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin CH, Miyazono K, ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997; 390: 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
45
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF[beta]-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier J-M. Direct binding of Smad3 and Smad4 to critical TGF[beta]-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 1998; 17: 3091-3100.
-
(1998)
EMBO J
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien Ten Dijke, P.3
Huet, S.4
Gauthier, J.-M.5
-
47
-
-
0032516862
-
Identification and functional characterization of a smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-OEr, activin, and bone morphogenetic proteininducible enhancer
-
Jonk LJC, Itoh S, Heldin C-H, ten Dijke P, Kruijer W. Identification and functional characterization of a smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-OEr, activin, and bone morphogenetic proteininducible enhancer. J Biol Chem 1998; 273: 21145-21152.
-
(1998)
J Biol Chem
, vol.273
, pp. 21145-21152
-
-
Ljc, J.1
Itoh, S.2
Heldin, C.-H.3
Ten Dijke, P.4
Kruijer, W.5
-
48
-
-
33645140228
-
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease
-
Zheng W, Rosenstiel P, Huse K, Sina C, Valentonyte R, Mah N et al. Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease. Genes Immun 2006; 7: 11-18.
-
(2006)
Genes Immun
, vol.7
, pp. 11-18
-
-
Zheng, W.1
Rosenstiel, P.2
Huse, K.3
Sina, C.4
Valentonyte, R.5
Mah, N.6
-
49
-
-
0029834067
-
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
-
Lagna G, Hata A, Hemmati-Brivanlou A, Massague J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 1996; 383: 832-836.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
Massague, J.4
-
50
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B et al. Human Smad3 and Smad4 are sequence-specific transcription activators. Mol Cell 1998; 1: 611-617.
-
(1998)
Mol Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
Vogelstein, B.6
-
51
-
-
0028954215
-
Signal transduction, packaging and secretion of mucins
-
Forstner G. Signal transduction, packaging and secretion of mucins. Annu Rev Physiol 1995; 57: 585-605.
-
(1995)
Annu Rev Physiol
, vol.57
, pp. 585-605
-
-
Forstner, G.1
-
52
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 2003; 4: 437-450.
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
Rajapakse, V.4
King, C.5
Jacobetz, M.A.6
-
53
-
-
33645824724
-
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
-
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF et al. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci USA 2006; 103: 5947-5952.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5947-5952
-
-
Bardeesy, N.1
Aguirre, A.J.2
Chu, G.C.3
Cheng, K.H.4
Lopez, L.V.5
Hezel, A.F.6
-
54
-
-
33751251034
-
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer
-
Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P et al. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes Dev 2006; 20: 3130-3146.
-
(2006)
Genes Dev
, vol.20
, pp. 3130-3146
-
-
Bardeesy, N.1
Cheng, K.H.2
Berger, J.H.3
Chu, G.C.4
Pahler, J.5
Olson, P.6
-
55
-
-
80052127297
-
Deletion of rb accelerates pancreatic carcinogenesis by oncogenic kras and impairs senescence in premalignant lesions
-
Carriere C, Gore AJ, Norris AM, Gunn JR, Young AL, Longnecker DS et al. Deletion of rb accelerates pancreatic carcinogenesis by oncogenic kras and impairs senescence in premalignant lesions. Gastroenterology 2011; 141: 1091-1101.
-
(2011)
Gastroenterology
, vol.141
, pp. 1091-1101
-
-
Carriere, C.1
Gore, A.J.2
Norris, A.M.3
Gunn, J.R.4
Young, A.L.5
Longnecker, D.S.6
-
56
-
-
34249878202
-
Mucin expression profile in pancreatic cancer and the precursor lesions
-
Nagata K, Horinouchi M, Saitou M, Higashi M, Nomoto M, Goto M et al. Mucin expression profile in pancreatic cancer and the precursor lesions. J Hepatobiliary Pancreat Surg 2007; 14: 243-254.
-
(2007)
J Hepatobiliary Pancreat Surg
, vol.14
, pp. 243-254
-
-
Nagata, K.1
Horinouchi, M.2
Saitou, M.3
Higashi, M.4
Nomoto, M.5
Goto, M.6
-
57
-
-
15844387270
-
Mad-related genes in the human
-
Riggins GJ, Thiagalingam S, Rozenblum E, Weinstein CL, Kern SE, Hamilton SR et al. Mad-related genes in the human. Nat Genet 1996; 13: 347-349.
-
(1996)
Nat Genet
, vol.13
, pp. 347-349
-
-
Riggins, G.J.1
Thiagalingam, S.2
Rozenblum, E.3
Weinstein, C.L.4
Kern, S.E.5
Hamilton, S.R.6
-
59
-
-
0034032009
-
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
-
Wilentz RE, Iacobuzio-Donahue CA, Argani P, McCarthy DM, Parsons JL, Yeo CJ et al. Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 2000; 60: 2002-2006.
-
(2000)
Cancer Res
, vol.60
, pp. 2002-2006
-
-
Wilentz, R.E.1
Iacobuzio-Donahue, C.A.2
Argani, P.3
McCarthy, D.M.4
Parsons, J.L.5
Yeo, C.J.6
-
61
-
-
75149190938
-
ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer
-
Zhang X, Ali TZ, Hua Z. ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer. Cancer Res 2010; 70: 240-248.
-
(2010)
Cancer Res
, vol.70
, pp. 240-248
-
-
Zhang, X.1
Ali, T.Z.2
Hua, Z.3
-
62
-
-
77954061337
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker AGR2 in the hepatocarcinoma cell line HepG2
-
Ambolet-Camoit A, Bui LC, Pierre S, Chevallier A, Marchand A, Coumoul X et al. 2,3,7,8-Tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker AGR2 in the hepatocarcinoma cell line HepG2. Toxicol Sci 2010; 115: 501-512.
-
(2010)
Toxicol Sci
, vol.115
, pp. 501-512
-
-
Ambolet-Camoit, A.1
Bui, L.C.2
Pierre, S.3
Chevallier, A.4
Marchand, A.5
Coumoul, X.6
-
63
-
-
33745106870
-
Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue
-
Wilson CL, Sims AH, Howell A, Miller CJ, Clarke RB. Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue. Endocr Relat Cancer 2006; 13: 617-628.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 617-628
-
-
Wilson, C.L.1
Sims, A.H.2
Howell, A.3
Miller, C.J.4
Clarke, R.B.5
-
64
-
-
19444381367
-
AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer
-
Zhang JS, Gong A, Cheville JC, Smith DI, Young CY. AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer. Genes Chromosomes Cancer 2005; 43: 249-259.
-
(2005)
Genes Chromosomes Cancer
, vol.43
, pp. 249-259
-
-
Zhang, J.S.1
Gong, A.2
Cheville, J.C.3
Smith, D.I.4
Young, C.Y.5
-
65
-
-
79953061206
-
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
-
Roy LD, Sahraei M, Subramani DB, Besmer D, Nath S, Tinder TL et al. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 2011; 30: 1449-1459.
-
(2011)
Oncogene
, vol.30
, pp. 1449-1459
-
-
Roy, L.D.1
Sahraei, M.2
Subramani, D.B.3
Besmer, D.4
Nath, S.5
Tinder, T.L.6
-
66
-
-
79959891751
-
Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis
-
Besmer DM, Curry JM, Roy LD, Tinder TL, Sahraei M, Schettini J et al. Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. Cancer Res 2011; 71: 4432-4442.
-
(2011)
Cancer Res
, vol.71
, pp. 4432-4442
-
-
Besmer, D.M.1
Curry, J.M.2
Roy, L.D.3
Tinder, T.L.4
Sahraei, M.5
Schettini, J.6
-
67
-
-
20444433569
-
Smad7 abrogates transforming growth factor-beta1- mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein
-
Boyer Arnold N, Korc M. Smad7 abrogates transforming growth factor-beta1- mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. J Biol Chem 2005; 280: 21858-21866.
-
(2005)
J Biol Chem
, vol.280
, pp. 21858-21866
-
-
Boyer Arnold, N.1
Korc, M.2
-
68
-
-
34248372925
-
The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
-
Carriere C, Seeley ES, Goetze T, Longnecker DS, Korc M. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc Natl Acad Sci USA 2007; 104: 4437-4442.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4437-4442
-
-
Carriere, C.1
Seeley, E.S.2
Goetze, T.3
Longnecker, D.S.4
Korc, M.5
-
69
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002; 129: 2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
|